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EPFL scientists have discovered how low-dose anxiolytics increase the social competitiveness of high-anxious individuals by boosting the energy output of mitochondria in an area of the mammalian brain that controls motivation and reward. Psychologists speak of anxiety in two forms: 'state' anxiety, which refers to anxiety arising from a particular situation; and 'trait' anxiety, which refers to anxiety as part of a person's overall personality. Studies have shown that high trait anxiety can seriously hamper a person's ability to compete in a social context, thus putting 'highly anxious' individuals in a circle of social disadvantage and more anxiety. Now EPFL scientists have shown that low doses of anxiolytic drugs - such as diazepam (Valium) - can ameliorate this effect by increasing the activity of mitochondria in the neurons of a brain pathway associated with motivation and reward. The work is published in Molecular Psychiatry . Anxiety and anxiolytics Some people tend to be relaxed while others are perpetually worried and tense. The difference is what psychologists call 'trait anxiety', and studies have shown that can have significant consequences on social life.
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