Institut national de la santé et de la recherche médicale (INSERM)

Institut national de la santé et de la recherche médicale (INSERM)

Discipline: Health
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Aedes mosquitoes are the principal vectors of dengue and other arboviruses, including Zika, for which no vaccines or antiviral treatments currently exist. Understanding the factors that influence the transmission of arboviruses from mosquitoes to humans is therefore a priority because it could guide the implementation of public health measures that could limit or even prevent epidemics.
The specific risk factors for the development of Parkinson's disease in women remain little studied and poorly known. Exposure to the hormones involved in female reproductive life is one of the avenues explored at the Epidemiology and Population Health Research Center (CESP) by a research team from Inserm, Université Paris-Saclay, Université de Versailles Saint-Quentin-en-Yvelines with Institut Gustave Roussy, which compared the reproductive characteristics of nearly 1,200 women with Parkinson's disease with those of other women from the E3N cohort
More than 15,000 packaged products on the French market currently contain nitrites or nitrates. Although commonly used to ensure better preservation of processed meats (ham, sausages, etc.), the safety of these food additives is the subject of debate. Nitrites and nitrates are also naturally found in various foods (particularly vegetables) and in drinking water, but agricultural and industrial practices can increase their levels.
Fathers Who Take 2 Weeks Paternity Leave Are Considered Less Likely to Develop Postpartum Depression
In the weeks that follow the birth of a child, both parents are likely to develop depression. Paternity leave, recognized for its benefits on family balance, child development and male-female equality, could be one of the keys to preventing this condition that affects one in ten fathers and almost two in ten mothers. Using data from over 10,000 heterosexual couples participating in the Elfe
Ebola epidemics occur periodically in various sub-Saharan African countries. While vaccines exist and have already received WHO Prequalification against the Zaire ebolavirus species, it is essential to pursue and intensify efforts to supplement the available data to develop a safe and effective Ebola vaccine strategies in adults and children alike.
Both sickle cell disease and beta-thalassemia are genetic disorders that affect hemoglobin, and as such are categorized as beta-hemoglobinopathies. A team of scientists from Inserm, Université Paris Cité and the Paris Public Hospitals Group AP-HP at the Imagine Institute has shown the efficacy of a gene therapy approach to treat these two disorders. The principle is to reactivate in patients the production of fetal hemoglobin, a protein whose expression usually ceases after birth. In a study published in
People with liver disease caused by eating too much sugar and fat could be at increased risk of developing serious neurological conditions like depression or dementia. In a study examining the link between non-alcoholic fatty liver disease (NAFLD) and brain dysfunction, scientists at the Roger Williams Institute of Hepatology, affiliated to King's College London and the University of Lausanne, found an accumulation of fat in the liver causes a decrease in oxygen to the brain and inflammation to brain tissue - both of which have been proven to lead to the onset of severe brain diseases.
Several months after SARS-CoV-2 infection, some patients continue to have symptoms. This phenomenon, known as "post-COVID condition” or, more commonly, "long COVID”, remains poorly documented. In order to address this and improve patient care, research teams are trying to improve their understanding of the underlying biological and immunological mechanisms. In a new study, scientists from Inserm and Université de Montpellier at the Montpellier Cancer Research Institute, in collaboration with Montpellier University Hospital
