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Health - Pharmacology - 29.12.2022
Immune signature discovered for Long Covid
Severe covid 19 disease is characterized by excessive immune and inflammatory processes in the body. Conversely, long covid syndrome is likely to have a strong anti-inflammatory immune status. Scientists have now found this out with extensive blood plasma analyses of vaccinated persons without subsequent disease, persons with completely survived covid 19 infection and long covid patients.

Pharmacology - Health - 23.12.2022
COVID-19 treatments have long-term benefits for patients
Drugs used to treat critically ill COVID-19 patients in hospital have long-term benefits, according to new research. The study, published in JAMA , found that treating critically ill patients with the drugs tocilizumab and sarilumab reduced the risk of dying over six months by a quarter, compared to those who did not receive these treatments.

Health - Pharmacology - 22.12.2022
Trial to explore the use of psychedelics for alcohol use disorder
Trial to explore the use of psychedelics for alcohol use disorder
Researchers at the University of Sydney are embarking on an Australian first research trial into the use of psychedelics in combination with psychotherapy for the treatment of alcohol use disorder. The trial builds on a growing body of innovative research on psychedelic medications for substance use disorders supported by the National Health and Medical Research Council, Medical Research Future Fund and pharmaceutical industry partners.

Health - Pharmacology - 20.12.2022
Antimalarial Drug Proves Ineffective at Saving Children's Lives
Antimalarial Drug Proves Ineffective at Saving Children’s Lives
Rectal artesunate, a promising antimalarial drug, has no beneficial effect on the survival of young children with severe malaria when used as an emergency treatment in resource-constrained settings. These are the results of a large-scale study conducted by the Swiss Tropical and Public Health Institute and local partners in three African countries.

Health - Pharmacology - 20.12.2022
Promising Antimalarial Drug Proves Ineffective at Saving Children's Lives
Promising Antimalarial Drug Proves Ineffective at Saving Children’s Lives
A large-scale study by the Swiss Tropical and Public Health Institute (Swiss TPH) and partners has found that rectal artesunate (RAS) has no beneficial effect on the survival of young children with severe malaria when used as an emergency treatment in resource-constrained settings. The study, which took place under real-world conditions in three African countries, concludes that the use of RAS is unlikely to reduce malaria deaths unless underlying health system weaknesses are addressed.

Health - Pharmacology - 19.12.2022
First-line defences against COVID-19 are short-lived and may explain reinfection
A new study finds that antibodies produced in the nose decline 9 months after infection, while those found in the blood last at least a year. A new study finds that antibodies produced in the nose decline nine months after COVID-19 infection, while antibodies found in the blood last at least a year.

Health - Pharmacology - 19.12.2022
New approach in the battle against malaria
New research by a team of UT researchers could provide a promising approach in the battle against malaria. In the research published in the scientific journal ACS Infectious Diseases , the researchers combat the malaria parasite in mosquitoes in a specific phase of their life. "It's a unique approach: previous research focused predominantly on treatment in humans." Malaria is a major health problem all over the world.

Health - Pharmacology - 19.12.2022
Relationship between high-dose statin therapy and risk of osteoporosis confirmed in mouse models
Using several million medical records, a research group from MedUni Vienna and the Complexity Science Hub (CSH) showed that there was a correlation between the dosage of statins and the diagnosis of osteoporosis as early as 2019. This finding has now been confirmed in a preclinical study, which was recently published in the journal Biomedicine and Pharmacotherapy.

Pharmacology - Health - 19.12.2022
Technique for tracking resistant cancer cells could lead to new treatments for relapsing breast cancer patients
Technique for tracking resistant cancer cells could lead to new treatments for relapsing breast cancer patients
Cambridge scientists have managed to identify and kill those breast cancer cells that evade standard treatments in a study in mice. The approach is a step towards the development of new treatments to prevent relapse in patients. Tumours are incredibly complex, made up of many different types of tumour cells - and some of these cells are able to evade standard cancer treatments Kirsty Sawicka Tumours are complex entities made up of many types of cells, including cancer cells and normal cells.

Life Sciences - Pharmacology - 19.12.2022
How the brain gives rise to cravings: neuromarker sheds new light
How the brain gives rise to cravings: neuromarker sheds new light
Yale researchers have uncovered a pattern of brain activity that predicts drug and food craving, a potentially valuable biomarker for addiction. Craving is known to be a key factor in substance use disorders and can increase the likelihood of future drug use or relapse. Yet its neural basis - or, how the brain gives rise to craving - is not well understood.

