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Pharmacology



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Pharmacology - Health - 24.01.2020
Drug used widely to treat eye condition has ’no benefit’
Researchers from the University of Bristol and University Hospital Southampton have found that a drug used widely to treat a common eye condition has 'no benefit' and should no longer be used. Eplerenone, which is primarily used to treat heart failure, is currently offered widely by ophthalmologists as a treatment for central serous chorioretinopathy (CSCR) based on limited clinical data.

Health - Pharmacology - 23.01.2020
Preventing metastasis by stopping cancer cells from making fat
In brief  (18 seconds of reading): Olivier Feron , a UCLouvain researcher, studies how cancer spreads through the body via metastasis His major discovery was that cancer cells multiply by using lipids as food. His latest discovery, published in the scientific , is that lipid storage promotes cancer invasiveness A new drug currently being tested to treat obesity may also help fight metastasis Olivier Feron, a researcher at the University of Louvain (UCLouvain) Institute of Experimental and Clinical Research, seeks to understand how metastases form from a tumour.

Health - Pharmacology - 23.01.2020
Reveals stark inconsistencies in official UK guidance on Lyme disease
Reveals stark inconsistencies in official UK guidance on Lyme disease
Research reveals stark inconsistencies in official UK guidance on Lyme disease Official guidance on the diagnosis and testing of Lyme disease contains worrying inconsistencies, according to a new research paper. Professor Alex Faulkner at the University of Sussex, and national patient organisation Lyme Research UK have revealed stark discrepancies between the different policy and clinical practice guidance documents issued by Public Health England and other health bodies.

Computer Science / Telecom - Pharmacology - 23.01.2020
Technique reveals whether models of patient risk are accurate
Technique reveals whether models of patient risk are accurate
Computer scientists' new method could help doctors avoid ineffective or unnecessarily risky treatments. After a patient has a heart attack or stroke, doctors often use risk models to help guide their treatment. These models can calculate a patient's risk of dying based on factors such as the patient's age, symptoms, and other characteristics.

Health - Pharmacology - 22.01.2020
Male fertility after chemotherapy: new questions raised
Channels McGill University News and Events A pilot study conducted by INRS and McGill researchers highlights the effect of chemotherapy on male fertility before and after puberty. "It is often thought that cancer treatments for prepubescent boys will have no effect on their fertility because their testicles would be "dormant".

Health - Pharmacology - 21.01.2020
Leuven researchers present technique to grow tissue implants for bone defects
Researchers from KU Leuven and University Hospitals Leuven have managed to engineer living implants in the lab by mimicking how bone tissue is created in an embryo. The technology paves the way for bone-regenerating tissue implants created on an industrial scale using 3D bioprinting. The researchers expect the first living implants to be available to patients in four years.

Health - Pharmacology - 21.01.2020
Immune cell health discovery could optimise cancer therapies
Scientists at UCL have discovered how immune cells, essential for tackling infections and cancers, are able to 'recycle' material within themselves in order to stay healthy and function, a breakthrough finding which could lead to more effective immunotherapies. In the study, published in Cell Reports , researchers investigated how 'autophagy' - the natural physiological process of 'self-eating' which allows intracellular components, such as mitochondria, to be degraded and replaced - takes place in liver-based T cells.

Health - Pharmacology - 21.01.2020
Putting a finger on the switch of chronic parasite infection
Putting a finger on the switch of chronic parasite infection
Researchers find master regulator needed for Toxoplasma gondii parasite to chronically infect host; promising step toward infection treatment, prevention. Toxoplasma gondii (T. gondii) is a parasite that chronically infects up to a quarter of the world's population, causing toxoplasmosis, a disease that can be dangerous, or even deadly, for the immunocompromised and for developing fetuses.

Health - Pharmacology - 21.01.2020
Our biological clock plays crucial role in healing from surgery
Channels McGill University News and Events If you have just had knee, shoulder or hip surgery, you may want to take anti-inflammatories in the morning or at noon, but not at night. A McGill-led study shows, for the first time, that circadian clock genes are involved in healing from surgery. Indeed, the researchers demonstrated that anti-inflammatory medications are most effective in promoting post-operative healing and recovery when taken during the active periods of our biological clocks.

Health - Pharmacology - 20.01.2020
Could reduce the risk of sudden cardiac death
New research has shown that by changing the time course of voltage change early when the heart cell contracts it is possible to both withhold a potentially lethal electrical disturbance and improve the strength of cardiac contraction in heart failure at the same time. The research led by the University of Bristol and funded by the Medical Research Council (MRC) is published today [20 January] in the Proceedings of the National Academy of Sciences (PNAS).

