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Pharmacology - Life Sciences - 29.12.2021
Omicron's secrets revealed under a microscope
Omicron’s secrets revealed under a microscope
Thanks to the high-power electron microscopes at the Dubochet Center for Imaging (DCI), scientists were able to observe the configuration of the Omicron variant's spike protein at a near-atomic scale. This should provide fresh insight into the mechanisms the variant uses to evade vaccines and antibodies.

Physics - Pharmacology - 27.12.2021
Optimization of mRNA containing nanoparticles
Optimization of mRNA containing nanoparticles
The research neutron source Hein Maier-Leibnitz (FRM II) at the Technical University of Munich (TUM) is playing an important role in the investigation of mRNA nanoparticles similar to the ones used in the Covid-19 vaccines from vendors BioNTech and Pfizer. Researchers at the Heinz Maier-Leibnitz Zentrum (MLZ) used the high neutron flux available in Garching to characterize various formulations for the mRNA vaccine and thus to lay the groundwork for improving the vaccine's efficacy.

Health - Pharmacology - 23.12.2021
UBC clinical trial supports new self-administered rapid antigen test
UBC clinical trial supports new self-administered rapid antigen test
Q&As Erik Rolfsen When it comes to COVID-19, peace of mind is difficult to come by. But thanks to new research compiled with data from UBC's first on-campus clinical study, a new self-administered rapid antigen test will soon be available in Canada. It's a tool that could help combat growing uncertainty, prevent transmission and potentially save lives.

Pharmacology - Health - 23.12.2021
Abiraterone could halve risk of prostate cancer death for some patients
Abiraterone could halve risk of prostate cancer death for some patients
Adding abiraterone to the standard treatment for locally advanced prostate cancer, where the cancer has a high chance of spreading, could halve the risk of death from the disease, according to the results of a UCL-led trial. The researchers suggest that hormone therapy using abiraterone with prednisolone, could significantly reduce prostate cancer deaths and improve outcomes for thousands of people every year.

Health - Pharmacology - 22.12.2021
Booster vaccination strongly enhances COVID-19 immunity in care home residents and staff - study
Booster vaccination strongly enhances COVID-19 immunity in care home residents and staff - study
Share this page Share on Twitter Share on facebook Share on linkedin Share on email A COVID-19 booster vaccination markedly increases immune response in residents and staff within care homes, making it vital that people living and working in these settings get their third 'jab', a new study reveals.

Health - Pharmacology - 22.12.2021
2021’s news highlights from the Faculty of Biology, Medicine and Health
Whether it's the continued impact of the Covid-19 pandemic or our world-leading science, our stories have been top news across the country and the world. Here's some of the most popular and interesting news releases from the Faculty of Biology, Medicine and Health in 2021.

Health - Pharmacology - 22.12.2021
Covid-19 Infections in Nursing Homes: Simulation model for optimal prevention and vaccination strategies
Covid-19 Infections in Nursing Homes: Simulation model for optimal prevention and vaccination strategies
Researchers from TU Graz and Complexity Science Hub (CSH) Vienna have developed a detailed epidemiological model for the spread of the coronavirus in nursing homes. This enables optimal prevention strategies to be identified, as practical experience in Caritas nursing homes has shown. Since the beginning of the coronavirus pandemic, residents of nursing homes have been particularly at risk.

Health - Pharmacology - 22.12.2021
Booster jabs strongly enhance Covid-19 immunity in care home residents and staff
Booster jabs strongly enhance Covid-19 immunity in care home residents and staff
A Covid-19 booster vaccination markedly increases immune response in residents and staff within care homes, according to a new preprint study co-led by UCL researchers, making it vital that people living and working in these settings get their third jab. Age and frailty are already recognised as major risk factors for severe Covid-19 outcomes, with elderly residents of long-term care facilities suffering much higher rates of mortality during the pandemic than the general population.

Health - Pharmacology - 21.12.2021
China-wide study will boost understanding of fatal surgical complication
China-wide study will boost understanding of fatal surgical complication
Share this page Share on Twitter Share on facebook Share on linkedin Share on email Older patients in hospitals across China took part in a major multi-centre open-label randomised clinical trial that showed there was no difference in post-operative delirium in older people with a hip fracture, if they had a general anaesthesia, or a regional anaesthesia.

Pharmacology - 21.12.2021
Four in ten consultations at GP clinics were with frequent attenders
A relatively small number of patients are accounting for a large proportion of GP workload, including face-to-face consultations, according to a UK study by University of Manchester experts. The study of over 160 million consultation events from 12.3 million patients, in 845 general practices between 2000 and 2019 showed four out of ten of the workload at GP clinics were with frequent attenders.

