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Health - Pharmacology - 31.05.2022
Vaccination strategy can be optimised with computer model
HU research team simulates COVID-19 outbreaks with virtual agents A new model for simulating COVID-19 outbreaks helps to develop the right strategy for herd immunity for every municipality and city - even in the event of vaccine shortages. For, even after two years of the pandemic, countries, municipalities and cities are still experiencing severe COVID-19 outbreaks.

Pharmacology - Health - 31.05.2022
Very high doses of cannabis component CBD don't affect driving
Very high doses of cannabis component CBD don’t affect driving
University of Sydney-led research finds that 1500mg, the highest daily medicinal dose of cannabidiol (CBD), has no impact on people's driving or cognitive abilities. Millions of consumers and patients around the world will be heartened by the results of the latest study on cannabis and driving. The University of Sydney-led finds that 1500mg, the highest daily medicinal dose of cannabidiol (CBD), has no impact on people's driving or cognitive abilities.

Health - Pharmacology - 31.05.2022
A World Premiere: For the First Time, a Human Liver Was Treated in a Machine and Then Successfully Transplanted
A World Premiere: For the First Time, a Human Liver Was Treated in a Machine and Then Successfully Transplanted
The multidisciplinary Zurich research team Liver4Life has succeeded in doing something during a treatment attempt that had never been achieved in the history of medicine until now: it treated an originally damaged human liver in a machine for three days outside of a body and then implanted the recovered organ into a cancer patient.

Health - Pharmacology - 30.05.2022
Rise in Guillain-Barré syndrome following AstraZeneca vaccine
Rise in Guillain-Barré syndrome following AstraZeneca vaccine
A correlation between a first dose of the AstraZeneca vaccine and a small but significant rise in cases of the serious neurological condition Guillain-Barré syndrome (GBS), has been identified by UCL scientists, as part of an analysis of NHS data. However, researchers say it remains unclear what the cause of the link is; furthermore the small numbers of GBS cases observed appear similar to increases previously seen in other mass vaccination campaigns.

Pharmacology - Health - 26.05.2022
Common drug-resistant superbug develops fast resistance to 'last resort' antibiotic
Common drug-resistant superbug develops fast resistance to ’last resort’ antibiotic
New research has found that Pseudomonas bacterium develops resistance much faster than usual to a common 'last-resort' antibiotic. A study published today in Cell Reports reveals how populations of a bacterium called Pseudomonas respond to being treated with Colistin, a 'last resort' antibiotic for patients who have developed multi-drug resistant infections.

Health - Pharmacology - 26.05.2022
Common drug offers fertility hope for women with obesity
Common drug offers fertility hope for women with obesity
Researchers may have found a solution to improving fertility in women with obesity, following a successful trial in mice using diabetes medication to reduce blood glucose levels. The University of Queensland study found the common type 2 diabetes medication, Dapagliflozin, altered reproductive hormones in obese mice, and could be the key to improving fertility in humans.

Life Sciences - Pharmacology - 25.05.2022
Study identifies how the brain links memories
Study identifies how the brain links memories
Our brains rarely record single memories. Instead, they store memories in groups so that the recollection of one significant memory triggers the recall of others that are connected chronologically. As we age, however, our brains gradually lose this ability to link related memories. Now, UCLA researchers have discovered a key molecular mechanism behind this memory linking.

Health - Pharmacology - 25.05.2022
Blood biomarker predicts complicated Crohn's disease years before diagnosis: Study
Blood biomarker predicts complicated Crohn’s disease years before diagnosis: Study
An international team led by a University of Toronto researcher has found that an antibody in the blood predicts severe Crohn's disease and is detectable up to seven years prior to disease diagnosis. Crohn's disease is a chronic inflammatory condition of the intestine for which simple and effective biomarkers prior to diagnosis are lacking.

Health - Pharmacology - 24.05.2022
Population-scale study highlights ongoing risk of COVID-19 in some cancer patients despite vaccination
Population-scale study highlights ongoing risk of COVID-19 in some cancer patients despite vaccination
The UK Coronavirus Cancer Evaluation Project has delivered the world's largest analysis of the effect of COVID-19 vaccination on people with cancer.

Life Sciences - Pharmacology - 24.05.2022
Molecular light switches provide insights into the central nervous system
Fluorescent dyes, such as those used in discotheques with black lights or from forensic crime-scene searches for blood traces, play an important role in pharmaceutical research in particular. They can be used to visualize biological structures in fluids, cells or tissues. A team led by neuropharmacologist Margot Ernst from the Medical University of Vienna and theoretical chemist Leticia González from the University of Vienna have conducted a study to investigate the mechanism of a fluorescent dye for neuroscience.

