- Medicine - 16:00 Worldwide bee epidemic linked to human cause: colony trafficking
- Medicine - 14:00 International spotlight on TUM medical and engineering research
- Medicine - 13:02 Fall in one-to- one nursing care of very sick new- borns linked to higher death rate - Provision fell by around a third in England between 2008 and 2012
- Medicine - 12:18 ’Parent coach’ helps improve the well- child checkup experience
- Medicine - 10:17 Better definition needed for reasonable medical certainty in child abuse cases
- Mathematics - Feb 10 Computational tools could change the way sleep apnea is treated
- Medicine - Feb 10 Sneezing produces complex fluid cascade, not a simple spray
- Medicine - Feb 10 Fertility lab leader seeks key to ’good eggs’
- Life Sciences - Feb 10 Tiger poo pregnancy test nothing to sniff at
- Medicine - Feb 9 HRH The Duke of York brings Pitch@Palace Tour to the University of Glasgow
- Computer Science - Feb 9 New Neubauer Collegium projects to explore complex human questions
- Medicine - Feb 9 U of’T gains 34 new Canada Research Chairs
- Environmental Sciences - Feb 9 Desilting ponds in India benefit farmers, environment
- Medicine - Feb 9 New device to get people with paralysis back on their feet
- Medicine - Feb 9 Proportion of home deaths falls in South- West Scotland
- Medicine - Feb 9 ’Molecular movie’ opens door to new cancer treatments
Rooted in evidence: a public health response to dementia
Research programmes at the Cambridge Institute of Public Health focus on common chronic disorders. Currently under the spotlight is dementia and a major new project that will underpin improved prevention, screening and patient care.
Crucial to the success of the registry is allowing the population to become part of the enterprise... as true partners in the process of public health research and action."—Professor Carol Brayne
Today, more than 600,000 people in England are affected by dementia - a progressive and terminal brain disease that, as more people live longer, is predicted to affect twice this number within 30 years. It’s an escalating public health problem that the Department of Health has stated is a national priority.
However, according to a report published by the National Audit Office in 2010, there is too little joined-up working between health and social care services for people with dementia, a situation echoed by Professor Carol Brayne, Director of the Cambridge Institute of Public Health (CIPH): "What patients and families tell us is that there are problems with fragmentation of care for dementia, with not enough information about what’s available and what pattern of services works best."
Brayne and colleagues within CIPH (see panel), together with collaborators from Cambridgeshire and Peterborough NHS Foundation Trusts and partners from the Cambridge University Health Partnership, realised that a new approach was needed to underpin the delivery of improved dementia care, as well as to further research on dementia screening, treatment and prevention. Their aim is to build a dementia registry to support both service and research.
Evidence road map
"Until now, not enough of the research evidence cited in dementia guidelines has been generated on the populations to whom the treatments will be applied - the older old, aged 80 and above," explained Brayne. "This could be resolved by an up-to-date dementia registry based on the systematic collection of all data relating to individual patients with dementia combined with a road map of evidence, both qualitative and quantitative, right the way through from prevention to palliative care."
Physicians and public health specialists need accurate and up-to-date data to compare therapies, reduce risks and set standards, and in recent decades registries have become a key part for monitoring illnesses such as cancer, infectious disease and diabetes. Because registries contain information on patient history, diagnosis, treatment and social care, they are valuable not only for making important public health decisions about treatment and co-ordinated care but also for identifying gaps that require further research.
The complex process of designing and delivering a registry for dementia in Cambridgeshire and Peterborough has now begun. It aims to be the first truly population-based register nationwide to link all services in the area. Developing a registry is not without its challenges, as Brayne, who chairs the steering committee, explained: "There are very important data governance and social and ethical issues to address, including the label itself - not everybody who might meet the criteria for dementia would wish to call themselves demented. It’s a very emotive label and there’s a lot of fear. One of things we want to do is help with destigmatisation."
After a scoping study commissioned by the Collaboration for Leadership in Applied Health Research and Care for Cambridgeshire and Peterborough (CLAHRC CP), work began last year to develop the system and the first phase of the registry is under way, working with primary and secondary care.
Two phases that will sit alongside each other have been planned: one (now in active development) is a care pathway registry to link data directly from GPs relating to various stages in the patients’ journey through inpatients, outpatients, community care and related services; and another will create a research registry of people with dementia who are suitable, and would welcome the opportunity, to participate in research. Both phases have the backing of the National Institute for Health Research (NIHR) Dementias and Neurodegenerative Diseases Research Network, which is also actively supporting the development of registers nationwide, and now endorsed through the Prime Minister’s Challenge.
"The previous lack of a dementia register across the Cambridgeshire and Peterborough areas has meant there has been limited information for planning services," added Brayne. "Going forward, stakeholders will be able to monitor trends and plan ahead for the ageing population. We hope this initiative will also improve safety and efficacy of day-to-day clinical management for people with dementia, improve outcomes and maximise efficiency."
Data for health
The dementia registry is one element of a more ambitious vision: to integrate data with health care planning and research for a whole range of common chronic diseases "so that doctors have the right information at the right level in front of them, and researchers have the appropriate permission to recruit patients for research studies."
