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Results 61 - 80 of 2789.


Health - Pharmacology - 05.12.2024
Spleen stiffness as a key to the diagnosis of portal hypertension
Advanced liver disease is the second most common cause of lost working years, as it disproportionately affects young patients. Possible complications of these diseases can often be traced back to high blood pressure in the blood circulation of the liver - portal hypertension. Under the leadership of Mattias Mandorfer from the Clinical Division of Gastroenterology and Hepatology at MedUni Vienna and University Hospital Vienna, the NICER model has now been developed, which can calculate the percentage probability of the presence of portal hypertension without an invasive procedure.

Health - Pharmacology - 04.12.2024
How the latest sensors analyse body fluids
How the latest sensors analyse body fluids
A new generation of wearable sensors will fundamentally change medicine. Researchers at ETH Zurich have now published an overview showing what is possible with such sensors and what questions their developers should consider to ensure their successful future use. Using a smartwatch to measure pulse, and a smartphone app to monitor blood pressure: wearable sensors already track some of the body's vital functions fairly reliably, and some of these devices can already be used in clinical diagnostics.

Life Sciences - Pharmacology - 04.12.2024
CRISPR-Cas technology: balancing efficiency and safety
CRISPR-Cas technology: balancing efficiency and safety
Researchers have uncovered a serious side effect of using the CRISPR-Cas gene scissors. A molecule designed to make the process more efficient destroys parts of the genome. Genome editing with various CRISPR-Cas molecule complexes has progressed rapidly in recent years. Hundreds of labs around the world are now working to put these tools to clinical use and are continuously advancing them.

Health - Pharmacology - 29.11.2024
Global review charts lethal impact of fungal infection after lung disease
Around 32% of people who have had prior damage from lung diseases will die after five years if they also get a common fungal infection, a major global review has found. The review also finds that 15% of people with chronic pulmonary aspergillosis (CPA) die in the first year following other lung diseases.

Health - Pharmacology - 29.11.2024
Killing two birds with one stone
An affordable and effective nutritional approach to help reduce inflammation and prevent Type 2 diabetes. The team led by May Faraj, Professor of Nutrition at Université de Montréal and Director of the Nutrition, Lipoproteins and Cardiometabolic Diseases Research Unit at the Montréal Clinical Research Institute (IRCM), sheds new light on the role of marine-source omega-3 supplementation in treating adipose tissue inflammation and reducing the risk for cardiometabolic diseases like Type 2 diabetes.

Health - Pharmacology - 29.11.2024
Scientists expose cells driving aggressive tumour growth
The first computer algorithm capable of identifying which tumour cells are driving aggressive cancer growth has been developed by Cancer Research scientists from UCL and The Francis Crick Institute. The innovative algorithm, called SPRINTER*, analyses individual cells within a tumour to identify those that are growing the most rapidly.

Pharmacology - 27.11.2024
Cutting-edge contact lens gel delivers medication
Cutting-edge contact lens gel delivers medication
The next time you need to take a prescription drug, taking it might be as easy as putting on a contact lens, thanks to a new discovery made by University of Waterloo researchers. The team of researchers - which spans Waterloo's Department of Chemistry and its School of Optometry and Vision Science - created a new type of hydrogel that can deliver drugs to patients with various eye issues when 3D printed onto a contact lens.

Health - Pharmacology - 25.11.2024
New form of a rare disease discovered
Secondary lymphoid organs are specialised structures in the body in which immune cells multiply and develop to respond to new pathogens such as viruses and bacteria. An international team led by Kaan Boztug (St. Anna Children's Cancer Research, MedUni Vienna, CeMM) has now been able to identify a completely new form of a rare disease that provides a better understanding of the importance of these structures for the human immune system.

Pharmacology - Health - 22.11.2024
A Groundbreaking New Approach to Treating Chronic Abdominal Pain
A Groundbreaking New Approach to Treating Chronic Abdominal Pain
Researchers at the University of Vienna develop gut-stable oxytocin analogues for targeted pain treatment of chronic abdominal pain A research team at the University of Vienna, led by medicinal chemist Markus Muttenthaler, has developed a new class of oral peptide therapeutic leads for treating chronic abdominal pain.

Health - Pharmacology - 21.11.2024
Researchers Wear Purple on World Pancreatic Cancer Day to Raise Awareness About Deadly Disease
VUB Researchers Wear Purple on World Pancreatic Cancer Day to Raise Awareness About Deadly Disease Brussels, November 21, 2024 - Today marks World Pancreatic Cancer Day.

