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Pharmacology



Results 61 - 80 of 219.


Pharmacology - Health - 12.06.2019
New vulnerability found in viruses may help develop cure for the common cold
A team of researchers led by KU Leuven virologist Johan Neyts have discovered a new feature of so-called picornaviruses that may allow for the development of new antiviral medications for the common cold, polio, and other illnesses. Picornaviruses include rhinoviruses and enteroviruses. Rhinoviruses cause millions of cases of upper respiratory infections ("colds") yearly and contribute to asthma, and enteroviruses are responsible for millions of infections including cases such as meningitis, encephalitis and polio.

Health - Pharmacology - 12.06.2019
Checkmate for hepatitis B viruses in the liver
Checkmate for hepatitis B viruses in the liver
Infections with HBV are a global health problem. According to the World Health Organisation (WHO), more than 260 million people worldwide are chronically infected with the virus. Vaccination prevents new HBV infections, but for people who are chronic carriers of the virus, a cure has not yet been found.

Pharmacology - Chemistry - 11.06.2019
Learning from Nature's Bounty: New Libraries for Drug discovery
Learning from Nature’s Bounty: New Libraries for Drug discovery
Natural products, or their close derivatives, make some of our most potent medicines, among which macrocycles with their large carbon-rich ring systems are one class. The size and complexity of macrocycles has made it difficult to emulate and build on Nature's success in the laboratory.

Health - Pharmacology - 11.06.2019
Peptides that mimic ’good cholesterol’ reverse inflammatory bowel disease in mice
FINDINGS Peptides that mimic the function of HDL cholesterol, which has been dubbed “good cholesterol,” can treat the underlying inflammation associated with inflammatory bowel disease, or IBD, according to new research in mice. The same work revealed new details on how IBD can develop and what other types of drugs may work to treat the disease.

Health - Pharmacology - 11.06.2019
Are pharma payments to nurses impacting your healthcare?
Are pharma payments to nurses impacting your healthcare?
New analysis reveals pharmaceutical industry payments to Australian non-prescribing healthcare professionals such as nurses and pharmacists are substantial, raising questions around influence and a call for greater transparency. There's growing awareness that payments by the pharmaceutical industry to doctors - including the provision of even a modest meal at company-hosted events - are associated with poorer quality prescribing behaviour and increased healthcare costs.

Pharmacology - Chemistry - 10.06.2019
Healing compounds in scorpion venom
Stanford chemists have identified and synthesized two new healing compounds in scorpion venom that are effective at killing staph and tuberculosis bacteria. A scorpion native to Eastern Mexico may have more than just toxin in its sting. Researchers at Stanford University and in Mexico have found that the venom also contains two color-changing compounds that could help fight bacterial infections.

Health - Pharmacology - 10.06.2019
Vitamin D and colorectal cancer survival
Vitamin D, the "sunshine vitamin," may be helpful for people diagnosed with colon cancer, says Charles Fuchs, MD, MPH , director of Yale Cancer Center. A small clinical trial, called the "Sunshine Trial," found the odds of dying from colon cancer were lower for those with high levels of vitamin D in their bloodstream than for those whose blood contained lower levels.

Health - Pharmacology - 10.06.2019
Improving breast cancer treatment
Millions of patients with incurable breast cancer could benefit from Welsh-led research which shows it is possible to control the cancer for twice as long by combing an investigational therapy with standard treatment. Oestrogen receptive positive breast cancer can be treated by drugs, such as fulvestrant, that interfere with the action of oestrogen.

Health - Pharmacology - 09.06.2019
Immunotherapy delays type 1 diabetes in people at high risk
A drug that targets the immune system can delay the onset of type 1 diabetes in people at high risk of developing the disease, said a Yale investigator who led the National Institutes of Health-funded Diabetes TrialNet study. The research is the first to show that the progression of type 1 diabetes can be slowed by two or more years with immunotherapy.

Pharmacology - Health - 06.06.2019
Three-drug combination helps curb the growth of deadly type of skin cancer
A UCLA-led research team has pinpointed a three-drug combination that could prove to be an effective new therapy for people with a specific type of advanced melanoma. The approach shows promise for extending the lives of people with a type of melanoma that contains a potent gene mutation, BRAF V600E.

