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Pharmacology - 20.09.2019
Antidepressants may reduce anxiety more than depressive symptoms
One of the most common antidepressants, sertraline, leads to an early reduction in anxiety symptoms, commonly found in depression, several weeks before any improvement in depressive symptoms, a UCL-led clinical trial has found. Published in The Lancet Psychiatry and funded by the National Institute for Health Research (NIHR), this is the largest-ever placebo-controlled trial of an antidepressant, which has not been funded by the pharmaceutical industry.

Pharmacology - Health - 20.09.2019
Breath-holding technique could improve outcomes for radiotherapy patients
A technique that will enable cancer patients to hold their breath during prolonged bouts of radiotherapy treatment has been developed by researchers at the University of Birmingham. In the study, published in Radiotherapy and Oncology , researchers demonstrated that, by safely increasing oxygen levels in the lungs and removing carbon dioxide from blood, it is possible for individuals to hold their breath for multiple four-minute periods during treatment.

Health - Pharmacology - 19.09.2019
One step closer to treating and preventing stomach flu thanks to new research model
One step closer to treating and preventing stomach flu thanks to new research model
Researchers at KU Leuven have developed a new research model to grow and study the human variant of the norovirus. The virus could thus far only be studied through a variant that occurs in mice. The new model, that is described in the journal PLOS Pathogens, should allow researchers to develop a treatment for stomach flu.

Health - Pharmacology - 19.09.2019
Advanced AI boosts clinical analysis of eye images
Advanced AI boosts clinical analysis of eye images
A fast and reliable machine learning tool, developed by the ARTORG Center, University of Bern and the Department of Ophthalmology, Inselspital brings Artificial Intelligence (AI) closer to clinical use in Ophthalmology. The novel method published in Nature Scientific Reports on September 19, 2019 presents a tool that reliably extracts meaning from extensive image data.

Pharmacology - Health - 18.09.2019
Positive results from Novartis five-year VERIFY study in type 2 diabetes demonstrate long-term clinical benefits of early combination treatment with Galvus and metformin
Early combination treatment strategy with vildagliptin (Galvus ) and metformin was superior to standard of care in newly diagnosed type 2 diabetes patients ,   The landmark VERIFY study is the first to investigate the long-term clinical benefits of this early combination strategy in type 2 diabetes (T2DM)   Novartis is committed to optimizing patient management of T2DM to achieve better glycemic control and favorable long-term clinical outcomes 

Pharmacology - 18.09.2019
Half of content in physicians’ notes may be inaccurate
FINDINGS An examination of how closely emergency department doctors' medical documentation aligned with the actual care they provided to patients found that half the content in the notes that go into the patient's electronic medical records was inaccurate. BACKGROUND The researchers initiated the study after noticing that many physicians were writing extensive notes — suggesting they spent a long time at the bedside evaluating their patients, a rare occurrence for emergency department physicians.

Health - Pharmacology - 18.09.2019
AI-based prognosis in intensive care: decision-relevant patterns identified in EEG of coma patients
AI-based prognosis in intensive care: decision-relevant patterns identified in EEG of coma patients
A reliable prognosis for coma patients in the intensive care unit is crucial. Improved transparency will boost the use of Artificial Intelligence (AI) to support end-of-life decisions. For the first time, a research team has succeeded in identifying specific patterns in Electro-Encephalogram (EEG) analyses that the deep-learning network uses for making prognosis decisions.

Health - Pharmacology - 17.09.2019
How animal research is helping fight antibiotic resistance
How animal research is helping fight antibiotic resistance
We explore how animal research is playing a vital role in the battle against antibiotic resistant superbugs. People do not expect to die from a simple infection. But that might change: the world is running out of effective antibiotics. For decades, diseases like bacterial gastroenteritis and colitis have not been a serious health threat, thanks to antibiotics.

Life Sciences - Pharmacology - 17.09.2019
Brain activity intensity drives need for sleep
Brain activity intensity drives need for sleep
The intensity of brain activity during the day, notwithstanding how long we've been awake, appears to increase our need for sleep, according to a new UCL study in zebrafish. The research, published in Neuron , found a gene that responds to brain activity in order to coordinate the need for sleep. It helps shed new light on how sleep is regulated in the brain.

Health - Pharmacology - 16.09.2019
Once-common hysterectomy technique linked to worse uterine cancer outcomes
Every year, nearly 700,000 American women have surgery to remove their uterus (hysterectomy) or uterine fibroids (myomectomy). A laparoscopic surgical technique once commonly used in these procedures could be worsening the outcomes for women who have undiagnosed uterine cancer at the time of the procedure, reports a Yale-led study in the Journal of Clinical Oncology.

