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Health - Pharmacology - 05.07.2022
How Omicron dodges the immune system
How Omicron dodges the immune system
By comparing the neutralisation capacity induced by the different variants of SARS-CoV-2, a team from the UNIGE and the HUG reveals the exceptional capacity of Omicron to evade our immunity. The current wave of COVID-19 highlights a particularly high risk of reinfection by the Omicron variant of SARS-CoV-2.

Pharmacology - Health - 29.06.2022
Artificial intelligence techniques used to obtain antibiotic resistance patterns
The Universidad Carlos III de Madrid (UC3M) is conducting research that analyses antibiotic resistance patterns with the aim of finding trends that can help decide which treatment to apply to each type of patient and stop the spread of bacteria. This study, recently published in the scientific journal Nature Communications, has been carried out together with the University of Exeter, the University of Birmingham (both in the United Kingdom) and the Westmead Hospital in Sydney (Australia).

Health - Pharmacology - 29.06.2022
Later diagnosis of children with Wilms tumours in the UK leads to lower survival chances
Children in the UK and Republic of Ireland who are diagnosed with Wilms tumour - the most common children's kidney cancer - are less likely to survive without relapse than those in Germany and France due to later diagnosis, finds a new study led by UCL researchers. The study, published in JCO Global Oncology , compared tumour size and stage of cancer at diagnosis with survival chances of 3,176 children with Wilms tumour.

Health - Pharmacology - 29.06.2022
Hormone-blocking breakthrough helps combat skin cancer recurrence
Hormone-blocking breakthrough helps combat skin cancer recurrence
A Monash University researcher has helped discover how to reduce the recurrence of skin cancer tumours by blocking a naturally-occurring hormone that causes drug resistance in melanoma cells. Studies showed that by blocking androgens - the 'male' sex hormones - with the drug enzalutamide, melanoma cells were more sensitive to drugs designed to inhibit cancer growth.

Health - Pharmacology - 28.06.2022
Highly Effective Memory B Cells Localized in the Lungs
How can we increase the efficacy of vaccines used to protect against viral respiratory diseases such as influenza and COVID-19? Scientists from Inserm, CNRS and Aix-Marseille Université at the Center of Immunology Marseille-Luminy are opening up new prospects in the field, with the triggering of memory B cells directly in the lungs looking to be a promising avenue.

Health - Pharmacology - 28.06.2022
Highly antibiotic-resistant strain of MRSA that arose in pigs can jump to humans
A new study has found that a highly antibiotic-resistant strain of the superbug MRSA - methicillin resistant Staphylococcus aureus - has emerged in livestock in the last 50 years, probably due to widespread antibiotic use in pig farming. Cases of livestock-associated MRSA in humans are still only a small fraction of all MRSA cases in human populations, but the fact that they-re increasing is a worrying sign.

Pharmacology - 27.06.2022
Opioid poisoning on the rise
Researchers at ETH have shown that cases of opioid poisoning and the prescription of opioids have increased sharply in Switzerland over the past 20 years. Although the situation is not as serious as in North America, the risk should not be underestimated. Since the early 2000-s the US has been in the grip of an opioid crisis that has been exacerbated by the Covid pandemic - in 2021, more than 100,000 people died of an opioid overdose in the country.

Health - Pharmacology - 27.06.2022
Nitric Oxide Does Not Improve Babies' Recovery after Heart Surgery
Nitric Oxide Does Not Improve Babies’ Recovery after Heart Surgery
Infants undergoing heart surgery are connected to a heart-lung machine and given nitric oxide as an anti-inflammatory. Researchers from the Universities of Zurich and Queensland have now conducted the world's largest study of its kind, showing that using nitric oxide does not improve children's recovery after surgery.

Health - Pharmacology - 23.06.2022
New hope to stop spread of antibiotic resistance
A new path to help stop the spread of antibiotic resistance has been uncovered by a team led by UCL and Birkbeck researchers, in a move that could impact the lives of millions globally. The pioneering research the structure of the transport apparatus that enables the spread of antibiotic resistant genes between bacteria.

Pharmacology - Health - 23.06.2022
Cannabis self-medication: a solution that may create problems
Cannabis self-medication: a solution that may create problems
Even if the evidence of the effectiveness of cannabis is still very scarce, Quebecers are self-prescribing products from this plant for health problems ranging from pain to shyness Anxiety, depression, insomnia, shyness, migraines, muscle spasms, pain, loss of appetite, loss of libido. These are some of the health problems for which Quebecers self-prescribe cannabis, even though no reliable scientific study has yet demonstrated its effectiveness for these uses.

