According to scientific estimations, humans are exposed to 10,000 to 100,000 environmental and exogenous compounds in an individual lifetime. Various molecules as well as co-exposures can impact drug efficacy.
According to scientific estimations, humans are exposed to 10,000 to 100,000 environmental and exogenous compounds in an individual lifetime. Various molecules as well as co-exposures can impact drug efficacy. Pixabay) - High-resolution mass spectrometry promotes new methods for analysis Humans are exposed to various environmental or dietary molecules that can attenuate or even increase the effect of therapeutic drugs. Studies on the industrial chemical bisphenol A and the phytoestrogen genistein, for example, have shown drug-exposome interactions. However, interactions between exposures and therapeutic agents have not been systematically investigated to date, conclude chemists Benedikt Warth and Manuel Pristner at the University of Vienna in a review article published in "Trends in Pharmacological Sciences". Recent advances in mass spectrometry are highly beneficial to the concept of systematic analysis, with high potential to elevate precision medicine to an unprecedented level. According to scientific estimations, humans are exposed to at least 10,000 to 100,000 environmental and exogenous compounds in an individual lifetime, which are mainly absorbed through our dietary.
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