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Life Sciences - Pharmacology - 10.05.2017
A possible way to new antibiotics
A possible way to new antibiotics
Two research teams from the University of Bern and the ETH Zurich have developed a new method to shed light onto a mostly unknown process of bacterial protein production. Their results could be used for the design of new antibiotics. Ribosomes are the factories of the cell and, as such, are responsible for the fabrication of proteins.

Health - Pharmacology - 12.04.2017
Targeting blood vessels to improve cancer immunotherapy
Targeting blood vessels to improve cancer immunotherapy
EPFL scientists have improved the efficacy of cancer immunotherapy by blocking two proteins that regulate the growth of tumor blood vessels. Cancer immunotherapy aims to enhance or restore the ability of the patient's immune system - namely T'cells - to recognize and attack cancer. But tumors use several strategies to fight back immune attacks, making immunotherapy efficacious only in a minority of the patients.

Health - Pharmacology - 12.04.2017
On-the-range detection technology could corral bovine TB
On-the-range detection technology could corral bovine TB
The idea for the bovine application evolved from discussions between Lab researchers and scientists at the New Mexico health laboratory. "We have validated the assay in cows that were positive controls of a vaccination study done at the US Department of Agriculture, tested at different time points during the course of infection.

Health - Pharmacology - 04.04.2017
Using drugs to weaken traumatic memories
Physical violence, war or a natural disaster can trigger posttraumatic stress disorder (PTSD). Those affected keep reliving the traumatic event - through memories that hit them out of the blue or as recurring nightmares. As this psychological wound can't always be treated successfully with psychotherapy, scientists have long been looking for a way to influence trauma memory using drugs.

Pharmacology - Life Sciences - 30.03.2017
Anti-cancer drug gets a boost when combined with antirheumatic
Anti-cancer drug gets a boost when combined with antirheumatic
Scientists at EPFL and NTU have discovered that combining an anticancer drug with an antirheumatic produces improved effects against tumors. The discovery opens a new path for drug-drug synergy. One of the goals in pharmacology is to increase the efficiency of drugs by minimizing their side effects.

Health - Pharmacology - 28.03.2017
Birmingham experts showcase research expertise for Qatari business
Research led by University of Birmingham scientists has found that people suffering from the adrenal disorder known as Addison's disease suffer from an immune system defect which makes them prone to potentially deadly respiratory infections. The study, published online in the European Journal of Endocrinology, shows for the first time that patients with primary adrenal insufficiency (PAI) have natural killer immune cells (NK) - providing frontline protection against invading pathogens - which are not functioning properly.

Health - Pharmacology - 14.03.2017
New class of androgens play key role in polycystic ovary syndrome
The social stigma associated with diabetes and a fear of being poisoned by medical drugs may contribute to patients of South Asian origin failing to take their medication, a new study shows. South Asians in the UK are six times more likely than the general population to be affected with diabetes at a younger age and at greater risk of developing cardiovascular complications.

Health - Pharmacology - 01.03.2017
From heroin addiction to alcohol-related problems
From heroin addiction to alcohol-related problems
Around 3,000 heroin addicts currently receive opioids such as methadone, buprenorphine or morphine as part of their treatment in the Canton of Zurich.

Life Sciences - Pharmacology - 21.02.2017
New computer model shows how proteins are controlled
New computer model shows how proteins are controlled "at a distance"
EPFL scientists have created a new computer model that can help better design of allosteric drugs, which control proteins 'at a distance'. Enzymes are large proteins that are involved in virtually every biological process, facilitating a multitude of biochemical reactions in our cells. Because of this, one of the biggest efforts in drug design today aims to control enzymes without interfering with their so-called active sites - the part of the enzyme where the biochemical reaction takes place.

