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Pharmacology - Health - 19.03.2019
FDA approves Roche’s Tecentriq in combination with chemotherapy for the initial treatment of adults with extensive-stage small cell lung cancer
Tecentriq in combination with chemotherapy (carboplatin and etoposide) is the first and only cancer immunotherapy approved for the initial treatment of extensive-stage small cell lung cancer (ES-SCLC

Health - Pharmacology - 15.03.2019
Researchers offered 'quick and easy' grants to get medical innovations started
Researchers offered ’quick and easy’ grants to get medical innovations started
A scheme is offering grants to help researchers test ideas for translating their research into new drugs, diagnostics or medical devices.

Pharmacology - Health - 15.03.2019
European Commission approves Roche’s MabThera (rituximab) for a rare autoimmune disease
MabThera is the first biologic treatment approved for moderate to severe cases of the rare autoimmune disease pemphigus vulgaris (PV), and the first major advancement in the treatment of the disease

Health - Pharmacology - 14.03.2019
Novartis joins the Global Chagas Disease Coalition and also announces first multinational, prospective, randomized study in people with chronic Chagas cardiomyopathy
Study is planned to assess efficacy and safety of Entresto (sacubitril / valsartan) vs enalapril in 900 patients with chronic Chagas cardiomyopathy; recruitment is planned to commence within 2019   C

Pharmacology - 14.03.2019
Drug use in Swiss cities unchanged
Drug use in Swiss cities unchanged
In a large-scale, Europe-wide drug monitoring project, the wastewater of around 38 million people in 85 cities was analysed in the spring.

Pharmacology - Health - 14.03.2019
European Commission approves Roche’s Hemlibra for people with severe haemophilia A without factor VIII inhibitors
First medicine to significantly reduce treated bleeds compared to prior factor VIII prophylaxis, in a prospective intra-patient comparison Only prophylactic medicine that can be given subcutaneously

Pharmacology - Business / Economics - 13.03.2019

Health - Pharmacology - 13.03.2019
Reducing the burden of tuberculosis treatment
Reducing the burden of tuberculosis treatment
Drug delivery system would allow patients to switch from daily to monthly doses. One-third of the world's population is infected with TB, and more than 1 million people die from the disease every year.

Health - Pharmacology - 12.03.2019
Evidence-based web tool aims to better inform and refine need for treatment in early prostate cancer
A new tool to predict an individual's prognosis following a prostate cancer diagnosis could help prevent unnecessary treatment and related side effects, say researchers at the University of Cambridge. We believe this tool could significantly reduce the number of unnecessary - and potentially harmful - treatments that patients receive and save the NHS millions every year Vincent Gnanapragasam The tool, PREDICT Prostate, launches today to coincide with publication in the journal PLOS Medicine of the research that underpins it.

Health - Pharmacology - 11.03.2019
FDA grants Roche’s Tecentriq in combination with Abraxane accelerated approval for people with PD-L1-positive, metastatic triple-negative breast cancer
This Tecentriq combination is the first cancer immunotherapy regimen approved for breast cancer Triple-negative breast cancer is an aggressive disease, with high unmet medical need Roche today announ

Health - Pharmacology - 11.03.2019
Roche’s VENTANA PD-L1 (SP142) Assay approved as first companion diagnostic to identify triple-negative breast cancer patients eligible for treatment with Tecentriq in combination with Abraxane
PD-L1 (SP142) was the enrollment assay used in the IMpassion130 trial, the first positive phase III immunotherapy regimen study in triple-negative breast cancer Each year about 300,000 women are diag

Pharmacology - Life Sciences - 08.03.2019
Safer brains and mechanical hearts: News from the College
Safer brains and mechanical hearts: News from the College
Here's a batch of fresh news and announcements from across Imperial. From better materials for crash helmets, to a bioreactor which mimics heartbeats, here is some quick-read news from across the College.

Pharmacology - Health - 08.03.2019
European Commission approves Roche’s Tecentriq in combination with Avastin and chemotherapy for the initial treatment of people with a specific type of metastatic lung cancer
Approval based on significant survival benefit of Tecentriq in combination with Avastin, paclitaxel and carboplatin (chemotherapy) in people with metastatic non-squamous non-small cell lung cancer (N

Health - Pharmacology - 07.03.2019
Roche commences tender offer for all shares of Spark Therapeutics, Inc. for US$ 114.50 per share in cash
Roche commences tender offer for all shares of Spark Therapeutics, Inc. for US$ 114.50 per share in cash Roche today announced that it has commenced a cash tender offer for all of the outstanding shares of common stock of Spark Therapeutics, Inc.

