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Pharmacology - 05.04.2024
People make more patient decisions when shown the benefits first
People make more patient decisions when shown the benefits first
Science + Technology Focusing immediately on the benefits of waiting might help people improve their self-control Key takeways UCLA psychologists asked experiment participants to choose to receive $40 in seven days or $60 in 30 days, for example, under a variety of time constraints. The experiment showed that people tend to make more impulsive decisions if they think about time delays first, and more patient decisions if they think about the greater reward associated with waiting longer.

Health - Pharmacology - 04.04.2024
Stool transplantation shows promise for Parkinson's disease
Stool transplantation shows promise for Parkinson’s disease
Dr. Arnout Bruggeman (VIB-UGent-UZ Gent), Prof. Debby Laukens (UGent), Prof. Roosmarijn Vandenbroucke (VIB-UGent) en Prof. Patrick Santens (UZ Gent) Clinical study shows stool transplantation of healthy gut bacteria reduces Parkinson's disease symptoms. Parkinson's disease (PD) is a common neurodegenerative disease that affects millions worldwide.

Pharmacology - Health - 03.04.2024
New Discovery Unravels Malaria Invasion Mechanism
New Discovery Unravels Malaria Invasion Mechanism
A recent breakthrough sheds light on how the malaria parasite, Plasmodium falciparum, invades human red blood cells. The study, led by the Swiss Tropical and Public Health Institute (Swiss TPH) and Griffith University's Institute for Glycomics, reveals the role of a sugar called sialic acid in this invasion process.

Pharmacology - Health - 01.04.2024
New synthesis platform allows for rapid cancer drug synthesis and testing
New synthesis platform allows for rapid cancer drug synthesis and testing
Researchers have developed a new platform for the synthesis, analysis and testing of new compounds which may one day treat cancer The discovery of new compounds with pharmacological properties can be expensive and time-consuming. Therefore, there is an increasing interest in developing workflows that allow for the rapid synthesis and testing of multiple compounds in parallel.

Health - Pharmacology - 28.03.2024
TB vaccine may enable elimination of the disease in cattle by reducing its spread
Vaccination not only reduces the severity of TB in infected cattle, but reduces its spread in dairy herds by 89%, research finds. Our study suggests that vaccination not only reduces the progression of the disease, but that if vaccinated animals become infected, they are substantially less infectious to others.

Psychology - Pharmacology - 27.03.2024
People with depression see no immediate change from common GP assessment
People with depression see no immediate change from common GP assessment
But PHQ-9 questionnaire used to monitor primary care patients did reveal benefits across six months A commonly used questionnaire adopted by GPs to monitor the treatment of depression does not provide any immediate benefits to patients, a new study has found. Primary care researchers testing the PHQ-9 assessment, which measures the severity of depression, found it did nothing to improve people's symptoms after 12 weeks.

Health - Pharmacology - 27.03.2024
How some heart medications impact gut health
How some heart medications impact gut health
UCalgary study finds certain medications decrease diversity and beneficial microorganisms found in the gut, which may affect overall health Our intestines house trillions of microorganisms known as the gut microbiota. These microorganisms are important players in both drug metabolism and certain conditions like high blood pressure, coronary artery disease and diabetes.

Health - Pharmacology - 27.03.2024
Locums and permanent GPs equally safe, study reassures patients
There is no evidence that locum doctors are less clinically competent or practice less safely than permanent doctors, a study in England led by University of Manchester researchers has shown. Some differences in practice and performance of locum and permanent GPs were found, however the researchers suggest they are likely to be shaped by the organisational setting and systems within which they work.

Pharmacology - Economics - 26.03.2024
How to prevent social desirability bias in surveys
Marketing researcher Rik Pieters has developed, together with colleagues from other universities, a new, indirect questioning technique to improve the chance that people answer truthfully. The technique can be used, for instance, in conducting surveys or in making policies. Chances are that people tend to give socially desirable answers to direct survey questions on sensitive subjects, like watching porn, smoking during pregnancy, theft in the supermarket or illegal acquisition of prescription drugs.

Health - Pharmacology - 26.03.2024
Gene discovery offers new hope for Aussies living with chronic skin disease´┐╝
Gene discovery offers new hope for Aussies living with chronic skin disease´┐╝
Scientists from The Australian National University (ANU) have discovered a gene mutation is responsible for causing psoriasis - a chronic inflammatory skin disease that causes patients to develop red, scaly and itchy patches across their body. According to ANU researcher Dr Chelisa Cardinez, if two copies of this mutated gene (known as IKBKB) are present, patients with psoriasis may go on to develop psoriatic arthritis, leaving them with joint pain, stiffness and swelling.