Pharmacology - Health - 20.02.2017
Prospect for more effective treatment of nerve pain
Prospect for more effective treatment of nerve pain
The sharp pain shoots to the face or teeth and seriously torments patients. Known as trigeminal neuralgia, it is one of the worst chronic nerve pains. The bouts are triggered by touch, such as shaving, putting on make-up, showering, talking and tooth brushing, or even a gust of wind. The cause is usually an irritation of the trigeminal nerve, the cranial nerve responsible for the sensory innervation of the facial area, parts of the scalp, and the oral cavity.

Health - Pharmacology - 17.01.2017
On track to heal leukaemia
On track to heal leukaemia
Media releases, information for representatives of the media Media Relations (E) The first clinical studies for a new type of immunotherapy for leukaemia are beginning at Bern's University Hospital and the Department of Clinical Research (DCR) of the University of Bern. Antibodies discovered in the laboratory should inhibit the growth of tumour cells.

Life Sciences - Pharmacology - 12.01.2017
Putting chromosomes through the shredder
Putting chromosomes through the shredder
When a certain human enzyme is left uncontrolled, it breaks up chromosomes into tiny pieces. This is damaging to cells, but useful for killing tumours. ETH researchers have now come to understand the underlying mechanism. Our cells contain the enzyme MUS81; this is called on in emergencies, for example, when cells are unable to replicate because the DNA-replication machinery gets tangled up in strands of DNA.

Health - Pharmacology - 07.12.2016
"Pulling" bacteria out of blood
Magnets instead of antibiotics could provide a possible new treatment method for blood infection. This involves the blood of patients being mixed with magnetic iron particles, which bind the bacteria to them after which they are removed from the blood using magnets.

Health - Pharmacology - 11.10.2016
Treating the inflammation in lymphedema
Treating the inflammation in lymphedema
ETH researchers have discovered that certain cells in the immune system suppress the development of lymphedema. Anti-inflammatory therapies could therefore be the key to treating this previously incurable condition. When the tissue fluid in our arms or legs can no longer drain properly, it begins to accumulate.

Life Sciences - Pharmacology - 27.09.2016
Vigilin, the lock keeper
Vigilin, the lock keeper
ETH researchers have discovered a molecule in liver cells that controls the release of fat into the bloodstream. This 'lock keeper? is present in large quantities in overweight people and leads indirectly to vascular narrowing. Anyone attending Munich's famous Oktoberfest will know it can leave physical traces; fatty foods and plenty of alcohol cause the liver to work overtime.

Physics - Pharmacology - 08.09.2016
Affordable detectors for gamma radiation
Affordable detectors for gamma radiation
A research team at Empa and ETH Zurich has developed single crystals made of lead halide perovskites, which are able to gage radioactive radiation with high precision. Initial experiments have shown that these crystals, which can be manufactured from aqueous solutions or low-priced solvents, work just as well as conventional cadmium telluride semi-conductors, which are considerably more complicated to produce.

Health - Pharmacology - 17.08.2016
A tiny wire with a memory to diagnose cancer
A tiny wire with a memory to diagnose cancer
EPFL researchers have used a nanowire to detect prostate cancer with greater accuracy than ever before. Their device is ten times more sensitive than any other biosensor available. Researchers at EPFL's Integrated Systems Laboratory (LSI/STI) have developed a new type of sensor that can detect tiny quantities of these markers and thus improve diagnostic accuracy.

Chemistry - Pharmacology - 09.08.2016
Synthetic Biology: Engineering a Chemical Switch into a Light-driven Proton Pump
Synthetic Biology: Engineering a Chemical Switch into a Light-driven Proton Pump
Synthetic biology is an emerging and rapidly evolving engineering discipline.

Health - Pharmacology - 18.07.2016
Travelers import superbugs
Travelers import superbugs
Many tourists returning from India were found colonized with multidrug-resistant 'superbugs'.

Chemistry - Pharmacology - 06.07.2016
Replacing oil with wood for the production of chemicals
Replacing oil with wood for the production of chemicals
Two research projects of the National Research Programme Resource Wood have developed new processes to replace petroleum with wood for the production of important chemicals.
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