Health - Pharmacology - 24.05.2022
During general anaesthesia, 1 in 10 people may be ’conscious’ following intubation
An international study has found around 1 in 10 participants under planned general anaesthesia were able to respond to commands. Importantly, no subjects remembered the commands after surgery. Researchers say the study sheds light on a medical phenomenon known as connected consciousness. 'Connected consciousness' occurs when people under general anaesthetic are able to respond to outside stimuli such as pain but may not be able to recall the event afterwards.

Health - Pharmacology - 24.05.2022
COVID vaccines do not impact fertility or pregnancy outcomes
Women who received mRNA vaccines against the COVID-19 virus did not produce more of an antibody that had been theorized to reduce fertility, Yale School of Medicine researchers report in a new study. In addition, the research team found pregnant mice injected with mRNA vaccines suffered no side effects and produced normal offspring, according to the research, published May 24 in the journal PLOS Biology.

Health - Pharmacology - 23.05.2022
Heart Inflammation found in 1 in 8 patients after hospitalisation with COVID-19
One in eight people who were hospitalised with COVID-19 between May 2020 and March 2021 were later diagnosed with myocarditis, or heart inflammation, according to major new research into the clinical long-term effects of COVID-19. The largest study of its kind to date was led by the University of Glasgow in collaboration with NHS Greater Glasgow and Clyde (NHS GGC), and followed for one year, in real time, 159 patients after they were hospitalised with COVID-19.

Health - Pharmacology - 19.05.2022
New reporting guidelines developed to improve AI in healthcare settings
New reporting guidelines, jointly published and the BMJ by Oxford researchers, will ensure that early studies on using Artificial Intelligence (AI) to treat real patients will give researchers the information needed to develop AI systems safely and effectively. Artificial Intelligence in medicine has shown promising results in numerous simulation studies, but very few AI systems have yet been used in patient care.

Health - Pharmacology - 19.05.2022
New non-invasive method of risk assessment in liver disease
In a recent study, an interdisciplinary research team from MedUni Vienna showed that functional magnetic resonance imaging (fMRI) can be used as a non-invasive method for predicting complications in chronic liver disease. The scientists combined a simple risk stratification system developed at MedUni Vienna - the functional liver imaging score (FLIS) - with splenic diameter.

Health - Pharmacology - 19.05.2022
Study tests link between common blood pressure pills and breast cancer
Curtin researchers will examine if the long-term use of a popular blood pressure medication increased the risk of breast cancer in almost 200,000 women as part of a new project supported by the Federal Government. The new research, awarded an NHMRC Clinical Trials and Cohort Studies Grant, will investigate the link between the long-term use of calcium channel blockers and the risk of breast cancer by examining three internationally renowned Australian and Dutch longitudinal cohorts using state-of-the-art analytical techniques, which have not been used in this area before.

Health - Pharmacology - 18.05.2022
Antibiotics given shortly before caesarean birth not linked to asthma and eczema in young children
Antibiotics given to women before a caesarean birth have no effect on the risk of early childhood conditions, such as asthma or eczema, suggests a study by researchers at the Universities of Warwick and Birmingham. The research, published today (18 May 2022) in The BMJ, and funded by the National Institute for Health and Care Research, provides further evidence to support recommendations made by the National Institute for Health and Care Excellence (NICE).

Health - Pharmacology - 18.05.2022
Significant gains from computer-based depression treatment
Significant gains from computer-based depression treatment
A new international collaborative study, involving multiple institutions including Western University, has found computer-based cognitive behavioural therapy (CCBT) has significantly greater impact in treating depression among adults than treatment as usual (TAU).

Health - Pharmacology - 18.05.2022
New research may explain unexpected effects of common painkillers
New research may explain unexpected effects of common painkillers
Non-steroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen and aspirin are widely used to treat pain and inflammation. But even at similar doses, different NSAIDs can have unexpected and unexplained effects on many diseases, including heart disease and cancer. Now, a new Yale-led study has uncovered a previously unknown process by which some NSAIDs affect the body.

Health - Pharmacology - 16.05.2022
In osteoarthritis of the knee, the same treatment does not work for everyone. How to know when to operate?
Researchers from the UPF BCN MedTech research unit, the IMIM-Hospital del Mar and the Hospital del Mar have studied the relationship between clinical treatment options for osteoarthritis of the knee and the functionality, speed and forces involved in each patient's stride. The results reveal that two patients with the same symptoms may need different treatment depending on their age and body mass index.
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