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Results 21 - 40 of 217.

Health - Pharmacology - 27.05.2024
Multi-purpose mucus
Multi-purpose mucus
What mucins can do in medicine They are in our eyes, on our tongues, and in our stomachs: Protective layers of mucus, a slime consisting primarily of mucins. These are molecules which bind water to form a natural lubricant. Researchers at the Technical University of Munich (TUM) use them to develop coatings for contact lenses and intubation tubes, healing plasters for use on the tongue and intestines, and much more.

Pharmacology - Health - 27.05.2024
New therapy proven effective against rejection in kidney transplantation
New therapy proven effective against rejection in kidney transplantation
Antibody-mediated rejection (AMR) is one of the most common causes of kidney transplant failure. To date, however, no treatment has proven effective in combating this complication in the long term. As part of an international and multidisciplinary clinical study led by Georg Böhmig and Katharina Mayer, Clinical Division of Nephrology and Dialysis, Department of Medicine III at MedUni Vienna and University Hospital Vienna, a new therapeutic principle in transplant medicine has been found to be both safe and highly effective.

Health - Pharmacology - 24.05.2024
In stroke response, speed is key; Yale study reveals where delays are worst
In stroke response, speed is key; Yale study reveals where delays are worst
When it comes to stroke treatment, every minute counts. A new study identifies factors associated with treatment delays - and targets for intervention. When it comes to responding to a stroke, speed is a crucial factor; the longer it takes for someone experiencing a stroke to get to a hospital, the worse the outcome will be.

Health - Pharmacology - 23.05.2024
New approach to Epstein-Barr virus and resulting diseases
New approach to Epstein-Barr virus and resulting diseases
The Epstein-Barr virus can cause a spectrum of diseases, including a range of cancers. Emerging data now show that inhibition of a specific metabolic pathway in infected cells can diminish latent infection and therefore the risk of downstream disease, as reported by researchers from the University of Basel and the University Hospital Basel in the journal Science.

Pharmacology - 23.05.2024
New Study Highlights Significant Increases in Cannabis Use in US
A new study by a researcher at Carnegie Mellon University assessed cannabis use in the United States between 1979 and 2022, finding that a growing share of cannabis consumers report daily or near-daily use and that their numbers now exceed those of daily and near-daily alcohol drinkers. The study concludes that long-term trends in cannabis use parallel corresponding changes in policy over the same period.

Life Sciences - Pharmacology - 22.05.2024
Hallucinogenic mushrooms to treat alcohol addiction
Hallucinogenic mushrooms to treat alcohol addiction
A ground-breaking study conducted by INSERM's Groupe de Recherches sur l'Alcool et les Pharmacodépendances (GRAP) opens up new therapeutic perspectives for the treatment of alcohol addiction with psilocybin, the active compound in hallucinogenic mushrooms. Published in the scientific journal Brain , their work confirms the potential of psilocybin to combat alcohol addiction, while shedding light on the molecule's hitherto unknown mechanisms of action.

Health - Pharmacology - 22.05.2024
Gentler cell therapies for blood cancer
Researchers have developed an approach to -deleting- a blood system affected by leukemia while simultaneously building up a new, healthy system with donor blood stem cells. Writing in the journal Nature, the team reports on the promising results obtained in animal experiments and with human cells in the laboratory.

Health - Pharmacology - 21.05.2024
Could naked mole rats be the key to fighting cancer?
A ULB study reveals a new advance in our understanding of the immune system of the naked mole rat, opening up prospects for cellular immunotherapy of cancer . During the development of cancer, the immune system is able to exert antitumor activity thanks to natural killer (NK) cells and T lymphocytes.

Health - Pharmacology - 21.05.2024
Tuberculosis: a new lead for biomarkers to assess the risk of transmission
Tuberculosis is the second leading cause of death from infectious disease in the world after COVID-19. Scientists from INRAE and Inserm have discovered two subsets of neutrophils that play opposing roles in inflammatory responses to infection and could serve as biomarkers to identify individuals at risk of developing a contagious form of the disease.

Pharmacology - Health - 21.05.2024
Western-led analysis shows potential in new Alzheimer’s treatment
Alzheimer's disease is the most common cause of dementia, affecting more than 55 million people worldwide. Currently, the two main approaches for treatments to delay or slow its progression target the buildup of amyloid beta peptides - which form plaques in the spaces between nerve cells in the brain - and the buildup of tau protein, resulting in tangles which damage neurons.

