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Medicine / Pharmacology - Life Sciences - 17:30
Novartis phase II GEOMETRY mono-1 trial of investigational medicine capmatinib (INC280) shows positive results in patients with MET mutated advanced NSCLC
Novartis phase II GEOMETRY mono-1 trial of investigational medicine capmatinib (INC280) shows positive results in patients with MET mutated advanced NSCLC Phase II study efficacy data showed overall response rate of 72.0% and 39.1%, respectively, in treatment-naive and previously treated patients with advanced MET exon-14 skipping mutated non-small cell lung cancer (NSCLC)   Clinical findings from ongoing study indicate safety prof

Medicine / Pharmacology - Life Sciences - 07:02
New hope for cystic fibrosis
A new triple-combination drug treatment being trialled at the Mater Hospital in Brisbane could increase the life expectancy of patients with cystic fibrosis. Mater Research Institute-University of Queensland (MRI-UQ) researcher Dr Lucy Burr said seven patients were enrolled in Phase 2 of the clinical trial, which aimed to treat the underlying cause of cystic fibrosis.

Life Sciences - 18.10.2018
Missing-in-action MS genes
An international collaboration led by scientists at Yale has cracked a tough nut in multiple sclerosis: Where are all the genes? Previous work by the International Multiple Sclerosis Genetics Consortium (IMSGC) has identified 233 genetic risk variants. However, these only account for about 20% of overall disease risk, with the remaining genetic culprits proving elusive.

Life Sciences - 18.10.2018
University choice and achievement partly down to DNA
Research from King's College London has shown for the first time that genetics plays a significant role in whether young adults choose to go to university, which university they choose to attend and how well they do. Previous studies from King's College London have shown that genetics plays a major role in academic achievement at school, with 58% of individual differences between students in GCSE scores due to genetic factors.

Life Sciences - 18.10.2018
Europe’s first farmers travelled with their dogs
The first farmers who arrived into Europe had company when they travelled out of the Near East during the Neolithic expansion. Along with many other plants and animals, they also brought their dogs. The international collaboration conducted by researchers at École Normale Supérieure of Lyon, the University of Oxford, the National History Museum and the University of Rennes, has revealed that dogs have quite literally been man's best friend, from as far back as 9,000 years ago.

Life Sciences - Medicine / Pharmacology - 18.10.2018
Electrical properties of dendrites help explain our brain's unique computing power
Electrical properties of dendrites help explain our brain’s unique computing power
Neurons in human and rat brains carry electrical signals in different ways, scientists find. Neurons in the human brain receive electrical signals from thousands of other cells, and long neural extensions called dendrites play a critical role in incorporating all of that information so the cells can respond appropriately.

Life Sciences - Physics / Materials Science - 18.10.2018
What does graphene do in our lungs?
What does graphene do in our lungs?
Graphene has been hailed as the material of the future. As yet, however, little is known about whether and how graphene affects our health if it gets into the body. A team of researchers from Empa and the Adolphe Merkle Institute (AMI) in Fribourg have now conducted the first studies on a three-dimensional lung model to examine the behavior of graphene and graphene-like materials once they have been inhaled.

Life Sciences - Medicine / Pharmacology - 18.10.2018
Weight loss success linked with active self-control regions of the brain
Source: Cell Metabolism New research suggests that higher-level brain functions have a major role in losing weight. In a study among 24 participants at a weight-loss clinic, those who achieved greatest success in terms of weight loss demonstrated more activity in the brain regions of the lateral prefrontal cortex associated with self-control.

Life Sciences - Medicine / Pharmacology - 17.10.2018
New way to find relatives from forensic DNA
Investigators may be able to use forensic DNA to track down family members in public genealogy databases, creating new ways to generate leads while also raising issues about genetic privacy. It might seem like the only thing anyone could do with forensic DNA is match suspects to crime scenes. After all, agencies like the FBI don't track the same kind of genetic information as health or ancestry databases like GEDmatch or Ancestry.com.

Medicine / Pharmacology - Life Sciences - 17.10.2018
Unexpected role of enzyme may help develop anti-cancer drugs
A newly discovered role for the enzyme glutamine synthetase could have important implications for developing anti-cancer drugs according to a new UCL study. An intrinsic part of tumour growth is the sprouting of blood vessels, which supply cancerous tumours with the blood and energy that they need to survive.

