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Pharmacology - Health - 15.07.2021
When insurers and doctors haggle over Medicaid costs, patients pay the price
Reimbursement negotiations can exacerbate health care disparities, new study finds When physicians and insurers haggle over reimbursement payments, health care providers lose revenue due to extra administrative burdens-an issue that is particularly acute with Medicaid, a key part of the social safety net that serves many low-income families.

Economics / Business - Pharmacology - 15.07.2021
When insurance companies haggle over Medicaid costs, patients pay the price
Reimbursement negotiations can exacerbate health care disparities, new study finds When physicians and insurers haggle over reimbursement payments, health care providers lose revenue due to extra administrative burdens-an issue that is particularly acute with Medicaid, a key part of the social safety net that serves many low-income families.

Health - Pharmacology - 15.07.2021
Common Medication Used to Reduce Cholesterol Levels May Reduce COVID-19 Severity 
Using anonymized medical records from a national registry, UC San Diego researchers confirm earlier findings that statins may substantially minimize adverse outcomes from SARS-CoV-2 infection  In a new study from University of California San Diego School of Medicine, researchers have confirmed that patients taking statin medications had a 41 percent lower risk of in-hospital death from COVID-19.

Health - Pharmacology - 15.07.2021
Computerised image analysis identifies new subtype of debilitating lung disease
Scientists at UCL have used computer-based imaging analysis to identify new patterns of lung damage in patients with Idiopathic pulmonary fibrosis (IPF), providing the first evidence of a previously unknown and life-limiting lung disease subtype. IPF is a condition where scar tissue or fibrosis builds up in the lungs, making them thick and hard.

Health - Pharmacology - 15.07.2021
Why do scientific discoveries take long to reach the general public?
Why do scientific discoveries take long to reach the general public?
SUMMER SERIES: HOW SCIENCE WORKS For scientists, the path from bright idea to finished product is a long one. Prototypes must go through an extensive testing and approval process before they are ready for the market. Let's have a look. The results of scientific research can often bring considerable societal and economic benefits.

Health - Pharmacology - 14.07.2021
Personalised 3D printed knee implant could bring relief to thousands of arthritis sufferers
Personalised 3D printed knee implant could bring relief to thousands of arthritis sufferers
Pioneering 'printed metal' procedure to create bespoke treatment for early knee osteoarthritis set to be trialled in the UK following MHRA approval. Last updated on Thursday 15 July 2021 A groundbreaking new treatment that uses 3D printed implants and that could bring relief to tens of thousands of knee osteoarthritis sufferers has received approval to be trialled in UK patients, following a virtual "in-silico" trial that demonstrated its safety.

Health - Pharmacology - 12.07.2021
Selective, Toxin-Bearing Antibodies Could Help Treat Liver Fibrosis
In mouse models of human disease, immunotoxins targeting the protein mesothelin prevent liver cells from producing collagen, a precursor to fibrosis and cirrhosis Chronic alcohol abuse and hepatitis can injure the liver and lead to fibrosis, the buildup of collagen and scar tissue. As a potential approach to treating liver fibrosis, University of California San Diego School of Medicine researchers and their collaborators are looking for ways to stop liver cells from producing collagen.

Health - Pharmacology - 12.07.2021
Artificial Intelligence Could Be New Blueprint for Precision Drug Discovery
Mathematical approach could transform drug development by searching for disease targets, then predicting if a drug will be successful Writing in the July 12, 2021 online , researchers at University of California San Diego School of Medicine describe a new approach that uses machine learning to hunt for disease targets and then predicts whether a drug is likely to receive FDA approval.

Health - Pharmacology - 09.07.2021
Commonalities found between COVID-19 and Rheumatoid Arthritis could help development of new treatment strategies for Long Covid
Severe COVID-19 and Rheumatoid Arthritis (RA) share some common pathogenic mechanisms, according to a new study. The observations from the study - published in JCI Insight and led by the University of Glasgow's Research into Inflammatory Arthritis Centre (RACE) in collaboration with the Fondazione A.Gemelli IRCCS in Italy - could help development of new treatment strategies for severe COVID-19 and post-COVID-19 syndrome, or Long Covid.

Health - Pharmacology - 09.07.2021
Tool helps predicts who will respond best to targeted prostate cancer therapy
A new prognostic tool developed by researchers from the UCLA Jonsson Comprehensive Cancer Center and five other institutions helps p redict which men with advanced metastatic prostate cancer will respond favorably to a novel targeted therapy. The tool, described in a study published today in Lancet Oncology, analyzes a wide spectrum of imaging and clinical data and is intended to assist physicians considering treating patients with Lutetium-177 prostate-specific membrane antigen, or LuPSMA.

