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Pharmacology - Health - 25.01.2022

Use of Alzheimer’s drug aducanumab raises concerns about Medicare spending
FINDINGS A UCLA-led cost analysis of the controversial new Alzheimer's disease drug aducanumab shows that ancillary care services, such as additional MRIs and neurologist visits to monitor the potential brain swelling and bleeding associated with the medication, account for nearly 20% of total Medicare costs related to the drug, or $6,564 per patient per year.

Health - Pharmacology - 24.01.2022

New antimicrobial therapeutics to fight superbugs
Researchers from Monash University have discovered a potential new way to prevent antibiotic resistance and reduce antibiotic intake. The World Health Organisation (WHO) has declared antimicrobial resistance to be among the top 10 global public health threats. Antimicrobial resistance occurs when pathogens (bacteria, viruses, fungi and parasites) change over time and no longer respond to medicines, consequently infections become increasingly difficult or impossible to treat.

Health - Pharmacology - 20.01.2022

More than a third of care home residents caught Covid-19 in early waves of pandemic
More than a third of care home residents and a quarter of care home staff in England showed evidence of infection with SARS-CoV-2 during the first two waves of the pandemic, according to a new study led by UCL researchers. The study, published in The Lancet Healthy Longevity , looked at blood samples from nearly 5,000 residents (with a median age of 87) and staff (with a median age of 48) at 201 care homes across England between June 2020 and May 2021.

Pharmacology - Health - 20.01.2022

Vaccine used in much of the world no match for omicron variant
Millions of people around the world have received two shots of Sinovac, a Chinese-manufactured inactive vaccine that is used in 48 countries to help reduce transmission rates of COVID-19. However, those vaccinations alone are of no help against the widely circulating omicron variant, shows a new study by researchers at Yale and the Dominican Republic.

Pharmacology - Health - 19.01.2022

New blood cancer gene defect can be treated with existing drugs
Share this page Share on Twitter Share on facebook Share on linkedin Share on email A defective gene normally found in blood cancers could be treated with drugs already available for cancers with similar gene defects, scientists at the University of Birmingham and Queen's University Belfast have revealed.

Pharmacology - Health - 18.01.2022

New Tool Assesses Evolutionary Risks of Antibiotics
Researchers developed a mathematical model that can help doctors choose antibiotics that minimize drug resistance Bacteria have dangerously evolved to thwart many of the medicines that were designed to kill them. As a result, a growing antibiotic resistance crisis is responsible for more than 700,000 deaths each year, emerging as one of the world's most pressing health issues.

Health - Pharmacology - 18.01.2022

’Off target’ effects of drugs used for autoimmune disorders needs better treatment strategy
New therapies for autoimmune rheumatic diseases (AIRDs) that are designed to better regulate lipid (fat) metabolism, could significantly reduce the harmful side-effects caused by conventional treatments, finds a new large-scale review led by UCL researchers. AIRDs affect millions globally and include rheumatoid arthritis, lupus and Sjögren's syndrome - all with high rates of morbidity.

Pharmacology - Environment - 17.01.2022

Researchers use AI to analyze tweets debating vaccination and climate change
Preparing for an online start to the winter term: for more information. Analyzing roughly 87 million tweets, researchers found sentiments around climate change to be uniform, but not so for vaccination Using artificial intelligence (AI) researchers have found that between 2007 and 2016 online sentiments around climate change were uniform, but this was not the case with vaccination.

Health - Pharmacology - 17.01.2022

Increasing the capacity of the immune system to kill cancer cells
UdeM cancer specialist André Veillette and his team at the IRCM unveil a promising approach using molecules found in macophages. Awakening the immune system's instinct for destroying cancer, using two molecules located on the surface of macrophages: that's the promising avenue opening up from recent laboratory work of Dr. André Veillette.

Health - Pharmacology - 14.01.2022

Australians are living longer from lockdowns
Pandemic restrictions have led to longer life expectancy for Australians, a new study from The Australian National University (ANU) has found.    A silver lining to seemingly endless days in lockdown is that Australians' life expectancy jumped in 2020. Instead of the expected average annual increase in longevity of 0.09-0.14 years seen from 2015 to 2019, researchers found an increase of 0.7 years from 2019 to 2020 for both females and males.

