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Pharmacology - Business / Economics - 02.08.2019
Family influence key in spread of opioid use
New research from two UC Berkeley professors shows that exposure to opioids in the home can double the chances someone else in the home gets a prescription to the addictive painkillers. (Flickr photo by Michael Chen, shared under CC 2.0) Introducing an opioid painkiller into a home can double the chances someone else living in the home seeks out the addictive drugs on his or her own, according to a new paper from two UC Berkeley researchers.

Health - Pharmacology - 02.08.2019
Larger blood transfusions could halve deaths of children with severe anaemia
Giving larger volumes of blood transfusions to children with severe anaemia in sub-Saharan Africa could halve the number of deaths. This is the finding of new research from a clinical trial co-led by Imperial College London and UCL. Results from the TRACT trial , published today in the New England Journal of Medicine and funded by the Medical Research Council (MRC) , show that children with complicated severe anaemia who do not have a fever require larger volumes of blood transfusions than current World Health Organisation (WHO) guidelines.

Health - Pharmacology - 01.08.2019
Can a combination immune therapy reduce genital herpes outbreaks?
Can a combination immune therapy reduce genital herpes outbreaks?
Yale investigators have shown that the combination of a vaccine and a medicated cream is a promising strategy to dramatically reduce the recurrence of genital herpes. Their study, co-led by researchers at the University of Pennsylvania and University of Cincinnati Children's Hospital Medical Center, was published in the journal npj Vaccines.

Health - Pharmacology - 01.08.2019
Identifies new cell type that triggers deadly allergic reactions
For millions of Americans, contact with certain foods can cause anaphylaxis, a life-threatening allergic reaction. A new study has uncovered a previously unknown cell type that promotes the reaction and could be used to identify individuals who are most at risk. The study, co-led by researchers at Yale School of Medicine and The Jackson Laboratory for Genomic Medicine, was published online in Science.

Health - Pharmacology - 01.08.2019
New ’don’t eat me’ signal may provide basis for cancer therapies
Cancer cells are known to protect themselves using proteins that tell immune cells not to attack them. Stanford researchers have discovered a new "don't eat me" signal, and blocking it may make cancer cells vulnerable to attack by the immune system. Researchers at the Stanford University School of Medicine have discovered a new signal that cancers seem to use to evade detection and destruction by the immune system. The scientists have shown that blocking this signal in mice implanted with human cancers allows immune cells to attack the cancers.

Health - Pharmacology - 01.08.2019
Endometrial diseases can be imitated in a lab dish
Biomedical researchers at KU Leuven have found a new way to study endometrial diseases such as endometriosis and cancer. They were able to grow three-dimensional cell structures from diseased tissue of patients. The biobank can be used to unravel the disorders and test drugs. Diseases of the endometrium are an important cause of infertility.

Pharmacology - 01.08.2019
Model predicts cognitive decline due to Alzheimer's, up to two years out
Model predicts cognitive decline due to Alzheimer’s, up to two years out
Researchers hope the system can zero in on the right patients to enroll in clinical trials, to speed discovery of drug treatments. MIT researchers have developed an AI system that can predict Alzheimer's risk by forecasting how patients will perform on a test measuring cognitive decline up to two years in advance, reports Casey Ross for STAT .

Pharmacology - 31.07.2019
Hidden chemistry in flowers shown to kill cancer cells
Researchers at the University of Birmingham have shown that it's possible to produce a compound with anti-cancer properties directly from feverfew - a common flowering garden plant. The team was able to extract the compound from the flowers and modify it so it could be used to kill chronic lymphocytic leukaemia (CLL) cells in the laboratory.

Pharmacology - 31.07.2019
How do you get up from a chair?
Joe Sanz was outfited with 16 special sensors and hooked up to a small device called the Gymaware Powertool, which measures lower body power and velocity as one gets up and down from a chair. Photo: Barbara Gutierrez/University of Miami Joe Sanz was outfited with 16 special sensors and hooked up to a small device called the Gymaware Powertool, which measures lower body power and velocity as one gets up and down from a chair.