Health - Pharmacology - 21.11.2024
Parkinson's drug changes the gut microbiome for the worse due to iron deficiency
Parkinson’s drug changes the gut microbiome for the worse due to iron deficiency
Disruption of the microbial community favours pathogens in the gut In a groundbreaking new study, conducted within the framework of the FWF-funded Cluster of Excellence "Microbiomes drive Planetary Health", scientists from the University of Vienna, in collaboration with the University of Southampton, Aalborg University and Boston University, have revealed that the widely prescribed Parkinson's disease drug entacapone significantly disrupts the human gut microbiome by inducing iron deficiency.

Pharmacology - Health - 21.11.2024
New approach to personalized treatment of rheumatoid arthritis
New approach to personalized treatment of rheumatoid arthritis
A large number of effective drugs are currently available for the treatment of rheumatoid arthritis, but until now there has been a lack of suitable strategies for choosing the best possible therapy for individual patients. In a comprehensive scientific review led by rheumatologist Daniel Aletaha, Head of the Department of Medicine III at MedUni Vienna, a model has now been developed that focuses on the individual needs of patients and their health situation.

Pharmacology - Life Sciences - 20.11.2024
A bioinspired capsule can pump drugs directly into the walls of the GI tract
A bioinspired capsule can pump drugs directly into the walls of the GI tract
The needle-free device could be used to deliver insulin, antibodies, RNA, or other large molecules. Inspired by the way that squids use jets to propel themselves through the ocean and shoot ink clouds, researchers from MIT and Novo Nordisk have developed an ingestible capsule that releases a burst of drugs directly into the wall of the stomach or other organs of the digestive tract.

Psychology - Pharmacology - 18.11.2024
Multiple sclerosis drug may help with poor working memory
Fampridine is currently used to improve walking ability in multiple sclerosis. A new study shows that it could also help individuals with reduced working memory, as seen in mental health conditions like schizophrenia or depression. Remembering a code for long enough to type it in; holding a conversation and reacting appropriately to what is being said: in everyday situations like these, we use our working memory.

Pharmacology - Health - 18.11.2024
New oral drug to calm abdominal pain
University of Queensland researchers have developed a new class of oral painkillers to suppress chronic abdominal pain that is based on the peptide hormone oxytocin that drives childbirth contractions. Associate Professor Markus Muttenthaler from UQ's Institute for Molecular Bioscience led a team that has changed the chemical structure of oxytocin to make it gut-stable after earlier work revealed the hormone could treat abdominal pain.

Health - Pharmacology - 15.11.2024
Novel Model Enables Research of Individual Immune Responses for Colorectal Cancer
Predicting the optimal therapy for individual cancer patients is one of the most important goals of modern medicine. A MedUni Vienna research team led by Michael Bergmann (Department of General Surgery, MedUni Vienna/AKH Wien) and Matthias Farlik (Department of Dermatology, MedUni Vienna/AKH Wien) has now developed a model system for culturing individual colorectal cancer patient samples that include cancer cells as well as structural and immune cells.

Health - Pharmacology - 13.11.2024
New study suggests weight loss drugs like Ozempic could help with knee pain
Originally developed to help people with type 2 diabetes manage blood sugar, the drug semaglutide, commonly known by the brand names Ozempic or Wegovy, has shown promise for other health issues as well. University of Sydney researchers explain how. Clinical trials show semaglutide can be effective for  weight loss , and hundreds of thousands of people around the world are using it  for this purpose.

Health - Pharmacology - 12.11.2024
How Immune Cells 'Sniff Out' Pathogens
How Immune Cells ’Sniff Out’ Pathogens
Researchers from the University of Bonn are using an innovative method to watch immune receptors go about their business Immune cells are capable of detecting infections just like a sniffer dog, using special sensors known as Toll-like receptors, or TLRs for short. But what signals activate TLRs, and what is the relationship between the scale and nature of this activation and the substance being detected? In a recent study, researchers from the University of Bonn and the University Hospital Bonn (UKB) used an innovative method to answer these questions.

Health - Pharmacology - 12.11.2024
Glioblastoma: new treatment attacks brain tumors from multiple angles
Glioblastoma: new treatment attacks brain tumors from multiple angles
Glioblastoma is the most common kind of malignant brain tumor in adults. So far, no treatment has been able to make this aggressive tumor permanently disappear. The tumor cells are too varied, and the microenvironment is too tumor-friendly. Researchers at the University of Basel and University Hospital Basel have now developed an immunotherapy that not only attacks the tumor-it also turns its microenvironment against it.

Pharmacology - Health - 12.11.2024
'Sleepy cannabis': first objective study to show cannabinol increases sleep
’Sleepy cannabis’: first objective study to show cannabinol increases sleep
Research at the University of Sydney Lambert Initiative shows that cannabinol increases both REM and non-REM sleep in rats. Human trials are now under way. Research by scientists at the University of Sydney has identified a constituent in the cannabis plant that improves sleep. Their report is the first to use objective measures to show the component, known as cannabinol (CBN), increases sleep in rats.