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Health - Pharmacology - 19.05.2022
New reporting guidelines developed to improve AI in healthcare settings
New reporting guidelines, jointly published and the BMJ by Oxford researchers, will ensure that early studies on using Artificial Intelligence (AI) to treat real patients will give researchers the information needed to develop AI systems safely and effectively. Artificial Intelligence in medicine has shown promising results in numerous simulation studies, but very few AI systems have yet been used in patient care.

Health - Pharmacology - 19.05.2022
New non-invasive method of risk assessment in liver disease
In a recent study, an interdisciplinary research team from MedUni Vienna showed that functional magnetic resonance imaging (fMRI) can be used as a non-invasive method for predicting complications in chronic liver disease. The scientists combined a simple risk stratification system developed at MedUni Vienna - the functional liver imaging score (FLIS) - with splenic diameter.

Health - Pharmacology - 19.05.2022
Study tests link between common blood pressure pills and breast cancer
Curtin researchers will examine if the long-term use of a popular blood pressure medication increased the risk of breast cancer in almost 200,000 women as part of a new project supported by the Federal Government. The new research, awarded an NHMRC Clinical Trials and Cohort Studies Grant, will investigate the link between the long-term use of calcium channel blockers and the risk of breast cancer by examining three internationally renowned Australian and Dutch longitudinal cohorts using state-of-the-art analytical techniques, which have not been used in this area before.

Health - Pharmacology - 18.05.2022
Antibiotics given shortly before caesarean birth not linked to asthma and eczema in young children
Antibiotics given to women before a caesarean birth have no effect on the risk of early childhood conditions, such as asthma or eczema, suggests a study by researchers at the Universities of Warwick and Birmingham. The research, published today (18 May 2022) in The BMJ, and funded by the National Institute for Health and Care Research, provides further evidence to support recommendations made by the National Institute for Health and Care Excellence (NICE).

Health - Pharmacology - 18.05.2022
Significant gains from computer-based depression treatment
Computer-based cognitive behavioral therapy was found to be significantly effective in treating depression in adults. (Andrea Piacquadio/Pexels) A new international collaborative study, involving multiple institutions including Western University, has found computer-based cognitive behavioural therapy (CCBT) has significantly greater impact in treating depression among adults than treatment as usual (TAU).

Health - Pharmacology - 18.05.2022
New research may explain unexpected effects of common painkillers
New research may explain unexpected effects of common painkillers
Non-steroidal anti-inflammatory drugs (NSAIDs) such as ibuprofen and aspirin are widely used to treat pain and inflammation. But even at similar doses, different NSAIDs can have unexpected and unexplained effects on many diseases, including heart disease and cancer. Now, a new Yale-led study has uncovered a previously unknown process by which some NSAIDs affect the body.

Health - Pharmacology - 17.05.2022
In osteoarthritis of the knee, the same treatment does not work for everyone. How to know when to operate?
Groundbreaking machine learning algorithm accurately predicts mental health crises The study was carried out by Koa Health together with Birmingham and Solihull Mental Health NHS Foundation Trust using anonymized data collected over seven years. Roger Garriga, a PhD candidate in the Department of Information and Communication Technologies at UPF, participated in the research.

Pharmacology - Health - 13.05.2022
Pharmacists at Higher Risk of Suicide than General Population
The pandemic put a spotlight on mental health and burnout within health care professions, but emerging research reveals these issues have been affecting health care workers for years, with suicide rates notably high among physicians and nurses. But until now, less was known about the mental health of pharmacists.

Pharmacology - Health - 13.05.2022
'Nanobodies' from llamas could yield targeted treatment methods for humans
’Nanobodies’ from llamas could yield targeted treatment methods for humans
'Nanobodies' from llamas could yield cell-specific medications for humans The nanobodies could help target issues such as irregular heart rhythms and could help prevent and control seizures In "proof of concept" experiments with mouse and human cells and tissues, Johns Hopkins Medicine researchers say they have designed tiny proteins, called nanobodies, derived from llama antibodies, that could potentially be used to deliver targeted medicines to human muscle cells.

Health - Pharmacology - 11.05.2022
The combination makes the difference: New therapeutic approach against breast cancer
The combination makes the difference: New therapeutic approach against breast cancer
Some breast tumors with certain genetic alterations are difficult to treat using existing therapies. Researchers at the University of Basel have now discovered an approach that involves a toxic combination with a second target gene in order to kill the abnormal cells. The first clinical trials could be starting soon.