Health - Pharmacology - 30.07.2019
$1.1m to tackle Crohn’s disease in children and adults with a novel diet
The University of Glasgow has received $1.1 million from The Leona M. and Harry B. Helmsley Charitable Trust to evaluate the effectiveness of a novel, regular solid food-based diet to improve clinical outcomes in adults and children with active Crohn's disease. The grant was awarded to further build on recent research led by Dr. Konstantinos Gerasimidis and his team looking into a practical alternative to the commonly used liquid-only diet treatment for Crohn's disease, also known as exclusive enteral nutrition (EEN).

Pharmacology - Health - 29.07.2019
Explainer: What is Ligandrol and how does it work?
Associate Professor Nial Wheate from the School of Pharmacy comments on the history of Ligandrol, how it works and news this week about the drug. Australian freestyle swimmer Shayna Jack tested positive to the banned substance Ligandrol in late June , before competing at the world swimming championships in South Korea this month.

Pharmacology - Health - 27.07.2019
Global scheme to cut price of expensive hepatitis drugs boosts treatment rate
An initiative to improve access to high-cost hepatitis C treatments in poorer countries has resulted in more people being treated for the disease. This is the finding of a new study from Imperial College London , published in the journal The Lancet Global Health. The global scheme, which allows the patented drugs to be manufactured under so-called voluntary licences, aims to ensure high cost medications are affordable to lower income nations.

Health - Pharmacology - 26.07.2019
Electrodes in remaining arms give amputees better control of prosthetics
Electrodes in remaining arms give amputees better control of prosthetics
Vienna and Imperial College London scientists implanted electrodes in amputees' stumps for better prosthetic control - with promising results. This early-stage research , on three men with above-elbow arm amputations, involved relocating nerves in their remaining arms before implanting wirelessly chargeable electrodes and fitting new prosthetic arms.

Pharmacology - Health - 22.07.2019
Serious falls are a health risk for adults under 65
Adults who take several prescription medications are more likely to experience serious falls, say Yale researchers and their co-authors in a new study. This heightened risk can affect middle-aged individuals - a population not typically viewed as vulnerable to debilitating or fatal falls, the researchers said.

Health - Pharmacology - 18.07.2019
Two-thirds of Global South hypertension sufferers missing treatment - study
Healthcare in lowand middle-income countries is poorly prepared for the increasing number of people with high blood pressure, with more than two-thirds of people affected going without treatment - a new study reveals. Researchers studied health data for one million people in the Global South, discovering that less than half of those affected are diagnosed with high blood pressure or hypertension.

Health - Pharmacology - 18.07.2019
Omega-6 fatty acid could help prevent heart disease
An omega-6 polyunsaturated fatty acid has the potential to help fight heart disease, finds a new study by researchers at Cardiff University in collaboration with Ben-Gurion University of the Negev. With funding from the British Heart Foundation, the team found that dihomo-gamma-linolenic acid (DGLA), an omega-6 polyunsaturated fatty acid, could halt the progression of atherosclerosis - one of the leading causes of heart disease.

Life Sciences - Pharmacology - 18.07.2019
New prebiotics: benefits without the downsides?
New prebiotics: benefits without the downsides?
Prebiotics are currently a preferred treatment for certain metabolic disorders, as they can restore the balance of dysfunctional gut microbiota, and improve the body's metabolism. However, these substances have to be used at high doses, which can result in patients experiencing bloating and flatulence.

Health - Pharmacology - 16.07.2019
Bacterial defence construction revealed in step forward for new antibiotics
Bacterial defence construction revealed in step forward for new antibiotics
A crucial step in the way bacteria construct their defences has been revealed by an international team, including a University of Queensland researcher. Institute for Molecular Bioscience 's researcher Professor Ian Henderson said the finding had opened up a new pathway for designing improved antibiotics.

Health - Pharmacology - 15.07.2019
Homeless people are denied basic health care
A study led by the University of Birmingham has painted a shaming picture of neglect and discrimination shown towards the homeless when accessing UK health services. Researchers interviewed 22 homeless people aged over 18 at three Midland homeless shelters in order to gauge their experience of accessing NHS services following anecdotal reports that the homeless were being denied access and faced negative experiences.

Pharmacology - Health - 15.07.2019
Science of microdosing psychedelics ’remains patchy and anecdotal’, says review
The practice of taking small, regular doses of psychedelic drugs to enhance mood, creativity, or productivity lacks robust scientific evidence. The process, called microdosing, has been lauded by some, with high profile proponents in Silicon Valley. But to date, scientific evidence to support or even fully explore claims of the benefits and safety, has been lacking.
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