Pharmacology - Psychology - 21.12.2021
Botox Injections May Reduce Anxiety
FDA database of drug side effects indicates the benefit may hold up no matter where Botox is injected Botox, or Botulinum toxin, a medication derived from a bacterial toxin, is commonly injected to ease wrinkles, migraines, muscle spasms, excessive sweating and incontinence.

Pharmacology - 20.12.2021
Research highlights gap in methamphetamine use figures
Methamphetamine use could be two to four times higher than estimated figures in national surveys, researchers at The University of Queensland have found. Dr Gary Chan from UQ's National Centre for Youth Substance Use Research said the research investigated data collected between 2001 and 2019 and examined lifetime methamphetamine use for three main cohorts born between 1951-1960, 1961-1970 and 1971-1980.

Health - Pharmacology - 20.12.2021
Novel approach to COVID-19 vaccine shows early promise
Novel approach to COVID-19 vaccine shows early promise
Early studies in mice show this potential vaccine could produce stronger and longer lasting immunity to fight against variants. A Western University team's novel approach to developing a COVID-19 vaccine shows promise in inducing a robust immune response, early data shows. Several COVID-19 vaccines have been licensed and used for nearly one year now to protect people from the virus.

Health - Pharmacology - 20.12.2021
Covid-19 vaccine protection wanes after three months
Related Links Link to the study in the Lancet Covid-19 vaccine protection wanes after three months, study suggests The protection offered by the Oxford-Astra Zeneca Covid-19 vaccine declines after three months of receiving two doses, a study says. The findings - drawn from datasets in two countries - suggest that booster programmes are needed to help maintain protection from severe disease in those vaccinated with Oxford-Astra Zeneca, experts say.

Health - Pharmacology - 17.12.2021
Drug could more effectively treat patients hospitalised with COVID-19 pneumonia, early stage research finds
Share this page Share on Twitter Share on facebook Share on linkedin Share on email A proof-of-concept trial led by the University of Birmingham and University Hospitals Birmingham NHS Foundation Trust has identified a drug that may offer benefit some patients hospitalised with COVID-19 pneumonia.

Pharmacology - Health - 16.12.2021
Study dispels misconceptions about treating opioid use disorder patients
Given the magnitude of the opioid crisis in the United States, a growing number of patient advocates are calling for primary care physicians to assume greater responsibility for treatment of those with opioid use disorder. Yet while these primary care physicians are positioned to offer this treatment - and are already allowed to prescribe buprenorphine and naloxone treatment - many choose not to, citing a lack of institutional support and discomfort managing the more complex medical needs sometimes associated with this disorder.

Health - Pharmacology - 15.12.2021
Effective combination cancer treatment
Effective combination cancer treatment
Researchers at the Paul Scherrer Institute PSI have tested various methods to check how effective they are in combatting certain types of cancer. They found a combination of two preparations to be much more effective than treatment with just one of the two active substances. They have published their findings today in the medical journal Pharmaceutics .

Health - Pharmacology - 15.12.2021
New insights into impact of immune-suppressing treatments on COVID-19 vaccine effectiveness
Treatments used to help people with multiple sclerosis (MS) manage their condition can reduce the effectiveness of COVID-19 vaccines, according to a new study led by Cardiff University. Disease-modifying therapies (DMTs) are a group of treatments that suppress the body's immune system and are used by people with MS and other conditions such as cancer and rheumatoid disease.

Pharmacology - Health - 13.12.2021
New resistance-busting antibiotic combination could extend the use of ’last-resort’ antibiotics
Scientists have discovered a new potential treatment that has the ability to reverse antibiotic resistance in bacteria that cause conditions such as sepsis, pneumonia, and urinary tract infections. Carbapenems, such as meropenem, are a group of vital often 'last-resort' antibiotics used to treat serious, multi-drug resistant infections when other antibiotics, such as penicillin, have failed.

Health - Pharmacology - 10.12.2021
Prior SARS-CoV-2 infection increases strength and quality of immune response in double vaccinated care home staff and residents, reveals study
Share this page Share on Twitter Share on facebook Share on linkedin Share on whatsapp Share on email Elderly care home residents who have previously contracted and survived COVID-19 develop much stronger and higher antibody and cellular immune responses to two doses of vaccination than those without prior natural infection, finds new research led by the University of Birmingham.
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