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Health - Life Sciences - 19.07.2024 - Today
Turning off inflammatory protein extends healthy lifespan in mice
Turning off inflammatory protein extends healthy lifespan in mice
Scientists have discovered that 'turning off' a protein called IL-11 can significantly increase the healthy lifespan of mice by almost 25%. Researchers in the UK and Singapore have found that targeting the production of a key inflammatory protein in mice can extend their lifespan, reduce age-related disease and make older animals less frail.

Health - Life Sciences - 19.07.2024 - Today
Enhancing breast cancer diagnosis and treatment
Enhancing breast cancer diagnosis and treatment
Addressing problems with diagnosing and treating breast cancer, scientists at EPFL have developed EMBER, a tool that integrates breast cancer transcriptomic data from multiple databases. EMBER can improve precision oncology by accurately predicting molecular subtypes and therapy responses. Breast cancer is the most frequently diagnosed cancer worldwide.

Life Sciences - Health - 18.07.2024
Analysing internal world models of humans, animals and AI
Analysing internal world models of humans, animals and AI
Freiburg researchers develop new formal description of internal world models, thereby enabling interdisciplinary research A team of scientists led by Ilka Diester , Professor of Optophysiology and spokesperson of the BrainLinks-BrainTools research centre at the University of Freiburg, has developed a formal description of internal world models and published it in the journal Neuron .

Health - Pharmacology - 18.07.2024
Improving HIV treatment for children and adolescents - the right way
Improving HIV treatment for children and adolescents - the right way
Globally, around 2.6 million children and adolescents are currently living with HIV, the majority of them in Africa. These young people are much more likely to experience treatment failure than adults. Experts long assumed that testing for viral drug resistance could improve treatment in cases where treatment has failed.

Physics - Health - 18.07.2024
New imaging technique could diagnose cancer metastasis
New technique to diagnose cancer metastasis uses origami nanoprobes A team of Johns Hopkins engineers can locate aggressive cancers using laser light and folded DNA Johns Hopkins engineers have created a new optical tool that could improve cancer imaging. Their approach, called SPECTRA, uses tiny nanoprobes that light up when they attach to aggressive cancer cells, helping clinicians distinguish between localized cancers and those that are metastatic and have the potential to spread throughout the body.

Health - Life Sciences - 18.07.2024
A less burdensome approach to sickle cell treatment
Gene-editing approach could offer new hope to sickle cell patients Johns Hopkins team's innovative nanoparticle approach aims to reduce side effects and treatment burden Current gene therapies to treat sickle cell disease are complex, time-consuming, and are sometimes linked to serious side effects like infertility or blood cancer.

Chemistry - Health - 17.07.2024
Soft, stretchy 'jelly batteries' inspired by electric eels
Soft, stretchy ’jelly batteries’ inspired by electric eels
Researchers have developed soft, stretchable 'jelly batteries' that could be used for wearable devices or soft robotics, or even implanted in the brain to deliver drugs or treat conditions such as epilepsy. The researchers, from the University of Cambridge, took their inspiration from electric eels, which stun their prey with modified muscle cells called electrocytes.

Health - Life Sciences - 17.07.2024
Scientists make breakthrough in development of fridge-free storage for vital medicines
Scientists make breakthrough in development of fridge-free storage for vital medicines
Scientists have developed a new approach to store and distribute crucial protein therapeutics without the need for fridges or freezers. The breakthrough, published in the journal Nature , could significantly improve accessibility of essential protein-based drugs in developing countries where cold storage infrastructure may be lacking, helping efforts to diagnose and treat more people with serious health conditions.

Life Sciences - Health - 17.07.2024
Addition to the CRISPR Toolbox: Teaching Gene Scissors to Detect RNA
Addition to the CRISPR Toolbox: Teaching Gene Scissors to Detect RNA
A team at the Helmholtz Centre for Infection Research in Würzburg, Germany, led by RNA expert Chase Beisel, has developed a new technology for the precise detection of RNA using DNA-cutting Cas12 nucleases. CRISPR-Cas systems, defense systems in bacteria, have become a plentiful source of technologies for molecular diagnostics.

Health - Psychology - 17.07.2024
’Diabetes distress’ increases risk of mental health problems among young people living with type 1 diabetes
Children diagnosed with type 1 diabetes are at significantly higher risk of a number of mental health issues, including mood and anxiety disorders, a study from a team in the UK and the Czech Republic has found. We know that people diagnosed with type 1 diabetes can experience 'diabetes distress'. It's little wonder, then, that they are at risk of compounding mental health problems, spanning into their adult lives Benjamin Perry The findings highlight the urgent need for monitoring and support for the mental health of young people diagnosed with type 1 diabetes.

