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Pharmacology



Results 101 - 120 of 292.


Pharmacology - Life Sciences - 24.06.2019
New Therapy Promotes Vascular Repair Following Stroke
New Therapy Promotes Vascular Repair Following Stroke
Following a stroke, antibodies that inhibit the signaling molecule Nogo-A can help repair blood vessels in the affected brain regions. This also promotes the regaining of motor functions, researchers at the University of Zurich have shown in a mouse model. The study opens up new avenues for treatment.

Health - Pharmacology - 24.06.2019
Suggests healthcare guidelines should be updated for patients with certain adrenal tumours
Global guidelines on managing the care of patients diagnosed with common types of adrenal tumours should be updated, say researchers following a study carried out by an international collaboration. The research, a systematic review and meta-analysis published in Annals of Internal Medicine , is a collaboration between the University of Birmingham - part of Birmingham Health Partners (BHP) in the UK - and the Mayo Clinic in the US.

Pharmacology - Health - 24.06.2019
University of Birmingham in 4m project to train researchers to improve sight-saving treatments
Treatment of diseases of the back of the eye such as age-related macular degeneration (AMD) and diabetic eye disease is set to be improved with a 4m project led by Waterford Institute of Technology (WIT) in partnership with the University of Birmingham. The project, ORBITAL, will contribute to research which could lead to more widespread use of less invasive drug delivery methods such as eye drops, contact lenses and microneedle technologies, instead of traditional treatments such as injections.

Pharmacology - 20.06.2019
Connecting the dots: nitrogen dioxide over Siberian pipelines
Connecting the dots: nitrogen dioxide over Siberian pipelines
New maps that use information from the Copernicus Sentinel-5P satellite reveal emissions of nitrogen dioxide along a Siberian natural gas pipeline that connects the Urengoy gas field - the second-largest gas field in the world - with Europe. The Urengoy-Pomary-Uzhhorod pipeline is one of Russia's main natural gas export pipelines.

Health - Pharmacology - 19.06.2019
Federal guidelines may restrict women’s access to effective HIV protection
Restrictive recommendations for pre-exposure prophylaxis (or PrEP) issued by the Centers for Disease Control and Prevention (CDC) systematically disqualified nearly all women at risk for HIV and/or motivated to use the medication, researchers at the Yale School of Public Health and George Washington University have found.

Health - Pharmacology - 17.06.2019
Repurposing existing drugs or combining therapies could help in the treatment of autoimmune diseases
Research led by the University of Birmingham has found that re-purposing already existing drugs or combining therapies could be used to treat patients who have difficult to treat autoimmune diseases. Funded by Versus Arthritis, the research was led by the University of Birmingham's Institute of Inflammation and Ageing and is published in Proceedings of the National Academy of Sciences.

Pharmacology - Life Sciences - 17.06.2019
Preventing drugs from being transported
Certain membrane proteins specialise in transporting molecules out of cells - a problem for the efficacy of cancer medication and antibiotics. An international research team has investigated the transport mechanism of a bacterial membrane protein using an artificially produced antibody fragment. The transport proteins, called ABC exporters, are present, for instance, in the cell membranes of bacteria and in large quantities in cancer cells and are responsible for transporting small molecules out of the cells.

Life Sciences - Pharmacology - 17.06.2019
Tracking life’s first step: Two molecules ’awaken’ brand new genome
Within hours after fertilization, a unique genome forms from chromosomes contributed by the egg and sperm. However, this new genome is initially inactive and must be "awakened" to begin the transcription of its DNA and start embryonic development. How life's first step happens has long fascinated developmental biologists.

Pharmacology - Health - 14.06.2019
Compound with anti-aging effects passes human trial
Compound with anti-aging effects passes human trial
Urolithin A, a metabolite of biomolecules found in pomegranates and other fruits, could help slow certain aging processes. EPFL spin-off Amazentis, in conjunction with EPFL and the Swiss Institute of Bioinformatics, has published a paper Metabolism outlining the results of their clinical trial. It is a fact of life that skeletal muscles begin to lose strength and mass once a person reaches the age of 50.

Pharmacology - Health - 14.06.2019
New drug target for liver disease treatment
New drug target for liver disease treatment
A possible drug target for chronic liver disease has been identified by an international research collaboration involving a University of Queensland team. Professor Matt Sweet and Dr Divya Ramnath from UQ's Institute for Molecular Bioscience (IMB) worked with the study's senior author Dr Ekihiro Seki from Cedars-Sinai in Los Angeles, to identify genes linked to the progression of chronic liver disease.

