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Health - Pharmacology - 17.09.2019
How animal research is helping fight antibiotic resistance
How animal research is helping fight antibiotic resistance
We explore how animal research is playing a vital role in the battle against antibiotic resistant superbugs. People do not expect to die from a simple infection. But that might change: the world is running out of effective antibiotics. For decades, diseases like bacterial gastroenteritis and colitis have not been a serious health threat, thanks to antibiotics.

Life Sciences - Pharmacology - 17.09.2019
Brain activity intensity drives need for sleep
Brain activity intensity drives need for sleep
The intensity of brain activity during the day, notwithstanding how long we've been awake, appears to increase our need for sleep, according to a new UCL study in zebrafish. The research, published in Neuron , found a gene that responds to brain activity in order to coordinate the need for sleep. It helps shed new light on how sleep is regulated in the brain.

Health - Pharmacology - 16.09.2019
Once-common hysterectomy technique linked to worse uterine cancer outcomes
Every year, nearly 700,000 American women have surgery to remove their uterus (hysterectomy) or uterine fibroids (myomectomy). A laparoscopic surgical technique once commonly used in these procedures could be worsening the outcomes for women who have undiagnosed uterine cancer at the time of the procedure, reports a Yale-led study in the Journal of Clinical Oncology.

Pharmacology - Innovation / Technology - 16.09.2019
Drugs cannot escape the NarcoReader
The University of Antwerp is coordinating a European project to increase efficiency in drug detection With the NarcoReader, the University of Antwerp is collaborating with its international partners to develop a high-tech device that is intended to make the detection of drugs quite a bit more efficient.

Health - Pharmacology - 16.09.2019
Childhood behaviour linked to taking paracetamol during pregnancy
A new study by the University of Bristol adds to evidence that links potential adverse effects of taking paracetamol during pregnancy. The research published today (Monday 16 September) in Paediatric and Perinatal Epidemiology examined whether there were any effects of taking paracetamol in mid-pregnancy and the behaviour of the offspring between the ages of 6 month and 11 years, with memory and IQ tested up until the age of 17.

Pharmacology - Health - 12.09.2019
Antibiotics reduce survival rates in cancer patients taking immunotherapy
Antibiotics reduce survival rates in cancer patients taking immunotherapy
Cancer patients on immunotherapy fare worse if they have recently taken antibiotics, with their response and overall survival rate 'crashing'. The findings come from a study of almost 200 cancer patients in the UK taking a type of immunotherapy called checkpoint inhibitors, part of the standard treatment pathway for cancer patients on the NHS.

Health - Pharmacology - 12.09.2019
Statins could protect older patients from severe pneumonia
Statins could be used to treat older patients admitted to hospital with a severe type of pneumonia, researchers at the University of Birmingham have found. A clinical trial, led by the University of Birmingham's Institute of Inflammation and Ageing , set out to determine if giving a high dose of a statin called simvastatin over a short period would improve immune system function for older adults who had been hospitalised with community acquired pneumonia with sepsis.

Pharmacology - Physics - 12.09.2019
A Single Dose for Good Measure: How an Anti-Nuclear-Contamination Pill Could Also Help MRI Patients
A Single Dose for Good Measure: How an Anti-Nuclear-Contamination Pill Could Also Help MRI Patients
Same pill designed to treat radiation poisoning could double as an anti-gadolinium-toxicity pill for MRI patients injected with commonly used contrast dye, says Berkeley Lab chemist W hen chemist Rebecca Abergel and her team at the U.S. Department of Energy's Lawrence Berkeley National Laboratory (Berkeley Lab) successfully developed an anti-radiation-poisoning pill in 2014 , they hoped it would never have to be used.

Pharmacology - 12.09.2019
Casts doubt on accuracy of mobile drug testing devices
Casts doubt on accuracy of mobile drug testing devices
Research at the University of Sydney Lambert Initiative for Cannabinoid Therapeutics suggests the devices currently used return both false positives and false negatives. New research conducted by the Lambert Initiative for Cannabinoid Therapeutics at the University of Sydney calls into question the reliability of the two devices that are currently being used for mobile drug testing (MDT) in NSW and other Australian states.

Health - Pharmacology - 11.09.2019
Brings personalised medicine to treat leukaemia one step closer
Scientists at the University of Birmingham have revealed the roles that different types of gene mutations play in causing blood cancers in a study that was the culmination of a decade's research. The findings of the team, led by Professor Constanze Bonifer and Professor Peter Cockerill of the University of Birmingham's Institute of Cancer and Genomic Studies , mean doctors are now one step closer to being able to provide tailored and targeted treatment specific to individual patients - increasing their chances of survival.