Pharmacology - 20.05.2024
How beeswax could help families in warzones
Beeswax and local herbs could be crucial in helping families living in conflict zones store food, according to scientists from Cardiff University and Kharkiv Polytechnic Institute of National Technical University, Ukraine.

Pharmacology - Health - 20.05.2024
Contraception options should be given with oral retinoids to avoid serious harm to unborn babies
Prescription oral retinoids to treat acne are increasing in popularity. Concerningly, data reveals not enough precautions are being taken to protect women from the risk of serious congenital abnormalities if they fall pregnant while on this medication. Demands for oral retinoids to treat acne have nearly doubled in the last nine years, but a study has found contraception is being neglected for reproductive aged women taking these medications.

Health - Pharmacology - 16.05.2024
Pathoblockers, a Future Alternative to Antibiotics’
Researchers at Freie Universität Berlin and Charité - Universitätsmedizin Berlin "defanging" bacteria, rendering them harmless In most cases, antibiotics are a reliable form of protection against bacterial infections. They have saved billions of human lives since their introduction. This protection, however, is threatened by bacteria's resistance to classical antibiotics and by their aggressive pathogenicity.

Pharmacology - Life Sciences - 16.05.2024
A Second Chance for New Antibiotic Agent
Twenty years ago, a drug candidate was rejected due to its side effects. Researchers have now figured out how to potentially make a successor molecule more selective. An increasing number of bacteria have become resistant to many commonly used antibiotics. Researchers from Bochum have discovered a fresh opportunity for a potential active molecule whose predecessor was rejected: By studying its interaction with the bacterial target protein very precisely in three dimensions, they identified a previously undetected point of attack that could be targeted by this compound.

Health - Pharmacology - 16.05.2024
At the right time for tumours
By examining the immune modulations of tumours during the day, scientists from the University of Geneva and the LMU Munich are demonstrating their impact on the diagnosis and management of patients. The currently most promising anti-tumour treatments are immunotherapies, which aim to boost the action of the patients' immune system to fight cancer.

Pharmacology - 16.05.2024
Scientists brew killer bee beer
A new beer is being brewed by microbiologists, using extracts found in killer bees from Namibia. Scientists from Cardiff University have used brewer's yeast that resides in the gut microbiome of killer honeybees in Namibia and applied it to develop a unique craft beer. The Cardiff microbiologists originally visited Namibia as part of a project that unites Cardiff University and the University of Namibia for sustainable environmental development, when the scientists became interested in the Africanised honey bee - also known as the killer bee.

Pharmacology - Health - 15.05.2024
Study Paves the Way for an Active Agent Against Hepatitis E
A newly identified compound prevents a cellular enzyme from cleaving the virus particle. As a result, the virus can no longer infect cells. At present, there is no specific active substance against hepatitis E. As the disease kills 70,000 people every year, researchers are actively searching for one.

Health - Pharmacology - 14.05.2024
’Weight loss’ drug semaglutide linked to better heart health
The weight loss drug semaglutide delivers cardiovascular benefits irrespective of starting weight and amount of weight lost, according to preliminary findings from a UCL-led research team. The findings, presented at this year's European Congress on Obesity (ECO), suggest that even people with mild obesity or those not losing weight are likely to gain some cardiovascular advantage.

Health - Pharmacology - 13.05.2024
Birth by C-section more than doubles odds of measles vaccine failure
Researchers say it is vital that children born by caesarean section receive two doses of the measles vaccine for robust protection against the disease. A study by the University of Cambridge, UK, and Fudan University, China, has found that a single dose of the measles jab is up to 2.6 times more likely to be completely ineffective in children born by C-section, compared to those born naturally.

Health - Pharmacology - 13.05.2024
Limited efficacy of common local anaesthetic
Liposomal bupivacaine was launched on the market twelve years ago to provide long-lasting local control of pain. The medication is used as a local anaesthetic, particularly for orthopaedic operations. A research study by MedUni Vienna has now shown the limited effectiveness of the substance. The study has just been published in the journal "Anesthesiology", the peer-reviewed journal of the American Society of Anesthesiologists (ASA).