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Pharmacology



Results 41 - 60 of 469.


Pharmacology - 12.11.2020
Interview: Developing a new immunotherapy to gain control of cancer
Scientists at UCL Cancer Institute have developed an experimental immunotherapy drug, which harnesses the immune system in a new way to kill cancer cells. Here lead researcher, Professor Sergio Quezada, discusses the groundbreaking discovery and its potential. "This is not the cure to cancer. I think that's very important to clarify.

Health - Pharmacology - 12.11.2020
Anti-ageing therapy against metastases
A preclinical study conducted at the Institute of Oncology Research (IOR, affiliated to USI) reveals the role of aging cells in the formation of metastases and identifies a drug capable of blocking them. The work of the group of researchers in Switzerland, Italy and the United States, led by Prof. Andrea Alimonti, is published in the important scientific journal Cancer Cell.

Chemistry - Pharmacology - 12.11.2020
Interactive virtual reality emerges as a new tool for drug design against COVID-19
Bristol scientists have demonstrated a new virtual reality [VR] technique which should help in developing drugs against the SARS-CoV-2 virus - and enable researchers to share models and collaborate in new ways. The innovative tool, created by University of Bristol researchers, and published in the Journal of Chemical Information and Modeling, will help scientists around the world identify anti-viral drug leads more rapidly.

Health - Pharmacology - 11.11.2020
Insights into ’significant’ avoidable harm in primary care
A national study in England has revealed the extent of incidents of significant avoidable harm in primary care. Thirteen GPs reviewed case notes of more than 90,000 patients in three regions across England over a 12-month period as part of the study. They found the main causes of avoidable harm were diagnostic error (more than 60%), medication incidents (more than 25%) and delayed referrals (nearly 11%), and that 80% of incidents could have been identified sooner or prevented if action had been taken.

Pharmacology - 11.11.2020
Looking through the door of meth labs
Methamphetamine 'cooks' in domestic labs are most likely to be male, Caucasian and about 30 years' old, according to University of Queensland researchers. Their study included 125 cooks from 24 countries, providing some insight into the illicit activity characterised in the popular television series Breaking Bad.

Health - Pharmacology - 10.11.2020
Vitamin D and omega-3 fatty acids promote health in subgroups of active elderly people
The DO-HEALTH study examines the effect of simple measures on the health of healthy adults aged 70+. The first evaluation shows no significant improvement in terms of bone fractures, leg and memory function through the intake of vitamin D, omega-3 fatty acids and strength training. However, certain groups could still benefit.

Pharmacology - Health - 10.11.2020
Next-generation immunotherapy entering early phase clinical trials
Scientists at UCL have invented a new experimental drug that aims to harness the full power of the immune system, launching a two-pronged response against cancer. The pioneering study in mice has been co-funded by Cancer Research UK. The innovative immunotherapy drug, developed by researchers at UCL Cancer Institute, targets suppressive 'regulatory' immune cells inside a tumour.

Health - Pharmacology - 10.11.2020
Newer medicine to prevent gout attacks is as safe as older treatment
A major new study examining the relative safety of medicines for the treatment of gout will be presented at the American College of Rheumatology Convergence conference and will be published in The Lancet. The FAST Study finds no increased risk of cardiovascular events with febuxostat as compared with allopurinol.

Pharmacology - Life Sciences - 04.11.2020
Scientists uncover new layer of complexity in how our bodies respond to drug treatments
Scientists from the University of Glasgow have played an important role in understanding why some patients respond better to drug treatments than others. The study - and involving the University of Glasgow and a number of international partners - uncovers a new layer of complexity in how the body responds to medical treatments by using the power of data analysis on GPCRs.

Health - Pharmacology - 04.11.2020
Funding for salmon drugs may help lower cost of treating deadly human diseases
The University of Glasgow has received funding to repurpose drugs that are currently used to treat some parasitic diseases in humans - Sleeping Sickness, Chagas Disease and Leishmaniasis - to manage amoebic gill disease in Atlantic salmon. Researchers hope that opening new markets for these drugs in the developed world will also help to drive down their costs in the developing world, where unaffordable healthcare can lead to many unnecessary deaths.