Pharmacology - Health - 17.07.2024
Scottish Brain Tumour Research Centre of Excellence to be established
University of Glasgow cancer scientists will play a leading role in a new research centre to help find a cure for the most aggressive form of brain cancer. The Scottish Brain Tumour Research Centre of Excellence is jointly funded by the charities Brain Tumour Research and Beatson Cancer Charity, and will be a unique collaboration based at laboratories at the University of Glasgow and the University of Edinburgh.

Health - Life Sciences - 17.07.2024
Multiple concussions in rugby players change proteins in their blood
A new study shows that retired rugby players who have suffered multiple concussions have abnormal levels of certain proteins in their blood. This may make them more prone to developing diseases such as motor neurone disease (MND). This is what new research led by our bioscientists has found as part of the UK Rugby Health project.

Life Sciences - Health - 17.07.2024
'Paleolithic' diets are not without risks
’Paleolithic’ diets are not without risks
A study highlights the toxicity risks of high-protein diets, which can lead to severe neurological disorders. High-protein diets, known as ''Paleolithic diets'', are popular. Using mouse models, scientists at the University of Geneva have studied their impact. While effective in regulating weight and stabilizing diabetes, these diets are not without risks.

Health - Innovation - 17.07.2024
A hydrogel implant to treat endometriosis
Researchers from ETH Zurich and Empa have developed a hydrogel implant that can help prevent endometriosis, a condition that affects a great many women. This innovation also acts as a contraceptive. Hydrogels have a variety of use cases, including contact lenses, delivering doses of medication within the body, moisturisers, water storage in soil, cleaning polluted water and as gelling and thickening agents.

Health - Pharmacology - 17.07.2024
Key Driver for Epithelial Cancer Development Identified
Key Driver for Epithelial Cancer Development Identified
A distinct signaling pathway called TNF- drives the transformation of epithelial cells into aggressive tumor cells. During cancer progression, cells activate their own TNF- program and become invasive. This finding could help to improve early detection and treatment of patients with cancers in skin, esophagus, bladder or colon, as researchers state.

Health - Life Sciences - 17.07.2024
Scientists make breakthrough in fridge-free storage for vital medicines
Scientists have developed a new approach to store and distribute crucial protein therapeutics without the need for fridges or freezers. The breakthrough, published in the journal Nature , could significantly improve accessibility of essential protein-based drugs in developing countries where cold storage infrastructure may be lacking, helping efforts to diagnose and treat more people with serious health conditions.

Health - 17.07.2024
Ultra-processed food makes up almost two-thirds of calorie intake of UK adolescents
Ultra-processed food makes up almost two-thirds of calorie intake of UK adolescents
Adolescents consume around two-thirds of their daily calories from ultra-processed foods (UPFs), new research from the Universities of Cambridge and Bristol has found. Ultra-processed foods make up the majority of adolescents' diets, and their consumption is at a much higher level than is ideal, given their potential negative health impacts Yanaina Chavez-Ugalde The study found that UPF consumption was highest among adolescents from deprived backgrounds, those of white ethnicity, and younger adolescents.

Life Sciences - Health - 17.07.2024
Study addresses long-standing diversity bias in human genetics
Study addresses long-standing diversity bias in human genetics
New study addresses long-standing diversity bias in human genetics Catalog of data generated by Johns Hopkins scientists includes groups traditionally neglected in research, should yield more accurate insights into genetic factors driving human diversity Most research in human genetics has historically focused on people of European ancestries-a long-standing bias that may limit the accuracy of scientific predictions for people from other populations.

Health - 16.07.2024
Antibiotics in early life increase risk of asthma and allergies in adulthood
Taking antibiotics at a young age can make the body more prone to asthma and allergies later in life. This might be preventable by adding a simple supplement, concludes immunologist Olaf Perdijk from Utrecht University. His comprehensive study is published today in the journal Immunity . Antibiotics are essential for eliminating harmful bacteria and have significantly advanced our healthcare.

Life Sciences - Health - 16.07.2024
First bone marrow model which supports human stem cells
Scientists develop first bone marrow model which supports human stem cells Scientists have created the first bioengineered bone marrow model which can support the type of human stem cells that are crucial for bone marrow transplants and in vitro study work. The research - published in Nature Communications and led by the University of Glasgow - replicates key aspects of the human bone marrow microenvironment, to enable the support of rare long-term hematopoietic stem cells, or LT-HSCs.
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