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Pharmacology - Health - 13.05.2022
Pharmacists at Higher Risk of Suicide than General Population
The pandemic put a spotlight on mental health and burnout within health care professions, but emerging research reveals these issues have been affecting health care workers for years, with suicide rates notably high among physicians and nurses. But until now, less was known about the mental health of pharmacists.

Pharmacology - Health - 13.05.2022
'Nanobodies' from llamas could yield targeted treatment methods for humans
’Nanobodies’ from llamas could yield targeted treatment methods for humans
'Nanobodies' from llamas could yield cell-specific medications for humans The nanobodies could help target issues such as irregular heart rhythms and could help prevent and control seizures In "proof of concept" experiments with mouse and human cells and tissues, Johns Hopkins Medicine researchers say they have designed tiny proteins, called nanobodies, derived from llama antibodies, that could potentially be used to deliver targeted medicines to human muscle cells.

Health - Pharmacology - 11.05.2022
The combination makes the difference: New therapeutic approach against breast cancer
The combination makes the difference: New therapeutic approach against breast cancer
Some breast tumors with certain genetic alterations are difficult to treat using existing therapies. Researchers at the University of Basel have now discovered an approach that involves a toxic combination with a second target gene in order to kill the abnormal cells. The first clinical trials could be starting soon.

Health - Pharmacology - 11.05.2022
Discovery reveals blocking inflammation may lead to chronic pain
Discovery reveals blocking inflammation may lead to chronic pain
Using anti-inflammatory drugs and steroids to relieve pain could increase the chances of developing chronic pain, according to researchers from McGill University and colleagues in Italy. Their research puts into question conventional practices used to alleviate pain. Normal recovery from a painful injury involves inflammation and blocking that inflammation with drugs could lead to harder-to-treat pain.

Pharmacology - Health - 10.05.2022
Why Australians take medicinal cannabis
Of the 248,000 scripts approved for Australians since the inception of the national medicinal cannabis scheme in 2016, many related to conditions for which the drug has limited evidence of efficacy, a new University of Sydney study shows. The first in-depth study of Australia's medicinal cannabis program, which began in 2016, shows the drug is being increasingly prescribed for various conditions.

Pharmacology - Health - 09.05.2022
Lymphomas: new model developed at the IOR against drug resistance
Lymphomas: new model developed at the IOR against drug resistance
The Lymphoma Genomics group, directed by Prof. Francesco Bertoni at the Institute of Oncology Research (IOR, affiliated to USI and member of Bios+), identified a new mechanism behind the resistance to the drug idelalisib, used in the treatment of patients with follicular lymphoma and marginal zone lymphoma.

Health - Pharmacology - 06.05.2022
Targeting Molecular Pathway that Causes Pulmonary Arterial Hypertension
UC San Diego researchers describe imbalance of opposing cell signals that cause deadly disease, and how a novel monoclonal antibody therapy might treat or prevent it Pulmonary arterial hypertension (PAH) is a type of high blood pressure in the lungs, in which blood vessels are narrowed, blocked or destroyed, causing the heart to work harder and, in time, result in cardiac weakness and failure.

Pharmacology - Health - 06.05.2022
Scientists closer to outsmarting malaria parasites
Researchers from The Australian National University (ANU) have discovered why malaria parasites are vulnerable to some drug ther apies but resistant to others , offering scientists another piece of the puzzle in the global fight against the disease. The ANU team has characterised two malaria proteins , known as PfMDR1 and PfCRT , t'hat work together to transport drugs away from areas where the y exert their killing effect and concentrate them in "safe zones" that ultimately rend er the treatment s'ineffective.

Pharmacology - Health - 05.05.2022
Small changes - but essential! How peptides are recognised in receptors
Small changes - but essential! How peptides are recognised in receptors
Researchers discover molecular mechanisms of signal recognition of the neuropeptide system The human body consists of trillions of cells that constantly communicate with each other. A central role in this communication process is played by receptor proteins on the cell surface. Since they often serve as drug targets, they have been the subject of intensive research.

Health - Pharmacology - 05.05.2022
Digital health support systems help improve health for people with breast cancer
A study has found people with breast cancer who received ongoing support through digital resources such as websites and mobile apps reported improved quality of life, and less stress and fatigue. People with breast cancer who accessed digital support systems such as websites and mobile apps overall found it was a valuable resource in between medical appointments, making them more confident in managing their health and improving their quality of life.

