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Results 81 - 100 of 1377.


Health - Pharmacology - 25.05.2021
Metabolic hormone ’leptin’ linked to vaccine response
Reduced levels of a metabolic hormone known as leptin is linked to poor vaccine antibody responses in the general population, a University of Queensland study has found. The researchers made the discovery while investigating several cohorts' responses to the influenza vaccine or hepatitis B vaccine pre-COVID.

Life Sciences - Pharmacology - 25.05.2021
Racemases: The hunt for drugs to neutralise these critical enzymes
Racemases: The hunt for drugs to neutralise these critical enzymes
Bath scientists explore racemases and propose strategies for finding drugs that target these important enzymes. Last updated on Tuesday 25 May 2021 Bath academics explore racemases - an important type of enzyme that is linked to certain cancers and other life-threatening diseases while also being critical to cell function - in a paper published in the prestigious journal Chemical Society Reviews.

Health - Pharmacology - 21.05.2021
Vast undertreatment of diabetes seen in global study
Only 1 in 10 people with diabetes in lowand middle-income countries is getting evidence-based, low-cost comprehensive care Nearly half a billion people on the planet have diabetes, but most of them aren't getting the kind of care that could make their lives healthier, longer and more productive, according to a new global study of data from people with the condition.

Pharmacology - Health - 20.05.2021
Older Adults with Functional Impairments Linked to Prescription Drug Use/Misuse
Study finds adults age 50 and older with functional impairments at higher risk of medical cannabis use, as well as prescription opioid and tranquilizer/sedative use and misuse According to the Centers for Disease Control and Prevention, approximately 22 percent of older adults in the United States suffer from a functional impairment, defined as difficulties performing daily activities, such as bathing or getting dressed, or problems with concentration or decision-making affected by physical, mental or emotional conditions.

Health - Pharmacology - 20.05.2021
Opinion: The danger of journals being seen as substitute regulators
The Covid-19 pandemic has highlighted the risks associated with seeing journals as authoritative voices on the safety and effectiveness of vaccines, says Dr Chris Van Tulleken (UCL Infection & Immunity). A superficial reading of the history of vaccination might lead you to believe that it is simple.

Health - Pharmacology - 19.05.2021
Cardiologist calls for increased prevention of high blood pressure
Cardiologist calls for increased prevention of high blood pressure
Wednesday, May 19, 2021 — The annual World Hypertension Day on 17 May prompted the publication of a review article on hypertension that appears today in the leading journal The Lancet. In this article, Prof Sofie Brouwers, OLV Ziekenhuis Aalst and Vrije Universiteit Brussel, and her colleagues present the current state of affairs regarding arterial hypertension.

Pharmacology - Life Sciences - 19.05.2021
Development of a peptide that allows cannabis-derived drugs to relieve pain without side effects
Scientists from the Proteomics and Protein Chemistry Research Group and the Neuropharmacology-Neurophar Laboratory have developed a peptide which is an ideal candidate for reducing the cognitive side effects of pain treatment with cannabis derivatives. An international team, led by researchers from UPF David Andreu and Rafael Maldonado , has developed a peptides family that allows delta-9-tetrahydrocannabinol (THC), the main component of Cannabis sativa , to fight pain in mice without side effects.

Health - Pharmacology - 18.05.2021
New Technology Makes Tumor Eliminate Itself
New Technology Makes Tumor Eliminate Itself
A new technology enables the body to produce therapeutic agents on demand at the exact location where they are needed. The innovation could reduce the side effects of cancer therapy and may hold the solution to better delivery of Covid-related therapies directly to the lungs. Scientists at the University of Zurich have modified a common respiratory virus, called adenovirus, to act like a Trojan horse to deliver genes for cancer therapeutics directly into tumor cells.

Health - Pharmacology - 17.05.2021
Encouraging sign: Many California prisoners willing to be vaccinated
Two-thirds of the nearly 100,000 incarcerated residents in California's 35 prisons were offered COVID-19 vaccines and 66.5% of those accepted at least one dose, according to a new Stanford study - although uptake varied across different groups. Two-thirds of California prisoners who were offered a COVID-19 vaccine accepted at least one dose, according to a new study by researchers at the Stanford University School of Medicine.

Health - Pharmacology - 17.05.2021
Commonly Used Drugs for Schizophrenia Linked to Greater Cognitive Impairment
Medications with anticholinergic properties are often key parts of treatment, but may worsen brain functioning Writing in the May 14, 2021 issue of The American Journal of Psychiatry , a multi-institution team of scientists led by researchers at University of California San Diego School of Medicine report that medications commonly prescribed to reduce the severity of physical and mental health symptoms associated with schizophrenia may have a cumulative effect of worsening cognitive function in patients.

