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Pharmacology



Results 81 - 100 of 165.


Life Sciences - Pharmacology - 20.03.2019
Nicotine addiction from vaping is a bigger problem than teens realize
As the vaping epidemic continues, researchers point to well-known health risks associated with nicotine. Data show clearly that young people are vaping in record numbers. And despite the onslaught of reports and articles highlighting not only its dangers but the marketing tactics seemingly aimed to hook teens and young adults, the number of vaping users continues to climb.  These teens may be overlooking (or underestimating) a key ingredient in the vapors they inhale: nicotine.

Health - Pharmacology - 18.03.2019
Shows novel use of mosquito-killing drug may reduce childhood malaria
Childhood malaria episodes could be reduced by 20% during malaria transmission season if an entire village population were given the mosquito-killing drug ivermectin or IVM every three weeks, according to a new study published in The Lancet international medical journal. The study represents the first scientific evidence that repeated mass administration of IVM can reduce malaria incidence in children aged five or younger without an increase in adverse events for the wider population given the drug, the researchers said.

Pharmacology - Health - 18.03.2019
Caterpillars could hold the secret to new treatment for Osteoarthritis
A substance from a fungus that infects caterpillars could offer new treatment hope for sufferers of osteoarthritis according to new research. Cordycepin is an active compound isolated from the caterpillar fungus Cordyceps militaris and has proved to be effective in treating osteoarthritis by blocking inflammation in a new way, through reducing a process called polyadenylation.

Life Sciences - Pharmacology - 14.03.2019
A new approach to drugging a difficult cancer target
A new approach to drugging a difficult cancer target
Study suggests an alternative way to treat tumors that are dependent on the cancer-promoting Myc protein. One of the most common cancer-promoting genes, known as Myc, is also one of the most difficult to target with drugs. Scientists have long tried to develop drugs that block the Myc protein, but so far their efforts have not been successful.

Pharmacology - Health - 13.03.2019
New cholesterol-lowering drug could help patients unable to take statins
New cholesterol-lowering drug could help patients unable to take statins
A new class of oral cholesterol-lowering drug could help patients unable to take statins due to side effects. The findings come from the largest study to date to test the effectiveness and safety of bempedoic acid, an oral medication - yet to be approved in Europe - which inhibits the body's ability to create the building blocks of cholesterol.

Health - Pharmacology - 13.03.2019
Stress hormones promote breast cancer metastasis
It has long been thought that stress contributes to cancer progression. Scientists from the University of Basel and the University Hospital of Basel have deciphered the molecular mechanisms linking breast cancer metastasis with increased stress hormones. In addition, they found that synthetic derivatives of stress hormones, which are frequently used as anti-inflammatory in cancer therapy, decrease the efficacy of chemotherapy.

Pharmacology - Health - 13.03.2019
Molecular patterns could better predict breast cancer recurrence
The genetic and molecular make-up of individual breast tumours holds clues to how a woman's disease could progress, including the likelihood of it coming back after treatment, and in what time frame, according to a study published in Nature.

Pharmacology - Health - 13.03.2019
Therapy could improve, prolong sight in those suffering vision loss
Therapy could improve, prolong sight in those suffering vision loss
Millions of Americans are progressively losing their sight as cells in their eyes deteriorate, but a new therapy developed by researchers at the University of California, Berkeley, could help prolong useful vision and delay total blindness. The treatment - involving either a drug or gene therapy - works by reducing the noise generated by nerve cells in the eye, which can interfere with vision much the way tinnitus interferes with hearing.

Pharmacology - Health - 13.03.2019
"Inactive" ingredients may not be
Most pills contain compounds with potential to cause allergic reactions or discomfort in some patients. These compounds, known as "inactive ingredients," help to stabilize the drug or aid in its absorption, and they can make up more than half of a pill's mass. While these components are usually considered benign, a new study from MIT and Brigham and Women's Hospital has found that nearly all pills and capsules contain some ingredients that can cause allergic reactions or irritations in certain patients.

Pharmacology - Health - 11.03.2019
Repurposing older drugs could raise new hope for breast cancer treatment
An estimated 15 to 20 percent of all breast cancer patients are "triple negative," meaning women lack three crucial treatment targets-the estrogen receptor, the progesterone receptor and human epidermal growth factor receptor 2. Because they lack these targets, most triple negative patients are treated with standard chemotherapy, rather than the preferred targeted drugs.

