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Health - Pharmacology - 06.03.2019
New Hepatitis C cases down by almost 70 per cent in HIV positive men in London
New cases of hepatitis C amongst HIV positive men in London have fallen by nearly 70 per cent in recent years. The new analysis of data from three clinics in London found 256 men were diagnosed between 2013-2018. New infections peaked at 17 for every 1000 people studied in 2015 and fell to six by 2018.

Pharmacology - Health - 05.03.2019
HIV remission achieved in second patient
A second person has experienced sustained remission from HIV-1 after ceasing treatment, reports a paper led by UCL and Imperial College London. The case report comes ten years after the first such case, known as the ‘Berlin Patient.' Both patients were treated with stem cell transplants from donors carrying a genetic mutation that prevents expression of an HIV receptor CCR5.

Pharmacology - Health - 05.03.2019
Tissue model reveals how RNA will act on the liver
Tissue model reveals how RNA will act on the liver
Studies could speed the development of new treatments for liver disease. Novel therapies based on a process known as RNA interference (RNAi) hold great promise for treating a variety of diseases by blocking specific genes in a patient's cells. Many of the earliest RNAi treatments have focused on diseases of the liver, because RNA-carrying particles tend to accumulate in that organ.

Life Sciences - Pharmacology - 05.03.2019
Could genetic breakthrough finally help take the sting out of mouth ulcers?
A large breakthrough has been made in the genetic understanding of mouth ulcers which could provide potential for a new drug to prevent or heal the painful lesions. Mouth ulcers affect up to 25 per cent of young adults and a higher proportion of children. Previous research has shown that mouth ulcers are partially heritable, but until now there has been little evidence linking specific genes or genomic regions to mouth ulcers.

Pharmacology - Health - 05.03.2019
HIV remission achieved in second patient
HIV remission achieved in second patient
A second person has experienced sustained remission from HIV-1 after ceasing treatment, according to a study published today in Nature.

Health - Pharmacology - 05.03.2019
’Test and Treat’ reduces new HIV infections by a third in African communities
Results from largest ever HIV prevention trial suggest strategy could make a significant contribution to controlling epidemic New HIV infections in southern Africa could be reduced substantially by offering entire communities voluntary HIV testing, and immediately referring those who test positive for HIV treatment in line with local guidelines, according to new research presented at the Conference on Retroviruses and Opportunistic Infections (CROI) in Seattle, USA today.

Pharmacology - Chemistry - 04.03.2019
When changing one atom makes molecules better
Chemists in Vienna find a method to replace hydrogen with fluorine in organic molecules The development and improvement of pharmaceuticals plays the central role in the ongoing battle against human disease. Organic synthesis is the field that enables these developments as it offers the toolbox to diversify chemical structures.

Pharmacology - Health - 04.03.2019
’Game changer’ in treatment of chronic lymphocytic leukaemia
The first test to quickly and accurately predict how people will respond to standard treatment for the most common type of leukaemia has been developed at Cardiff University. The technology could guide doctors' decisions on which drugs to give to patients. The Cardiff researchers say that the test could now be a ‘game changer' in the treatment of chronic lymphocytic leukaemia (CLL).

Health - Pharmacology - 04.03.2019
Novartis data confirm rapid response and high efficacy of Cosentyx in psoriasis patients for first time in China
Phase III study shows close to 9/10 patients who received Cosentyx 300mg achieved clear or almost clear skin during the first 16 weeks of treatment (87%), with rapid onset of relief seen as early as week 3   Results strengthen unique position of Cosentyx as a rapid and long-lasting complete treatment of psoriatic disease, with over 200,000 patients treated worldwide   Data is being presented at the 2019 American Academy of Dermatology (AAD) Annu

Health - Pharmacology - 04.03.2019
Benefits of informal health expertise
A new Stanford study tackles the issue of health inequality and examines the benefits of having access to informal health expertise by having a medical professional in the family. A helpful reminder - something as simple as "Are you taking your medications?" - could conceivably prolong a life. A new study shows that having a health professional in the family is good for your health.

Pharmacology - Health - 28.02.2019
Majority of bipolar patients missing out on the most effective treatments
A quarter of patients with bipolar disorder in Scotland are being prescribed medication that could make symptoms worse and cause serious episodes of mania. The research, led by the University of Glasgow and published today in the British Journal of Psychiatry , reveals that many patients with bipolar disorder in Scotland are on combinations of medication treatments that are out of line with recommended clinical guidelines.