Health - Pharmacology - 07.07.2021
Arthritis drugs save lives of hospitalised Covid-19 patients
Drugs used to treat arthritis, known as interleukin-6 antagonists, reduce deaths and the need for mechanical ventilation among people hospitalised with Covid-19, according to a new study involving UCL which has prompted new World Health Organization (WHO) recommendations. In the study, published in the Journal of the American Medical Association , researchers analysed 27 randomised trials involving nearly 11,000 patients.

Pharmacology - Chemistry - 07.07.2021
Harnessing AI to discover new drugs inspired by nature
Artificial intelligence (AI) is able to recognise the biological activity of natural products in a targeted manner, as researchers at ETH Zurich have demonstrated. Moreover, AI helps to find molecules that have the same effect as a natural substance but are easier to manufacture. This opens up huge possibilities for drug discovery, which also have potential to rewrite the rulebook for pharmaceutical research.

Health - Pharmacology - 06.07.2021
Covid long affects four out of ten people
Covid long affects four out of ten people
More than seven months after contracting the virus, nearly 40% of symptomatic people who test positive for SARS-CoV-2 still have symptoms, reveals a study by the UNIGE and the HUG. A study by Geneva University Hospitals (HUG) and the University of Geneva on the long-term follow-up of symptomatic individuals who tested positive for SARS-CoV-2 has revealed that 39% of patients report residual symptoms seven to nine months after contracting the virus.

Health - Pharmacology - 04.07.2021
COVID vaccines: combining AstraZeneca and Pfizer may boost immunity - new study
Late last year, I asked : is it safe to have more than one type of COVID-19 vaccine? A trial has now addressed that question, as well as what effect combining different vaccine types has on immunity. Most COVID-19 vaccines require two doses, and the usual strategy is to give people the same vaccine type for both.

Health - Pharmacology - 02.07.2021
Cancer: immunotherapies without side effects?
Cancer: immunotherapies without side effects?
By identifying the mechanism of toxicity induced by immunotherapies, scientists from the University of Geneva and from the Harvard Medical School are paving the way for cancer treatments with fewer side effects. In recent years, immunotherapy has revolutionised the field of cancer treatment. However, inflammatory reactions in healthy tissues frequently trigger side effects that can be serious and lead to the permanent discontinuation of treatment.

Health - Pharmacology - 02.07.2021
Detecting oesophageal cancer with AI
Detecting oesophageal cancer with AI
Experts at UCL and spinout company Odin Vision working with clinicians at UCLH have used artificial intelligence (AI) to help detect early signs of oesophageal cancer. The first procedure in the world using the AI technology was performed at University College Hospital by UCLH consultant gastroenterologist Dr Rehan Haidry.

Pharmacology - Health - 02.07.2021
Aspirin could cut risk of death in cancer patients by 20%, major review of studies suggests
Patients with a wide range of cancers who take aspirin as part of their treatment could help to reduce their risk of death by 20%, a major review of existing research has suggested. Academics at Cardiff University carried out a systematic review of 118 published observational studies in patients with 18 different cancers.

Pharmacology - Psychology - 01.07.2021
Autistic individuals may be more likely to use recreational drugs to self-medicate their mental health
Autistic individuals may be more likely to use recreational drugs to self-medicate their mental health
While autistic individuals are less likely to use substances, those who do so are more likely to self-medicate for their mental health symptoms, according to new research from the University of Cambridge and published today in The Lancet Psychiatry .

Health - Pharmacology - 30.06.2021
Scientists identify 160 new drugs that could be repurposed against COVID-19
Scientists identify 160 new drugs that could be repurposed against COVID-19
Cambridge scientists have identified 200 approved drugs predicted to work against COVID-19 - of which only 40 are currently being tested in COVID-19 clinical trials. We hope this resource of potential drugs will accelerate the development of new drugs against COVID-19.

Health - Pharmacology - 30.06.2021
Ethnic disparities in statin treatment may lead to more heart attacks and strokes
People of South Asian and African/ African Caribbean ethnicity who have type 2 diabetes are less likely to be prescribed statins than those of European ethnicity, potentially contributing to thousands of preventable heart attacks and strokes each year, finds a new UCL-led study. The study, published in the open access journal PLOS Medicine and funded by Diabetes UK, used a database of 12 million anonymised national health records to look at rates of statin prescribing for people newly diagnosed with type 2 diabetes who were also eligible for statins.