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Pharmacology



Results 121 - 140 of 165.


Pharmacology - Chemistry - 11.02.2019
Machine learning algorithm helps in the search for new drugs
Researchers have designed a machine learning algorithm for drug discovery which has been shown to be twice as efficient as the industry standard, which could accelerate the process of developing new treatments for disease.  The ability to fish out four active molecules from six million is like finding a needle in a haystack Alpha Lee The researchers, led by the University of Cambridge, used their algorithm to identify four new molecules that activate a protein which is thought to be relevant for symptoms of Alzheimer's disease and schizophrenia.

Life Sciences - Pharmacology - 11.02.2019
Cell component breakdown suggests possible treatment for multiple neural disorders
UW-Madison research published today (Feb. 11, 2019) reveals how one mutation causes fragile X, the most common inherited intellectual disability. "Fragile X syndrome has been studied as a model of intellectual disability because in theory it's comparatively simple," says senior author Xinyu Zhao, a professor of neuroscience in the Waisman Center at the University of Wisconsin-Madison.

Health - Pharmacology - 11.02.2019
For recurrent glioblastoma, immunotherapy before surgery appears to help more than afterward
For recurrent glioblastoma, immunotherapy before surgery appears to help more than afterward
A UCLA-led study suggests that for people with recurrent glioblastoma, administering an immunotherapy drug before surgery is more effective than using the drug afterward. In recent years, immunotherapy drugs, which harness the body's immune system to destroy cancer cells, have been shown to be helpful in treating people with advanced or metastatic cancer.

Pharmacology - Health - 08.02.2019
Fluconazole Makes Fungi Sexually Active
Fluconazole Makes Fungi Sexually Active
Under the influence of the drug fluconazole, the fungus Candida albicans can change its mode of reproduction and thus become even more resistant. Scientists at the University of Würzburg report this in the journal mBio. The yeast Candida albicans occurs in most healthy people as a harmless colonizer in the digestive tract.

Health - Pharmacology - 08.02.2019
Drug-resistant tuberculosis: high mortality rate due to inaccurate tests
Drug-resistant tuberculosis: high mortality rate due to inaccurate tests
Inaccurate tests carried out on tuberculosis patients in developing countries often fail to reliably detect resistance to drugs, leading to incorrect treatment and a higher mortality rate. These are the results of study by an international group of researchers led by a team at the University of Bern published today.

Pharmacology - Health - 07.02.2019
New pill can deliver insulin
New pill can deliver insulin
Capsule that releases insulin in the stomach could replace injections for patients with type 2 diabetes. About the size of a blueberry, the capsule contains a small needle made of compressed insulin, which is injected after the capsule reaches the stomach. In tests in animals, the researchers showed that they could deliver enough insulin to lower blood sugar to levels comparable to those produced by injections given through skin.

Health - Pharmacology - 06.02.2019
Researchers awarded £1.3 million to fight prostate cancer
Researchers awarded £1.3 million to fight prostate cancer
Prostate Cancer UK has awarded researchers over £1.3 million for three projects that could lead to new treatments for the disease. The Research Innovation Awards is a prestigious scheme aimed at funding the most impactful research in prostate cancer. The number of prostate cancer cases is increasing in the UK - the condition kills over 11,000 men every year - and research is desperately needed to find new ways of tackling the disease.

Health - Pharmacology - 05.02.2019
Even psychological placebos have an effect
Even psychological placebos have an effect
Placebo effects do not only occur in medical treatment - placebos can also work when psychological effects are attributed to them. Psychologists from the University of Basel reported these findings in the journal Scientific Reports, based on three studies with over 400 participants. Psychotherapy and placebos are both psychological interventions that not only have comparable effects, but that are also based on very similar mechanisms.

Life Sciences - Pharmacology - 05.02.2019
A better way to measure cell survival
A better way to measure cell survival
New test rapidly evaluates the effect of drugs and potentially toxic compounds on cells. Measuring the toxic effects of chemical compounds on different types of cells is critical for developing cancer drugs, which must be able to kill their target cells. Analyzing cell survival is also an important task in fields such as environmental regulation, to test industrial and agricultural chemicals for possible harmful effects on healthy cells.

