Yale University

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Health - Life Sciences - 01.07.2024
Kids’ susceptibility to seasonal viruses may protect them from COVID-19
A new study finds that frequent viral and bacterial infections in children boost nasal immune defenses, which may have helped protect kids from severe COVID-19. Any parent of young children can tell you kids are more susceptible to common colds than adults. But a new study suggests that susceptibility to a variety of respiratory infections may be part of what protected children from severe COVID-19.

Health - Pharmacology - 25.06.2024
Boosting ’natural killer’ cell activity could improve cancer therapy
Natural killer cells hold promise for treating cancer. Yale researchers have found a way to overcome their main limitation. Yale researchers have uncovered a way to make a type of white blood cells known as natural killer cells - which kill infected, damaged, or malignant cells in the body - more effective against cancer.

Health - Life Sciences - 20.06.2024
New enzyme developed at Yale offers hope for patients with lupus
An enzyme engineered by Yale researchers prevented lupus in mice and shows promise for patients with the disease. An enzyme-based treatment developed by Yale researchers mitigated autoimmunity and reduced death rates in both genetic and non-genetic mouse lupus models, a new study reveals. The findings, which were published June 17 in the journal JCI Insight , represent a significant advancement in autoimmune disease therapeutics, said the researchers.

Life Sciences - Mathematics - 13.06.2024
New insights into the brain regions involved in paranoia
New insights into the brain regions involved in paranoia
Through a novel approach, Yale researchers translate data from monkeys to better understand how paranoia arises in the human brain. The capacity to adjust beliefs about one's actions and their consequences in a constantly changing environment is a defining characteristic of advanced cognition. Disruptions to this ability, however, can negatively affect cognition and behavior, leading to such states of mind as paranoia, or the belief that others intend to harm us.

Social Sciences - Politics - 04.06.2024
'Fuzzy' maps offer insight into local perceptions of volunteering's value
’Fuzzy’ maps offer insight into local perceptions of volunteering’s value
In a new study, Yale researchers employed fuzzy cognitive mapping to better understand how volunteering benefits poor women in Jordan. In the global South, volunteer programs are framed by policymakers and scholars as an effective vehicle for empowering women living in poverty. But this narrative often rests on scant knowledge of the perspectives and experiences of a key set of local stakeholders: the volunteers.

Health - 29.05.2024
To avoid infection spread, how long a quarantine is sufficient? It depends
To avoid infection spread, how long a quarantine is sufficient? It depends
Yale researchers assessed how long international travelers should be quarantined to prevent COVID-19 infection rise, finding it differed quite a bit by country. In December 2022, China lifted the stringent COVID-19 restrictions it had imposed early in the pandemic, and infections throughout the country rapidly increased.

Health - Life Sciences - 24.05.2024
Physical frailty may put people at greater risk of depression
The findings of a new Yale study suggest physical frailty may be a risk factor for depression - and a target for intervention. Individuals who meet at least one of the criteria for physical frailty are at higher risk of also developing depression, a new Yale study finds. The findings - which also include insights into the specific inflammatory molecules and changes in brain structure that could underlie this association between frailty and depression - point to a need for routine assessment of physical frailty in clinical practice, researchers said.

Health - Pharmacology - 24.05.2024
In stroke response, speed is key; Yale study reveals where delays are worst
In stroke response, speed is key; Yale study reveals where delays are worst
When it comes to stroke treatment, every minute counts. A new study identifies factors associated with treatment delays - and targets for intervention. When it comes to responding to a stroke, speed is a crucial factor; the longer it takes for someone experiencing a stroke to get to a hospital, the worse the outcome will be.

Health - Life Sciences - 23.05.2024
Sea of love: Behind the unusual sexual parasitism of deep-water anglerfish
Sea of love: Behind the unusual sexual parasitism of deep-water anglerfish
A new study illuminates the evolution of deep-sea anglerfish with a focus on the development of their unique (and somewhat unsettling) mating routine. As the planet's most expansive ecosystem, the deep sea can be a tough place to find a mate. Though, scientists say, some deep-sea anglerfishes evolved a unique method of reproduction that ensures that once they land a partner in the vast open waters, they remain latched for life.

