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Health - Pharmacology - 15.04.2019
Birmingham experts join Indian medics to counter surgical infection threat
University of Birmingham experts joined medical professionals in India to set up an innovative research centre that will help to improve care for surgical patients. Among the first studies to be launched would be a surgical trial to look at interventions to reduce the - often devastating - impact of post-surgical infection (FALCON); as well as a study to evaluate access to healthcare for patients requiring surgery.

Health - Pharmacology - 15.04.2019
Malaria and the doctor who changed the rules of treatment
Malaria and the doctor who changed the rules of treatment
The people of Burma, now Myanmar, were being devastated by conflict and drug resistant malaria, when alumna Rose McGready arrived. It was a temporary work placement that became much more than she expected. When Professor Rose McGready (MBBS '90) arrived on the Thai/Myanmar border in 1994, it had been a volatile and dangerous part of the world for many years.

Pharmacology - Health - 12.04.2019
Clinical trials: Important feedback on new cancer treatments from thousands of patients remains unpublished
Macmillan Cancer Support and the University of Birmingham urge researchers to use newly developed international guidelines so that all key data is published and patients are fully informed about how cancer drugs affect quality of life. Important feedback about quality of life from up to 49,000 cancer patients who took part in UK-led clinical trials from 2000-2014 remains unpublished, according to a new study led by researchers at the University of Birmingham and funded by Macmillan Cancer Support.

Health - Pharmacology - 11.04.2019
Bristol part of ¤20.8M study to drive drug discovery for atopic dermatitis and psoriasis
Bristol part of ¤20.8M study to drive drug discovery for atopic dermatitis and psoriasis
The lives of patients affected by atopic dermatitis and psoriasis could be improved thanks to the start of an EU-funded research project BIOMAP (Biomarkers in Atopic Dermatitis and Psoriasis). The five-year project will address key unmet needs in treating these common inflammatory skin conditions by analysing data from more than 50 000 patients to improve disease understanding, patient care and future therapies.

Health - Pharmacology - 11.04.2019
The way people walk says a lot about how healthy they are
The way people walk says a lot about how healthy they are
Gait characteristics are sometimes regarded as the sixth vital sign in humans. They serve as a valuable indicator of a person's health, particularly in older adults - so why not measure them? A team of EPFL researchers is taking part in a major European project to design a device that can assess a person's gait more accurately.

Pharmacology - Life Sciences - 10.04.2019
Active lifestyles may help nerves to heal after spinal injuries
Active lifestyles may help nerves to heal after spinal injuries
Leading an active lifestyle may increase the likelihood of damaged nerves regenerating after a spinal cord injury. The early-stage findings , published in the journal Science Translational Medicine , come from studies in mice and rats with spinal cord injuries, in which scientists uncovered a mechanism for nerve fibres repairing after they had been damaged.

Health - Pharmacology - 09.04.2019
Antibiotic resistance across Wisconsin revealed by new maps
When a patient arrives at a hospital with an infection, her doctor must decide which antibiotic might have the best chance of curing her - no easy feat when disease-causing pathogens are increasingly resistant to multiple antibiotics. For that reason, hospitals often track the antibiotic resistance profiles of infectious microbes that they isolate from sick patients, which provide information on the most and least effective drugs.

Pharmacology - Health - 05.04.2019
New target for development of drugs to fight viruses
Researchers at Cardiff University have discovered that a molecule responsible for guiding virus-killing T-cells to the site of infection is also responsible for rapidly increasing T-cell numbers to fight infection, making it an important new target for the development of more effective drugs to treat both viruses and cancers.

Life Sciences - Pharmacology - 04.04.2019
Scientists fine-tune signalling pathways to tweak responses to stimuli in yeast
Scientists fine-tune signalling pathways to tweak responses to stimuli in yeast
Imperial academics have streamlined a signalling pathway in yeast to understand how cell sensing can be tuned by changing protein levels. The research , published in Cell , could eventually help us understand drug side effects in humans, and has immediate implications for biotechnology research. G-protein coupled receptors (GPCRs) are proteins which let cells detect chemical substances like hormones, poisons, and drugs in their environment.

Life Sciences - Pharmacology - 04.04.2019
How do muscle and tendon connections last a lifetime?
How do muscle and tendon connections last a lifetime?
Muscles are connected to tendons to power animal movements such as running, swimming or flying. Forces are produced by contractile chains of the proteins actin and myosin, which are pulling on muscle-tendon connections called attachments. During animal development, these muscle-tendon attachments must be established such that they resist high mechanical forces for the entire life of the animal.

