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Health - Pharmacology - 05.02.2019

Pharmacology - Health - 05.02.2019
Roche submits supplemental biologics license application to the US FDA for Kadcyla for adjuvant treatment of people with HER2-positive early breast cancer with residual disease after neoadjuvant treatment
Roche's application is being reviewed under the US FDA's Real-Time Oncology Review and Assessment Aid pilot programmes Kadcyla was granted Breakthrough Therapy Designation for this application Ro

Pharmacology - Health - 04.02.2019
New steam treatment offers hope for men with an enlarged prostate
A new treatment for enlarged prostates can reduce side effects and has the potential to improve the lives of thousands of men, says an Imperial expert The treatment, which uses steam, has been shown to shrink prostates by 36 per cent and has fewer side effects than current methods.

Pharmacology - Environment - 04.02.2019
£45m to train the next generation of global problem solvers
The University of Nottingham has won new funding for five centres that will train the brightest postgraduate researchers to tackle pressing global challenges, and keep the UK at the cutting edge of scientific research.

Chemistry - Pharmacology - 01.02.2019
First-of-its-kind automatic chemistry facility opens at Imperial
The Centre for Rapid Online Analysis of Reactions (ROAR) is the first national centre for the study of reactions, focusing on data-centric chemistry. ROAR is the flagship Research Facility for the Dial-a-Molecule Grand Challenge , which aims to make the synthesis of any desired molecule ‘as easy as dialling a number'.

Pharmacology - Health - 01.02.2019
CHMP recommends EU approval of Roche’s Tecentriq in combination with Avastin and chemotherapy as an initial treatment for lung cancer
Recommendation based on the Phase III IMpower150 study which showed that Tecentriq (atezolizumab) in combination with Avastin (bevacizumab) and chemotherapy (paclitaxel and carboplatin) helped people

Pharmacology - Health - 01.02.2019
CHMP recommends EU approval of Roche’s Hemlibra for people with severe haemophilia A without factor VIII inhibitors
First medicine to significantly reduce treated bleeds compared to prior factor VIII prophylaxis in a prospective intra-patient comparison First new class of medicine in nearly 20 years for people wit

Health - Pharmacology - 31.01.2019
£10 million gift to drive breakthrough new treatments for myeloma
Imperial College London will establish a new centre for myeloma research at Hammersmith Hospital, thanks to a £10 million donation.

Health - Pharmacology - 30.01.2019
New program offers overlooked treatment for addiction
A patient arrives at the hospital with a raging fever and chills radiating throughout his entire body.

Health - Pharmacology - 30.01.2019
Better out-of-hours palliative care needed
A better understanding of risks and causes of harm for out of hours palliative care is urgently needed to ensure patient safety, finds a study carried out by researchers at Cardiff University.

Pharmacology - Health - 30.01.2019
Roche to discontinue Phase III CREAD 1 and 2 clinical studies of crenezumab in early Alzheimer’s disease (AD) - other company programmes in AD continue
At three years, 88.3% of people treated with Kadcyla in the adjuvant HER2-positive early breast cancer setting did not have their breast cancer return compared to 77.0% treated with Her

Chemistry - Pharmacology - 28.01.2019
How do mRNAs deal with stress?
Two hallmarks of the integrated stress response of cells are the inhibition of translation and the formation of stress granules (SGs) and processing bodies (PBs). However, it is not well understood how both processes are coupled. In a study published in Molecular Cell, researchers from the Chao group applied single-molecule RNA imaging to study the interactions of mRNAs with SGs and PBs, and found out that the generally accepted assumptions about the function of granules need to be revised.

Health - Pharmacology - 23.01.2019
New name for UofG’s world-changing parasitology research centre
The College of MVLS's Wellcome Centre for Molecular Parasitology has had a name change to better reflect its current world-changing research expertise.

Pharmacology - 22.01.2019
Ers warn online GP consultations need careful implementation
The new NHS 10-year plan launched earlier this month [7 January] states all patients in England will have access to a "digital first primary care offer", such as GP online consultations, by 2022/23.

Pharmacology - Life Sciences - 22.01.2019

Health - Pharmacology - 22.01.2019
Design teams shift their focus to developing recommendations to implement Stanford's vision for the future
Design teams shift their focus to developing recommendations to implement Stanford’s vision for the future
To foster community engagement, the university will create a vision to transform the White Plaza area into a vibrant town center.