Life Sciences - Pharmacology - 19.12.2022
Newly identified neuromarker reveals clues about drug and food craving
Newly identified neuromarker reveals clues about drug and food craving
Yale researchers have uncovered a pattern of brain activity that predicts drug and food craving, a potentially valuable biomarker for addiction. Craving is known to be a key factor in substance use disorders and can increase the likelihood of future drug use or relapse. Yet its neural basis - or, how the brain gives rise to craving - is not well understood.

Health - Pharmacology - 19.12.2022
Global study presents first results on the longer-term effects of therapies for the treatment of critically ill patients with COVID-19
Global study presents first results on the longer-term effects of therapies for the treatment of critically ill patients with COVID-19
Published today in The Journal of the American Medical Association ( JAMA ), the study is part of the ongoing Randomized Embedded Multifactorial Adaptive Platform for Community Acquired Pneumonia (REMAP-CAP) trial and was led by Monash University's Dr Lisa Higgins from the School of Public Health and Preventive Medicine.

Life Sciences - Pharmacology - 16.12.2022
Starvation Causes Cell Remodeling
New study on "starvation response" by Freie Universität professor of pharmacology published in Science / Joint press release with the Leibniz-Forschungsinstitut für Molekulare Pharmakologie Body cells burn off fat reserves when nutrient supply from food ceases. A team led by Professor Volker Haucke and Dr. Wonyul Jang from the Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) has now discovered a previously unknown mechanism for how this "starvation response" is triggered and what can inhibit it.

Life Sciences - Pharmacology - 16.12.2022
When hungry, the cell remodels
When hungry, the cell remodels
Body cells burn fat reserves when the supply of nutrients from food is interrupted. A team led by Volker Haucke of Freie Universität Berlin and the Leibniz Research Institute for Molecular Pharmacology (FMP) and Wonyul Jang of the FMP has now discovered a previously unknown mechanism for how this "starvation metabolism" gets going - and what can inhibit it.

Health - Pharmacology - 16.12.2022
Medical cannabis treating at least 2.7 percent of population
Medical cannabis treating at least 2.7 percent of population
An estimated 600,000 Australians are using medical cannabis - but that's according to data from 2019. Considering the dramatic increase in the number of doctors registering to prescribe in the past two years, and the rapid growth of applications for prescriptions, the figure today is likely to be much higher.

Health - Pharmacology - 16.12.2022
The most common type 2 diabetes drug needs the action of a cellular-stress-response protein to make effect
The most common type 2 diabetes drug needs the action of a cellular-stress-response protein to make effect
Metformin, the most prescribed drug for treating diabetes mellitus, known as type 2 diabetes, requires the presence of the growth differentiation factor 15 (GDF15) —a protein whose expression increases in response to cellular stress— to present its antidiabetic effects.

Health - Pharmacology - 15.12.2022
Long COVID: New evidence for cause of fatigue syndrome
The diagnosis and treatment of long COVID syndrome (LCS) is still very difficult, and there is only little knowledge about the factors causing accompanying symptoms. Researchers at the Joint Metabolome Facility of the University of Vienna and the Medical University of Vienna have now presented new evidence of triggers for fatigue following SARS-COV-2 infection.

Pharmacology - Health - 15.12.2022
Inflammation may explain antidepressants’ link to preterm birth
Antidepressants can increase the risk of preterm birth, but it's unclear why. A new Yale study shows inflammation may play a key role. A Yale study has found that exposure to the common antidepressant Prozac provoked an inflammatory response in human fetal membranes, also known as the amniotic sac. The effect may reveal an underlying factor in what has been found to be an increased risk of preterm birth among those who use antidepressants during pregnancy - and possible therapeutic targets to reduce that risk.

Pharmacology - Health - 15.12.2022
Physician, heal thyself?
Research shows doctors and their families are less likely to follow guidelines about medicine. Why do the medically well-informed comply less often? Following established guidelines about prescription drugs would seem to be an obvious course of action, especially for the professionals that do the prescribing.

Health - Pharmacology - 14.12.2022
'Cocktail' vaccines could offer increased protection against future COVID-19 variants of concern
’Cocktail’ vaccines could offer increased protection against future COVID-19 variants of concern
COVID-19 vaccinations that combine two or more distinct variants of the SARS-CoV-2 virus could offer protection against both current and future -variants of concern-, say scientists at the University of Cambridge and Medical University of Innsbruck.
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