Life Sciences - Pharmacology - 13.06.2019
GlaxoSmithKline taps UC’s CRISPR expertise to speed drug discovery
Jennifer Doudna and Jonathan Weissman are the key players in a new collaboration with GlaxoSmithKline to apply CRISPR techniques to the discovery of new drug targets, potentially leading to new therapies for genetic diseases.

Health - Pharmacology - 12.06.2019
Immunotherapy drug shows potential to cure advanced lung cancer
In a new study including Yale Cancer Center and Smilow Cancer Hospital researchers, the cancer immunotherapy drug pembrolizumab (Keytruda), increased survival for patients with advanced non-small cell lung cancer (NSCLC), a disease once considered an aggressive, and uniformly fatal cancer. The findings were presented at the American Society of Clinical Oncology (ASCO) annual meeting in Chicago.

Pharmacology - Health - 12.06.2019
New vulnerability found in viruses may help develop cure for the common cold
A team of researchers led by KU Leuven virologist Johan Neyts have discovered a new feature of so-called picornaviruses that may allow for the development of new antiviral medications for the common cold, polio, and other illnesses. Picornaviruses include rhinoviruses and enteroviruses. Rhinoviruses cause millions of cases of upper respiratory infections ("colds") yearly and contribute to asthma, and enteroviruses are responsible for millions of infections including cases such as meningitis, encephalitis and polio.

Health - Pharmacology - 12.06.2019
Checkmate for hepatitis B viruses in the liver
Checkmate for hepatitis B viruses in the liver
Infections with HBV are a global health problem. According to the World Health Organisation (WHO), more than 260 million people worldwide are chronically infected with the virus. Vaccination prevents new HBV infections, but for people who are chronic carriers of the virus, a cure has not yet been found.

Pharmacology - Chemistry - 11.06.2019
Learning from Nature's Bounty: New Libraries for Drug discovery
Learning from Nature’s Bounty: New Libraries for Drug discovery
Natural products, or their close derivatives, make some of our most potent medicines, among which macrocycles with their large carbon-rich ring systems are one class. The size and complexity of macrocycles has made it difficult to emulate and build on Nature's success in the laboratory.

Health - Pharmacology - 11.06.2019
Peptides that mimic ’good cholesterol’ reverse inflammatory bowel disease in mice
FINDINGS Peptides that mimic the function of HDL cholesterol, which has been dubbed “good cholesterol,” can treat the underlying inflammation associated with inflammatory bowel disease, or IBD, according to new research in mice. The same work revealed new details on how IBD can develop and what other types of drugs may work to treat the disease.

Health - Pharmacology - 11.06.2019
Are pharma payments to nurses impacting your healthcare?
Are pharma payments to nurses impacting your healthcare?
New analysis reveals pharmaceutical industry payments to Australian non-prescribing healthcare professionals such as nurses and pharmacists are substantial, raising questions around influence and a call for greater transparency. There's growing awareness that payments by the pharmaceutical industry to doctors - including the provision of even a modest meal at company-hosted events - are associated with poorer quality prescribing behaviour and increased healthcare costs.

Pharmacology - Chemistry - 10.06.2019
Healing compounds in scorpion venom
Stanford chemists have identified and synthesized two new healing compounds in scorpion venom that are effective at killing staph and tuberculosis bacteria. A scorpion native to Eastern Mexico may have more than just toxin in its sting. Researchers at Stanford University and in Mexico have found that the venom also contains two color-changing compounds that could help fight bacterial infections.

Health - Pharmacology - 10.06.2019
Vitamin D and colorectal cancer survival
Vitamin D, the "sunshine vitamin," may be helpful for people diagnosed with colon cancer, says Charles Fuchs, MD, MPH , director of Yale Cancer Center. A small clinical trial, called the "Sunshine Trial," found the odds of dying from colon cancer were lower for those with high levels of vitamin D in their bloodstream than for those whose blood contained lower levels.

Health - Pharmacology - 10.06.2019
Improving breast cancer treatment
Millions of patients with incurable breast cancer could benefit from Welsh-led research which shows it is possible to control the cancer for twice as long by combing an investigational therapy with standard treatment. Oestrogen receptive positive breast cancer can be treated by drugs, such as fulvestrant, that interfere with the action of oestrogen.

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