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Health - 09.09.2019
Glass down, FASD awareness turned up
Most Australians know it is unsafe to drink during pregnancy, but researchers say the number of children with lifelong impacts from Fetal Alcohol Spectrum Disorder (FASD) remains far too high.

Health - 07.09.2019
Researchers lead new national guidance on how to stay fit and healthy
Researchers lead new national guidance on how to stay fit and healthy
Guidance on how the UK population can stay fit and healthy has been updated thanks to a major review led by the University of Bristol. The physical activity guidelines issued today by the four Chief Medical Officers (CMOs) of England, Scotland, Wales and Northern Ireland, offer advice to all age groups and - for the first time - pregnant women, new mums and disabled adults.

Pharmacology - Health - 06.09.2019
European Commission approves Roche’s Tecentriq in combination with chemotherapy for the initial treatment of people with extensive-stage small cell lung cancer
Tecentriq in combination with chemotherapy (carboplatin and etoposide) is the first and only cancer immunotherapy approved by the European Medicines Agency for the initial treatment of extensive-stag

Health - 05.09.2019
Vontobel Award: Systematic Remembering and Similar Surgical Consequences
This year's Vontobel Award for Research on Age(ing) goes to Burcu Demiray Batur from the University of Zurich, Jonathan Rychen from the University Hospital of Basel and Sarah Stricker from the Hôpital Necker in Paris.

Innovation - Health - 04.09.2019
UCLA and Theseus AI announce license agreement for technology that interprets spine MRIs
UCLA signed a license agreement with Theseus AI for technology developed at UCLA that uses artificial intelligence to interpret MRI scans of patients' spines.

Pharmacology - Health - 04.09.2019
Roche to present pivotal data for satralizumab in neuromyelitis optica spectrum disorder and six-year OCREVUS data in multiple sclerosis at ECTRIMS
Investigational medicine satralizumab significantly reduces the risk of relapse in pivotal SAkuraStar monotherapy study for neuromyelitis optica spectrum disorder New data provide insights into neuro

Health - Physics - 03.09.2019
EU Funding for Research at TUM
EU Funding for Research at TUM
The European Research Council (ERC) has announced that seven of its ERC Starting Grants will be awarded to scientists at the Technical University of Munich (TUM) this year.

Health - Pharmacology - 03.09.2019
Poor diet can lead to blindness
An extreme case of "fussy" or "picky" eating caused a young patient's blindness, according to a new case report published today [2 Sep 2019] in Annals of Internal Medicine.

Environment - Health - 03.09.2019
Poverty as a disease trap
Poverty as a disease trap
The realities of subsistence living in a region of Senegal hard hit by schistosomiasis make reinfection likely, despite mass drug administration. Stanford researchers find that engaging communities in the design of disease control programs could help. No drug can cure a paradox. That basic truth is at the heart of a new Stanford-led study highlighting how poverty traps make it impossible to eradicate a potentially deadly disease with current approaches.

Pharmacology - Health - 02.09.2019
Entresto improved measures of heart structure and function in HFrEF patients in new Novartis study; additional data complement findings
Results from PROVE-HF trial show significant improvements in measures of cardiac structure and function at six months and one year in heart failure with reduced ejection fraction (HFrEF) patients ; EVALUATE-HF results complement findings   PROVE-HF establishes significant correlation between improvement in widely used cardiac biomarker and positive changes in heart structure and ability to pump blood in patients taking Entresto   Safety and tole

Health - Innovation - 02.09.2019
Preventing asthma attacks: a father's fight for his daughter
Preventing asthma attacks: a father’s fight for his daughter
An asthma attack took Thea Notaras' life two weeks before her 17th birthday. Now her father is working to save others from her fate.

Health - Pharmacology - 02.09.2019
Positive phase III results show Xofluza reduces risk of developing flu after contact with an infected person by 86%
BLOCKSTONE study reaches primary endpoint of fewer people testing positive for flu, with fever and at least one respiratory symptom, when treated with Xofluza versus placebo Xofluza may represent an

Pharmacology - Health - 02.09.2019
Roche presents positive phase III study results for one-dose Xofluza in children with flu
Phase III MINISTONE-2 data are consistent with known safety profile of Xofluza (baloxavir marboxil) in children and show comparable efficacy to oseltamivir Xofluza was administered as a new one-dose

Pharmacology - Health - 01.09.2019
Novartis PARAGON-HF trial suggests Entresto benefit in HFpEF patients but narrowly misses primary endpoint
Entresto (sacubitril/valsartan) reduced the composite of total (first and recurrent) heart failure hospitalizations and cardiovascular death although narrowly missed statistical significance (p = 0.059)   Totality of evidence, including improvement in various measures of symptoms, quality of life, and renal function, suggests clinically important benefits in HFpEF   Entresto was well tolerated and the overall safety profile was comparable

Pharmacology - Health - 01.09.2019
Preserved Heart Failure Trial Misses Endpoint, But Drug May Benefit Some Patients
The number of patients with heart failure with preserved ejection fraction is on the rise, and the search is on for a therapy that can improve health outcomes in this group of patients for whom no approved therapies are available.

Linguistics / Literature - Health - 31.08.2019

Health - Social Sciences - 30.08.2019
Summertime at Stanford - a time for two rising seniors to do gender-related research
Summertime at Stanford - a time for two rising seniors to do gender-related research
As Susan Heck Interns, Julia Pandolfo and Sophia Hu spent the summer working full time on their individual research projects at the Clayman Institute for Gender Research.