Health - Pharmacology - 14.01.2022

New dual benefit mode of action for a drug candidate to fight Covid-19
A research team led by Prof. Stephan Ludwig, a virologist at the Institute of Virology at the University of Münster, has found a new dual attack mode of action while working on the development of a drug candidate against SARS-CoV-2 infections. This could constitute the basis for a broadly effective drug to fight Covid 19.

Pharmacology - Health - 14.01.2022

Scientists uncover ’resistance gene’ in deadly E. coli
Scientists have pinpointed a gene that helps deadly E. coli bacteria evade antibiotics, potentially leading to better treatments for millions of people worldwide. The University of Queensland-led study found a particular form of the bacteria - E. coli ST131 - had a previously unnoticed gene that made it highly resistant to commonly prescribed antibiotics.

Pharmacology - Life Sciences - 13.01.2022

Promising novel treatment for Dry Eye Disease revealed by new research
The University of Manchester, Seoul National University College of Medicine and Link Biologics Limited today announced that promising preclinical data on the treatment of Dry Eye Disease using a novel protein biological drug, Link_TSG6, have been published in the peer-reviewed journal, Ocular Surface .

Health - Pharmacology - 13.01.2022

Computational Models Move Researchers Closer to Tuberculosis Vaccine
Expanse Supercomputer Spotlights Role of Unstable Cells in Response to Infection According to a 2021 World Health Organization report , the global COVID-19 pandemic caused an increase in tuberculosis (TB) deaths - 1.5 million in 2020 versus 1.4 million in 2019 - due to a lack of efficient diagnosis and treatment.

Health - Pharmacology - 13.01.2022

’It may be possible to prevent MS by means of vaccination.’
A large-scale study in the scientific journal Science reveals that the Epstein-Barr virus responsible for causing glandular fever is involved in the development of multiple sclerosis. Professor Jens Kuhle, who participated in the project, summarizes the results in an interview. Professor Kuhle, almost everyone is infected with the Epstein-Barr virus (EBV), usually without symptoms.

Physics - Pharmacology - 13.01.2022

Keeping up with the first law of robotics: A new photonic effect for accelerated drug discovery
Physicists at the University of Bath and University of Michigan demonstrate a new photonic effect in semiconducting nanohelices. A new photonic effect in semiconducting helical particles with nanoscale dimensions has been discovered by an international team of scientists led by researchers at the University of Bath.

Physics - Pharmacology - 13.01.2022

New photonic effect could speed drug development
Twisted semiconductor nanostructures convert red light into the twisted blue light in tiny volumes, which may help develop chiral drugs Twisted nanoscale semiconductors manipulate light in a new way, researchers at the University of Bath and the University of Michigan have shown. The effect could be harnessed to accelerate the discovery and development of life-saving medicines as well as photonic technologies.

Pharmacology - Health - 12.01.2022

A new biochip that reduces the cost of manufacturing in vitro skin has been developed
Researchers from the Universidad Carlos III de Madrid (UC3M), the Universidad Politécnica de Madrid (UPM) and other entities have designed a new biochip, a device that simplifies the process of manufacturing in vitro skin in the laboratory and other complex multi-layer tissues. Human skin modelled using this device could be used in medicine and cosmetic testing, which would reduce the cost of these preclinical trials.

Health - Pharmacology - 11.01.2022

Led team refines ’kick and kill’ strategy aimed at eliminating HIV-infected cells
In a study using mice, a UCLA-led team of researchers have improved upon a method they developed in 2017 that was designed to kill HIV-infected cells. The advance could move scientists a step closer to being able to reduce the amount of virus, or even eliminate it, from infected people who are dependent on lifesaving medications to keep the virus from multiplying and illness at bay.

Life Sciences - Pharmacology - 10.01.2022

Improved motor, sensory, and cognitive recovery after stroke
Stroke survivors have improved recovery of hand and arm function with the help a new rehabilitation protocol thanks to finely tuned electrostimulation of target muscles in the arm. After lying for a while in a way that puts pressure on a nerve in your arm, it may happen that you no longer feel your arm anymore.