Medicine / Pharmacology - Life Sciences - 17.10.2018
Probiotics and antibiotics create a killer combination
Probiotics and antibiotics create a killer combination
Delivered together, the two join forces to eradicate drug-resistant bacteria. In the fight against drug-resistant bacteria, MIT researchers have enlisted the help of beneficial bacteria known as probiotics. In a new study , the researchers showed that by delivering a combination of antibiotic drugs and probiotics, they could eradicate two strains of drug-resistant bacteria that often infect wounds.

Life Sciences - 17.10.2018
Bone cell response to mechanical force is balance of injury and repair
Researchers from McGill University and Shriners Hospitals for Children - Canada shed new light on the complex process involved in bone cells' response to mechanical injury Scientists have revealed the intricate process that bone cells use to repair themselves after mechanical injury, according to a study in the open-access journal eLife.

Life Sciences - Medicine / Pharmacology - 16.10.2018
Cellular clean-up crews linked to how body handles sugar
How our bodies handle glucose-the simple sugar that provides energy from the food we eat-appears to be intertwined with how cells keep themselves functioning normally, according to new University of Chicago research. The study, published with Scripps Research Institute scientists on Oct. 15 in Nature, found a link between the process that handles glucose in cells and the one that regulates detoxification.

Life Sciences - Computer Science / Telecom - 16.10.2018
Brain-inspired algorithm helps AI systems multitask and remember
Behind most of today's artificial intelligence technologies, from self-driving cars to facial recognition and virtual assistants, lie artificial neural networks. Though based loosely on the way neurons communicate in the brain, these "deep learning" systems remain incapable of many basic functions that would be essential for primates and other organisms.

Life Sciences - Medicine / Pharmacology - 16.10.2018
This RNA-based technique could make gene therapy more effective
This RNA-based technique could make gene therapy more effective
Biological engineers design RNA circuits that enable precise control over the dose of therapeutic protein a patient receives. Delivering functional genes into cells to replace mutated genes, an approach known as gene therapy, holds potential for treating many types of diseases. The earliest efforts to deliver genes to diseased cells focused on DNA, but many scientists are now exploring the possibility of using RNA instead, which could offer improved safety and easier delivery.

Life Sciences - 16.10.2018
A Selfish Gene Makes Mice into Migrants
A Selfish Gene Makes Mice into Migrants
House mice carrying a specific selfish supergene move from one population to another much more frequently than their peers. This finding of a study shows for the first time that a gene of this type can influence animal migratory behavior. It could help in dealing with invasive plagues of mice. Usually the cooperation of genes helps an organism to grow and flourish.

Medicine / Pharmacology - Life Sciences - 16.10.2018
What Pneumococcus "Says" to Make You Sick
Carnegie Mellon University researchers have identified a molecule that plays a key role in bacterial communication and infection. Their findings add a new word to pneumococcus' molecular dictionary and may lead to novel ways to manipulate the bacteria and prevent infection. The findings, from the lab of Associate Professor of Biological Sciences Luisa Hiller, are published in the Oct.

Life Sciences - Medicine / Pharmacology - 15.10.2018
Team develops technique to 'listen' to a patient's brain during tumour surgery
Team develops technique to ’listen’ to a patient’s brain during tumour surgery
Surgeons could soon eavesdrop on a patient's brain activity during surgery to remove their brain tumour, helping improve the accuracy of the operation and reduce the risk of impairing brain function. There's been huge progress in brain imaging and electrophysiology - our understanding of the electricity within our bodies - so why not use this information to improve brain surgery? Yaara Erez Patients with low-grade gliomas in their brains - a slow-spreading, but potentially life-threatening tumour - will usually receive surgery to have the tumour removed.

Medicine / Pharmacology - Life Sciences - 15.10.2018
New test rapidly identifies antibiotic-resistant 'superbugs'
New test rapidly identifies antibiotic-resistant ’superbugs’
Click to share on Google+ (Opens in new window) Click to share on Reddit (Opens in new window) Click to print (Opens in new window) When you get sick, you want the right treatment fast. But certain infectious microbes are experts at evading the very anti-bacterial drugs designed to fight them. A simple and inexpensive new test developed by UC Berkeley researchers can diagnose patients with antibiotic-resistant strains of bacteria in a matter of minutes.

Life Sciences - Environment - 15.10.2018
Diversity is key to sustainability for local chicken farming in Africa
PA 204/18 Adopting a more local and flexible approach to sustainable development could be key to boosting the productivity of small-scale farms in Africa, a study involving researchers at the University of Nottingham has found. The research, led by the University of Liverpool and in collaboration with UK and African partners, reveal village chicken populations in Ethiopia to be genetically diverse and highly adapted to their local physical, cultural and social environments.
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