Health - Materials Science - 30.08.2019
Medicine for tomorrow
How can the latest findings from materials science be used in medical practice to develop innovative diagnostic and therapeutic concepts' Empa researchers, physicians from the Cantonal Hospital of St

Pharmacology - Health - 30.08.2019
Novartis ofatumumab demonstrates superiority versus Aubagio in two head-to-head Phase III multiple sclerosis studies
In ASCLEPIOS I and II, ofatumumab (OMB157) met primary endpoints to reduce the annualized relapse rate over Aubagio * (teriflunomide) in patients with relapsing forms of MS (RMS) Key secondary endpoi

Health - Pharmacology - 29.08.2019

Pharmacology - Health - 29.08.2019
European Commission approves Roche’s Tecentriq in combination with Abraxane for people with PD-L1-positive, metastatic triple-negative breast cancer
The Tecentriq combination marks the first cancer immunotherapy regimen to be available in Europe for triple-negative breast cancer - an aggressive and difficult-to-treat disease Approval based on the

Pharmacology - Health - 29.08.2019
Roche launches VENTANA PD-L1 (SP142) Assay in CE markets as first companion diagnostic to identify triple-negative breast cancer patients eligible for treatment with Tecentriq
This launch represents an important step in Roche's personalised healthcare strategy to fit treatments to patients who can benefit most from a specific medicine Each year 300,000 patients around the

Pharmacology - Health - 28.08.2019
New patient test could tell GPs if infections are antibiotic resistant in under two hours
New patient test could tell GPs if infections are antibiotic resistant in under two hours
A new rapid patient test which could identify whether bacteria isolated from clinical samples are antibiotic resistant in under two hours is being trialled on a range of antibiotics commonly used to treat urinary tract infections (UTIs).

Health - Materials Science - 26.08.2019
3D printed salt template for bioresorbable bone implants
3D printed salt template for bioresorbable bone implants
With the help of a 3D printed salt template, ETH researchers have succeeded in producing magnesium scaffolds with structured porosity that are suitable for bioresorbable bone implants. For the treatment of complex bone fractures or even missing bone parts, surgeons typically deploy metal implants. In this context, an attractive alternative to the traditional materials like bioinert titanium are biodegradable magnesium and its alloys.

Health - 26.08.2019
Exoskeleton Research Takes Steps Forward, Thanks To Personal Connection
John Mangual grew up watching his mother limp. Amy Mangual had broken her leg, and lived with ligament and tendon problems that lead to chronic ankle instability.

Chemistry - Health - 25.08.2019
Chemist James Trudell, whose research led to greater understanding of anesthetics, dies
For five decades, James Trudell studied how anesthetics work on the human body to cause unconsciousness. James Trudell, PhD, a Stanford Medicine chemist who spent 50 years hunting down molecular clues to help make anesthetic drugs safer for patients, died July 29 at his home in Woodside, California, with his wife by his side.

Health - Life Sciences - 21.08.2019
Mechanical forces impact immune response in the lungs
When the body is fending off an infection, there are changes in temperature, pH balance, and metabolism. Yale researchers wondered if yet other factors might come into play, and in a recent study, confirmed that mechanical forces also influence the immune response. The research team explored the matter by focusing on studies of the lungs where breathing creates pressure inside tiny airs sacs called alveoli.

Health - Innovation - 20.08.2019
ICR joins Imperial’s Academic Health Science Centre partnership
The Institute of Cancer Research, London, has joined the Imperial College Academic Health Science Centre (AHSC).

Innovation - Health - 20.08.2019
3D printing of silicone components
3D printing of silicone components
ETH spin-off Spectroplast has developed a method to make silicone products using a 3D printer. The young company now plans to bring to market customised medical products such as hearing aids, breast prosthesis for breast cancer patients and eventually even artificial heart valves.

Pharmacology - Health - 19.08.2019
Novartis to present new Entresto HFpEF and HFrEF data at ESC Congress 2019
PARAGON-HF trial will provide Entresto (sacubitril/valsartan) Phase III full results in heart failure with preserved ejection fraction (HFpEF)   New PROVE-HF and EVALUATE-HF studies will highlight Entresto's direct impact on the heart in heart failure with reduced ejection fraction (HFrEF)   New PIONEER-HF and TRANSITION-HF findings will advance understanding of Entresto use in patients hospitalized for decompensated HFrEF following stabilizatio

Health - Innovation - 19.08.2019

Pharmacology - Health - 16.08.2019
FDA approves Roche’s Rozlytrek (entrectinib) for people with ROS1-positive, metastatic non-small cell lung cancer and NTRK gene fusion-positive solid tumours
First FDA-approved treatment designed to target both ROS1 and NTRK that also shows response in cancer that has spread to the brain Roche's first FDA-approved tumour-agnostic medicine Roche today announced that the US Food and Drug Administration (FDA) has approved Rozlytrek?

Pharmacology - Health - 16.08.2019
FDA approves Roche’s RozlytrekTM (entrectinib) for people with ROS1-positive, metastatic non-small cell lung cancer and NTRK gene fusion-positive solid tumours
First FDA-approved treatment designed to target both ROS1 and NTRK that also shows response in cancer that has spread to the brain Roche's first FDA-approved tumour-agnostic medicine Roche today announced that the US Food and Drug Administration (FDA) has approved Rozlytrek?

Health - Life Sciences - 15.08.2019
Major award for two Bernese medical projects
Major award for two Bernese medical projects
Prestigious grants from the USA go to two Bernese researchers: the biomedical scientists Marianna Kruithof-de Julio and Robert Rieben were the only researchers in Switzerland to receive a grant under
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