Drug test offers hope for Hep C patients

Scientists at the University have developed a laboratory technique that allows hepatitis C drugs to be tested for effectiveness on a particular individual before they are prescribed.

It will also help to monitor whether and when the virus becomes resistant to drugs and provide the means to evaluate the effectiveness of switching to other antiviral medicines.

Although the infection generally occurs with few or no immediate symptoms, long term carriers are at high risk of both liver disease and liver cancer.

Only one anti-viral treatment is currently available, which is effective in only half of cases and often with serious side effects such as severe fatigue and depression.

The team, led by Professor Peter Simmonds, then tested a range of drugs on the infected cells and analysed each drug’s effectiveness on each strain of the virus.

This new system will make it easier to select in advance the best treatment option for each individual patient, saving them from ineffective treatments with potentially serious side effects.

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