Pharmacology - Health - 17.01.2019
FDA accepts Roche’s supplemental biologics license application for Tecentriq plus chemotherapy (Abraxane and carboplatin) for the initial treatment of metastatic non-squamous non-small cell lung cancer
Roche today announced that the US Food and Drug Administration (FDA) has accepted the company's supplemental Biologics License Application (sBLA) for Tecentriq (atezolizumab) in combination with Abra

Health - Pharmacology - 16.01.2019
Personalised treatments for Parkinson’s disease
Scientists at Cardiff University are helping to bring personalised treatments for Parkinson's disease closer to the clinic, thanks to a major investment of over £50,000 from American charity, The Summit for Stem Cell Foundation.

Pharmacology - Health - 16.01.2019

Health - Pharmacology - 09.01.2019
Drug sponge could minimize side effects of cancer treatment
Drug sponge could minimize side effects of cancer treatment
With the help of sponges inserted in the bloodstream to absorb excess drugs, doctors are hoping to prevent the dangerous side effects of toxic chemotherapy agents or even deliver higher doses to knock back tumors, like liver cancer, that don't respond to more benign treatments. The "drug sponge" is an absorbent polymer coating a cylinder that is 3D printed to fit precisely in a vein that carries the blood flowing out of the target organ - the liver in liver cancer, for example.

Life Sciences - Pharmacology - 09.01.2019

Health - Pharmacology - 08.01.2019
Novartis investigational therapy crizanlizumab (SEG101) receives FDA Breakthrough Therapy designation for the prevention of vaso-occlusive crises in sickle cell disease
Crizanlizumab is a monthly infusion under development to prevent pain crises (also called vaso-occlusive crises, or VOCs) in patients with sickle cell disease   Sickle cell VOCs, which are triggered

Pharmacology - Health - 07.01.2019
Sandoz and Pear Therapeutics Announce US Launch of reSET-OTM to Help Treat Opioid Use Disorder
ReSET-O(TM)* is the first US FDA-cleared prescription digital therapeutic for patients with Opioid Use Disorder Cleared by the FDA in December, reSET-O is available immediately As part of a broader f

Health - Pharmacology - 21.12.2018
Novartis receives European Commission (EC) approval for expanded indication for Kisqali (ribociclib)
Basel, December 21, 2018 - Novartis today announced that the European Commission (EC) approved an expanded indication for Kisqali  (ribociclib), the CDK4/6 inhibitor with the largest body of first-li

Pharmacology - Health - 20.12.2018
Novartis announces offer to acquire CellforCure to expand manufacturing capacity for innovative cell and gene therapies
Proposed acquisition builds on existing agreement with CellforCure for contract manufacturing of Novartis leading CAR-T cell therapy Kymriah (tisagenlecleucel) and recent successful completion of tec

Pharmacology - 20.12.2018
Molecule predicts patient's ability to survive melanoma
Molecule predicts patient’s ability to survive melanoma
Doctors may be able to assess the survival rates of melanoma patients following the discovery of a molecule that allows the cancer to spread from the skin to other parts of the body.

Business / Economics - Pharmacology - 20.12.2018

Health - Pharmacology - 20.12.2018
Suboptimal, inconsistent treatment for anaphylaxis due to unknown cause
A new Canadian study, led by a team at the Research Institute of the McGill University Health Centre (RI-MUHC), is shedding light on anaphylaxis due to an unknown trigger (AUT)-an unpredictable and potentially fatal allergic reaction, about which surprisingly little is known.

Health - Pharmacology - 17.12.2018
PRIME designation granted by European Medicines Agency for Roche’s risdiplam for treatment of spinal muscular atrophy (SMA)
PRIME designation granted by European Medicines Agency for Roche's risdiplam for treatment of spinal muscular atrophy (SMA) Risdiplam has the potential to be the first oral medicine for the treatment

Health - Pharmacology - 13.12.2018
Adaptive Phage Therapeutics to collaborate with Yale’s Paul Turner Lab
Adaptive Phage Therapeutics Enters into Collaboration Agreement with Researchers at Yale University to Manufacture and Supply Therapeutic Bacteriophage View this release on BusinessWire   Gaithersbur

Health - Pharmacology - 13.12.2018
Novartis receives European Commission approval for self-administration of Xolair across all indications
The EC approval underscores the long-term safety and efficacy of Xolair demonstrated in clinical studies and by 13 years of real-world use in Europe   Xolair (omalizumab) prefilled syringe (PFS) is t

Health - Pharmacology - 12.12.2018
The ABCs of the HPV vaccine
If someone told you there was a vaccine that could prevent most cases of cervical cancer-and a growing number of head and neck cancers-would you get it?