Health - Pharmacology - 14.05.2021
New immunotherapy 'highly effective' against hepatitis B virus
New immunotherapy ’highly effective’ against hepatitis B virus
Scientists at UCL have identified a new immunotherapy to combat the hepatitis B virus (HBV), the most common cause of liver cancer in the world. Each year, globally, chronic HBV causes an estimated 880,000 deaths from liver cirrhosis and hepatocellular carcinoma/liver cancer (HCC). The pioneering study used immune cells isolated directly from patient liver and tumour tissue ,  to show that targeting acyl-CoA:cholesterol acyltransferase (ACAT), an enzyme that helps to manage cholesterol levels in cells*, was highly effective at boosting immune responses.

Health - Pharmacology - 14.05.2021
New imaging technique could lead to better bio-implants for patients
University of Birmingham scientists have developed a new microscopic imaging approach to take a closer look at 3D-printing for developing future patient implants, as well as improved disease modelling and drug screening. Additive manufacturing (3D printing) platforms create bioprinted structures by moving a special bioink, containing cells, biomolecules and materials, through a narrow tube, but the process can result in cells becoming damaged as they pass through the tiny tube.

Health - Pharmacology - 13.05.2021
Screening for ovarian cancer did not reduce deaths
A large-scale randomised trial of annual screening for ovarian cancer, led by UCL researchers, did not succeed in reducing deaths from the disease, despite one of the screening methods tested detecting cancers earlier. Results from the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS) have been published in a report in the medical journal The Lancet .

Pharmacology - 13.05.2021
Childhood abdominal pain may be linked to disordered eating in teenagers | University of Oxford
New research shows that people who suffer from recurrent abdominal pain in childhood may be more likely to have disordered eating as teenagers. This is the first study to provide prospective evidence of an association between recurrent abdominal pain at aged 7-9 years and fasting to control weight at aged 16 years.

Health - Pharmacology - 11.05.2021
Gene therapy offers potential cure to children born without an immune system
Study shows treatment developed by international team restored immune function in more than 95% of patients in three clinical trials Study shows treatment developed by international team restored immune function in more than 95% of patients in three clinical trials An experimental form of gene therapy developed by a team of researchers from UCLA and Great Ormond Street Hospital in London has successfully treated 48 of 50 children born with a rare and deadly inherited disorder that leaves them without an immune system.

Health - Pharmacology - 10.05.2021
TB immune response discovery could significantly reduce disease harm
TB immune response discovery could significantly reduce disease harm
A pioneering study by UCL scientists has discovered the presence of a harmful inflammatory protein in patients with symptomatic tuberculosis (TB). Researchers say, by targeting the IL-17 cytokine, a component produced naturally by the immune system in response to infection, excessive and damaging lung inflammation caused by TB may be significantly reduced to help speed up patient recovery.

Pharmacology - Chemistry - 10.05.2021
New, Promising Ways of Fighting Viruses
New, Promising Ways of Fighting Viruses
A research team including scientists from Freie Universität Berlin is investigating novel antiviral drugs that can also inhibit the spread of coronaviruses No 086/2021 from May 10, 2021 Researchers from the Institute of Pharmacy at Freie Universität Berlin, in collaboration with researchers at Katholieke Universiteit Leuven, have discovered a new process for developing antiviral agents for drugs.

Health - Pharmacology - 06.05.2021
Biomarker Detects Severe COVID-19 Early On
Severe cases of COVID-19 can now be detected at an early stage. Researchers at the University of Zurich have identified the first biomarker that can reliably predict which patients will develop severe symptoms. This can help to improve the treatment of severe cases of COVID-19. Most people who are infected with SARS-CoV-2 develop no or only mild symptoms.

Social Sciences - Pharmacology - 05.05.2021
The first step to curbing COVID vaccine misinformation is finding out who is most vulnerable
The success of Australia's COVID-19 vaccine rollout will depend on everyone's willingness to receive it. But experts have warned vaccine misinformation online puts Australia's communities at risk, and some more than others. Often, misinformation and undue scepticism are spread on social media. In March, the ABC reported on WeChat posts spreading the false claim the Pfizer vaccine can integrate with people's DNA to transform them into "genetically modified humans'.

Pharmacology - Social Sciences - 05.05.2021
Vaccine rollout not going well, say most Australians
Almost two-thirds of adult Australians, 64 per cent, think the Government's COVID-19 vaccine rollout is not being handled well, a study from The Australian National University (ANU) shows. The study also found there's been a small decline in the proportion of people who would not take a safe and effective vaccine, though many Australians remain highly concerned about potential side effects.