Pharmacology - Health - 07.03.2019
Roche submits supplemental new drug application to FDA for Venclexta plus Gazyva for previously untreated chronic lymphocytic leukaemia with co-existing medical conditions
Application is being reviewed under FDA's Real-Time Oncology Review pilot programme Combination was granted Breakthrough Therapy Designation, the fifth for Venclexta Roche today announced the submiss

Health - Pharmacology - 05.03.2019
HRH The Duke of Sussex visits the world’s first conflict wound research centre
HRH The Duke of Sussex met scientists and clinical experts from the University of Birmingham and University Hospitals Birmingham NHS Foundation Trust during a visit to the world's first specialist military and civilian wound research centre.

Health - Pharmacology - 05.03.2019
Novartis Cosentyx shows superior improvements in psoriasis patients’ quality of life versus Janssen’s IL-23 Stelara *
New CLARITY data show over two-thirds of Cosentyx (secukinumab) treated patients with moderate to severe psoriasis reported no impact of skin disease on their quality of life (QoL) up to Week 16 compared to Stelara * (68.4% versus 55.9%, respectively)   Results from CLARITY study presented in 2018 showed Cosentyx was significantly more effective than Stelara * in delivering clear and almost clear skin at 12 and 16 weeks.

Health - Pharmacology - 01.03.2019
Funding awarded to advance treatment of skeletal disorders in children
University of Birmingham Professor Grant Stewart has received £246,993 from Great Ormond Street Hospital Children's Charity and children's medical research charity Sparks to fund research into the ad

Health - Pharmacology - 28.02.2019
FDA approves Herceptin Hylecta for subcutaneous injection in certain HER2-positive breast cancers
Roche today announced that the US Food and Drug Administration (FDA) has approved Herceptin Hylecta? (trastuzumab and hyaluronidase-oysk) for subcutaneous (under the skin) injection for the treatment

Health - Pharmacology - 28.02.2019
Oxford-Harrington Rare Disease Centre to research rare diseases therapies
The University of Oxford and Harrington Discovery Institute at University Hospitals have announced a new affiliation to advance therapies for rare diseases.

Pharmacology - Health - 27.02.2019
Yeast produce low-cost, high-quality cannabinoids
UC Berkeley synthetic biologists have engineered brewer's yeast to produce marijuana's main ingredients-mind-altering THC and non-psychoactive CBD-as well as novel cannabinoids not found in the plant itself.

Pharmacology - Health - 27.02.2019

Health - Pharmacology - 25.02.2019
Roche enters into definitive merger agreement to acquire Spark Therapeutics
Roche to acquire Spark Therapeutics for US$ 114.50 per share Spark Therapeutics is a leader in discovering, developing and delivering gene therapies with one commercial asset and four programm

Pharmacology - Health - 19.02.2019
FDA grants priority review to Roche’s polatuzumab vedotin in previously treated aggressive lymphoma
Diffuse large B-cell lymphoma is an aggressive type of blood cancer that typically becomes harder to treat each time it returns Polatuzumab vedotin has shown significant potential to improve outcomes

Health - Pharmacology - 19.02.2019
FDA grants Priority Review to Roche’s personalised medicine entrectinib
Roche today announced that the US Food and Drug Administration (FDA) has accepted the company's New Drug Applications (NDAs) and granted Priority Review for entrectinib for the treatment of adult and

Pharmacology - 18.02.2019
Testing pain relief treatments for whiplash
Testing pain relief treatments for whiplash
Researchers are investigating the effectiveness of non-opioid pain relief for people with acute whiplash.

Pharmacology - 15.02.2019
7,000 strokes per year prevented as GPs improve diagnosis and treatment of atrial fibrillation
Around 7,000 strokes each year are being prevented thanks to GPs more than doubling the number of patients at high risk being prescribed with drugs to prevent blood clotting, University of Birmingham researchers have found. Researchers from the University of Birmingham's Institute for Applied Health Research analysed general practice records of five million patients from 2000 to 2016 to find out how many people have a diagnosis of atrial fibrillation and how many are receiving treatment to prevent strokes.

