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New research finds that PCT (procalcitonin) blood test does not lower antibiotic treatment duration for hospitalised children . A study led by the University of Liverpool, in collaboration with Cardiff University's Centre of Clinical Trials Research, has found that despite previous promising analysis, a blood test used to diagnose infection and sepsis did not reduce the time children spend on intravenous antibiotics in hospitals.

A team from UNIGE-HUG Centre for Emerging Viral Diseases, MSF, MSF Epicentre, Johns Hopkins University and South Sudanese Ministry of Health has demonstrated the effectiveness of a vaccine against hepatitis E, during an epidemic, in South Sudan.

A recent study led by MedUni Vienna provides new insights into the mechanisms of coagulation in persons with haemophilia A, the most common form of haemophilia. The research team was able to show that saliva contains special vesicles that trigger rapid coagulation of the blood of haemophilic patients.

A new look at cancer cells: Würzburg researchers show in the journal 'Science' how therapeutic antibodies work - thanks to an innovative method of super-resolution microscopy. In blood cancers such as chronic lymphocytic leukaemia, B cells of the immune system multiply uncontrollably. One form of therapy involves labelling the CD20 protein on the surface of the B cells with customised antibodies.

Researchers from the Vienna Lung Transplant Program of MedUni Vienna and University Hospital Vienna have published the first prospective, randomized and controlled study on the use of extracorporeal photopheresis (ECP) in lung transplantation in the renowned European Respiratory Journal. The findings could significantly change the standard procedure for rejection reactions after lung transplants.

New research from the Royal Veterinary College (RVC), in collaboration with the West Bengal University of Animal & Fishery Sciences (WBUAFS), explored antibiotic use in chicken farming in eastern India, revealing how poultry companies play a significant role in influencing the way antibiotics are used during food production compared to chicken farmers.

Artificial Intelligence (AI) could help doctors identify follicles that are most likely to lead to the birth of a baby during IVF treatment. During IVF treatment, doctors use ultrasound scans to monitor the size of follicles - small sacs in the ovaries containing eggs - to decide when to give a hormone injection known as the 'trigger' to prepare the eggs for collection and ensure that they are ready to be fertilised with sperm to create embryos.

Diabetic neuropathy, a common complication of diabetes, manifests itself in the loss of sensation in the feet leading to chronic pain and ulcers, in severe cases even to amputations. While previous interventions have aimed to alleviate the symptoms, the non-invasive neuroprosthesis developed by an international research team led by Stanisa Raspopovic from MedUni Vienna addresses the cause.

New study is a landmark step towards better personalised medicine for cancer patients. An international team of UK and US scientists has discovered that the activity of macrophages - a type of white blood cell that engulf pathogens and cancer cells - can be used to predict whether or not a melanoma patient will respond to immunotherapy.

Creutzfeldt-Jakob disease (CJD) is a very rare neurodegenerative disease that is fatal within a few months and still poses many questions to scientists. To date, no specific symptoms are known that precede the onset of the disease. A suspected diagnosis can usually be made on the basis of a particular combination of symptoms and examination findings, but can only be confirmed after the death of the affected person.

Findings could impact the interpretation of previous clinical trial results, including the EMBARK trial, which relied on standard imaging A new study led by researchers at the UCLA Health Jonsson Comprehensive Cancer Center has found that many cases of high-risk nonmetastatic hormone-sensitive prostate cancer may be more advanced than previously thought.

Tuberculosis (TB) is the world's biggest infectious disease killer with multidrug-resistant TB (MDR-TB) posing a particular threat to global health. A study led by the Swiss Tropical and Public Health Institute (Swiss TPH) shows that resistance to the new MDR-TB treatment regimen recently recommended by the World Health Organization is already spreading between patients.

Using this model, researchers may be able to identify antibody drugs that can target a variety of infectious diseases. By adapting artificial intelligence models known as large language models, researchers have made great progress in their ability to predict a protein's structure from its sequence. However, this approach hasn't been as successful for antibodies, in part because of the hypervariability seen in this type of protein.

VUB Research Team Presents Innovative Local Treatment for Osteolytic Bone Disease in Multiple Myeloma A team of researchers from the Translational Oncology Research Centre (TORC) of Vrije Universiteit Brussel (VUB), in collaboration with leading German universities, has developed a new biomaterial with high potential in in the treatment of bone lesions or minimal residual disease in multiple myeloma patients.

Antibody that Neutralizes Inhibitory Factors Involved in Nerve Regeneration Leads to Enhanced Motor Function Antibodies can improve the rehabilitation of people with acute spinal cord injury. Researchers at 13 clinics in Germany, Switzerland, the Czech Republic and Spain have investigated this with promising results.

A MedUni Vienna study has identified a new approach to the drug treatment of metabolic liver diseases. In an experimental study, pharmacological inhibition of an enzyme that plays a central role in fat metabolism promoted liver health reduced liver fat, inflammation and fibrotic remodeling (connective tissue scarring).

Scientists at EPFL have developed "lymphomoids," a pioneering cancer model that preserves the structure and multicellular composition of lymphoma tumors in the lab. Lymphomoids offer an innovative way to test the efficacy of lymphoma treatments and better predict individual responses. Cancer is notoriously complex, with each tumor responding to different therapies.

Scientists have identified strains of one of the world's most dangerous fungal pathogens, already resistant to our most effective antifungal drugs, which are also 5-times more likely to acquire resistance to desperately needed new treatments in development. The study - led by two University of Manchester researchers and published in Nature Communications - significantly advances our understanding of how Aspergillus fumigatus rapidly develops drug resistance.

Preclinical study suggests the compound could restore lost muscle for patients with the rare degenerative disorder A novel drug holds promise for treating Duchenne muscular dystrophy (DMD), a rare genetic disorder that causes severe muscle degeneration. McGill researchers have discovered that an experimental compound called K884 can boost the natural repair abilities of muscle stem cells.

As much as targeted therapy using so-called EGFR inhibitors has proven its worth for various types of tumours, possible side effects can be very stressful for patients. Scarring alopecia - permanent hair loss that can only be delayed but not reversed - is particularly cause for concern. Researchers at MedUni Vienna have now identified JAK inhibitors as active substances that can reactivate hair growth.