Pharmacology - Innovation / Technology - 16.09.2019
Drugs cannot escape the NarcoReader
The University of Antwerp is coordinating a European project to increase efficiency in drug detection With the NarcoReader, the University of Antwerp is collaborating with its international partners to develop a high-tech device that is intended to make the detection of drugs quite a bit more efficient.

Health - Pharmacology - 16.09.2019
Childhood behaviour linked to taking paracetamol during pregnancy
A new study by the University of Bristol adds to evidence that links potential adverse effects of taking paracetamol during pregnancy. The research published today (Monday 16 September) in Paediatric and Perinatal Epidemiology examined whether there were any effects of taking paracetamol in mid-pregnancy and the behaviour of the offspring between the ages of 6 month and 11 years, with memory and IQ tested up until the age of 17.

Pharmacology - Health - 12.09.2019
Antibiotics reduce survival rates in cancer patients taking immunotherapy
Antibiotics reduce survival rates in cancer patients taking immunotherapy
Cancer patients on immunotherapy fare worse if they have recently taken antibiotics, with their response and overall survival rate 'crashing'. The findings come from a study of almost 200 cancer patients in the UK taking a type of immunotherapy called checkpoint inhibitors, part of the standard treatment pathway for cancer patients on the NHS.

Health - Pharmacology - 12.09.2019
Statins could protect older patients from severe pneumonia
Statins could be used to treat older patients admitted to hospital with a severe type of pneumonia, researchers at the University of Birmingham have found. A clinical trial, led by the University of Birmingham's Institute of Inflammation and Ageing , set out to determine if giving a high dose of a statin called simvastatin over a short period would improve immune system function for older adults who had been hospitalised with community acquired pneumonia with sepsis.

Pharmacology - Physics - 12.09.2019
A Single Dose for Good Measure: How an Anti-Nuclear-Contamination Pill Could Also Help MRI Patients
A Single Dose for Good Measure: How an Anti-Nuclear-Contamination Pill Could Also Help MRI Patients
Same pill designed to treat radiation poisoning could double as an anti-gadolinium-toxicity pill for MRI patients injected with commonly used contrast dye, says Berkeley Lab chemist W hen chemist Rebecca Abergel and her team at the U.S. Department of Energy's Lawrence Berkeley National Laboratory (Berkeley Lab) successfully developed an anti-radiation-poisoning pill in 2014 , they hoped it would never have to be used.

Pharmacology - 12.09.2019
Casts doubt on accuracy of mobile drug testing devices
Casts doubt on accuracy of mobile drug testing devices
Research at the University of Sydney Lambert Initiative for Cannabinoid Therapeutics suggests the devices currently used return both false positives and false negatives. New research conducted by the Lambert Initiative for Cannabinoid Therapeutics at the University of Sydney calls into question the reliability of the two devices that are currently being used for mobile drug testing (MDT) in NSW and other Australian states.

Health - Pharmacology - 11.09.2019
Brings personalised medicine to treat leukaemia one step closer
Scientists at the University of Birmingham have revealed the roles that different types of gene mutations play in causing blood cancers in a study that was the culmination of a decade's research. The findings of the team, led by Professor Constanze Bonifer and Professor Peter Cockerill of the University of Birmingham's Institute of Cancer and Genomic Studies , mean doctors are now one step closer to being able to provide tailored and targeted treatment specific to individual patients - increasing their chances of survival.

Health - Pharmacology - 11.09.2019
More die after surgery than from HIV, TB, and malaria combined - study
Around the world 4.2 million people die every year within 30 days after surgery - with half of these deaths occurring in lowand middle-income countries (LMICs), a new study reveals. There is also a significant unmet need for surgery in LMICs and researchers believe that if operations were provided for all patients who need them the number of global post-operative deaths would increase to 6.1 million.

Health - Pharmacology - 11.09.2019
Potential treatments for deadly tropical disease
Melioidosis is a tropical disease that claims an estimated 90,000 lives worldwide each year. There is no vaccine, and current treatments are hampered by the ability of the bacterium that causes the disease to resist even the strongest antibiotics. Hardy and lethal, that bacterium, Burkholderia pseudomallei, is classified by the Centers for Disease Control and Prevention as a potential bioweapon.

Pharmacology - Health - 11.09.2019
Can a DNA construction kit replace expensive antibody medication?
Researchers at KU Leuven in Belgium have developed a technique to make sheep produce new antibodies simply by injecting the DNA building blocks. This approach is much cheaper and more efficient than producing antibodies industrially and administering them afterwards. The study in animals with a similar size as humans brings us a step closer to the clinical use of antibody gene therapy.
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