Pharmacology - Health - 22.06.2022
Mugwort allergy: MedUni Vienna study creates basis for vaccine
A research team at MedUni Vienna has discovered key mechanisms of allergy to pollen from the common weed mugwort, thereby also laying the foundation for the development of the world's first vaccine. Mugwort (Artemisia vulgaris) poses a serious problem for allergic individuals in our latitudes from July through to September.

Health - Pharmacology - 21.06.2022
Plant Virus Plus Immune Cell-Activating Antibody Clear Colon Cancer in Mice, Prevent Recurrence
A new combination therapy to combat cancer could one day consist of a plant virus and an antibody that activates the immune system's "natural killer" cells, shows a study by researchers at the University of California San Diego. In mouse models of colon cancer, the combination therapy eliminated all tumors and prevented their recurrence, which in turn resulted in 100% survival.

Health - Pharmacology - 21.06.2022
New blood biomarker identified for status of fatty liver disease
New blood biomarker identified for status of fatty liver disease
A MedUni Vienna study team has identified the role of a specific subtype of macrophages (white blood cells) in progressive non-alcoholic fatty liver disease. As part of the immune system, these cells have a protective function against fibrosis and liver cirrhosis. At the same time, they are useful as biomarkers of liver disease progression as they can be measured by a blood test.

Health - Pharmacology - 17.06.2022
Progesterone altering drug could reduce risk of aggressive breast cancer
New research co-led by scientists at UCL, found that existing drugs modifying the effect of the hormone progesterone, such as mifepristone, could reduce the risk of aggressive "triple negative" breast cancer in women with an alteration of the BRCA1 gene. Triple-negative breast cancer (TNBC) is most common in women who have a BRCA1 mutation and this type of cancer affects 13 in every 100,000 women.

Pharmacology - Social Sciences - 16.06.2022
New nano-gel to protect children receiving chemotherapy from hearing loss
Curtin researchers will test a new nano-gel they have created to protect children receiving chemotherapy treatment from the common side effect of hearing loss, as part of a new project with Ear Science Institute Australia and supported by funding from the Channel 7 Telethon Trust. Lead researcher Associate Professor Hani Al-Salami, from the Curtin Health Innovation Research Institute (CHIRI) based at Curtin University, said 90 per cent of children survive cancer but about half will have some degree of permanent hearing due to toxic effects of chemotherapy drugs.

Health - Pharmacology - 16.06.2022
Breakthrough study of hormone 'crosstalk' in breast cancer
Breakthrough study of hormone ’crosstalk’ in breast cancer
Scientists led by EPFL have successfully engrafted breast cancer cells on mice, allowing them to study in vivo the cross-talk between the estrogen and progesterone receptors that hampers hormone therapies. Their findings suggest that endocrine therapy may need to be personalized, and that abrogating progesterone receptor expression can be a therapeutic option.

Health - Pharmacology - 15.06.2022
Factors causing low COVID vaccination rates have spilled over to flu vaccine rates in parts of U.S
A new study by UCLA researchers reveals that adult flu vaccination rates have declined in U.S. states where COVID-19 vaccination rates are also low. The research suggests declining trust in public health, indicating that COVID-19 vaccination behavior has spilled over to flu vaccination behavior.

Health - Pharmacology - 15.06.2022
Covid-19: chronic liver disease patients at high risk of liver failure and bile duct damage
Patients with chronic liver disease may suffer hepatic complications as a result of severe Covid-19. A study conducted by a research team led by Lukas Hartl, Thomas Reiberger and Michael Trauner from the Division of Gastroenterology and Hepatology of MedUni Vienna and University Hospital Vienna found that a rise in cholestasis parameters and subsequent damage to the bile ducts, so-called secondary sclerosing cholangitis (SSC), develops with striking frequency in patients with pre-existing liver disease.

Health - Pharmacology - 15.06.2022
Opioid use disorder: flexible treatment at home proves effective
Opioid use disorder: flexible treatment at home proves effective
A pan-Canadian team announces initial results of the national OPTIMA study comparing the efficacy of two models of care for treating opioid use disorder. Did you know that more than 26,500 Canadians died from opioid intoxication between January 2016 and September 2021? Or that more than 350,000 people who used drugs containing opioids to relieve their pain did so problematically? In Quebec alone, 339 people died from opioid intoxication between January and September 2021, according to the latest data from the Public Health Agency of Canada.

Pharmacology - Health - 15.06.2022
Minorities saw steeper drop in access to opioid use disorder meds during pandemic
Relative to white patients, racial and ethnic groups saw a sharper decline in access to medicines to treat opioid use disorder during the early stages of the COVID-19 pandemic-intensifying pre-pandemic disparities, says a University of Michigan researcher. "We found that COVID-19 was associated with widened racial and ethnic disparities in buprenorphine, the most common medication to treat opioid use disorder,” said Thuy Nguyen , research assistant professor at the U-M's School of Public Health and first author of the study published in JAMA Network Open.