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Inserm press room - Institut national de la santé et de la recherche médicale press room Certain treatments to combat the Ebola virus, notably those based on monoclonal antibodies 1 , have increased the survival rate of patients suffering from the disease and are now recommended. Researchers from IRD, Inserm, ANRS Emerging Infectious Diseases and INRB have assessed, for the first time, the antibody response of survivors of the tenth Ebola epidemic in the Democratic Republic of Congo (DRC) who received specific anti-viral drugs.

Patients given transitional care before and during discharge from hospital - such as joint discharge planning follow up visits or phone calls - are less likely to be readmitted according to University of Manchester researchers. meta study of data from 126trials with 97, 408participants, published in JAMA Network Open today (30/11/23) showed the interventions were associated with significant reductions in the odds of readmissions at 180 days after discharge.

Increasing the amount of folate through our diet or taking supplements could help to reduce bowel cancer risk. These are the findings of new research , co-led by Dr Konstantinos Tsilidis from the School of Public Health at Imperial College London. It suggests that increasing the intake of folate - which can be found in leafy greens, such as spinach, cabbage and broccoli - could help to reduce the risk of colorectal cancer by up to 7%.

In today's medical landscape, antibiotics are pivotal in combatting bacterial infections. These potent compounds, produced by bacteria and fungi, act as natural defenses against microbial attacks. A team of researchers delved into the intricate world of glycopeptide antibiotics - a vital resource in countering drug-resistant pathogens - to uncover their evolutionary origins.

Slow waves that usually only occur in the brain during sleep are also present during wakefulness in people with epilepsy and may protect against increased brain excitability associated with the condition, finds a new study led by researchers at UCL.

Researchers at CHU Sainte-Justine find a way to use 3D printing to produce heart valves for eventual use in surgery on children with cardiac defects. In a breakthrough in pediatric cardiac science, Canadian researchers have successfully produced a bio-ink that could someday be used to print functional, durable heart valves, offering hope for improving the prognosis of children with heart defects.

MIT and MGH researchers design a local, gel-based drug-delivery platform that may provoke a system-wide immune response to metastatic tumors. For most metastatic cancer types, there are no reliably effective treatments. Therapies may slow the growth of tumors, but they will not eradicate them. Occasionally, however, treating a tumor in one location will cause untreated tumors elsewhere in the body to shrink or even regress completely - a dramatic but exceedingly rare phenomenon known as the abscopal effect.

Cruciate ligament injuries are among the most common injuries in sport. Researchers from the ZHAW and ZHdK have developed the ExerUp game in collaboration with a practice partner to help people return to their previous level of activity in addition to physiotherapy . A movement-based game is designed to support injured athletes after a cruciate ligament injury as part of physiotherapy and rehabilitation.

A new qualitative study from Bath psychologists suggests a lack of information and perceived necessity, as well as awkwardness, are impacting uptake of PrEP. Published on Thursday 30 November 2023 Last updated on Thursday 30 November 2023 Results of a qualitative research study into the uptake of PrEP - a drug which stops HIV infecting the body - suggests that more needs to be done to breakdown barriers to access for the potentially lifesaving medication.

Alzheimer's disease is a neurodegenerative condition that damages a person's ability to think, remember, and perform basic functions. According to the National Institutes of Health, Alzheimer's affects more than 6 million Americans, mostly ages 65 and older. Though the neurological damage from the disease is irreversible, its progression can be slowed by early interventions such as exercise and nutrition regimens.

A great number of health problems, and consequently the medical treatments for them, involve how blood flows through the body. Heart attacks are caused by restricted blood flow to the heart muscle. Many symptoms of diabetes are the result of damaged blood vessels. Tumors, meanwhile, often promote the growth of new vessels that deliver blood specifically to them.

Researchers said very high levels of HDL-C linked to dementia risk in this study were uncommon and not diet related, but more likely to reflect a metabolic disorder. The findings may help doctors to recognise a group of older patients potentially at risk of dementia, particularly in those aged 75 and older.

Flavonoids & Co: Microorganisms in the human gut utilise so-called beta-elimination to break down plant natural products and thus make them available to humans. Fruit and vegetables contain a variety of plant natural products such as flavonoids, which give fruits their colour and are said to have health-promoting properties.

University of Waterloo researchers are pioneering a method to detect breast cancer in women early enough for them to receive life-saving treatment. The innovative technology will be cheaper and safer than common cancer diagnostic tools. The innovative technology aims to be more accurate as well as cheaper to provide than today's most common diagnostic tools such as X-ray mammography, ultrasound and magnetic resonance imaging (MRI).

One in 200 newborns is admitted to a neonatal unit with sepsis caused by a bacteria commonly carried by their mothers - much greater than the previous estimate, say Cambridge researchers. The team has developed an ultra-sensitive test capable of better detecting the bacteria, as it is missed in the vast majority of cases.

UCLA researchers detail how prostate cancers grow more aggressively to evade treatment Science + Technology UCLA researchers detail how prostate cancers grow more aggressively to evade treatment Key takeaways Some prostate cancers evolve into a rare, treatment-resitant tumor known as a small cell neuroendocrine, or SCN, cancer.

Insights that pave the way for novel therapeutic approaches to tackle cancer, fibrosis, and many age-related conditions have been uncovered by a team of scientists, including researchers from UCL. The research, published in Nature Cell Biology and led by the Laboratory of Medical Sciences (MRC-LMS), identifies a new target for a class of drugs that selectively eliminate cells that are known to provoke inflammation.

A team of pharmacogenetics experts from the Universidad Autónoma de Madrid (UAM) and the Hospital Universitario de La Princesa have questioned the clinical utility of a biomarker that has been assumed to hold promise for personalized drug treatments. The results, published in the journal Clinical Pharmacology and Therapeutics , highlight the importance of rigorous and continuous evaluation of pharmacogenetic biomarkers prior to their implementation in clinical practice.

TUM researchers develop rapid test for severe infections Researchers have developed a method for assessing the number and structure of aggregated blood platelets (or thrombocytes) that can potentially help quantify the risk of a severe COVID-19 infection. As a result, they have identified a predictive biomarker for the seriousness of a COVID-19 infection.

A special gel with chemotherapy against peritoneal cancer, that is what start-up UPyTher is working on. The new technology could save many lives in the future. Each year, more than one million people worldwide contract peritoneal cancer. It is often the result of metastasis from colon, stomach, or ovarian cancer to the peritoneal cavity.