The Viennese scientists led by Maulide developed a method employing a 4-membered ring precursor to quickly assemble the macrocycle of the natural products
The research group of Nuno Maulide from the Faculty of Chemistry of the University of Vienna has, in cooperation with the Research Center for Molecular Medicine (CeMM) of the Austrian Academy of Sciences, achieved the synthesis of a potential immunosuppressive agent by modification of a naturally occurring compound. In this endeavour, the researchers have employed a masking trick to "hide" a reactive species inside the target molecule. The results were recently published in the renowned "Journal of the American Chemical Society". The Chemical fascination of Natural products - Chemists have long had a fascination with Nature. "Nature is an amazing Chemist", explains Nuno Maulide, Professor of Organic Chemistry at the University of Vienna and Austrian Scientist of the Year 2018, "especially since it has had millions of years to perfect a chemical machinery which is unrivalled in its complexity and efficiency". Particularly fascinating are the so-called "Natural products". These are substances produced by living organisms, for the most diverse functions: defense, sensing, signaling, among others.
TO READ THIS ARTICLE, CREATE YOUR ACCOUNT
And extend your reading, free of charge and with no commitment.
Your Benefits
- Access to all content
- Receive newsmails for news and jobs
- Post ads