Dementia is a current priority but, long term, what Brayne and colleagues are calling Data4Health Cambridgeshire will draw from CIPH’s work on conditions such as cancer, cardiovascular disease, neurodegenerative diseases, osteoporosis and metabolic diseases, and hope to join this all the way through to local authorities and voluntary sectors. The work of CIPH partners such as the Eastern Region Public Health Observatory and Eastern Cancer Registration and Information Centre will be crucial to push forward health information sharing for care policy and research.
"The key benefit of this approach is that results from world-class researchers are immediately open to the assessment of their impact on a population," explained Brayne. "For instance, for dementia, we have a well-established programme of ageing and neuroscience research across the University. Data4Health will feed into these programmes and be fed by them."
Examples include research in the Biomedical Research Unit in Dementia and the Cambridge Centre for Brain Repair on the molecular basis and potential for screening and treatment of neurodegenerative diseases; research at the Cambridge Centre for Ageing and Neuroscience on how individuals can best retain cognitive abilities into old age; and longitudinal studies, some of which began running in the 1980s, led by Brayne at CIPH and colleagues in the Department of Psychiatry to investigate depression, physical disability and early detection of dementia. In addition, researchers in the Behaviour and Health Research Unit and in the Centre for Diet and Activity Research are gathering evidence on life-course behaviours that optimise the chance of a healthy old age.
"Crucial to the success of the registry," added Brayne, "is allowing the whole population to become part of the enterprise. They can become more familiar with the benefits of a research and experimental approach to generating knowledge, and ultimately they can seek to drive it themselves - as true partners in the process of public health research and action."
Cambridge Institute of Public Health
In just 20 years, Cambridge’s Institute of Public Health (CIPH) has grown to encompass so many partnerships that a ’tree of life’ diagram (see top of this page) is needed to make sense of the Institute’s scope. In April it was selected as a member of the National Institute for Health Research School for Public Health Research (NIHR SfPHR).
Through the establishment of large-scale population resources, CIPH’s individual partners investigate the influences of genetic and lifestyle factors in chronic diseases and then translate this evidence into the development and evaluation of preventative interventions.
In April this year, CIPH was selected as one of eight leading academic centres to collaborate as part of the new NIHR SfPHR, which will place emphasis on what works practically, can be applied across the whole country and better meets the needs of policy makers, practitioners and the public.
"Public health must connect with all relevant areas affecting health," said Professor Carol Brayne, Director of CIPH. "It’s about seeing the large picture by piecing together the component parts. Above all it’s about creating, assessing and working out how to implement the best possible evidence.
"Decisions on the shape and content of health services aren’t easy," she continued. "Public health can help by providing the distance and independence required, and can then link these to the commissioning of the appropriate services for populations."
CIPH is a strategic partnership between the NHS, the University of Cambridge Department of Public Health and Primary Care, and three Medical Research Council units: the Biostatistics Unit, the Epidemiology Unit and the Human Nutrition Unit. The NHS members are the Eastern Region Public Health Observatory, the Regional Epidemiology Unit of the Health Protection Agency, and the Eastern Cancer Registration and Information Centre. The Foundation for Genomics and Population Health is the first charitable status member of CIPH.
CIPH has also supported several initiatives that span the Institute: the Cambridge Centre for Health Services Research, the Centre for Diet and Activity Research, the Behaviour and Health Research Unit, and the Collaboration for Leadership in Applied Health Research and Care for Cambridgeshire and Peterborough.
Last job offers
- Civil Engineering - 10.2
Wissenschaftliche/r Mitarbeiter/in (Postdoc mit Tenure Track)
- Civil Engineering - 10.2
Wissenschaftliche/r Mitarbeiter/in (Postdoc mit Tenure Track)
- Environmental Sciences - 9.2
Leiter/in Fachstelle Unterstützung der Abfallverursacher (80–100%)
- Social Sciences - 9.2
Research & Innovatin Advisor Social Sciences & Humanities / Security (80%)
- Law/Forensics - 9.2
Leiter/in Competence Center Management and Law, Fachgruppe Recht und Studienrichtung Management &...
- Mechanical Engineering - 5.2
Dozent/-in für Produktentwicklung Maschinenbau (100 %)
- Mechanical Engineering - 9.2
Full Professor of Ship Hydromechanics
- Psychology - 9.2
Assistant professor in Work and Organizational Psychology
- Arts and Design - 5.2
Universitätsprofessorin / Universitätsprofessor für das Fach Elementare Musik- und Tanzpädagogik (befristet)...
- Social Sciences - 5.2
Universitätsprofessorin / Universitätsprofessor für das Fach Komposition (BV gem. Â§ 98 UG )
- Law/Forensics - 9.2
Professur für Öffentliches Recht an der Rechtswissenschaftlichen Fakultät
- Literature/Linguistics - 9.2
- Business/Economics - 10.2
Assistant Professor in Sensory Science (Full time/Part time - job share available)
- Chemistry - 10.2
Associate Professor (or Professorship) of Physical and Theoretical Chemistry
- Medicine/Pharmacology - 10.2
Assistant Professor - Pediatric Cardiology
- Medicine/Pharmacology - 9.2
Medicine - Assistant or Associate Professor WOT (AA7797)