A new technique is helping researchers to pinpoint genetic information that contributes to cancer development.
A research team, led by Professor Thomas Preiss from the John Curtin School of Medical Research at The Australian National University, has used a new mapping technique to reveal tell-tale "sign posts" in DNA’s lesser-known relative, RNA - ribonucleic acid.
"RNA acts as a messenger, carrying genetic information to the parts of the cell in which proteins are made. Enzymes in the cell can modify RNA, leaving ’sign posts’, known as m5C sites," Professor Preiss said.
"The enzymes that modify RNA have proven connections to cancer and stem cell biology. Understanding the patterns of these modifications will help cancer researchers focus their attention on the contribution that RNA makes to cancer."