The specific risk factors for the development of Parkinson's disease in women remain little studied and poorly known. Exposure to the hormones involved in female reproductive life is one of the avenues explored at the Epidemiology and Population Health Research Center (CESP) by a research team from Inserm, Université Paris-Saclay, Université de Versailles Saint-Quentin-en-Yvelines with Institut Gustave Roussy, which compared the reproductive characteristics of nearly 1,200 women with Parkinson's disease with those of other women from the E3N cohort

More than 15,000 packaged products on the French market currently contain nitrites or nitrates. Although commonly used to ensure better preservation of processed meats (ham, sausages, etc.), the safety of these food additives is the subject of debate. Nitrites and nitrates are also naturally found in various foods (particularly vegetables) and in drinking water, but agricultural and industrial practices can increase their levels.

Emulsifiers are food additives used to improve the texture and extend the shelf life of foods. They are found in many processed foods (ice creams, packaged cakes, sauces...), although their harmful effects on intestinal balance have been demonstrated.

In the weeks that follow the birth of a child, both parents are likely to develop depression. Paternity leave, recognized for its benefits on family balance, child development and male-female equality, could be one of the keys to preventing this condition that affects one in ten fathers and almost two in ten mothers. Using data from over 10,000 heterosexual couples participating in the Elfe

"Awarding the Inserm Prizes is a key point in the Institute's life, enabling us to showcase the various talents of our staff and the great wealth of the research we conduct to form a common front for the health of our fellow citizens.

Tuberculosis affects 1 million children each year; less than half of them are diagnosed and treated for the disease, which leads to more than 200,000 deaths.

An international consortium has identified rare variants in two new genes that markedly increase the risk of developing Alzheimer's disease (AD).

Cisplatin is a chemotherapy indicated to fight tumors in many types of cancer. However, it does have major side effects - especially kidney toxicity, that can lead to acute kidney failure.

The team from the Human Genetics of Infectious Diseases Laboratory of the Necker-Enfants malades AP-HP Hospital, Inserm, Université Paris Cité within the Imagine Institute, leading the international consortium COVID Human Genetic Effort ( www.

Pressing the gas pedal and lifting the brake at the same time is the innovative idea of Dr. Nicolas Manel, Inserm researcher and team leader at the Institut Curie (Immunity and Cancer Unit - Institut Curie, Inserm) to improve the response to immunotherapies.

Anxiety disorders are the most common psychiatric conditions in adolescence, with nearly one in three individuals affected. Some of these disorders - such as panic disorder or generalized anxiety disorder

Ebola epidemics occur periodically in various sub-Saharan African countries. While vaccines exist and have already received WHO Prequalification against the Zaire ebolavirus species, it is essential to pursue and intensify efforts to supplement the available data to develop a safe and effective Ebola vaccine strategies in adults and children alike.

While great progress has been made in recent years in the understanding of autism spectrum disorder (ASD), its underlying molecular mechanisms remain fairly poorly documented.

Both sickle cell disease and beta-thalassemia are genetic disorders that affect hemoglobin, and as such are categorized as beta-hemoglobinopathies. A team of scientists from Inserm, Université Paris Cité and the Paris Public Hospitals Group AP-HP at the Imagine Institute has shown the efficacy of a gene therapy approach to treat these two disorders. The principle is to reactivate in patients the production of fetal hemoglobin, a protein whose expression usually ceases after birth. In a study published in

People with liver disease caused by eating too much sugar and fat could be at increased risk of developing serious neurological conditions like depression or dementia. In a study examining the link between non-alcoholic fatty liver disease (NAFLD) and brain dysfunction, scientists at the Roger Williams Institute of Hepatology, affiliated to King's College London and the University of Lausanne, found an accumulation of fat in the liver causes a decrease in oxygen to the brain and inflammation to brain tissue - both of which have been proven to lead to the onset of severe brain diseases.

Several months after SARS-CoV-2 infection, some patients continue to have symptoms. This phenomenon, known as "post-COVID condition” or, more commonly, "long COVID”, remains poorly documented. In order to address this and improve patient care, research teams are trying to improve their understanding of the underlying biological and immunological mechanisms. In a new study, scientists from Inserm and Université de Montpellier at the Montpellier Cancer Research Institute, in collaboration with Montpellier University Hospital