Health - Pharmacology - 05.06.2019
TAVR is helping people avoid open heart surgery
There was big news on Twitter this spring. The Rolling Stones tweeted that Mick Jagger, who is 75 and had been diagnosed with a heart problem, underwent a procedure and was expected to be back on the stage as soon as possible. His timing was spot on. Jagger had been diagnosed with aortic stenosis, a narrowing of his aortic valve.

Pharmacology - Health - 04.06.2019
Beta blockers reduce stress-induced irregular heart rhythm
Taking beta blockers - medications that reduce blood pressure and treat many heart conditions - can blunt the negative effects of stress and anger on people with a history of atrial fibrillation, or irregular heart rhythm, said Yale researchers. This strategy could potentially improve quality of life for many of the two million Americans with the condition, according to a new study.

Pharmacology - Health - 03.06.2019
Role of bacteria in drug response
Yale researchers identified human gut microbes that metabolize over 150 therapeutic drugs, a finding that highlights the role bacteria play in determining how well individuals respond to medications, they report June 3 . Scientists in the lab of senior author Andrew Goodman of Yale's Microbial Sciences Institute and the Department of Microbial Pathogenesis also pinpointed the microbial genes responsible for many of these drug-metabolizing activities.

Health - Pharmacology - 01.06.2019
Immunotherapy improves five-year survival rate of people with advanced lung cancer
In a study led by UCLA investigators, treatment with the immunotherapy drug pembrolizumab helped more than 15% of people with advanced non-small cell lung cancer live for at least five years — and 25% of patients whose tumor cells had a specific protein lived at least that long. When the study began in 2012, the average five-year survival rate was just 5.5% for people with that type of cancer.

Pharmacology - Health - 31.05.2019
Law backs doctors who prescribe opioids to the dying
Law backs doctors who prescribe opioids to the dying
Some doctors fear litigation and professional ruin if they are seen to have overprescribed opioids to terminally ill patients, according to a University of Queensland researcher. Palliative care expert Professor Geoffrey Mitchell said opioid overuse and some states' new assisted dying legislation had put end-of-life care clinicians “between a rock and a hard place”.

Health - Pharmacology - 30.05.2019
'switch' that helps breast cancer spread around the body
’switch’ that helps breast cancer spread around the body
Researchers have unveiled clues into how breast cancer cells spread around the body. The early-stage research, led by scientists from Imperial College London and The Institute of Cancer Research , London, identified a genetic ‘switch' in breast cancer cells that boosts the production of a type of internal scaffolding.

Life Sciences - Pharmacology - 28.05.2019
Cranberries join forces with antibiotics to fight bacteria
The global spread of antibiotic resistance is undermining decades of progress in fighting bacterial infections. Due to the overuse of antibiotics in medicine and agriculture, we are on the cusp of returning to a pre-antibiotic era in which minor infections can once again become deadly. Therefore, countering the fall in antibiotic efficacy by improving the effectiveness of currently available antibiotics is a crucial goal.

Life Sciences - Pharmacology - 24.05.2019
Nerve stimulation could provide new treatment option for most common type of stroke
Research led by a UCLA scientist found that a new nerve stimulation therapy to increase blood flow could help patients with the most common type of stroke up to 24 hours after onset. A study of 1,000 patients found evidence that the technique, called active nerve cell cluster stimulation, reduced the patients' degree of disability three months after they suffered an acute cortical ischemic stroke, which affects the surface of the brain.

Health - Pharmacology - 23.05.2019
Trial of potential new treatment for type 1 diabetes
Researchers at Cardiff and Swansea Universities are running a new trial to investigate whether a medicine currently used for the skin condition psoriasis could also be used to help people with type 1 diabetes produce some of their own insulin. Over 300,000 people in the UK have Type 1 diabetes and the drug used to treat them - insulin - has not changed in 98 years.

Health - Pharmacology - 23.05.2019
WHRY funds studies on pain relief, cannabis, and sex differences in disease
Women's Health Research at Yale (WHRY) today announced funding for first-of-their-kind studies on pain relief, cannabis, and the genetic basis of sex differences across a broad range of ailments, including Alzheimer's disease and heart disease. " We are changing science to improve lives by addressing what makes us unique as individuals," said Dr. Carolyn M. Mazure, director of WHRY.

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