Health - Pharmacology - 04.11.2020
Transforming coronavirus proteins into nanoparticles may hold the key to an effective COVID-19 vaccine
Changing makeup of a specific protein has the potential to neutralize the virus Researchers from McGill University are part of an international team led by the University of Buffalo, which has discovered a technique that could help increase the effectiveness of vaccines against SARS-CoV-2, the virus that causes COVID-19.

Pharmacology - Health - 03.11.2020
New study into a rare type of cancer in abdomen lining shows possible immunotherapy treatment
A new study from the University of Birmingham has found that 50% of patients with a rare type of cancer that has spread into the lining of their abdomen may be suitable for immunotherapy treatment. Unfortunately for around 1% of bowel cancer patients, their cancer spreads to the lining of their abdomen (peritoneal cavity) - known as colorectal peritoneal metastasis (CPM).

Pharmacology - Health - 03.11.2020
Poisoning exposures in Australian schools
Poisoning exposures in Australian schools
New data shows poisoning exposures in children and adolescents while at school are relatively common and appear to be increasing, highlighting the need for more robust preventative measures. New research from the University of Sydney has found poisoning exposures in children and adolescents while at school are relatively common and appear to be increasing, highlighting the need for more robust prevention measures.

Health - Pharmacology - 02.11.2020
How the immune system remembers viruses
How the immune system remembers viruses
Immune response: memory T cells are formed earlier than previously thought For a person to acquire immunity to a disease, T cells must develop into memory cells after contact with the pathogen. Until now, the number of cells that do this was believed to depend above all on the magnitude of the initial immune response.

Pharmacology - 28.10.2020
Paracetamol poisonings up
Paracetamol poisonings up
In 2003, the painkiller paracetamol became available in Switzerland in tablets with a higher dose of the active ingredient. This correlates with an increase in cases of paracetamol poisoning in the country, as a data analysis by ETH researchers shows. Paracetamol is a popular source of pain relief. In Switzerland, it is available over the counter in 500 milligram tablets, but also in double the dose, in 1,000 milligram (1 gram) tablets when prescribed by a physician.

Health - Pharmacology - 28.10.2020
Antiviral drugs trialled in the early stages of COVID-19
Two antiviral drugs are being given to COVID-19 positive adults to establish if they stop the virus replicating, as part of a trial led by UCL scientists. The FLARE trial aims to see if favipiravir and lopinavir/ritonavir, alone or in combination, can inhibit viral replication in early infection - within the first few days of illness.

Pharmacology - Health - 27.10.2020
Common diabetes drugs may help prevent Parkinson’s
Elevated risk of Parkinson's disease among people with type 2 diabetes appears to be reduced by some medications used to treat their diabetes, finds a new study led by UCL researchers. The researchers are testing one of the drugs, called exenatide, as a potential Parkinson's treatment in an upcoming clinical trial, and the new findings, published in Brain , lend support to repurposing diabetes medications for people with Parkinson's.

Pharmacology - Health - 27.10.2020
High blood pressure and its drug treatment unlikely to increase entry of COVID-19 virus into cells
Fears that people with high blood pressure are more at risk from severe Covid-19 because it is easier for the virus to enter their cells and tissues have been laid to rest, thanks to research by an international team of scientists The team led by University of Manchester, and including University of Glasgow researchers, also show that speculation over some blood pressure lowering medications that they increase the risk of Covid-19 infection, is likely to be wrong.

Pharmacology - Health - 27.10.2020
Learning how to make shared decisions with virtual patients
Learning how to make shared decisions with virtual patients
Patients want to have a say in their medical treatment, especially when it will have a major impact on their life. Research shows that a shared decision-making process does indeed have positive effects. But how can a doctor learn how to approach this properly? The current training lacks sufficient opportunities to practise with patients.

Health - Pharmacology - 27.10.2020
How doctors can have more confidence in a COVID-19 diagnosis: analysis
University of Sydney researchers suggest using the methods of clinical epidemiology to help minimise uncertainty in a COVID-19 diagnosis and help public health decisions during the pandemic. A 26-year-old man in Sydney visits a clinician with a blocked nose, cough and fever in late March 2020. Could it be COVID-19, or another respiratory disease such as influenza? Frontline clinicians in the COVID-19 pandemic can use clinical epidemiology methods to be more confident in ruling in, or ruling out, a COVID-19 diagnosis in an individual patient, say researchers.