A Post Doctoral position in the EIC Pathfinder project Garden of Eve (NutriEV) in the field of innovative approaches to advancing the treatment of diabetes and optimized nutrition for healthy living | |
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Workplace | Copenhagen, Hovedstaden, Denmark |
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A Post Doctoral position in the EIC Pathfinder project Garden of Eve (NutriEV) in the field of innovative approaches to advancing the treatment of diabetes and optimized nutrition for healthy living We are offering one post doctoral position at the Copenhagen Center for Glycomics (CCG) with the Wandall Group, commencing from January 1st 2025 or after agreement. The position is fixed term for 3 years and full time (37 working hour in average per week). The candidate will be part of a EIC Pathfinder project promoting new technological solutions to advance the treatment of diabetes and developing optimized nutrition for healthy living and preclinical organoid models for advancing personalized medicine. Garden of Eve (NutriEV) : This project aims to revolutionize our understanding of nutrition and its connection to metabolic disorders by exploring the intricate roles of glycans and extracellular vesicles (EVs) in these processes. Traditionally, the digestive system has been viewed as a simple mechanism for breaking down food into molecular building blocks, with the gut microbiome playing a crucial role in this digestion. However, the alarming rise in diseases like obesity, diabetes, and metabolic syndrome suggests that our current understanding is incomplete. Recent research has uncovered the existence of EVs, nanoscale vesicles that transport proteins, lipids, nucleic acids, and glycans between cells, playing vital roles in maintaining tissue homeostasis and participating in various physiological and pathological processes. These EVs, particularly those enriched with glycoconjugates, exhibit unique glycosignatures that influence their interactions with target cells and their overall behavior within the body. Our project leverages advanced glycoproteomics, utilizing high-sensitivity liquid chromatography-mass spectrometry (LC-MS) to delve into the complex glycan and glycoprotein profiles of EVs and other biological samples. By studying the glycan composition of EVs, we aim to uncover specific glycoprotein changes associated with metabolic diseases. This approach will provide insights into how these molecular structures contribute to metabolic dysfunction and disease progression. In practical terms, our research holds the promise of developing precision medicine-based therapies and innovative diagnostic methods. By understanding how nutritional factors, gut microbiome, and EVs orchestrate metabolic processes and influence conditions like obesity and diabetes, we can pave the way for targeted interventions. This knowledge could lead to personalized dietary strategies that improve metabolic health, offering a more effective approach to managing and preventing these widespread diseases. Our research CCG is a cutting-edge interdisciplinary research and training Center located on the 10th floor of the new Mærsk Tower science building within the Department of Cellular and Molecular Medicine (ICMM). CCG has state-of-the-art facilities for mass spectrometry, mass photometry, flow cytometry, cell engineering, and glycan arrays, and group leaders hold diverse expertise in all areas of glycosciences. Our core valuables include glycoproteome data and bioinformatics tools, validated gene editing tools, glycoengineered cell libraries, and design matrices for the recombinant production of glycotherapeutics. CCG hosts an international seminar series, PhD courses in glycobiology and gene editing, and participates in ICMMs education program. Principal supervisor: Professor Hans H. Wandall, e-mail: hhwsund.ku.dk . Start date: 1 January 2025 or after agreement. Duration: 3 years. The successful candidate will conduct independent research related to the topics above at the Department of Cellular and Molecular Medicine (ICMM). We expect the candidate to engage in an active research environment and take part in student guidance. Profile Key criteria for the assessment of applicants for the postdoc position:
Other important criteria are :
Applicants should be highly organized and motivated to carry out research related to the topics described above. Candidates with prior experience in glycobiology, organoid models, virology, and/or quantitative glycoproteomics will receive advantaged consideration. Place of employment More information can be found at ?url=https%3A%2F%2Ficmm.ku.dk%2Fenglish%2F&module=jobs&id=2965320" target="_blank" rel="nofollow">?url=https%3A%2F%2Ficmm.ku.dk%2Fenglish%2F&module=jobs&id=2965320" target="_blank" rel="nofollow">https://icmm.ku.dk/english/ . Terms of employment The position is a fixed-term position for a period of 3 years commencing 1 January 2025 or after agreement. Foreign and Danish applicants may be eligible for tax reductions if they hold a PhD degree and have not lived in Denmark the last 10 years. The position is covered by the Job Structure for Academic Staff at Universities 2020. Questions Foreign applicants may find this link useful: ?url=https%3A%2F%2Fism.ku.dk%2F&module=jobs&id=2965320" target="_blank" rel="nofollow">?url=https%3A%2F%2Fism.ku.dk%2F&module=jobs&id=2965320" target="_blank" rel="nofollow">https://ism.ku.dk/ (International Staff Mobility). Application procedure
Deadline for applications: Wednesday 16 October 2024, 23.59 p.m. CEST . We reserve the right not to consider material received after the deadline, and not to consider applications that do not live up to the abovementioned requirements. The further process You can read about the recruitment process at ?url=https%3A%2F%2Femployment.ku.dk%2Ffaculty%2Frecruitment-process%2F&module=jobs&id=2965320" target="_blank" rel="nofollow">?url=https%3A%2F%2Femployment.ku.dk%2Ffaculty%2Frecruitment-process%2F&module=jobs&id=2965320" target="_blank" rel="nofollow">https://employment.ku.dk/faculty/recruitment-process/ . The applicant will be assessed according to the Ministerial Order no. 242 of 13 March 2012 on the Appointment of Academic Staff at Universities. The Faculty of Health and Medical Sciences comprises approximately 7,823 students, 1,886 PhD candidates and 5,100 employees. The faculty advances the field of health sciences through its core activities: research, teaching, knowledge sharing and communication. With basic research fields ranging from molecular studies to studies of society, the faculty contributes to a healthy future through its graduates, research findings and inventions benefitting patients and the community. Part of the International Alliance of Research Universities (IARU), and among Europe’s top-ranking universities, the University of Copenhagen promotes research and teaching of the highest international standard. Rich in tradition and modern in outlook, the University gives students and staff the opportunity to cultivate their talent in an ambitious and informal environment. An effective organisation - with good working conditions and a collaborative work culture - creates the ideal framework for a successful academic career. ContactHans H. Wandall E-mail: hhwsund.ku.dk InfoApplication deadline: 16-10-2024 Employment start: 01-01-2025 Working hours: Full time Department/Location: Department of Cellular and Molecular Medicine (ICMM) Search all vacancies | |
In your application, please refer to myScience.org and reference JobID 2965320. |
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