Health - Pharmacology - 11.09.2019
More die after surgery than from HIV, TB, and malaria combined - study
Around the world 4.2 million people die every year within 30 days after surgery - with half of these deaths occurring in lowand middle-income countries (LMICs), a new study reveals. There is also a significant unmet need for surgery in LMICs and researchers believe that if operations were provided for all patients who need them the number of global post-operative deaths would increase to 6.1 million.

Health - Pharmacology - 11.09.2019
Potential treatments for deadly tropical disease
Melioidosis is a tropical disease that claims an estimated 90,000 lives worldwide each year. There is no vaccine, and current treatments are hampered by the ability of the bacterium that causes the disease to resist even the strongest antibiotics. Hardy and lethal, that bacterium, Burkholderia pseudomallei, is classified by the Centers for Disease Control and Prevention as a potential bioweapon.

Pharmacology - Health - 11.09.2019
Can a DNA construction kit replace expensive antibody medication?
Researchers at KU Leuven in Belgium have developed a technique to make sheep produce new antibodies simply by injecting the DNA building blocks. This approach is much cheaper and more efficient than producing antibodies industrially and administering them afterwards. The study in animals with a similar size as humans brings us a step closer to the clinical use of antibody gene therapy.

Pharmacology - Health - 11.09.2019
Opioid treatment for teens’ Medications can help
Teens who misuse prescription or illicit opioids might benefit from opioid treatment medications, according to a new study led by a Yale researcher. An estimated 900 adolescents started to misuse opioid painkillers every day in 2017, and some of them turned to cheaper and more potent illegal opioids like heroin.

Health - Pharmacology - 10.09.2019
Dietary supplement may help with schizophrenia
Dietary supplement may help with schizophrenia
A dietary supplement, sarcosine, may help with schizophrenia as part of a holistic approach complementing antipsychotic medication, according to a UCL researcher. In an editorial published in the British Journal of Psychiatry , Professor David Curtis (UCL Genetics, Evolution & Environment and QMUL Centre for Psychiatry) suggests the readily available product could easily be incorporated into treatment plans, while calling for clinical trials to clarify the benefit and inform guidelines.

Pharmacology - Health - 10.09.2019
Multiple sclerosis therapy: scientists identify the Achilles' heel of a therapeutic antibody and find a solution to avoid the problem
Multiple sclerosis therapy: scientists identify the Achilles’ heel of a therapeutic antibody and find a solution to avoid the problem
An international research team led by the Institute for Research in Biomedicine, affiliated to the UniversitÓ della Svizzera italiana, has discovered why some patients with multiple sclerosis make an immune reaction that curtails the effectiveness of natalizumab, a therapeutic antibody used for the treatment of the disease and used this information to engineer a new version of the antibody that avoids this problem.

Health - Pharmacology - 09.09.2019
Blood test shows promise to aid better detection of lung cancer
Lung cancer can be spotted earlier and diagnosed more precisely with the help of a blood test, a major study carried out in Scotland has found. The Early Detection of Cancer of the Lung Scotland (ECLS) is the world's largest clinical biomarker trial looking into detecting early lung cancer using a blood test.

Pharmacology - Health - 05.09.2019
36% of proton pump inhibitor prescriptions for older adults may be unneeded
FINDINGS One in eight older adults was prescribed proton pump inhibitor drugs, which are used to treat gastric ulcers or to prevent gastrointestinal bleeding in those taking blood thinners. About 36 percent of those prescriptions were potentially unnecessary, a study found, primarily because people took them far longer than the often-recommended eight weeks.

Life Sciences - Pharmacology - 04.09.2019
Protein tangles linked with dementia seen for first time in patients’ brains
Scientists have visualised for the first time protein 'tangles' associated with dementia in the brains of patients who have suffered a single head injury. This is the finding of a new study led by scientists from Imperial College London, published Translational Medicine. In the early-stage study, researchers studied 21 patients who had suffered a moderate to severe head injury at least 18 years earlier (mostly from traffic accidents), as well as 11 healthy individuals who had not experienced a head injury.

Health - Pharmacology - 04.09.2019
When physicians integrate with hospitals, costs go up, Rice study says
When physicians integrate with hospitals, the cost of health care rises even though there's no evidence patients get better treatment, according to a new paper by experts at Rice University and Blue Cross and Blue Shield of Texas (BCBSTX). As hospitals gain more control over physicians, they may incentivize delivery of more services but not necessarily higher quality care, the researchers said in the paper, which appears in the Journal of General Internal Medicine.
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