News in Brief
Health - Mar 26
UC San Diego Engineers and Doctors Team Up to Retrofit and Build Ventilators with 3D-Printing
UC San Diego Engineers and Doctors Team Up to Retrofit and Build Ventilators with 3D-Printing
Health - Mar 26
State-level data misses growing coronavirus hot spots in U.S., including in the South
State-level data misses growing coronavirus hot spots in U.S., including in the South
Mathematics - Mar 26
Growing plants without soil amongst frontier projects backed by President’s fund
Growing plants without soil amongst frontier projects backed by President’s fund
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Health - Pharmacology - 27.03.2020
Health - Pharmacology - 27.03.2020 
An experimental peptide could block Covid-19
MIT chemists are testing a protein fragment that may inhibit coronaviruses' ability to enter human lung cells. The research described in this article has been published on a preprint server but has not yet been peer-reviewed by scientific or medical experts. In hopes of developing a possible treatment for Covid-19, a team of MIT chemists has designed a drug candidate that they believe may block coronaviruses' ability to enter human cells.
Pharmacology - Health - 26.03.2020
Pharmacology - Health - 26.03.2020
Health - Pharmacology - 25.03.2020
Pharmacology - 24.03.2020
Health - Pharmacology - 24.03.2020 
A stopgap measure to treat respiratory distress
Repurposing a drug used for blood clots may help Covid-19 patients in danger of respiratory failure, researchers suggest. Researchers at MIT and the University of Colorado at Denver have proposed a stopgap measure that they believe could help Covid-19 patients who are in acute respiratory distress. By repurposing a drug that is now used to treat blood clots, they believe they could help people in cases where a ventilator is not helping, or if a ventilator is not available.
Health - Pharmacology - 24.03.2020
Pharmacology - Administration - 24.03.2020 
Oxford’s COVID-19 research receives government funding
Three Oxford-based COVID-19 projects are among the first to benefit from a share of £20 million in government investment. The three projects include work on an effective vaccine, enabling pre-clinical and clinical vaccine trials, as well as supporting researchers to develop manufacturing processes to produce a vaccine at a million-dose scale. Another project will examine how existing treatments could be repurposed to treat coronavirus.
Life Sciences - Pharmacology - 23.03.2020
Health - Pharmacology - 23.03.2020 
Fighting coronavirus: Imperial researchers secure funds to help tackle COVID-19
Two Imperial research projects are among the first to receive national funding as part of a stream of work to help fight the coronavirus pandemic. In the first round of funding announced by the UK Medical Research Council today, work will begin at the College to develop a potential antibody therapy for COVID-19, as well as clinical project to help to answer some of the key questions about the symptoms and course of the disease.
Pharmacology - Health - 23.03.2020 
IOR lays the foundation for a new clinical trial against lymphomas
A study conducted by med. Francesco Bertoni at the Institute of Oncology Research ( IOR , affiliated to USI) has shown that a specific combination of drugs is a potentially winning strategy in the fight against lymphomas. The results obtained in the laboratory have enabled the researchers at the Istituto Oncologico della Svizzera italiana ( IOSI ) to develop a clinical study together with the Swiss Group for Clinical Cancer Research ( SAKK ).
Health - Pharmacology - 20.03.2020
Pharmacology - Life Sciences - 20.03.2020 
In pictures: the Imperial lab developing a COVID-19 vaccine
Scores of researchers are racing to create a virus to combat the coronavirus COVID-19. Professor Robin Shattock and his team in Imperial College London's Department of Infectious Disease developed a candidate vaccine within 14 days of getting the sequence from China. They have been testing the vaccine on animals since 10 February and plan to move to clinical trials in the summer.
Health - Pharmacology - 17.03.2020
Health - Pharmacology - 17.03.2020
Health - Pharmacology - 16.03.2020
Pharmacology - Health - 13.03.2020 
Ouch: Patients prescribed opioids after tooth extraction report worse pain
The use of opioids to soothe the pain of a pulled tooth could be drastically reduced or eliminated altogether from dentistry, say University of Michigan researchers. More than 325 dental patients who had teeth pulled were asked to rate their pain and satisfaction within six months of extraction. Roughly half of the study's patients who had surgical extraction and 39% who had routine extraction were prescribed opioids.