Health - Pharmacology - 11.03.2019
Zinc could help as non-antibiotic treatment for UTIs
Zinc could help as non-antibiotic treatment for UTIs
New details about the role of zinc in our immune system could help the development of new non-antibiotic treatment strategies for bacterial diseases, such as urinary tract infections (UTIs). UTIs are one of the most common bacterial infections worldwide with about 150 million cases each year, and can lead to serious conditions such as kidney infection and sepsis.

Pharmacology - Health - 07.03.2019
Potential new treatment for heart attack
Scientists have found a potential new drug for treating the heart damage caused by a heart attack - by targeting the way the heart reacts to stress. This is the finding of new research, by scientists at Imperial College London and published in the journal Cell Stem Cell. There are no existing therapies that directly address the problem of muscle cell death Professor Michael Schneider Study author The research team, part-funded by the British Heart Foundation (BHF) used stem cells to grow heart tissue and mimic a ‘heart attack in a dish'.

Health - Pharmacology - 07.03.2019
Targeting inflammation for new Parkinson’s disease treatments
Researchers from The University of Queensland will investigate the potential of existing drugs to be repurposed to fight Parkinson's disease thanks to a new research grant. The research will be funded by The Michael J. Fox Foundation for Parkinson's Research and Shake It Up Australia Foundation and headed by UQ Centre for Clinical Research Group Leader Dr Richard Gordon.

Health - Pharmacology - 06.03.2019
New Hepatitis C cases down by almost 70 per cent in HIV positive men in London
New cases of hepatitis C amongst HIV positive men in London have fallen by nearly 70 per cent in recent years. The new analysis of data from three clinics in London found 256 men were diagnosed between 2013-2018. New infections peaked at 17 for every 1000 people studied in 2015 and fell to six by 2018.

Pharmacology - Health - 05.03.2019
HIV remission achieved in second patient
A second person has experienced sustained remission from HIV-1 after ceasing treatment, reports a paper led by UCL and Imperial College London. The case report comes ten years after the first such case, known as the ‘Berlin Patient.' Both patients were treated with stem cell transplants from donors carrying a genetic mutation that prevents expression of an HIV receptor CCR5.

Pharmacology - Health - 05.03.2019
Tissue model reveals how RNA will act on the liver
Tissue model reveals how RNA will act on the liver
Studies could speed the development of new treatments for liver disease. Novel therapies based on a process known as RNA interference (RNAi) hold great promise for treating a variety of diseases by blocking specific genes in a patient's cells. Many of the earliest RNAi treatments have focused on diseases of the liver, because RNA-carrying particles tend to accumulate in that organ.

Life Sciences - Pharmacology - 05.03.2019
Could genetic breakthrough finally help take the sting out of mouth ulcers?
A large breakthrough has been made in the genetic understanding of mouth ulcers which could provide potential for a new drug to prevent or heal the painful lesions. Mouth ulcers affect up to 25 per cent of young adults and a higher proportion of children. Previous research has shown that mouth ulcers are partially heritable, but until now there has been little evidence linking specific genes or genomic regions to mouth ulcers.

Pharmacology - Health - 05.03.2019
HIV remission achieved in second patient
HIV remission achieved in second patient
A second person has experienced sustained remission from HIV-1 after ceasing treatment, according to a study published today in Nature.

Health - Pharmacology - 05.03.2019
’Test and Treat’ reduces new HIV infections by a third in African communities
Results from largest ever HIV prevention trial suggest strategy could make a significant contribution to controlling epidemic New HIV infections in southern Africa could be reduced substantially by offering entire communities voluntary HIV testing, and immediately referring those who test positive for HIV treatment in line with local guidelines, according to new research presented at the Conference on Retroviruses and Opportunistic Infections (CROI) in Seattle, USA today.

Pharmacology - Chemistry - 04.03.2019
When changing one atom makes molecules better
Chemists in Vienna find a method to replace hydrogen with fluorine in organic molecules The development and improvement of pharmaceuticals plays the central role in the ongoing battle against human disease. Organic synthesis is the field that enables these developments as it offers the toolbox to diversify chemical structures.