Health - Pharmacology - 05.02.2019
Hope on the horizon
There are currently an estimated 100,000 people in the United States who are living with sickle cell disease-a debilitating and life-threatening blood condition that predominantly affects people of African and Mediterrane an descent, and Hispanic-Americans from Central and South America. For years, those who suffer from the disease have been treated with temporary solutions, but now advances in gene therapy have opened doors to a possible cure.

Health - Pharmacology - 01.02.2019
New vaccine for malaria developed at IME could be more effective
Researchers at the Institute for Molecular Engineering at the University of Chicago have developed an innovative new system for delivering a malaria vaccine that shows promise in its effectiveness. By developing a vaccine that targets specific cells in the immune system, they have seen a much greater immune and antibody response to the vaccine.

Chemistry - Pharmacology - 01.02.2019
Intuition and failure are valuable ingredients in chemistry
Intuition and failure are valuable ingredients in chemistry
When researchers make a new discovery, they tend to only publish the results of their successful experiments. But just as informative are all the experiments that didn't work - the failed trials and incorrect hypotheses, which can offer important information. A team of EPFL chemists has developed a methodology for collecting those lessons and, crucially, sharing them with other researchers.

Health - Pharmacology - 31.01.2019
Statin therapy reduces cardiovascular disease risk in older people
Statin therapy reduces major vascular events, such as heart attacks and strokes, in people of all ages, including those over the age of 75, according to a new study published in The Lancet. The study assessed the effects of statins in nearly 187,000 people who had taken part in 28 large clinical trials.

Life Sciences - Pharmacology - 30.01.2019
This eel-like animal can regrow a severed spinal cord-twice
Spontaneous recovery from spinal cord injury is almost unheard of in humans and other mammals, but many vertebrates fare better. The eel-like lamprey, for instance, can fully regenerate its spinal cord even after it's been severed-within 3 months the lamprey is swimming, burrowing and flipping around again, as if nothing had happened.

Life Sciences - Pharmacology - 30.01.2019
New Findings About Anti-Malaria Drug
New Findings About Anti-Malaria Drug
01/30/2019 Researchers at the Rudolf Virchow Center of the University of Würzburg have unveiled the molecular effectiveness of artemisinins. The findings could lead to drugs for diseases such as Alzheimer's, schizophrenia and epilepsy. Artemisinin is derived from the leaves and flowers of the annual mugwort (Artemisia annua) and has been used in traditional Chinese medicine for centuries.

Pharmacology - Health - 29.01.2019
New target for gastric cancer therapies
New target for gastric cancer therapies
Cardiff University researchers have uncovered new information about the underlying mechanisms for gastric cancer, providing hope of potential new therapies in the future. The team, at the University's European Cancer Stem Cell Research Institute, found they could stop gastric cells dividing and growing by deleting a particular cell-surface receptor implicated in the function of stem cells.

Health - Pharmacology - 28.01.2019
Hepatitis C programmes could save 1.5 million deaths by 2030
Hepatitis C programmes could save 1.5 million deaths by 2030
Imperial scientists have published the first global estimates to determine the impact of improved prevention, diagnosis and treatment for hepatitis C. A comprehensive package of prevention, screening, and treatment interventions could avert 15.1 million new hepatitis C infections and 1.5 million cirrhosis and liver cancer deaths globally by 2030 - equal to an 81% reduction in incidence and a 61% reduction in deaths compared with 2015, according to the first study to model hepatitis C interventions globally published in The Lancet.

Life Sciences - Pharmacology - 28.01.2019
"Stop, do not eat fat anymore!"
During fat ingestion , if everything works in our body, an enzyme from the intestine transmits to the brain (through the production of molecules) the message "stop, I am not hungry anymore" . This gut-brain axis maintains a balanced food intake. Researchers from the UCLouvain were able to target this enzyme.

Health - Pharmacology - 28.01.2019
Phone or video call therapy improves health anxiety and saves money
A new study by mental health experts has found that easy-access, remotely-delivered psychological treatment can significantly reduce extreme health anxiety in people who repeatedly go to the doctor, or hospital emergency departments.

Pharmacology - Health - 28.01.2019
Helping kids manage side effects of allergy treatments
Stanford psychologists find that a positive mindset can make children less anxious about mild but uncomfortable symptoms that arise during treatment for peanut allergies. For children undergoing immunotherapy - a promising treatment for peanut allergies - uncomfortable side effects can induce anxiety, perhaps to the point of skipping doses or dropping treatment entirely.