Pharmacology - Health - 27.02.2019
Antibiotic prescribing in primary care
New research on when and how GPs should prescribe antibiotics for common infections is published in The BMJ today [Wednesday 27 February] and is accompanied by an editorial response from the University of Bristol's Centre for Academic Primary Care (CAPC). Primary care is responsible for around 80 per cent of all health service antibiotic prescribing in the UK, with rates likely to be similar worldwide.

Pharmacology - Health - 27.02.2019
Early use of antibiotics in elderly patients associated with reduced sepsis risk
Prescribing antibiotics immediately for elderly patients with urinary tract infections is linked with a reduced risk of sepsis and death. These are the latest findings from researchers at Imperial College London and Public Health England , published in the BMJ.

Health - Pharmacology - 27.02.2019
Researchers identify potential mechanism to control nonalcoholic fatty liver disease
Researchers identify potential mechanism to control nonalcoholic fatty liver disease
FINDINGS In a comprehensive, nine-year-long study in mice, researchers profiled more than 300 liver and plasma lipid species and more than 5,000 liver proteins. The combined data helped researchers to identify new mechanisms that control the metabolism of lipids (molecules that include fat) and to discover a protein that regulates lipids.

Pharmacology - Innovation / Technology - 27.02.2019
CEA-Leti Breakthrough Opens Path To New Vaccine for HIV using Lipid-Nanoparticle-Delivery Technology
CEA-Leti Breakthrough Opens Path To New Vaccine for HIV using Lipid-Nanoparticle-Delivery Technology
Lipidots Platform Strengthens Immune Response to Protein That Is Key to HIV Vaccine; Results Presented in Nature Publishing Group's npj Vaccines GRENOBLE, France - Feb. 27, 2019 - Leti, a research institute of CEA Tech, in collaboration with CEA's Fundamental Research Division , has developed a new vaccine approach for HIV based on engineered lipid nanoparticles that deliver p24 - a viral protein that is key to an HIV vaccine- and optimize the CpG adjuvant's effect.

Health - Pharmacology - 26.02.2019
Steroid treatment for premature babies linked to low birth weight
Steroid injections given to mothers at risk of giving birth prematurely are linked to babies being born with lower body weights. In a study of more than a quarter of a million births, researchers found an association between steroid treatment - used to help an unborn baby's lungs develop - and reduced birth weight.

Life Sciences - Pharmacology - 26.02.2019
Improved outlook for people of African descent with treatment-resistant schizophrenia
A study led by researchers at Cardiff University means that more people of African descent who have treatment-resistant schizophrenia could be safely given the drug best proven to manage their symptoms. The team identified a genetic and benign cause in people of African descent for lower neutrophil levels: a condition that can also be a rare and potentially life-threatening side-effect of the only licensed medication for treatment-resistant schizophrenia.

Health - Pharmacology - 26.02.2019
Why Laron dwarfs don't get diabetes
Why Laron dwarfs don’t get diabetes
University of Queensland researchers have discovered a hidden metabolic advantage that prevents people with a specific type of dwarfism from developing type 2 diabetes or cancer. UQ Diamantina Institute researcher Dr Yash Chhabra said the findings could pave the way for new diabetes treatments for all.

Health - Pharmacology - 25.02.2019
Opioid epidemic makes eastern inroads and targets African-Americans
Opioids overdoses now kill more Americans than  car accidents or guns , with more than 350,000 Americans having succumbed to the painkillers since 2000. "The opioid misuse and overdose crisis touches everyone in the United States," Health and Human Services Secretary Alex Azar said in this recent  report.

Health - Pharmacology - 25.02.2019
Surgery for uncomplicated appendicitis in adults is effective and safe
Surgery for uncomplicated appendicitis in adults is effective and safe
FINDINGS Researchers found that more than 97 percent of the surgeries for appendicitis were laparoscopic, or minimally invasive, and most patients were discharged the same day or the next day. Only 3 percent of the procedures resulted in complications. Rates of unnecessary surgery — removing a “normal” appendix — were low (less than 4 percent), but were much higher in people without imaging studies before their operation (nearly 20 percent).
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