Pharmacology - 20.01.2020
Confirms lingering mood benefit of psychedelics
People who had recently used psychedelics such as psilocybin report a sustained improvement in mood and feeling closer to others after the high has worn off, shows a new Yale study published the week of Jan. 20 in the journal Proceedings of the National Academy of Sciences. The results of a field study of more than 1,200 people attending multi-day arts and music festivals in the United States and United Kingdom confirm previous laboratory research indicating that psychedelic substances enhance feelings of social connectedness and improve mental well-being, the authors say.

Health - Pharmacology - 20.01.2020
Refining Breast Cancer Classification by Multiplexed Imaging
Refining Breast Cancer Classification by Multiplexed Imaging
An imaging approach developed at UZH enables the study of breast cancer tissue in greater detail. It uses 35 biomarkers to identify the different cell types in breast tumors and its surrounding area compared to the current standard of testing single markers. This increases the precision of tumor analysis and classification - and improves personalized diagnostics for breast cancer patients.

Health - Pharmacology - 20.01.2020
Discovery of new T-cell raises prospect of 'universal' cancer therapy
Discovery of new T-cell raises prospect of ’universal’ cancer therapy
Researchers at Cardiff University have discovered a new type of killer T-cell that offers hope of a “one-size-fits-all” cancer therapy. T-cell therapies for cancer - where immune cells are removed, modified and returned to the patient's blood to seek and destroy cancer cells - are the latest paradigm in cancer treatments.

Health - Pharmacology - 20.01.2020
Blood test for eight gene signatures could predict onset of tuberculosis
Scientists at UCL have shown a blood test could predict the onset of tuberculosis three to six months before people become unwell, a finding which could help better target antibiotics and save countless lives. In the study, published in  The Lancet Respiratory Medicine , researchers sought to identify which, if any, gene expression signatures in blood could be used to predict the disease at a very early stage and before symptoms arise.

Pharmacology - Health - 20.01.2020
Prolonged breath-holding could help radiotherapy treatment of cardiac arrhythmias
A technique that enables patients suffering from heart conditions to hold their breath safely for over 5 minutes could have potential as part of a new treatment for cardiac arrhythmias, say researchers at the University of Birmingham. In a new study, published in Frontiers in Physiology, researchers initially proposed the technique as a new means for earlier diagnosis of ischaemic heart disease.

Pharmacology - Social Sciences - 20.01.2020
Racial disparities in drug prescriptions for dementia
Disparities in drug prescribing suggest that black and Asian people with dementia are not receiving the same quality of care as their white peers, according to a new UCL-led study in the UK. Asian people with dementia are less likely to receive anti-dementia drugs, and take them for shorter periods, according to the findings published in Clinical Epidemiology .

Pharmacology - Health - 16.01.2020
Cheap roundworm drug found to enhance the effects of chemotherapy in prostate cancer
Scientists at the University of Glasgow and Cancer Research UK Beatson Institute have tested close to 1000 existing medicines and discovered that a cheap drug commonly used to treat parasitic worm infection could be a game-changing treatment for prostate cancer. Prostate cancer is the most common cancer affecting men and the second most common cause of cancer death for men in the UK.

Pharmacology - Health - 16.01.2020
Patients needed for irritable bowel syndrome trial
Patients needed for irritable bowel syndrome trial
Patients in GP surgeries in Bristol are being invited to take part in a large trial of low-dose amitriptyline for irritable bowel syndrome (IBS) lead by researchers from the universities of Bristol, Leeds and Southampton. IBS is a common gut disorder affecting one in ten people. Abdominal pain, bloating, and altered bowel habit affect patients' quality of life substantially and can force them to take days off work.

Pharmacology - Life Sciences - 16.01.2020
Probiotic drink could offer new way to combat antibiotic resistance
A probiotic drink could become a promising new weapon in the battle against antibiotic resistant bacteria, after a team of scientists at the University of Birmingham engineered and patented a key genetic element that can tackle the genetic basis of resistance. The team is now seeking funding for a clinical trial for the drink which has potential to work against many resistant bacteria commonly found in the human gut including E. coli, Salmonella and Klebsiella pneumoniae.

Pharmacology - Health - 15.01.2020
Stepping up to the challenge: studying drug dosage during an Ebola outbreak
A specialist technique used to study drugs has been completed for the first time during an outbreak of Ebola virus disease. The study published today in eBiomedicine was a collaboration of researchers from Sierra Leone and the University's of Glasgow, Oxford, Cambridge and the Liverpool School of Tropical Medicine.

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