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Pharmacology - Life Sciences - 29.12.2021 
Omicron’s secrets revealed under a microscope
Thanks to the high-power electron microscopes at the Dubochet Center for Imaging (DCI), scientists were able to observe the configuration of the Omicron variant's spike protein at a near-atomic scale. This should provide fresh insight into the mechanisms the variant uses to evade vaccines and antibodies.
Health - Life Sciences - 27.12.2021 
’Battle of the sexes’ begins in womb as father and mother’s genes tussle over nutrition
Cambridge scientists have identified a key signal that the fetus uses to control its supply of nutrients from the placenta in a tug-of-war between genes inherited from the father and from the mother. The study, carried out in mice, could help explain why some babies grow poorly in the womb. The father's gene drives the fetus's demands for larger blood vessels and more nutrients, while the mother's gene in the placenta tries to control how much nourishment she provides Miguel Constância As the fetus grows, it needs to communicate its increasing needs for food to the mother.
Health - Life Sciences - 24.12.2021
Environment - Life Sciences - 23.12.2021
Life Sciences - Health - 23.12.2021 
Clues to treatment of schizophrenia and bipolar disorder found in recently evolved region of the ’dark genome’
Scientists investigating the DNA outside our genes - the 'dark genome' - have discovered recently evolved regions that code for proteins associated with schizophrenia and bipolar disorder. This opens up huge potential for new druggable targets. It's really exciting because nobody has ever looked beyond the genes for clues to understanding and treating these conditions before.
Life Sciences - 23.12.2021 
Daring to leave gaps in the genome
Research team at Göttingen University develops new method to complete genetic data The use of genetic information is now indispensable for modern plant breeding. Even though DNA sequencing has become much cheaper since the human genome was decoded for the very first time in 2003, collecting the full genetic information still accounts for a large part of the costs in animal and plant breeding.
Health - Life Sciences - 23.12.2021 
Dominant Alpha variant evolved to evade our innate immune system
The SARS-CoV-2 Alpha (B.1.1.7) variant mutated to evade our 'innate immune system', helping establish it as the world's first 'Variant of Concern', finds a new study led by researchers at UCL and the Quantitative Biosciences Institute, University of California San Francisco. Published in Nature , the study shows the Alpha variant, first identified in the UK, evolved to make more of its 'antagonism proteins' that nullify the body's first line of defence, known as the 'innate immune system'.
Life Sciences - Physics - 22.12.2021
Life Sciences - Environment - 22.12.2021 
Greater diversity of Iberian spiders previously unknown
Populations of peninsular spiders that make aerial spider webs and move around the air by ballooning (using the silk threads as parachutes) present a more homogeneous genetics structure and are better connected between them. However, species of nocturnal spiders, which hunt on the ground and have a low dispersal capacity, show less genetically connected populations and are more vulnerable to local extinction processes due to environmental factors.
Life Sciences - 22.12.2021
Life Sciences - Health - 22.12.2021 
New graphene-based neural probes improve detection of epileptic brain signals
New research published today has demonstrated that tiny graphene neural probes can be used safely to greatly improve our understanding of the causes of epilepsy. The graphene depth neural probe (gDNP) consists of a millimetre-long linear array of micro-transistors imbedded in a micrometre-thin polymeric flexible substrate.
Health - Life Sciences - 22.12.2021 
New grafting technique could combat the disease threatening Cavendish bananas
Scientists have found a novel way to combine two species of grass-like plant including banana, rice and wheat, using embryonic tissue from their seeds. The technique allows beneficial characteristics, such as disease resistance or stress tolerance, to be added to the plants.
Life Sciences - Campus - 22.12.2021 
Academic Education Can Positively Affect Aging of the Brain
The benefits of good education and lifelong learning extend into old age. The initial findings of a long-term study show that certain degenerative processes are reduced in the brains of academics. Their brains are better able to compensate age-related cognitive and neural limitations. A good education is an excellent way to embark on a successful career and develop your personality.
Health - Life Sciences - 22.12.2021 
T cells: No time to die
They are at the forefront in the fight against viruses, bacteria, and malignant cells: the T cells of our immune system. But the older we get, the fewer of them our body produces. Thus, how long we remain healthy also depends on how long the T cells survive. Researchers at the University of Basel have now uncovered a previously unknown signaling pathway essential for T cell viability.
Health - Life Sciences - 22.12.2021 
World’s first molecular-level analysis of Omicron variant spike protein
Findings show strong antibody evasion and binding with human cells that contribute to increased transmissibility-and that vaccination remains the best defence UBC researchers are the first in the world to conduct a molecular-level structural analysis of the Omicron variant spike protein. The analysis-done at near atomic resolution using a cryo-electron microscope-reveals how the heavily mutated variant infects human cells and is highly evasive of immunity.