Pharmacology - Health - 26.03.2024
Clinical trial shows rheumatoid arthritis drug could prevent disease
A drug used to treat rheumatoid arthritis could also prevent the disease in individuals deemed to be at risk. Results from a Phase 2b clinical trial, published in The Lancet by a team led by King's College London and involving Birmingham researchers, provides hope for arthritis sufferers after it showed that the biologic drug abatacept reduces progression to this agonising chronic inflammatory disease.

Pharmacology - Health - 25.03.2024
QR codes improve medication adherence
QR codes improve medication adherence
Waterloo Pharmacy researchers collaborate with QRxDigital to make prescriptions easier to understand Being able to understand the medications you take should be a given. However, many people struggle to understand what to expect from the medications they're taking and how to take them effectively. Waterloo's clinical associate professor, Dr. Tejal Patel, has teamed up with QRxDigital to include QR codes on medication bottles that link to an instructional video that patients can view at home.

Health - Pharmacology - 25.03.2024
Progress made in understanding Crohn’s disease
Crohn's disease is a chronic inflammatory bowel disease that is sometimes insufficiently controlled by immunosuppressive therapies with a subsequent need for surgical removal of affected bowel segments. By analysing draining mesenteric lymph nodes of affected small intestinal segments of patients who had required surgery, a research team led by Lukas Unger from MedUni Vienna identified immune responses that improve our understanding of the disease.

Health - Pharmacology - 22.03.2024
Cervical cancer: immunotherapy proven to improve prognosis
Cervical cancer: immunotherapy proven to improve prognosis
Since 1999, the standard treatment for locally advanced cervical cancer has consisted of external radiotherapy followed by chemotherapy and brachytherapy. As the prognosis for patients is still poor in many cases despite these measures, intensive research is being conducted into new options. In a large-scale clinical trial, an international team involving MedUni Vienna has shown that the immunotherapeutic agent pembrolizumab in combination with chemoradiotherapy leads to a statistically significant improvement compared to chemoradiotherapy alone.

Health - Pharmacology - 21.03.2024
Kinder test could improve diagnosis of womb cancer
A simple, safe and accurate test that identifies women with womb cancer from a sample taken from the vagina has been developed by clinician scientists from The University of Manchester. The research, published in the journal Ebiomedicine, part of the Lancet Discovery Science, reports that the test has over 95% accuracy in identifying post-menopausal women with cancer as the cause of their bleeding, and is more accurate than current methods.

Pharmacology - Health - 21.03.2024
Healing eyes with contact lenses
Healing eyes with contact lenses
Patented bandage contact lens material could release drugs as needed to help eye abrasions heal faster A cross-disciplinary University of Waterloo team has developed a new contact lens material that could act as a bandage for corneal wounds while releasing drugs in a controlled manner to help the eye heal faster.

Health - Pharmacology - 21.03.2024
An Immunotherapy to Overcome Resistant Leukemia
An Immunotherapy to Overcome Resistant Leukemia
Researchers at the University of Zurich and the University Hospital Zurich have discovered that a specific mutation in the cancer cells of an aggressive type of blood cancer can prevent novel immunotherapies such as CAR T-cell therapy from working. Their study also explains why the cancer cells are resistant and how this resistance can be overcome: through concomitant pharmacotherapy or genetically improved CAR T-cells.

Health - Pharmacology - 21.03.2024
Results for: UCalgary researchers investigate the science of psilocybin-assisted treatment for alcohol use disorder
Results for: UCalgary researchers investigate the science of psilocybin-assisted treatment for alcohol use disorder
UCalgary researchers investigate the science of psilocybin-assisted treatment for alcohol use disorder Clinical trial to explore potential of psychedelics combined with therapy to help someone reduce or stop drinking University of Calgary researchers are about to conduct the largest single-site clinical trial of its kind in Canada to find out whether combining a known therapy with psychedelics could be a viable treatment for alcohol use disorder (AUD).

Health - Pharmacology - 19.03.2024
Fighting heart attack down to the smallest vessels
Fighting heart attack down to the smallest vessels
Researchers in Bern have co-developed and tested a new method to combat the blockage of tiny coronary arteries after a heart attack. The new approach, born from a cooperation of engineers, clinicians, and industry, offers a treatment option to prevent the death of heart tissue after a heart attack, responsible for poor long-term patient health.

Health - Pharmacology - 18.03.2024
New research could help doctors ’see’ bowel cancer
Imaging technology could provide a ground-breaking new approach for diagnosing and treating bowel cancer patients, thanks to Cancer Research scientists in Glasgow. Biopsies are currently used to diagnose bowel cancer but require an invasive procedure which offers risks, such as potential infection, and are unable to capture an entire picture of what is happening in a patient's bowel.