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Pharmacology
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Health - Pharmacology - 15.11.2024
Novel Model Enables Research of Individual Immune Responses for Colorectal Cancer
Predicting the optimal therapy for individual cancer patients is one of the most important goals of modern medicine. A MedUni Vienna research team led by Michael Bergmann (Department of General Surgery, MedUni Vienna/AKH Wien) and Matthias Farlik (Department of Dermatology, MedUni Vienna/AKH Wien) has now developed a model system for culturing individual colorectal cancer patient samples that include cancer cells as well as structural and immune cells.
Health - Pharmacology - 13.11.2024
New study suggests weight loss drugs like Ozempic could help with knee pain
Originally developed to help people with type 2 diabetes manage blood sugar, the drug semaglutide, commonly known by the brand names Ozempic or Wegovy, has shown promise for other health issues as well. University of Sydney researchers explain how. Clinical trials show semaglutide can be effective for weight loss , and hundreds of thousands of people around the world are using it for this purpose.
Health - Pharmacology - 12.11.2024

Researchers from the University of Bonn are using an innovative method to watch immune receptors go about their business Immune cells are capable of detecting infections just like a sniffer dog, using special sensors known as Toll-like receptors, or TLRs for short. But what signals activate TLRs, and what is the relationship between the scale and nature of this activation and the substance being detected? In a recent study, researchers from the University of Bonn and the University Hospital Bonn (UKB) used an innovative method to answer these questions.
Health - Pharmacology - 12.11.2024

Glioblastoma is the most common kind of malignant brain tumor in adults. So far, no treatment has been able to make this aggressive tumor permanently disappear. The tumor cells are too varied, and the microenvironment is too tumor-friendly. Researchers at the University of Basel and University Hospital Basel have now developed an immunotherapy that not only attacks the tumor-it also turns its microenvironment against it.
Pharmacology - Health - 12.11.2024

Research at the University of Sydney Lambert Initiative shows that cannabinol increases both REM and non-REM sleep in rats. Human trials are now under way. Research by scientists at the University of Sydney has identified a constituent in the cannabis plant that improves sleep. Their report is the first to use objective measures to show the component, known as cannabinol (CBN), increases sleep in rats.
Pharmacology - Health - 06.11.2024

A new international study spanning the United Kingdom, United States, and Canada has revealed important insights into the risks associated with prescribed opioid use for noncancer pain. The research, led by researchers at The University of Manchester and McGill University in Canada which analysed over 1 million patients newly initiated on opioids, found prescription of strong opioids was associated with higher risk of all-cause mortality compared to taking codeine.
Health - Pharmacology - 06.11.2024
Tailor-made treatments for ultra-rare disease patients
In a new study, a team of researchers, including Anneliene Jonker, has published the first roadmap for developing genetic therapies for ultra-rare diseases. These conditions affect only one person worldwide and stem from unique genetic mutations. This breakthrough provides hope to millions worldwide who suffer from extremely rare genetic disorders for which no targeted treatments were previously available.
Pharmacology - Health - 06.11.2024
COVID-19: Real-world effectiveness of antiviral drugs investigated
In a study led by MedUni Vienna, data from more than 100,000 patients with a confirmed SARS-CoV-2 infection who were registered with the Vienna City Health Service around two years ago was analysed. Of these, more than 20,000 patients were treated with antiviral drugs due to their risk of a severe course.
Pharmacology - Health - 05.11.2024

Researchers have found a new way to use biocatalysis to improve the production of critical raw materials required for essential drugs, making the process quicker, more efficient, and environmentally friendly. Biocatalysis is a process that uses enzymes as natural catalysts to carry out chemical reactions.
Pharmacology - Health - 05.11.2024
New active substance for the treatment of acute sudden hearing loss
A research team led by MedUni Vienna has investigated AC102, a new active substance that offers hope of an effective treatment for acute sudden hearing loss. The latest results have been published in the scientific journal "Cell Death & Disease". Initial findings from preclinical trials could represent a significant advancement in the treatment of acute hearing disorders.
Pharmacology - Chemistry - 04.11.2024

An international team of researchers have developed a promising new drug which could help combat the spread of treatment-resistant malaria. The breakthrough development is the first to adapt an approach from cancer treatments to tackle malaria. It works by permanently disabling a protein that Plasmodium falciparum , one of the mosquito-borne parasites which spreads malaria, uses to duplicate itself inside the human body.
Health - Pharmacology - 30.10.2024

