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Pharmacology - Health - 29.01.2020
New guidelines will improve treatment for patients with hyperthyroidism
Scientists have examined a key receptor for the first time at high resolution - broadening understanding of how it might function, and opening the door to future improvements in treating conditions such as type 2 diabetes - a significant global health problem. Glucagon-like peptide-1 receptors (GLP1R) are found on insulin-producing beta cells of the pancreas and neurons in the brain.

Pharmacology - Health - 27.01.2020
Birmingham’s musical welcome for Chinese Year of the Rat
Scientists have examined a key receptor for the first time at high resolution - broadening understanding of how it might function, and opening the door to future improvements in treating conditions such as type 2 diabetes - a significant global health problem. Glucagon-like peptide-1 receptors (GLP1R) are found on insulin-producing beta cells of the pancreas and neurons in the brain.

Health - Pharmacology - 27.01.2020
Researchers showcase projects to tackle major health problems
Researchers showcase projects to tackle major health problems
Nineteen Imperial fellows showcased research projects aimed at tackling global health problems and disease challenges at a special celebration event. The Imperial 4i Clinician Scientist Training Scheme Celebration event took place last month at Imperial's South Kensington Campus. Fellows on the programme presented and showcased posters of a range of research projects icluding work in cardiology, rheumatology, infectious diseases and microbiology to an audience of senior academics and clinicians at Imperial College London and Imperial College Healthcare NHS Trust.

Life Sciences - Pharmacology - 27.01.2020
Drug improves symptoms of autism by targeting brain's chemical messengers
Drug improves symptoms of autism by targeting brain’s chemical messengers
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Health - Pharmacology - 24.01.2020
Researchers obtain 'high-definition' view of diabetes-related proteins
Researchers obtain ’high-definition’ view of diabetes-related proteins
A technique that enables patients suffering from heart conditions to hold their breath safely for over 5 minutes could have potential as part of a new treatment for cardiac arrhythmias, say researchers at the University of Birmingham. In a new study, published in Frontiers in Physiology, researchers initially proposed the technique as a new means for earlier diagnosis of ischaemic heart disease.

Life Sciences - Pharmacology - 24.01.2020
Pain treatment using human stem cells a success
Pain treatment using human stem cells a success
Human stem cells and "pain-killing neurons" have successfully relieved chronic pain in mice. The breakthrough method may be tested on human patients suffering untreatable pain within five years. Researchers at the University of Sydney have used human stem cells to make pain-killing neurons that provide lasting relief in mice, without side effects, in a single treatment.

Pharmacology - Health - 24.01.2020
Drug used widely to treat eye condition has ’no benefit’
Researchers from the University of Bristol and University Hospital Southampton have found that a drug used widely to treat a common eye condition has 'no benefit' and should no longer be used. Eplerenone, which is primarily used to treat heart failure, is currently offered widely by ophthalmologists as a treatment for central serous chorioretinopathy (CSCR) based on limited clinical data.

Health - Pharmacology - 24.01.2020
Can lithium halt progression of Alzheimer’s disease?
Channels McGill University News and Events McGill researchers' findings show that may be the case There remains a controversy in scientific circles today regarding the value of lithium therapy in treating Alzheimer's disease. Much of this stems from the fact that because the information gathered to date has been obtained using a multitude of differential approaches, conditions, formulations, timing and dosages of treatment, results are difficult to compare.

Health - Pharmacology - 23.01.2020
Preventing metastasis by stopping cancer cells from making fat
In brief  (18 seconds of reading): Olivier Feron , a UCLouvain researcher, studies how cancer spreads through the body via metastasis His major discovery was that cancer cells multiply by using lipids as food. His latest discovery, published in the scientific , is that lipid storage promotes cancer invasiveness A new drug currently being tested to treat obesity may also help fight metastasis Olivier Feron, a researcher at the University of Louvain (UCLouvain) Institute of Experimental and Clinical Research, seeks to understand how metastases form from a tumour.

Health - Pharmacology - 23.01.2020
Reveals stark inconsistencies in official UK guidance on Lyme disease
Reveals stark inconsistencies in official UK guidance on Lyme disease
Research reveals stark inconsistencies in official UK guidance on Lyme disease Official guidance on the diagnosis and testing of Lyme disease contains worrying inconsistencies, according to a new research paper. Professor Alex Faulkner at the University of Sussex, and national patient organisation Lyme Research UK have revealed stark discrepancies between the different policy and clinical practice guidance documents issued by Public Health England and other health bodies.