Pharmacology - 13.03.2020
Pharmacology - Health - 12.03.2020
Pharmacology
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Oxford COVID-19 vaccine programme opens for clinical trial recruitment
University of Oxford researchers working in an unprecedented vaccine development effort to prevent COVID-19 have started screening healthy volunteers (aged 18-55) today for their upcoming ChAdOx1 nCoV-19 vaccine trial in the Thames Valley Region. The vaccine based on an adenovirus vaccine vector and the SARS-CoV-2 spike protein is already in production but won't be ready for some weeks still.
University of Oxford researchers working in an unprecedented vaccine development effort to prevent COVID-19 have started screening healthy volunteers (aged 18-55) today for their upcoming ChAdOx1 nCoV-19 vaccine trial in the Thames Valley Region. The vaccine based on an adenovirus vaccine vector and the SARS-CoV-2 spike protein is already in production but won't be ready for some weeks still.
MIT chemists are testing a protein fragment that may inhibit coronaviruses' ability to enter human lung cells. The research described in this article has been published on a preprint server but has not yet been peer-reviewed by scientific or medical experts. In hopes of developing a possible treatment for Covid-19, a team of MIT chemists has designed a drug candidate that they believe may block coronaviruses' ability to enter human cells.
’More effective’ stem cell transplant method could aid blood cancer patients
Researchers at UCL have developed a new way to make blood stem cells present in the umbilical cord 'more transplantable', a finding in mice which could improve the treatment of a wide range of blood diseases in children and adults. Blood stem cells, also known as haematopoietic stem cells (HSCs), generate every type of cell in the blood (red cells, white cells and platelets), and are responsible for maintaining blood production throughout life.
Researchers at UCL have developed a new way to make blood stem cells present in the umbilical cord 'more transplantable', a finding in mice which could improve the treatment of a wide range of blood diseases in children and adults. Blood stem cells, also known as haematopoietic stem cells (HSCs), generate every type of cell in the blood (red cells, white cells and platelets), and are responsible for maintaining blood production throughout life.
Medications against coronavirus in trial
Clinical trials on Covid-19 at university hospital TUM Klinikum rechts der Isar The university hospital is participating in studies on new medications for people suffering from Covid-19. As part of a clinical study, patients can be treated with medications that are still under development. 50 patients infected with the novel Coronavirus are currently being treated at the university hospital TUM Klinikum rechts der Isar.
Clinical trials on Covid-19 at university hospital TUM Klinikum rechts der Isar The university hospital is participating in studies on new medications for people suffering from Covid-19. As part of a clinical study, patients can be treated with medications that are still under development. 50 patients infected with the novel Coronavirus are currently being treated at the university hospital TUM Klinikum rechts der Isar.
New Hepatitis C cases down by almost 70 per cent in HIV positive men
New cases of hepatitis C amongst HIV positive men in London and Brighton have fallen by nearly 70 per cent in recent years. An analysis of five clinics in London and Brighton found that 378 cases were diagnosed between July 2013 - June 2018. New infections peaked at 14 per 1000 people studied in 2015, falling to 4 per 1000 by 2018.
New cases of hepatitis C amongst HIV positive men in London and Brighton have fallen by nearly 70 per cent in recent years. An analysis of five clinics in London and Brighton found that 378 cases were diagnosed between July 2013 - June 2018. New infections peaked at 14 per 1000 people studied in 2015, falling to 4 per 1000 by 2018.
May help older adults stay physically capable for longer
Drug therapies that help older adults maintain their skeletal muscle mass and physical function for longer could be a step closer after researchers at the University of Birmingham identify a key mechanism that drives the clearance of damaged mitochondria. A team in the University's School of Sport, Exercise and Rehabilitation Sciences are well-versed at investigating dynamic machinery within cells called mitochondria.
Drug therapies that help older adults maintain their skeletal muscle mass and physical function for longer could be a step closer after researchers at the University of Birmingham identify a key mechanism that drives the clearance of damaged mitochondria. A team in the University's School of Sport, Exercise and Rehabilitation Sciences are well-versed at investigating dynamic machinery within cells called mitochondria.
