A new approach to tackling viruses by targeting the 'control centre' in viral RNA could lead to broad spectrum anti-viral drugs and provide a first line of defence against future pandemics, according to new research at the University of Birmingham.
Scientists have used a novel algorithmic approach on cancer cells to understand how changes in histone marks (H3K27ac) induce repositioning of chromatin regions in the cell nucleus, and described how modifications of local contacts between regulatory elements (enhancers and promoters) influence oncogene expression.
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UCLA scientists have identified a molecular switch that prevents Huntington's disease from developing in mice. Published in the Dec. 24 edition of the journal Neuron, the discovery suggests a new approach to treating the genetic disorder, which ultimately leads to death in as little as 10 years. Affecting one out of every 10,000 Americans, Huntington's progressively deprives patients of their ability to walk, speak, think clearly and swallow.
The link between obesity and mortality from cardiovascular disease, diabetes and certain forms of cancer may be substantially underestimated, according to a new study from Karolinska Institutet. The study, which is published in the scientific journal BMJ, also suggests that some of the adverse consequences of being underweight may be overstated.
BERKELEY — Nearly 10 years after the discovery that birds make a hormone that suppresses reproduction, University of California, Berkeley, neuroscientists have established that humans make it too, opening the door to the development of a new class of contraceptive and possible treatments for cancer or other diseases.
Michael Browne, Head of European Research and Development at UCL said: ?These grants are designed to allow exceptional established research leaders in any field of science, engineering and scholarship to pursue risk-taking, interdisciplinary and pioneering research. The Advanced Grant scheme, in particular, is highly competitive (with an overall success rate of seven percent) and highly prestigious.? MECHANICITY (Morphology, Energy and Climate cHANge In the CITY) led by Professor Michael Batty (UCL Centre for Advanced Spatial Analysis).
As the Beatles Rock Band and Wii Fit top the Christmas charts, new research from the University of Birmingham reveals that social interactions are key to designing a hit video game. Findings suggest the most important elements of good game design include variety, cohesion, a good social aspect and good user interaction, while bad pricing should be avoided.
The national research network Swedish Brain Power, which is led and coordinated from Karolinska Institutet, is to receive SEK 100 million from the Knut and Alice Wallenberg Foundation. Its research focuses on early diagnosis and treatment and improved care for patients with Alzheimer's disease, Parkinson's disease and ALS.
The University of Plymouth's world-leading ocean acidification research has been highlighted in a United Nations report launched at the end of the Copenhagen Climate Change summit. 'Scientific Synthesis of the Impacts of Ocean Acidification on Marine Biodiversity', compiled by the Secretariat of the Convention on Biological Diversity is the most comprehensive overview to date of all existing scientific evidence on ocean acidification - including breakthrough research led by the University of Plymouth’s Jason Hall-Spencer.
Astronomers have discovered the second super-Earth exoplanet for which they have determined the mass and radius, giving vital clues about its structure.
Tissue-specific genes, long thought to be dormant or unmarked for activation in embryonic stem cells, are indeed marked by transcription factors, and this marking may be crucial for the function of tissues derived from stem cells, UCLA Broad Stem Cell Center researchers have discovered. The findings, published in the Dec.
A variant of the gene encoding the MMP12 protein is associated with increased lung function in children with asthma and in adult smokers. It is also associated with a decreased risk of chronic obstructive pulmonary disease (COPD) by 35 percent in adult smokers, according to an international study published in New England Journal of Medicine.
The discovery, reported in the journal's Oct. 2 issue by an international team co-led by Tim White, a University of California, Berkeley, professor of integrative biology, surprised scientists because Ardi doesn't look like a human or our presumed relative, the chimpanzee. Short for Ardipithecus ramidus, Ardi was a female who lived 4.4 million years ago in what is now the Afar region of Ethiopia.
Cambridge, Mass. December 17, 2009 - Scientists at Harvard University have used light and genetic trickery to trace out neurons' ability to excite or inhibit one another, literally shedding new light on the question of how neurons interact with one another in live animals. The work is described in the current issue of the journal Nature Methods.
December 17, 2009 — When bombs and bullets left 37 dead during Friday prayers at a mosque in Pakistan, earlier this month, the insurgency was using the element of surprise. Unpredictability is the hallmark of modern insurgent attacks such as this one. However, the likelihood of such events, their timing and strength can now be estimated and managed before occurring, according to a new study by researchers at the University of Miami.
Analysis of human remains buried in the 1st century 'Tomb of the Shroud? in Jerusalem has revealed evidence of ancient leprosy and tuberculosis. The new research, involving UCL researchers, is published in the journal PLoS One today. This is the first time that a 1st century tomb from Jerusalem has been investigated by molecular methods.
Historically, authorities have used broad media campaigns to encourage the public to prepare for disasters — an approach that has proven largely ineffective. For this new study, UCLA researchers sought to test novel, culturally tailored, informal social networking approaches to improve disaster preparedness, using data on 231 Hispanics in Los Angeles County.
Physically active individuals have an increased sense of accomplishment, or situation-specific self-confidence, which in turn results in reduced depression and reduced fatigue, said Edward McAuley, a professor of kinesiology and community health at Illinois and lead author on the study. Photo by L. Brian Stauffer CHAMPAIGN, lll.
Men who have recently been diagnosed with prostate cancer are at greater risk of committing suicide and developing and dying from cardiovascular disease, reveals a study from Karolinska Institutet published in the open scientific journal PLoS Medicine. "Cardiovascular disease and suicide can be viewed as a manifestation of exceptional psychological stress," says Katja Fall, one of the researchers behind the study.
Not so long ago, our computers had a single core which had to be boosted for performance - making each machine into a great central heating system.
PA321/09 Scientists have discovered five genetic variants that are associated with the health of the human lung. The research by an international consortium of 96 scientists from 63 centres in Europe and Australia sheds new light on the molecular basis of lung diseases. The new findings provide hope for better treatment for lung diseases like Chronic Obstructive Pulmonary Disease (COPD) and asthma.
Independent whether we consider grapevines in the vineyard or tomatoes in the greenhouse: how well plants are being supplied with water can be viewed by an innovative magnetic probe that is simply clamped to the leaves.