Computer Science - Pharmacology - 23.01.2020
Technique reveals whether models of patient risk are accurate
Technique reveals whether models of patient risk are accurate
Computer scientists' new method could help doctors avoid ineffective or unnecessarily risky treatments. After a patient has a heart attack or stroke, doctors often use risk models to help guide their treatment. These models can calculate a patient's risk of dying based on factors such as the patient's age, symptoms, and other characteristics.

Health - Pharmacology - 22.01.2020
Male fertility after chemotherapy: new questions raised
Channels McGill University News and Events A pilot study conducted by INRS and McGill researchers highlights the effect of chemotherapy on male fertility before and after puberty. "It is often thought that cancer treatments for prepubescent boys will have no effect on their fertility because their testicles would be "dormant".

Health - Pharmacology - 21.01.2020
Leuven researchers present technique to grow tissue implants for bone defects
Researchers from KU Leuven and University Hospitals Leuven have managed to engineer living implants in the lab by mimicking how bone tissue is created in an embryo. The technology paves the way for bone-regenerating tissue implants created on an industrial scale using 3D bioprinting. The researchers expect the first living implants to be available to patients in four years.

Health - Pharmacology - 21.01.2020
Immune cell health discovery could optimise cancer therapies
Scientists at UCL have discovered how immune cells, essential for tackling infections and cancers, are able to 'recycle' material within themselves in order to stay healthy and function, a breakthrough finding which could lead to more effective immunotherapies. In the study, published in Cell Reports , researchers investigated how 'autophagy' - the natural physiological process of 'self-eating' which allows intracellular components, such as mitochondria, to be degraded and replaced - takes place in liver-based T cells.

Health - Pharmacology - 21.01.2020
Putting a finger on the switch of chronic parasite infection
Putting a finger on the switch of chronic parasite infection
Researchers find master regulator needed for Toxoplasma gondii parasite to chronically infect host; promising step toward infection treatment, prevention. Toxoplasma gondii (T. gondii) is a parasite that chronically infects up to a quarter of the world's population, causing toxoplasmosis, a disease that can be dangerous, or even deadly, for the immunocompromised and for developing fetuses.

Health - Pharmacology - 21.01.2020
Our biological clock plays crucial role in healing from surgery
Channels McGill University News and Events If you have just had knee, shoulder or hip surgery, you may want to take anti-inflammatories in the morning or at noon, but not at night. A McGill-led study shows, for the first time, that circadian clock genes are involved in healing from surgery. Indeed, the researchers demonstrated that anti-inflammatory medications are most effective in promoting post-operative healing and recovery when taken during the active periods of our biological clocks.

Health - Pharmacology - 20.01.2020
Could reduce the risk of sudden cardiac death
New research has shown that by changing the time course of voltage change early when the heart cell contracts it is possible to both withhold a potentially lethal electrical disturbance and improve the strength of cardiac contraction in heart failure at the same time. The research led by the University of Bristol and funded by the Medical Research Council (MRC) is published today [20 January] in the Proceedings of the National Academy of Sciences (PNAS).

Pharmacology - 20.01.2020
Confirms lingering mood benefit of psychedelics
People who had recently used psychedelics such as psilocybin report a sustained improvement in mood and feeling closer to others after the high has worn off, shows a new Yale study published the week of Jan. 20 in the journal Proceedings of the National Academy of Sciences. The results of a field study of more than 1,200 people attending multi-day arts and music festivals in the United States and United Kingdom confirm previous laboratory research indicating that psychedelic substances enhance feelings of social connectedness and improve mental well-being, the authors say.

Health - Pharmacology - 20.01.2020
Refining Breast Cancer Classification by Multiplexed Imaging
Refining Breast Cancer Classification by Multiplexed Imaging
An imaging approach developed at UZH enables the study of breast cancer tissue in greater detail. It uses 35 biomarkers to identify the different cell types in breast tumors and its surrounding area compared to the current standard of testing single markers. This increases the precision of tumor analysis and classification - and improves personalized diagnostics for breast cancer patients.

Health - Pharmacology - 20.01.2020
Discovery of new T-cell raises prospect of 'universal' cancer therapy
Discovery of new T-cell raises prospect of ’universal’ cancer therapy
Researchers at Cardiff University have discovered a new type of killer T-cell that offers hope of a "one-size-fits-all" cancer therapy. T-cell therapies for cancer - where immune cells are removed, modified and returned to the patient's blood to seek and destroy cancer cells - are the latest paradigm in cancer treatments.
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