Repurposing a drug used for blood clots may help Covid-19 patients in danger of respiratory failure, researchers suggest. Researchers at MIT and the University of Colorado at Denver have proposed a stopgap measure that they believe could help Covid-19 patients who are in acute respiratory distress. By repurposing a drug that is now used to treat blood clots, they believe they could help people in cases where a ventilator is not helping, or if a ventilator is not available.
UC San Diego Health Launches Clinical Trial to Assess Antiviral Drug for COVID-19
With three other UC Health medical centers, NIH-sponsored trial will study whether remdesivir, an investigational antiviral drug, may be a safe and effective agent against the novel coronavirus that causes COVID-19 Physician-scientists at four University of California Health medical centers — UC San Diego Health, UC San Francisco, UC Irvine Health and UC Davis Health — have begun recruiting participants for a Phase II clinical trial
With three other UC Health medical centers, NIH-sponsored trial will study whether remdesivir, an investigational antiviral drug, may be a safe and effective agent against the novel coronavirus that causes COVID-19 Physician-scientists at four University of California Health medical centers — UC San Diego Health, UC San Francisco, UC Irvine Health and UC Davis Health — have begun recruiting participants for a Phase II clinical trial
Three Oxford-based COVID-19 projects are among the first to benefit from a share of £20 million in government investment. The three projects include work on an effective vaccine, enabling pre-clinical and clinical vaccine trials, as well as supporting researchers to develop manufacturing processes to produce a vaccine at a million-dose scale. Another project will examine how existing treatments could be repurposed to treat coronavirus.
UChicago chemists race to decode RNA of new coronavirus
As scientists around the world race to decode the coronavirus that has caused more than 15,000 deaths in a matter of months, a group of University of Chicago chemists are focusing on understanding how the virus's RNA works-which could translate to a more effective vaccine. COVID-19, like many other viruses, is made solely out of RNA, the set of molecules that most of us remember learning in biology class as messengers that carry out instructions from DNA.
As scientists around the world race to decode the coronavirus that has caused more than 15,000 deaths in a matter of months, a group of University of Chicago chemists are focusing on understanding how the virus's RNA works-which could translate to a more effective vaccine. COVID-19, like many other viruses, is made solely out of RNA, the set of molecules that most of us remember learning in biology class as messengers that carry out instructions from DNA.
Two Imperial research projects are among the first to receive national funding as part of a stream of work to help fight the coronavirus pandemic. In the first round of funding announced by the UK Medical Research Council today, work will begin at the College to develop a potential antibody therapy for COVID-19, as well as clinical project to help to answer some of the key questions about the symptoms and course of the disease.
A study conducted by med. Francesco Bertoni at the Institute of Oncology Research ( IOR , affiliated to USI) has shown that a specific combination of drugs is a potentially winning strategy in the fight against lymphomas. The results obtained in the laboratory have enabled the researchers at the Istituto Oncologico della Svizzera italiana ( IOSI ) to develop a clinical study together with the Swiss Group for Clinical Cancer Research ( SAKK ).
Kids exposed to TB at higher risk of disease than thought
Stanford scientists led the first comprehensive effort since the 1940s to measure how likely children are to develop tuberculosis when a family member has the disease. Young children exposed to tuberculosis are at surprisingly high risk of developing the disease, according to research led by the School of Medicine.
Stanford scientists led the first comprehensive effort since the 1940s to measure how likely children are to develop tuberculosis when a family member has the disease. Young children exposed to tuberculosis are at surprisingly high risk of developing the disease, according to research led by the School of Medicine.
Scores of researchers are racing to create a virus to combat the coronavirus COVID-19. Professor Robin Shattock and his team in Imperial College London's Department of Infectious Disease developed a candidate vaccine within 14 days of getting the sequence from China. They have been testing the vaccine on animals since 10 February and plan to move to clinical trials in the summer.