Life Sciences - Health - 23.05.2024
Tracking the cellular and genetic roots of neuropsychiatric disease
Tracking the cellular and genetic roots of neuropsychiatric disease
A new study of nearly 400 human brains links genetic variants to genes and cell types, which could help enable precision-medicine for neuropsychiatric disease. A new analysis has revealed detailed information about genetic variation in brain cells that could open new avenues for the targeted treatment of diseases such as schizophrenia and Alzheimer's disease.

Chemistry - Environment - 17.05.2024
Sun, sustainability, and silicon: A double dose of Yale solar fuel research
Sun, sustainability, and silicon: A double dose of Yale solar fuel research
Two Yale-led studies indicate the promise of finding hybrid approaches to developing alternative solar fuels. The CHASE is on to develop a new generation of liquid fuels that are activated by sunlight, and Yale researchers are helping to lead the way. Over the past decade, basic research aimed at creating sustainable, solar-powered liquid fuel has reached a crossroads.

Life Sciences - 13.05.2024
What makes a memory? It may be related to how hard your brain had to work
A computational model and behavioral study developed by Yale scientists gives a new clue to the age-old question of how our brain prioritizes what to remember. The human brain filters through a flood of experiences to create specific memories. Why do some of the experiences in this deluge of sensory information become "memorable," while most are discarded by the brain' A computational model and behavioral study developed by Yale scientists suggests a new clue to this age-old question, they report in the journal Nature Human Behavior .

Astronomy / Space - Physics - 09.05.2024
The search is on for signs of the first stars in the universe
Yale's Priyamvada Natarajan and colleagues say the first stars left behind distinctive flares that can be detected by a new generation of space telescopes. Astronomers at Yale and the University of Hong Kong have proposed a new strategy for finding the universe's first stars - by looking for signs of their final, fiery flares.

Health - Life Sciences - 08.05.2024
Getting to know the enzymes behind cell communication - and tumor growth
In the body, certain enzymes are key to cell communication and their dysfunction can lead to cancer. A new study begins to uncover how they signal and when. In the human body, molecules known as kinases propagate signals within and between cells, relaying signals that allow cells to respond to changes in the environment.

Health - 06.05.2024
Brain activity related to craving and heavy drinking differs across sexes
Brain activity related to alcohol craving and future heavy drinking is different across sexes, a new study finds, which could have implications for treatment. The brain circuits that underlie alcohol craving and heavy drinking share some similarities between men and women, but also some key differences, a new Yale study reveals.

Psychology - Health - 03.05.2024
Rapid emotion transitions may explain numbness and hyperreactivity in PTSD
Patients with PTSD experience both emotional numbness and hyperreactivity. A new study digs into how these contrasting symptoms are linked. Patients diagnosed with posttraumatic stress disorder (PTSD) can experience symptoms that include under-expression of emotions, such as numbness, as well as over-expression, such as rage outbursts.

Health - Social Sciences - 02.05.2024
Targeting friends to induce social contagion to benefit the world
In a new study, researchers induced social contagion in Honduran villages by targeting people's friends to receive a health intervention. A new study co-authored by Yale sociologist Nicholas A. Christakis demonstrates that tapping into the dynamics of friendship significantly improves the possibility that a community will adopt public health and other interventions aimed at improved human wellbeing.

Health - 30.04.2024
Understanding youth nicotine use to prevent initiation and escalation
In a new study, Yale researchers uncover factors that are associated with multiple nicotine product use in adolescents. Using multiple nicotine products can be associated with higher levels of nicotine dependence among youth and increased mortality in adults, compared with the use of one product alone.

Health - Life Sciences - 25.04.2024
Study identifies driver of liver cancer that could be target for treatment
Inhibiting a certain protein in mice reduced obesity-induced liver tumor development, Yale researchers found. It could reveal a future treatment route. Metabolic diseases like obesity can increase the risk of developing liver cancer, research has shown. But how one disease predisposes to the other is unclear.

Health - Pharmacology - 22.04.2024
Common antibiotic may be helpful in fighting respiratory viral infections
Yale researchers say that nasal application of neomycin shows promise in the prevention and treatment of respiratory viral infections A new, Yale-led study suggests that a range of respiratory viral infections - including COVID-19 and influenza - may be preventable or treatable with a generic antibiotic that is delivered to the nasal passageway.
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