Life Sciences - Pharmacology - 05.05.2022
A paper of the Universitat de València and IIS La Fe about stem cells differentiation to hepatocytes appears on the cover of the Journal of Proteome Research
A paper of the Universitat de València and IIS La Fe about stem cells differentiation to hepatocytes appears on the cover of the Journal of Proteome Research
The research team of the Mixed Unit Universitat de Valéncia-IIS La Fe of Experimental Hepatology and Hepatic Transplantation has published a paper in the Journal of Proteome Research, a peer-reviewed scientific journal of the American Chemical Society.

Environment - Pharmacology - 05.05.2022
Our lifestyles are key contributors to river pollution - here is how social prescribing can help
Our lifestyles are key contributors to river pollution - here is how social prescribing can help
Home and lifestyle activities are major contributors to water quality. Social interventions may provide the most sustainable solution. Household and lifestyle activities are key contributors to water quality, according to new research from the University of Bath. Social interventions - such as social prescribing - may provide a more sustainable solution to this problem than improvements to wastewater treatment processes.

Health - Pharmacology - 04.05.2022
Influenza: A New Avenue for Developing Innovative Treatments
Influenza: A New Avenue for Developing Innovative Treatments
Seasonal influenza is a major public health issue because it continues to remain associated with considerable mortality, particularly among people who are elderly, immunocompromised, or both. It also has a significant socioeconomic cost. With vaccination and current treatments still being of limited efficacy, research teams are trying to develop new therapeutic approaches.

Health - Pharmacology - 04.05.2022
Krill oil may be beneficial to muscle function and size, in people over 65
Krill oil may be beneficial to muscle function and size in healthy people over the age of 65, according to new research. The study - led by the University of Glasgow's Institute of Cardiovascular and Medical Sciences (ICAMS) and published in Clinical Nutrition - found that krill oil supplementation of four grams per day could have beneficial effects on skeletal muscle function and size in this age group.

Pharmacology - Health - 03.05.2022
Antibiotics impact gut microbiome and antimicrobial resistance
Antibiotics impact gut microbiome and antimicrobial resistance
Antibiotics are commonly used to treat infections and ensure the safety of surgical procedures. However, their overuse has led to the emergence and spread of resistant bacteria, resulting in an -arms race- whereby ever more potent drugs are becoming a necessity.

Environment - Pharmacology - 02.05.2022
Bioassays evaluate ozonation and post-treatment of wastewater
Bioassays evaluate ozonation and post-treatment of wastewater
Through wastewater, rivers and lakes are polluted with numerous micropollutants which originate from care products and pharmaceuticals, among other things. The Waters Protection Act therefore aims to expand Swiss wastewater treatment plants (WWTP) with the addition of a further treatment step. In pilot tests, two processes have proven particularly successful in the removal of trace substances: ozonation and treatment with activated carbon.

Health - Pharmacology - 02.05.2022
Catching COVID-19 during pregnancy increases risk of hospitalization, premature birth: national study
Catching COVID-19 during pregnancy increases risk of hospitalization, premature birth: national study
Science, Health & Technology Brett Goldhawk As Canada faces a sixth wave of COVID-19 infections, researchers at the UBC faculty of medicine are urging people who are pregnant to remain vigilant based on data from Canada's first national, peer-reviewed study on COVID-19 in pregnancy. The findings, published today in JAMA , show that pregnant people who catch COVID-19 are at greater risk of being hospitalized, being admitted to intensive care units (ICUs) and experiencing an early birth.

Health - Pharmacology - 28.04.2022
Vaccination campaign messages often prove ineffective
Vaccination campaign messages often prove ineffective
Conventional vaccination campaign messages often miss their targets. A study in eight European countries shows that information on the benefits of vaccines can even reduce the willingness to get immunized. The researchers also looked into the factors that influenced the impact of messages, including low health literacy.

Health - Pharmacology - 28.04.2022
New drug shows promise slowing tumour growth in some hard-to-treat cancers
New drug shows promise slowing tumour growth in some hard-to-treat cancers
Scientists at Sinai Health and the University of Toronto say a new drug designed to block an enzyme essential for the survival of certain cancer cells shows promise in curbing tumour growth. The preclinical findings,  published this month in the journal  Nature , describe a new drug designed with CRISPR-Cas9 gene-editing technology in the lab of  Daniel Durocher , a senior investigator at Sinai Health's  Lunenfeld-Tanenbaum Research Institute  (LTRI) and a professor of molecular genetics in University of Toronto's Temerty Faculty of Medicine.

Health - Pharmacology - 28.04.2022
Antibodies fighting original virus may be weaker against omicron
Antibodies fighting original virus may be weaker against omicron
A study of vaccinated individuals with breakthrough COVID-19 infection showed that their antibodies, while effective at stopping original strain of virus, was less effective at preventing infection by omicron variant New research may explain why so many vaccinated and boosted individuals experienced breakthrough coronavirus infections caused by the omicron variant.
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