Unsplash Teams from the departments of clinical and biological hematology, obstetrics and gynecology, pharmacovigilance, medical intensive care, infectiology, as well as the clinical research unit of theHôpital Cochin-Port Royal AP-HP, Université Paris Cité, Inserm and the HEMAPREG network, coordinated by Mr Pierre Pinson and Drs Ismael Boussaid and Rudy Birsen, have conducted a study on pregnancy-associated hematological cancers.
Pharmacology - Health - 30.10.2024

In a recent study, an international research team with significant involvement from MedUni Vienna has investigated how nanoplastic particles deposited in the body affect the effectiveness of antibiotics. The study showed that the plastic particles not only impair the effect of the drugs, but could also promote the development of antibiotic-resistant bacteria.
Health - Pharmacology - 30.10.2024

First-of-its-kind Canadian study found 10 Ontario children died of an opioid-related cause between 2017 and 2021 A new study from Western researchers in collaboration with the Office of the Chief Coroner of Ontario highlights the scope of opioid-related deaths in young children in Ontario, while providing a clearer picture of the risk factors.
Health - Pharmacology - 28.10.2024

Western researchers are taking a unique global approach to finding an effective treatment for people living with long COVID. Led by Schulich School of Medicine & Dentistry professor Douglas Fraser, the projects represent the first multi-continental research conducted on long COVID, with study sites in Africa and North and South Americas.
Health - Pharmacology - 28.10.2024

Head and neck cancers are among the ten most common cancers worldwide. Head and neck tumors account for about three to five percent of all cancers, with squamous cell carcinomas being the predominant form. They occur in areas such as the oral cavity, pharynx and larynx. An international team of researchers led by Sara Wickström has now developed a new technique that allows the properties of cancer cells and their surrounding tissue to be analyzed in detail at the single-cell level.
Life Sciences - Pharmacology - 25.10.2024

US researchers have participated in a study that reveals how alterations in brain development in psychosis may be related to metabolism and neurotransmitters. Researchers from the University of Seville have participated, together with representatives from other Spanish, British, American and Canadian research centers, in a recent scientific study that has identified important anomalies in the brain maturation of individuals with psychosis.
Pharmacology - Health - 25.10.2024
Stroke patients could benefit from earlier blood thinning treatment
People with atrial fibrillation (AF) who have a stroke could benefit from blood thinning treatments, known as anticoagulants, at an earlier stage than is currently recommended, finds a new study led by UCL researchers. Results from the British Heart Foundation funded OPTIMAS study are published in the Lancet and presented at the World Stroke Congress 2024.
Health - Pharmacology - 25.10.2024

Nearly three quarters of new non-cancer pain opioid prescriptions were for patients with musculoskeletal conditions, despite limited evidence of the drug's efficacy, according to the largest UK study of its kind. The new study , also the first of its kind in the UK, evaluated the specific clinical conditions that lead to the initiation of opioid prescriptions using data from nationally representative GP electronic health records.
Health - Pharmacology - 25.10.2024

FINDINGS UCLA scientists have identified the protein GPNMB as a critical regulator in the heart's healing process after a heart attack. Using animal models, they demonstrate that bone marrow-derived immune cells called macrophages secrete GPNMB, which binds to the receptor GPR39, promoting heart repair.
Environment - Feb 18
A UB campaign analyses the impact of microplastics on marine fauna in Antarctica
A UB campaign analyses the impact of microplastics on marine fauna in Antarctica

Environment - Feb 18
Expert Comment: Can the UK deliver the carbon storage needed to meet climate goals without taxpayer billions?
Expert Comment: Can the UK deliver the carbon storage needed to meet climate goals without taxpayer billions?
Environment - Feb 18
Mobile water laboratory at Leipzig University supports WHO on the island of Mayotte
Mobile water laboratory at Leipzig University supports WHO on the island of Mayotte

Health - Feb 17
The UB confers honorary doctorates on Harry C. Dietz and Bart L. Loeys, experts on Marfan and Loeys-Dietz syndromes
The UB confers honorary doctorates on Harry C. Dietz and Bart L. Loeys, experts on Marfan and Loeys-Dietz syndromes