Hydrogel could be step forward in therapies to generate bones in head and neck
A team of UCLA School of Dentistry researchers has developed the first adhesive hydrogel specifically to regenerate bone and tissue defects following head and neck surgeries. Their invention was inspired in part by the way that marine mussels can stick to wet surfaces. Their research is published online Translational Medicine.
A team of UCLA School of Dentistry researchers has developed the first adhesive hydrogel specifically to regenerate bone and tissue defects following head and neck surgeries. Their invention was inspired in part by the way that marine mussels can stick to wet surfaces. Their research is published online Translational Medicine.
COVID-19: Imperial researchers model likely impact of public health measures
Researchers from Imperial have analysed the likely impact of multiple public health measures on slowing and suppressing the spread of coronavirus. The latest analysis comes from a team modelling the spread and impact COVID-19 and whose data are informing current UK government policy on the pandemic.
Researchers from Imperial have analysed the likely impact of multiple public health measures on slowing and suppressing the spread of coronavirus. The latest analysis comes from a team modelling the spread and impact COVID-19 and whose data are informing current UK government policy on the pandemic.
Faecal Microbiota Transplants successfully treat patients with C.diff
A new study from the University of Birmingham has shown that Faecal Microbiota Transplants (FMT) are highly successful in treating patients with Clostridioides difficile (C.diff) infection. Published in EClinical Medicine , results from the first licenced English stool bank, which supplies FMT treatment to patients in the NHS, have shown that in 78% of cases the patient's diarrhoea had stopped and had not returned in the 90 days after treatment.
A new study from the University of Birmingham has shown that Faecal Microbiota Transplants (FMT) are highly successful in treating patients with Clostridioides difficile (C.diff) infection. Published in EClinical Medicine , results from the first licenced English stool bank, which supplies FMT treatment to patients in the NHS, have shown that in 78% of cases the patient's diarrhoea had stopped and had not returned in the 90 days after treatment.
The use of opioids to soothe the pain of a pulled tooth could be drastically reduced or eliminated altogether from dentistry, say University of Michigan researchers. More than 325 dental patients who had teeth pulled were asked to rate their pain and satisfaction within six months of extraction. Roughly half of the study's patients who had surgical extraction and 39% who had routine extraction were prescribed opioids.
Trump’s tweets influence anti-vaxxers
Trump supporters are more likely to believe conspiracy theories and hold anti-vaccination views, a University of Queensland study on American internet users has found. UQ researcher Professor Matthew Hornsey said Mr Trump had sent dozens of tweets linking vaccinations with autism before he became President, despite this link being a long-discredited myth.
Trump supporters are more likely to believe conspiracy theories and hold anti-vaccination views, a University of Queensland study on American internet users has found. UQ researcher Professor Matthew Hornsey said Mr Trump had sent dozens of tweets linking vaccinations with autism before he became President, despite this link being a long-discredited myth.
Potential treatment for Lyme disease kills bacteria that may cause lingering symptoms
See us on twitter See us on youtube See us on linkedin See us on instagram Screening thousands of drugs, Stanford scientists determined that in mice, azlocillin, an antibiotic approved by the Food and Drug Administration, eliminated the bacteria that causes Lyme disease. For decades, the routine treatment for Lyme disease has been standard antibiotics, which usually kill off the infection.
See us on twitter See us on youtube See us on linkedin See us on instagram Screening thousands of drugs, Stanford scientists determined that in mice, azlocillin, an antibiotic approved by the Food and Drug Administration, eliminated the bacteria that causes Lyme disease. For decades, the routine treatment for Lyme disease has been standard antibiotics, which usually kill off the infection.
News in Brief
Health - Mar 26
UC San Diego Engineers and Doctors Team Up to Retrofit and Build Ventilators with 3D-Printing
UC San Diego Engineers and Doctors Team Up to Retrofit and Build Ventilators with 3D-Printing
Health - Mar 26
State-level data misses growing coronavirus hot spots in U.S., including in the South
State-level data misses growing coronavirus hot spots in U.S., including in the South
Mathematics - Mar 26
Growing plants without soil amongst frontier projects backed by President’s fund
Growing plants without soil amongst frontier projects backed by President’s fund