Health - Pharmacology - 11.05.2022
Discovery reveals blocking inflammation may lead to chronic pain
Discovery reveals blocking inflammation may lead to chronic pain
Using anti-inflammatory drugs and steroids to relieve pain could increase the chances of developing chronic pain, according to researchers from McGill University and colleagues in Italy. Their research puts into question conventional practices used to alleviate pain. Normal recovery from a painful injury involves inflammation and blocking that inflammation with drugs could lead to harder-to-treat pain.

Pharmacology - Health - 10.05.2022
Why Australians take medicinal cannabis
Of the 248,000 scripts approved for Australians since the inception of the national medicinal cannabis scheme in 2016, many related to conditions for which the drug has limited evidence of efficacy, a new University of Sydney study shows. The first in-depth study of Australia's medicinal cannabis program, which began in 2016, shows the drug is being increasingly prescribed for various conditions.

Pharmacology - Health - 09.05.2022
Lymphomas: new model developed at the IOR against drug resistance
Lymphomas: new model developed at the IOR against drug resistance
The Lymphoma Genomics group, directed by Prof. Francesco Bertoni at the Institute of Oncology Research (IOR, affiliated to USI and member of Bios+), identified a new mechanism behind the resistance to the drug idelalisib, used in the treatment of patients with follicular lymphoma and marginal zone lymphoma.

Health - Pharmacology - 06.05.2022
Targeting Molecular Pathway that Causes Pulmonary Arterial Hypertension
UC San Diego researchers describe imbalance of opposing cell signals that cause deadly disease, and how a novel monoclonal antibody therapy might treat or prevent it Pulmonary arterial hypertension (PAH) is a type of high blood pressure in the lungs, in which blood vessels are narrowed, blocked or destroyed, causing the heart to work harder and, in time, result in cardiac weakness and failure.

Pharmacology - Health - 06.05.2022
Scientists closer to outsmarting malaria parasites
Researchers from The Australian National University (ANU) have discovered why malaria parasites are vulnerable to some drug ther apies but resistant to others , offering scientists another piece of the puzzle in the global fight against the disease. The ANU team has characterised two malaria proteins , known as PfMDR1 and PfCRT , t'hat work together to transport drugs away from areas where the y exert their killing effect and concentrate them in "safe zones" that ultimately rend er the treatment s'ineffective.

Pharmacology - Health - 05.05.2022
Small changes - but essential! How peptides are recognised in receptors
Small changes - but essential! How peptides are recognised in receptors
Researchers discover molecular mechanisms of signal recognition of the neuropeptide system The human body consists of trillions of cells that constantly communicate with each other. A central role in this communication process is played by receptor proteins on the cell surface. Since they often serve as drug targets, they have been the subject of intensive research.

Health - Pharmacology - 05.05.2022
Digital health support systems help improve health for people with breast cancer
A study has found people with breast cancer who received ongoing support through digital resources such as websites and mobile apps reported improved quality of life, and less stress and fatigue. People with breast cancer who accessed digital support systems such as websites and mobile apps overall found it was a valuable resource in between medical appointments, making them more confident in managing their health and improving their quality of life.

Life Sciences - Pharmacology - 05.05.2022
A paper of the Universitat de València and IIS La Fe about stem cells differentiation to hepatocytes appears on the cover of the Journal of Proteome Research
A paper of the Universitat de València and IIS La Fe about stem cells differentiation to hepatocytes appears on the cover of the Journal of Proteome Research
The research team of the Mixed Unit Universitat de Valéncia-IIS La Fe of Experimental Hepatology and Hepatic Transplantation has published a paper in the Journal of Proteome Research, a peer-reviewed scientific journal of the American Chemical Society.

Environment - Pharmacology - 05.05.2022
Our lifestyles are key contributors to river pollution - here is how social prescribing can help
Our lifestyles are key contributors to river pollution - here is how social prescribing can help
Home and lifestyle activities are major contributors to water quality. Social interventions may provide the most sustainable solution. Household and lifestyle activities are key contributors to water quality, according to new research from the University of Bath. Social interventions - such as social prescribing - may provide a more sustainable solution to this problem than improvements to wastewater treatment processes.

Health - Pharmacology - 04.05.2022
Influenza: A New Avenue for Developing Innovative Treatments
Influenza: A New Avenue for Developing Innovative Treatments
Seasonal influenza is a major public health issue because it continues to remain associated with considerable mortality, particularly among people who are elderly, immunocompromised, or both. It also has a significant socioeconomic cost. With vaccination and current treatments still being of limited efficacy, research teams are trying to develop new therapeutic approaches.
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