science wire

A new drug combination could significantly delay the progression of a life-threatening form of prostate cancer in men with specific genetic mutations, finds a major international trial led by UCL researchers. The Phase III AMPLITUDE trial, published in Nature Medicine , tested the addition of niraparib, a type of targeted cancer drug known as a PARP inhibitor 1 , to the standard treatment of abiraterone acetate and prednisone (AAP).

For the first time, the OHCAO team at University of Warwick have published national data for children who suffer an out-of-hospital cardiac arrest, underscoring urgent need for CPR training.

Dr Elizabeth Rosser (UCL Division of Medicine) explores the symptoms, complications and treatments for lupus, an autoimmune disease which celebrity Selena Gomez suffers from as well as an estimated five million people worldwide.

Three recent studies examine pesticide pollution in Swiss streams and rivers. With comprehensive screening of over 250 pesticides, they show which of them occur in water bodies and which pose the highest risks to aquatic organisms The studies also investigated the applications from which particularly risk-relevant pesticides originate and the routes by which they enter water bodies - an important basis for reducing the pollution of water bodies by these substances in a targeted manner.

Study on "Freezing of Gait" aims to use socks to help sufferers In widespread diseases such as diabetes, cancer or Parkinson's, a significant proportion of research activity is carried out in the fields of medicine or pharmacology. However, other branches of research play an important role in preventing and dealing with everyday symptoms.

Breast cancer survivors with severe menopausal symptoms should be supported to make an informed decision about whether to have hormone replacement therapy or not, according to an interdisciplinary panel of experts including researchers from UCL.

A £2.8 million grant to combat health inequalities in patients having major surgery has been awarded to a team of clinicians and researchers at UCL and UCLH.

More than one million people a year are now being referred by GPs to social prescribing services, according to a new study led by researchers at UCL.

They are meticulously listed on every package insert and information sheet-the risks and side effects of drug or surgical therapy.

Patients and staff say that they'd welcome AI in online GP consultations if it supports rather than replaces doctors, according to a new Manchester and Cambridge study.

World-leading Alzheimer's disease experts, including UCL scientists, are calling for rapid reform in healthcare systems, public policy, and societal attitudes, in order to fully realise the potential of groundbreaking new medications.

Five-year multicentre randomized trial will include up to 4,800 patients across more than 100 dialysis units in Canada Researchers at Western's Schulich School of Medicine & Dentistry and London Healt

An enhanced computer model is now helping to provide fresh insights into cancer-cell growth and how it can be stopped.

A novel treatment for Leber's Hereditary Optic Neuropathy (LHON), a rare genetic disease that can lead to sudden loss of vision, has been approved for NHS patients following a successful clinical trial co-led by UCL and Moorfields researcher.

With this year's motto "Safe care for every newborn and every child", International Patient Safety Day 2025 is focusing on young patients.

A major UCL-led clinical trial, aiming to transform the diagnosis of Alzheimer's disease through a simple blood test, is now welcoming its first participants who will be recruited via memory clinics across the UK.

A quicker, cheaper MRI scan was just as accurate at diagnosing prostate cancer as the current 30-40 minute scan and should be rolled out to make MRI scans more accessible to men who need one, according to clinical trial results led by UCL, UCLH and the University of Birmingham.

A new study by Associate Professor Vladimir Karamychev of Erasmus School of Economics and Jurjen Kamphorst (Dutch Authority for Consumers and Markets) sheds light on the hidden dynamics driving high drug prices.

A major UK study, led by researchers at the University of Oxford's Nuffield Department of Primary Care Health Sciences , Oxford University Hospitals NHS Foundation Trust , the National Institute for Health and Care Research (NIHR) Oxford Biomedical Research Centre , and Oxford Cancer , has provided the most comprehensive analysis to date of a cancer diagnosis pathway for patients presenting with non-specific symptoms (NSS), such as unexplained weight loss or fatigue.

An international group of researchers has developed a new tool which can help identify problematic randomised controlled trials (RCTs), including fraudulent studies, where there are serious concerns about trustworthiness.

VUB-UGent research emphasises the importance of expert advice for young parents The use of thickeners in baby food is widespread, both in commercial formula and in additives added by parents themselves, such as starch or locust bean gum.

A UK-wide research team, led by the University of Oxford's Nuffield Department of Surgical Sciences , has launched a major international study to improve surgical treatment for people suffering from

Scientists have found a way to stop brain cancer cells spreading by essentially 'freezing' a key molecule in the brain.

A new treatment has been shown to significantly lower blood pressure in people whose levels stay dangerously high, despite taking several existing medicines, according to the results of a Phase III clinical trial led by a UCL Professor. Globally around 1.3 billion people have high blood pressure (hypertension), and in around half of cases the condition is uncontrolled or treatment resistant.

A study by USI, supported by the Swiss National Science Foundation and led by Peter J. Schulz, Full Professor and researcher at the Faculty of Communication, Culture, and Society, shows that d

Testing the molecular profile of tumours identifies which patients with advanced prostate cancer are more likely to benefit from chemotherapy and live longer, sparing patients less likely to benefit from unpleasant side effects, according to a new study led by UCL researchers.

Researchers from the Royal Veterinary College (RVC), in collaboration with the University of Veterinary Medicine and the University of Natural Resources and Life Sciences, both in Vienna, have developed the first laboratory-made vaccine to protect livestock against the Barber's Pole worm - a highly damaging gastrointestinal parasite most commonly found in sheep and goats.