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Pharmacology



Results 81 - 100 of 219.


Innovation / Technology - Pharmacology - 22.05.2019
MaaT Pharma expands patent portfolio with three granted patents covering its microbiome restoration biotherapeutic platform
MaaT Pharma expands patent portfolio with three granted patents covering its microbiome restoration biotherapeutic platform
First patents to cover the fundamental processes for accessing the human gut microbiome as biotherapeutics. MaaT Pharma's microbiome sample collection and administration devices receive CE mark for use in collecting and administrating gut-derived samples as biotherapeutics to patients.

Pharmacology - Health - 21.05.2019
Using 3D to test personalised treatments in five days
Using 3D to test personalised treatments in five days
UNIGE researchers have developed a cell co-culture platform that can reproduce a patient's tumour in 3D and test the best treatment combinations for its specific case in just five days. Why doesn't the same treatment work in the same way for every patient? How can a drug's performance be optimised without causing side effects due to an excessive dosage? In an attempt to answer these questions, researchers at the University of Geneva (UNIGE), Switzerland, have devised a cell co-culture platform that reproduces a patient's tumour structure in 3D.

Pharmacology - Life Sciences - 20.05.2019
New method simplifies the search for protein receptor complexes, speeding drug development
For a drug to intervene in cells or entire organs that are not behaving normally, it must first bind to specific protein receptors in the cell membranes. Receptors can change their molecular structure in a multitude of ways during binding - and only the right structure will “unlock” the drug's therapeutic effect.

Pharmacology - Health - 17.05.2019
’Stepped’ treatment reduces drinking in patients with HIV
People with HIV who drink too much were more likely to reduce drinking after undergoing an approach to care known as integrated stepped alcohol treatment, according to a Yale-led study. The finding supports greater use of this treatment model in HIV clinics to improve outcomes for patients with both HIV and drinking problems, the researchers said.

Health - Pharmacology - 16.05.2019
’Smart’ insulin could prevent hypoglycemia during diabetes treatment
UCLA bioengineers and their colleagues have developed a new type of insulin that could help prevent hypoglycemia in people who use the drug to manage diabetes. The treatment is being evaluated for potential clinical trials and, if successful, could change diabetes care. The study was published in the Proceedings of the National Academy of Sciences.

Health - Pharmacology - 15.05.2019
Study identifies how cancer drug inhibits DNA repair in cancer cells
According to researchers at Yale Cancer Center , a cancer drug thought to be of limited use possesses a superpower of sorts: It is able to stop certain cancer cells from repairing their DNA in order to survive. The study, published today Translational Medicine , suggests that combining this drug, cediranib, with other agents could potentially deliver a lethal blow in cancer that uses a specific pathway - or process - to create DNA repair cells.

Pharmacology - Health - 14.05.2019
Decoy antibiotics could get around bacteria's defences
Decoy antibiotics could get around bacteria’s defences
Imperial medical students have helped to devise a new type of 'decoy' drug to tackle infections that are resistant to antibiotics. In tests with cell cultures, the new drug successfully killed a strain of drug-resistant bacteria. It works by delivering two antibiotics, one of which is effectively hidden.

Life Sciences - Pharmacology - 14.05.2019
Second grant to bring research to market
05/14/2019 Getting an accurate picture of the real-time transcriptional activity of a cell: This is the goal of a new research project at the University of Würzburg which is funded by the European Research Council. If you paid attention during biology lessons, you may remember that genetic information in human cells is contained in the cell nucleus as a DNA double helix.

Pharmacology - 13.05.2019
Biomarker reveals PTSD sufferers at risk of suicide
The risk of suicide among individuals with post-traumatic stress disorder (PTSD) is much higher than the general population, but identifying those individuals at greatest risk has been difficult. However, a team at Yale has discovered a biological marker linked to individuals with PTSD who are most likely to think about suicide, the researchers report May 13 in the journal Proceedings of the National Academy of Sciences.

Pharmacology - Health - 13.05.2019
Researchers identify faster, more effective drug combination regimens to treat tuberculosis
Tuberculosis is a potentially deadly though curable disease. Each year about 10 million people develop active cases, and 1.6 million people die. In addition, about 1.7 billion people around the world are infected with TB bacteria, which can lie dormant for weeks to years, then become active and cause disease in up to 10 percent of those who are infected.