Innovation / Technology - Pharmacology - 02.04.2019
Nestlé Health Science set to use anti-aging compound
Amazentis, an EPFL spin-off based in Innovation Park, announced today that it is entering into a strategic partnership with Nestlé Health Science. The startup plans to develop products based on urolithin A, a promising anti-aging compound. The Fountain of Youth is still the stuff of legend, but the anti-aging compound urolithin A is now one step closer to the market.

Health - Pharmacology - 28.03.2019
Breast cancer: the promises of old recipes
Breast cancer: the promises of old recipes
Researchers from UNIGE and UNIL demonstrate the efficacy of a well-known antibiotic in treating a particularly fatal form of breast cancer, offering hope for targeted therapy. Of the three major subtypes of breast cancer, the «triple negative» is the most lethal: half of all breast cancer deaths are attributed to it, whereas it accounts for only about 15% of incidences of breast cancer.

Health - Pharmacology - 27.03.2019
Heating up tumors could make CAR’T therapy more effective
FINDINGS A preclinical study led by scientists at the UCLA Jonsson Comprehensive Cancer Center suggests that heating solid tumors during CAR T-cell therapy can enhance the treatment's success. The researchers found that when a heating technique called photothermal ablation was combined with the infusion of CAR T cells, it suppressed melanoma tumor growth for up to 20 days in mice.

Pharmacology - Life Sciences - 26.03.2019
New 'pulsing' ultrasound technique improves drug delivery to brains of mice
New ’pulsing’ ultrasound technique improves drug delivery to brains of mice
Using rapid short-pulse sequences of ultrasound helps drugs reach the brains of mice, according to new Imperial College London research. Scientists currently use long-wave pulses of ultrasound to deliver drugs, which can cause side effects. Now, these new findings from Imperial on shorter-wave pulses could change how drugs are used to help patients of Alzheimer's and other neurological diseases.

Pharmacology - Health - 23.03.2019
Levothyroxine treatment in women with thyroid antibodies may not increase live birth rate
Treating women with thyroid antibodies but a normal thyroid function with a medicine called Levothyroxine does not make them more likely to deliver a live baby, new research led by the University of Birmingham suggests. The research, which was led by researchers from the Institute of Metabolism and Systems Research , Birmingham Clinical Trials Unit, the Institute of Applied Health Research, and Tommy's Centre for Miscarriage Research at the University of Birmingham, was published today in New England Journal of Medicine .

Pharmacology - Life Sciences - 22.03.2019
How new ketamine drug helps with depression
On March 5, the Food and Drug Administration (FDA) approved the first truly new medication for major depression in decades. The drug is a nasal spray called esketamine, derived from ketamine-an anesthetic that has made waves for its surprising antidepressant effect.   Because treatment with esketamine might be so helpful to patients with treatment-resistant depression (meaning standard treatments had not helped them), the FDA expedited the approval process to make it more quickly available.

Chemistry - Pharmacology - 22.03.2019
Inert Nitrogen Forced to React with Itself
Inert Nitrogen Forced to React with Itself
03/22/2019 Direct coupling of two molecules of nitrogen: chemists from Würzburg and Frankfurt have achieved what was thought to be impossible. This new reaction is reported and opens new possibilities for one of the most inert molecules on earth. Constituting over 78 % of the air we breathe, nitrogen is the element found the most often in its pure form on earth.

Health - Pharmacology - 22.03.2019
Bringing a new generation of drugs to patients
Bringing a new generation of drugs to patients
Cardiff University is stepping up the development of new drugs for mental health and central nervous system conditions, with the launch of the Medicines Discovery Institute. Focusing on areas of unmet clinical need, the new institute will develop novel medications to improve the lives of people across the world.

Health - Pharmacology - 21.03.2019
New class of membranes shown to regenerate tissue and bone, viable solution for periodontitis
New class of membranes shown to regenerate tissue and bone, viable solution for periodontitis
Periodontitis affects nearly half of Americans ages 30 and older, and in its advanced stages, it could lead to early tooth loss or worse. Recent studies have shown that periodontitis could also increase risk of heart disease and Alzheimer's disease. A team of UCLA researchers has developed methods that may lead to more effective and reliable therapy for periodontal disease — ones that promote gum tissue and bone regeneration with biological and mechanical features that can be adjusted based on treatment needs.

Chemistry - Pharmacology - 21.03.2019
With a 'hello,' Microsoft and UW demonstrate first fully automated DNA data storage
With a ’hello,’ Microsoft and UW demonstrate first fully automated DNA data storage
Researchers from the University of Washington and Microsoft have demonstrated the first fully automated system to store and retrieve data in manufactured DNA - a key step in moving the technology out of the research lab and into commercial data centers. In a simple proof-of-concept test, the team successfully encoded the word "hello" in snippets of fabricated DNA and converted it back to digital data using a fully automated end-to-end system, which is described in a new paper published March 21 in Nature Scientific Reports.
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