Pharmacology - Health - 12.12.2018
Alzheimer’s drug may help battle antibiotic resistance
Dangerous antibiotic-resistant bacteria could soon be targeted with a drug initially developed to treat Alzheimer's disease.

Pharmacology - Health - 10.12.2018
Sandoz Inc. and Pear Therapeutics Obtain FDA Clearance for reSET-O(TM) to Treat Opioid Use Disorder
ReSET-O TM is the first FDA-cleared Prescription Digital Therapeutic (PDT) for patients with Opioid Use Disorder Pear Therapeutics is leading the development of a new therapeutic class with two FDA-a

Health - Pharmacology - 10.12.2018
Ucla
University News Rev. James Lawson Jr., civil rights icon, champion of nonviolence, receives UCLA Medal Arts + Culture Historian helps create archive at UCLA of South African propaganda comics from th

Health - Pharmacology - 08.12.2018
Novartis data demonstrates consistent efficacy and tolerability of Kisqali combination therapy in HR+/HER2- advanced breast cancer in patients with difficult-to-treat visceral disease
  Subgroup analyses of three pivotal Phase III MONALEESA trials showed Kisqali plus endocrine therapy extended PFS in all patients with and without visceral involvement compared to endocrine therapy

Life Sciences - Pharmacology - 07.12.2018
Dandelion rubber gets ready for the market
Dandelion rubber gets ready for the market
Research done by Prof. Dirk Prüfer and his team makes transfer possible / "Taraxagum project is an outstanding example of the way that Münster University stands for top-level research" Years ago, the idea sounded anything from weird to audacious: manufacturing car tyres from dandelions.

Pharmacology - Health - 07.12.2018
FDA approves Roche’s Tecentriq in combination with Avastin and chemotherapy for the initial treatment of people with a specific type of metastatic lung cancer
Approval based on survival benefit of Tecentriq in combination with Avastin, paclitaxel and carboplatin (chemotherapy) in people with metastatic non-squamous non-small cell lung cancer (NSCLC) with n

Astronomy / Space Science - Pharmacology - 06.12.2018
Blast off for first UK-led experiment on the International Space Station
UK-led research is taking place on the International Space Station (ISS) for the first time, following a successful launch from Kennedy Space Centre at Cape Canaveral in the US. An experiment using microscopic nematode worms involving teams of scientists from the Universities of Nottingham, Exeter and Lancaster was among a shipment of cargo and scientific investigations to be delivered to the ISS by the SpaceX Dragon spacecraft following the launch by the SpaceX Falcon 9 rocket at 6.16 pm (UK time) on Wednesday 5 December.

Health - Pharmacology - 05.12.2018
Roche’s Kadcyla cut the risk of disease recurring by half compared to Herceptin in people with HER2-positive early breast cancer with residual disease after neoadjuvant treatment
At three years, 88.3% of people treated with Kadcyla in the adjuvant HER2-positive early breast cancer setting did not have their breast cancer return compared to 77.0% treated with Her

Life Sciences - Pharmacology - 05.12.2018
CMU Welcomes New Head of Chemical Engineering
Internationally renowned researcher Anne Skaja Robinson has joined Carnegie Mellon University as head of its Department of Chemical Engineering.

Pharmacology - Health - 05.12.2018
FDA grants priority review to Roche’s Tecentriq in combination with chemotherapy for the initial treatment of extensive-stage small cell lung cancer
Roche today announced that the US Food and Drug Administration (FDA) has accepted the company's supplemental Biologics License Application (sBLA) and granted Priority Review for Tecentriq (atezolizum

Pharmacology - Health - 04.12.2018
Novartis advances ligelizumab (QGE031) in urticaria to Phase III on basis of strong Phase II head-to-head data
PEARL 1 and PEARL 2, the largest pivotal trials to date in chronic spontaneous urticaria (CSU), will enroll more than 2,000 CSU patients ,   Ligelizumab (QGE031), a monoclonal antibody, is being deve

Pharmacology - Health - 04.12.2018
New Venclexta/Venclyxto data demonstrate deep responses in two of the most common types of leukaemia
New analyses from the phase III MURANO study in previously treated chronic lymphocytic leukaemia show continued benefit from fixed-duration regimen after a median follow-up of three years Updated res

Pharmacology - Health - 03.12.2018
Roche’s Hemlibra provided sustained bleed control in the largest pivotal study to date of children with haemophilia A with factor VIII inhibitors
Nearly 77% of children receiving Hemlibra once weekly experienced zero treated bleeds Hemlibra once weekly reduced treated bleeds by 99% compared to prior bypassing agents in a prospective intra-pati