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Monoclonal antibodies - treatments developed by cloning a cell that makes an antibody - could help provide an answer to the growing problem of antimicrobial resistance, say scientists.

Science + Technology A cumulative adversity index created by researchers could be adapted to help conservation efforts Key takeaways The cumulative adversity index for people quantifies numerous measures of hardship, such as poverty and stress to understand health and longevity over the individual's lifespan.

Exposure to arsenic and other toxic metals may accelerate the progression toward diabetes, according to a new study by University of Illinois Chicago researchers. In a longitudinal study of over 500 Mexican Americans living in southern Texas, researchers found that high levels of toxic metals in urine predicted faster increases in blood sugar over subsequent years.

People who eat more ultra-processed foods (UPF) are at increased risk of developing type 2 diabetes, but this risk can be lowered by consuming less processed foods instead, finds a new study led by researchers at UCL. The study, published in The Lancet Regional Health - Europe in collaboration with experts at the University of Cambridge and Imperial College London, investigated the relationship between the degree of food processing and type 2 diabetes risk, including which kinds of UPF were most high-risk.

The birds save more energy prior their migration to the south than they consume during the flight itself Millions of birds migrate every year to escape winter, but spending time in a warmer climate does not save them energy, according to research by the Max Planck Institute of Animal Behavior in Konstanz, Germany.

There is a significant improvement in the cognition of children who have undergone brain surgery for epilepsy, finds a new study by UCL researchers. The study, published in Brain , retrospectively analysed the records of 500 children who had undergone epilepsy surgery at Great Ormond Street Hospital (GOSH) between the years of 1990 and 2018.

A team of international researchers at the University of Oxford (Oxford) and Nanyang Technological University, Singapore (NTU Singapore), has discovered a new process for repairing damaged DNA that is particularly relevant for patients undergoing colorectal cancer treatments. Reporting their finding in Cell , the researchers describe a new process in DNA repair in which cells remove harmful DNA-protein lesions from a cell's nucleus, ensuring the stability of their genetic material and promoting cell survival.

A study carried out at the University of Bonn identifies a control circuit in flies essential for the consumption of food Researchers at the University of Bonn and the University of Cambridge have identified an important control circuit involved in the eating process. The study has revealed that fly larvae have special sensors, or receptors, in their esophagus that are triggered as soon as the animal swallows something.

Scientists have found a way to create artificial sugars that could lead to better ways to diagnose and treat diseases more accurately than ever before. Sugars play a crucial role in human health and disease, far beyond being just an energy source. Complex sugars called glycans coat all'our cells and are essential for healthy function.

University of Sydney research has found people over 65 are being prescribed antidepressants as pain treatment based on international guidelines that use limited evidence. The study found that in the last 40 years there have been only 15 trials globally focusing on the benefit of antidepressants for pain in older people.

Mutations in the BRCA1 gene increase the risk of breast and ovarian cancer in females and prostate cancer in males. Despite more than 15,000 papers studying BRCA1 mutations and numerous clinical reports, the exact role of the BRCA1 protein has been poorly understood. A recent paper, published in the prestigious scientific journal Nature, provides novel insights into the BRCA1 function during the repair of broken DNA.

Cardiff researchers are examining how the use of WhatsApp can engage black men in Butetown and Grangetown with prostate cancer risk information and increase prostate cancer awareness. New research funded by Cancer Research UK will fund a collaborative project at Cardiff University to examine the effectiveness of using WhatsApp as a tool for sharing cancer risk information among peers in the black community.

A new study aims, for the first time, to pinpoint the very moment the immune system recognizes a tumour to try to stop the disease earlier than previously possible. This research has the potential to give an entirely new perspective on the role of the immune system in cancer progression Heather Machado Currently cancer is usually diagnosed when tumours are already developed requiring, often significant, treatment to remove them and prevent further growth.

Discovery highlights importance of including both male and female subjects in neuroscience research and considering sex in determining treatment approaches A new study has uncovered significant differences in how male and female mice process threats, even as they exhibit similar behavioural responses.

University of Queensland research has found use of the opioid oxycodone in Australia almost halved after changes to packaging and prescribing practices in 2019. Dr Rory Verhagen from UQ's Queensland Alliance for Environmental Health Sciences analysed data from 6,999 samples from more than 50 wastewater treatment plants across Australia between April 2017 to April 2023 as part of the National Wastewater Drug Monitoring program.

Study: The manganese transporter SLC39A8 links alkaline ceramidase 1 to inflammatory bowel disease (DOI: 10.1038/s41467'024 -49049-8) Researchers at the University of Michigan have delved deeper into the relationship between manganese deficiency and inflammatory bowel disease and found that low levels of the micronutrient can exacerbate intestinal injury and inflammation.

Bonn researchers clarify the function of specialized nerve cells in memory formation Specialized nerve cells in the temporal lobe react highly selectively to images and names of a single person or specific objects. Researchers at the University Hospital Bonn (UKB) and the University of Bonn have provided direct evidence for the first time that the so-called concept neurons are indeed the building blocks of our memory for experiences.

UCL is releasing its animal research statistics today in collaboration with Understanding Animal Research - a non-profit that promotes open communications about animal research. UCL and nine other institutions together conducted over half of all'animal procedures - those used in medical, veterinary, and scientific research - in the UK in 2023.

Surgical removal of the prostate to treat prostate cancer is currently determined on the basis of tissue sample analysis (Gleason grading). As this method is invasive and often unreliable, scientists around the world are looking for alternatives. A research team at MedUni Vienna has now developed a new method that can be used to identify those patients for whom surgical treatment is the best option.

L'alimentation serait responsable d'environ 30% des décès dus aux maladies cardiovasculaires. Cardiovascular diseases are the leading cause of mortality in Western Europe, accounting for 1/3 of deaths in 2019. Diet is thought to be responsible for around 30% of such deaths. Nutrition-related prevention policies therefore constitute a major public health challenge for these diseases.