Social Sciences - Life Sciences - 22.12.2021 
World’s oldest family tree provides new insights into kinship and burial practices in Neolithic times
By analyzing ancient DNA an international team of scientists with participation of Ron Pinhasi's team of the University of Vienna was able to retrace the world's oldest family tree. They took samples from a Neolithic tomb in Britain. In their study published they reveal undiscovered information about the structure of prehistoric families.
Life Sciences - Paleontology - 22.12.2021 
Modern mammals originated after dinosaur extinction, confirms new study
The most detailed timeline of mammal evolution to date has been set out in a new study co-led by UCL researchers. The Nature paper describes a new and fast computational approach to obtain precisely dated evolutionary trees, known as 'timetrees'. The authors used the novel method to analyse a mammal genomic dataset and answer a long-standing question around whether modern placental mammal groups originated before or after the Cretaceous-Palaeogene (K-Pg) mass extinction, which wiped out over 70% of all species, including all dinosaurs.
Paleontology - Life Sciences - 21.12.2021 
Exquisitely preserved embryo found inside fossilised dinosaur egg
A 72- to 66-million-year-old embryo found inside a fossilised dinosaur egg sheds new light on the link between the behaviour of modern birds and dinosaurs, according to a new study. The embryo, dubbed 'Baby Yingliang', was discovered in the Late Cretaceous rocks of Ganzhou, southern China and belongs to a toothless theropod dinosaur, or oviraptorosaur.
Life Sciences - Health - 21.12.2021 
Mechanism for DNA invasion of Adenoviral Covid-19 Vaccines Discovered
Adenoviruses have a linchpin protein that stabilizes their DNA until it reaches the infected cell's nucleus. The protein then detaches from the viral genome, and the virus uncoats. Only then are the genes released into the nucleus, which is necessary for the production of new viruses. This process, discovered by researchers at the University of Zurich, is a key for effective functioning of various Covid-19 vaccines.
Life Sciences - Health - 21.12.2021 
’The balance is extremely important’
When you enter the Institute of Neuroand Behavioural Biology at Badestraße 9 and go up the stairs on the left.. what you immediately see are the rows of pictures in the stairwell and the corridors. They look fascinating, in bright vibrant colours - but what they actually show is not apparent to the non-specialist at first glance.
Life Sciences
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Thanks to the high-power electron microscopes at the Dubochet Center for Imaging (DCI), scientists were able to observe the configuration of the Omicron variant's spike protein at a near-atomic scale. This should provide fresh insight into the mechanisms the variant uses to evade vaccines and antibodies.
Cambridge scientists have identified a key signal that the fetus uses to control its supply of nutrients from the placenta in a tug-of-war between genes inherited from the father and from the mother. The study, carried out in mice, could help explain why some babies grow poorly in the womb. The father's gene drives the fetus's demands for larger blood vessels and more nutrients, while the mother's gene in the placenta tries to control how much nourishment she provides Miguel Constância As the fetus grows, it needs to communicate its increasing needs for food to the mother.
Our 10 most-read science news stories of 2021
From abdominal pain after eating certain foods to experimental hearing implants: in this overview, we present the most-read news items about research at KU Leuven in 2021. KU Leuven develops very potent antiviral against dengue 6 October Researchers have developed an inhibitor of the dengue virus. The antiviral molecule is effective against all known dengue variants and could be used for therapeutic and prevention purposes.
From abdominal pain after eating certain foods to experimental hearing implants: in this overview, we present the most-read news items about research at KU Leuven in 2021. KU Leuven develops very potent antiviral against dengue 6 October Researchers have developed an inhibitor of the dengue virus. The antiviral molecule is effective against all known dengue variants and could be used for therapeutic and prevention purposes.
Protecting ecosystems is better done regionally than locally
VUB biologists find missing link between biodiversity and ecosystem functioning Biologists from VUB and the University of Gothenburg in Sweden have demonstrated for the first time that it is not the local biodiversity in a specific place that is essential for maintaining a properly functioning ecosystem, but the biodiversity of the entire region.
VUB biologists find missing link between biodiversity and ecosystem functioning Biologists from VUB and the University of Gothenburg in Sweden have demonstrated for the first time that it is not the local biodiversity in a specific place that is essential for maintaining a properly functioning ecosystem, but the biodiversity of the entire region.
Scientists investigating the DNA outside our genes - the 'dark genome' - have discovered recently evolved regions that code for proteins associated with schizophrenia and bipolar disorder. This opens up huge potential for new druggable targets. It's really exciting because nobody has ever looked beyond the genes for clues to understanding and treating these conditions before.
Research team at Göttingen University develops new method to complete genetic data The use of genetic information is now indispensable for modern plant breeding. Even though DNA sequencing has become much cheaper since the human genome was decoded for the very first time in 2003, collecting the full genetic information still accounts for a large part of the costs in animal and plant breeding.