Health - Pharmacology - 13.02.2019
Novartis receives FDA approval for Egaten for the treatment of fascioliasis, a neglected tropical disease
Egaten is the only drug approved in the US for the treatment of people with fascioliasis and is currently the only treatment recommended by the WHO   Fascioliasis, commonly known as liver fluke infes

Pharmacology - Business / Economics - 13.02.2019
Redesigning pharmacies with the consumer in mind
Redesigning pharmacies with the consumer in mind
Alto Pharmacy uses software and an innovative operations model to improve access to medication. Getting medication to a patient requires coordination between the doctor who writes the prescription, the insurance company that provides coverage, and the pharmacy that ultimately hands over the drug.

Health - Pharmacology - 12.02.2019
£1.5m funding boost for UofG diagnostics spinout
A University of Glasgow spinout which is bringing to market a fast, affordable and efficient new way to diagnose diseases has received a major funding boost.

Pharmacology - 12.02.2019
GPs and pharmacists don’t have time to involve patients in medication reviews
GPs and pharmacists struggle to find the time to involve patients in medication reviews, despite National Institute for Health and Care Excellence (NICE) guidance advising them to do so, according to a study by researchers at the University of Bristol's Centre for Academic Primary Care.

Health - Pharmacology - 11.02.2019
New children's research facility opens at Imperial
New children’s research facility opens at Imperial
A research facility that aims to improve the quality of life, treatment and care for children with complex diseases formally opened this month.

Health - Pharmacology - 07.02.2019
In seminar, Tom Lynch talks drug development and improving patient outcomes
New Haven, CT -   Dr. Tom Lynch, former Director of Yale Cancer Center and current Chief Scientific Officer at Bristol-Myers Squibb, returned to campus Wednesday to deliver a talk on 'Cancer Drug Discovery: Role of the University/Hospital, Biotech and Pharma to Improve Patient Outcomes.

Pharmacology - Health - 07.02.2019
Teaching the immune system to fight cancer
Editor's note: This piece was adapted from a story that originally appeared in the  University of Chicago Magazine.

Life Sciences - Pharmacology - 07.02.2019
This is a Neuron on Nicotine
This is a Neuron on Nicotine
When a person takes a puff on a cigarette, nicotine floods into the brain, latching onto receptors on the surface of neurons and producing feelings of happiness.

Health - Pharmacology - 05.02.2019

Pharmacology - Health - 05.02.2019
Roche submits supplemental biologics license application to the US FDA for Kadcyla for adjuvant treatment of people with HER2-positive early breast cancer with residual disease after neoadjuvant treatment
Roche's application is being reviewed under the US FDA's Real-Time Oncology Review and Assessment Aid pilot programmes Kadcyla was granted Breakthrough Therapy Designation for this application Ro

Pharmacology - Health - 04.02.2019
New steam treatment offers hope for men with an enlarged prostate
A new treatment for enlarged prostates can reduce side effects and has the potential to improve the lives of thousands of men, says an Imperial expert The treatment, which uses steam, has been shown to shrink prostates by 36 per cent and has fewer side effects than current methods.

Pharmacology - Environment - 04.02.2019
£45m to train the next generation of global problem solvers
The University of Nottingham has won new funding for five centres that will train the brightest postgraduate researchers to tackle pressing global challenges, and keep the UK at the cutting edge of scientific research.

Chemistry - Pharmacology - 01.02.2019
First-of-its-kind automatic chemistry facility opens at Imperial
The Centre for Rapid Online Analysis of Reactions (ROAR) is the first national centre for the study of reactions, focusing on data-centric chemistry. ROAR is the flagship Research Facility for the Dial-a-Molecule Grand Challenge , which aims to make the synthesis of any desired molecule ‘as easy as dialling a number'.

Pharmacology - Health - 01.02.2019
CHMP recommends EU approval of Roche’s Tecentriq in combination with Avastin and chemotherapy as an initial treatment for lung cancer
Recommendation based on the Phase III IMpower150 study which showed that Tecentriq (atezolizumab) in combination with Avastin (bevacizumab) and chemotherapy (paclitaxel and carboplatin) helped people

Pharmacology - Health - 01.02.2019
CHMP recommends EU approval of Roche’s Hemlibra for people with severe haemophilia A without factor VIII inhibitors
First medicine to significantly reduce treated bleeds compared to prior factor VIII prophylaxis in a prospective intra-patient comparison First new class of medicine in nearly 20 years for people wit

Health - Pharmacology - 31.01.2019
£10 million gift to drive breakthrough new treatments for myeloma
Imperial College London will establish a new centre for myeloma research at Hammersmith Hospital, thanks to a £10 million donation.

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