Health - Pharmacology - 09.05.2019
Smart design could prevent drug resistance in new malaria treatments
Smart design could prevent drug resistance in new malaria treatments
Researchers have overcome malaria parasites' resistance to potential new drugs by studying how it evolves. In a paper published today in Cell Chemical Biology , scientists from the Francis Crick Institute and Imperial College London studied malaria parasites resistant to a promising new class of candidate antimalarial drugs.

Life Sciences - Pharmacology - 08.05.2019
Knowledge for Growth 2019
5 Flemish universities reveal innovative state-of-the-art biotech research No less than 25 technologies in drug screening, therapy development, MedTech, digital health and AI will be showcased or pitched by the five Flemish universities at Europe's leading life sciences conference in Ghent.

Pharmacology - Chemistry - 07.05.2019
Scientists design better method to build molecules that could be drugs-in half the steps
Pharmaceutical chemists have a trick when they're designing a drug and want to make it easier for the body to take up without metabolic side effects: they might add a quaternary center-a carbon atom bonded to four other carbon atoms. The trouble is, such centers are often extremely hard to synthesize.

Pharmacology - Health - 07.05.2019
The science of cannabis and driving
The science of cannabis and driving
As medical cannabis becomes more readily available, it is imperative that any risks relating to driving are clarified via thorough research. The study, published in the journal  Psychopharmacology ,  and led by PhD student Thomas Arkell, compared the effects of standard THC-dominant cannabis, cannabis containing equivalent amounts of THC and CBD, and placebo cannabis on simulated driving and cognitive performance.

Health - Pharmacology - 03.05.2019
Clinical trial begins to test universal vaccine against canine cancer
David Vail, right, professor and oncologist at the UW School of Veterinary Medicine, delivers the very first vaccine in the Vaccination Against Canine Cancer Study to Trilly, a nine-year-old Gordon Setter, as she is held by veterinarian Kara Magee, left, and veterinary technician Rubi Hayem. Photo by Meghan Lepisto On Thursday, May 2, the very first dog received the very first vaccine intended to protect her from cancer.

Pharmacology - 03.05.2019
Wings for Life to boost spinal cord research
Wings for Life to boost spinal cord research
A world-wide competition will pit human against machine in a virtual high-tech car chase this weekend. The competition will raise money for spinal cord injury research - helping a University of Queensland researcher develop a new treatment. UQ School of Biomedical Sciences Associate Professor Marc Ruitenberg is one of few Australians to receive a Wings for Life Foundation grant.

Pharmacology - Life Sciences - 02.05.2019
Single molecule puts sperm on track
Sperm start their sprint to the ovum when they detect changes in the environment through a series of calcium channels arranged like racing stripes on their tails. A team of Yale researchers have identified a key molecule that helps activate sperm and acts as a sort of cellular GPS system that guides them to the egg.

Life Sciences - Pharmacology - 30.04.2019
Offers insight into the proteins in the brain that detect cannabis
Offers insight into the proteins in the brain that detect cannabis
Researchers at the University of Bristol have made new progress in understanding how cannabinoid receptors (CB1Rs), the proteins that detect the active components of marijuana, are controlled in the brain. The brain contains about 100 billion nerve cells that are constantly communicating with one another at specialised junctions called synapses.

Health - Pharmacology - 29.04.2019
Biomarker for chronic fatigue syndrome identified
Stanford scientists devised a blood-based test that accurately identified people with chronic fatigue syndrome, a new study reports. People suffering from a debilitating and often discounted disease known as chronic fatigue syndrome may soon have something they've been seeking for decades: scientific proof of their ailment.

Chemistry - Pharmacology - 29.04.2019
Bio-based chemicals could help reduce fossil fuel use
Petrochemicals, the oiland gas-derived compounds that serve as the molecular backbones for much of modern commerce, commanded a $539.3 billion market value in 2018. Replacing just a few of those petroleum products with chemicals made from plants or microbes could put a substantial dent in the world's fossil fuel consumption.

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