The SARS-CoV-2 Alpha (B.1.1.7) variant mutated to evade our 'innate immune system', helping establish it as the world's first 'Variant of Concern', finds a new study led by researchers at UCL and the Quantitative Biosciences Institute, University of California San Francisco. Published in Nature , the study shows the Alpha variant, first identified in the UK, evolved to make more of its 'antagonism proteins' that nullify the body's first line of defence, known as the 'innate immune system'.
How do our organs know when to stop growing?
A multidisciplinary team led by researchers from the University of Geneva and MPIPKS has solved with a mathematical equation the mystery of how an organ changes its size depending on the size of the animal. The smallest fish in the world, the Paedocypris, measures only 7 millimeters. This is nothing compared to the 9 meters of the whale shark.
A multidisciplinary team led by researchers from the University of Geneva and MPIPKS has solved with a mathematical equation the mystery of how an organ changes its size depending on the size of the animal. The smallest fish in the world, the Paedocypris, measures only 7 millimeters. This is nothing compared to the 9 meters of the whale shark.
Populations of peninsular spiders that make aerial spider webs and move around the air by ballooning (using the silk threads as parachutes) present a more homogeneous genetics structure and are better connected between them. However, species of nocturnal spiders, which hunt on the ground and have a low dispersal capacity, show less genetically connected populations and are more vulnerable to local extinction processes due to environmental factors.
Switching in the brain: a fresh perspective
Research team at Göttingen Campus investigates processing of sensory impressions The human brain is extremely dynamic. The connections between nerve cells change when we learn or forget. But our brain's computations change even faster than its structure: in a heartbeat, we shift our focus from what we see to what we hear or smell.
Research team at Göttingen Campus investigates processing of sensory impressions The human brain is extremely dynamic. The connections between nerve cells change when we learn or forget. But our brain's computations change even faster than its structure: in a heartbeat, we shift our focus from what we see to what we hear or smell.
New research published today has demonstrated that tiny graphene neural probes can be used safely to greatly improve our understanding of the causes of epilepsy. The graphene depth neural probe (gDNP) consists of a millimetre-long linear array of micro-transistors imbedded in a micrometre-thin polymeric flexible substrate.
Scientists have found a novel way to combine two species of grass-like plant including banana, rice and wheat, using embryonic tissue from their seeds. The technique allows beneficial characteristics, such as disease resistance or stress tolerance, to be added to the plants.
The benefits of good education and lifelong learning extend into old age. The initial findings of a long-term study show that certain degenerative processes are reduced in the brains of academics. Their brains are better able to compensate age-related cognitive and neural limitations. A good education is an excellent way to embark on a successful career and develop your personality.
They are at the forefront in the fight against viruses, bacteria, and malignant cells: the T cells of our immune system. But the older we get, the fewer of them our body produces. Thus, how long we remain healthy also depends on how long the T cells survive. Researchers at the University of Basel have now uncovered a previously unknown signaling pathway essential for T cell viability.
Findings show strong antibody evasion and binding with human cells that contribute to increased transmissibility-and that vaccination remains the best defence UBC researchers are the first in the world to conduct a molecular-level structural analysis of the Omicron variant spike protein. The analysis-done at near atomic resolution using a cryo-electron microscope-reveals how the heavily mutated variant infects human cells and is highly evasive of immunity.
By analyzing ancient DNA an international team of scientists with participation of Ron Pinhasi's team of the University of Vienna was able to retrace the world's oldest family tree. They took samples from a Neolithic tomb in Britain. In their study published they reveal undiscovered information about the structure of prehistoric families.
The most detailed timeline of mammal evolution to date has been set out in a new study co-led by UCL researchers. The Nature paper describes a new and fast computational approach to obtain precisely dated evolutionary trees, known as 'timetrees'. The authors used the novel method to analyse a mammal genomic dataset and answer a long-standing question around whether modern placental mammal groups originated before or after the Cretaceous-Palaeogene (K-Pg) mass extinction, which wiped out over 70% of all species, including all dinosaurs.
A 72- to 66-million-year-old embryo found inside a fossilised dinosaur egg sheds new light on the link between the behaviour of modern birds and dinosaurs, according to a new study. The embryo, dubbed 'Baby Yingliang', was discovered in the Late Cretaceous rocks of Ganzhou, southern China and belongs to a toothless theropod dinosaur, or oviraptorosaur.
Adenoviruses have a linchpin protein that stabilizes their DNA until it reaches the infected cell's nucleus. The protein then detaches from the viral genome, and the virus uncoats. Only then are the genes released into the nucleus, which is necessary for the production of new viruses. This process, discovered by researchers at the University of Zurich, is a key for effective functioning of various Covid-19 vaccines.
When you enter the Institute of Neuroand Behavioural Biology at Badestraße 9 and go up the stairs on the left.. what you immediately see are the rows of pictures in the stairwell and the corridors. They look fascinating, in bright vibrant colours - but what they actually show is not apparent to the non-specialist at first glance.
