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Health - Life Sciences - 19.07.2024
Turning off inflammatory protein extends healthy lifespan in mice
Turning off inflammatory protein extends healthy lifespan in mice
Scientists have discovered that 'turning off' a protein called IL-11 can significantly increase the healthy lifespan of mice by almost 25%. Researchers in the UK and Singapore have found that targeting the production of a key inflammatory protein in mice can extend their lifespan, reduce age-related disease and make older animals less frail.

Health - Life Sciences - 19.07.2024
Enhancing breast cancer diagnosis and treatment
Enhancing breast cancer diagnosis and treatment
Addressing problems with diagnosing and treating breast cancer, scientists at EPFL have developed EMBER, a tool that integrates breast cancer transcriptomic data from multiple databases. EMBER can improve precision oncology by accurately predicting molecular subtypes and therapy responses. Breast cancer is the most frequently diagnosed cancer worldwide.

Life Sciences - Health - 18.07.2024
Analysing internal world models of humans, animals and AI
Analysing internal world models of humans, animals and AI
Freiburg researchers develop new formal description of internal world models, thereby enabling interdisciplinary research A team of scientists led by Ilka Diester , Professor of Optophysiology and spokesperson of the BrainLinks-BrainTools research centre at the University of Freiburg, has developed a formal description of internal world models and published it in the journal Neuron .

Health - Life Sciences - 18.07.2024
A less burdensome approach to sickle cell treatment
Gene-editing approach could offer new hope to sickle cell patients Johns Hopkins team's innovative nanoparticle approach aims to reduce side effects and treatment burden Current gene therapies to treat sickle cell disease are complex, time-consuming, and are sometimes linked to serious side effects like infertility or blood cancer.

Life Sciences - 17.07.2024
How star-shaped cells increase flexible learning
How star-shaped cells increase flexible learning
Bonn researchers solve the hidden mystery of the role of astrocytes for learning processes and memory in the brain Star-shaped glial cells, so-called astrocytes, are more than just a supporting cell of the brain. They are actively involved in learning processes and interact with the nerve cells. But what exactly is it that astrocytes do? Researchers at the University Hospital Bonn (UKB) and the University of Bonn are using a biophysical model to clarify how astrocytes interact with nerve cells to regulate rapid adaptation to new information.

Environment - Life Sciences - 17.07.2024
Logged forests can still have ecological value - if not pushed too far
Logged forests can still have ecological value - if not pushed too far
Researchers have analysed data from 127 studies to reveal 'thresholds' for when logged rainforests lose the ability to sustain themselves. The results could widen the scope of which forests are considered 'worth' conserving, but also show how much logging degrades forests beyond the point of no return.

Health - Life Sciences - 17.07.2024
Scientists make breakthrough in development of fridge-free storage for vital medicines
Scientists make breakthrough in development of fridge-free storage for vital medicines
Scientists have developed a new approach to store and distribute crucial protein therapeutics without the need for fridges or freezers. The breakthrough, published in the journal Nature , could significantly improve accessibility of essential protein-based drugs in developing countries where cold storage infrastructure may be lacking, helping efforts to diagnose and treat more people with serious health conditions.

Life Sciences - Health - 17.07.2024
Addition to the CRISPR Toolbox: Teaching Gene Scissors to Detect RNA
Addition to the CRISPR Toolbox: Teaching Gene Scissors to Detect RNA
A team at the Helmholtz Centre for Infection Research in Würzburg, Germany, led by RNA expert Chase Beisel, has developed a new technology for the precise detection of RNA using DNA-cutting Cas12 nucleases. CRISPR-Cas systems, defense systems in bacteria, have become a plentiful source of technologies for molecular diagnostics.

Life Sciences - Pharmacology - 17.07.2024
Factors enabling a human RNA virus to mutate and facilitate its transmission identified
The Institute for Integrative Systems Biology (UV-CSIC) has conducted the first comprehensive analysis of all mutations in the protein set of coxsackievirus B3, which causes severe heart inflammation. The findings, published in Plos Biology, will help to identify regions of the virus genome with low tolerance to mutations, facilitating the development of drugs targeting these areas.

Health - Life Sciences - 17.07.2024
Multiple concussions in rugby players change proteins in their blood
A new study shows that retired rugby players who have suffered multiple concussions have abnormal levels of certain proteins in their blood. This may make them more prone to developing diseases such as motor neurone disease (MND). This is what new research led by our bioscientists has found as part of the UK Rugby Health project.

Life Sciences - Health - 17.07.2024
'Paleolithic' diets are not without risks
’Paleolithic’ diets are not without risks
A study highlights the toxicity risks of high-protein diets, which can lead to severe neurological disorders. High-protein diets, known as ''Paleolithic diets'', are popular. Using mouse models, scientists at the University of Geneva have studied their impact. While effective in regulating weight and stabilizing diabetes, these diets are not without risks.

Microtechnics - Life Sciences - 17.07.2024
Ant insights lead to robot navigation breakthrough
Ant insights lead to robot navigation breakthrough
Have you ever wondered how insects are able to go so far beyond their home and still find their way? The answer to this question is not only relevant to biology but also to making the AI for tiny, autonomous robots. TU Delft drone-researchers felt inspired by biological findings on how ants visually recognize their environment and combine it with counting their steps in order to get safely back home.

Health - Life Sciences - 17.07.2024
Scientists make breakthrough in fridge-free storage for vital medicines
Scientists have developed a new approach to store and distribute crucial protein therapeutics without the need for fridges or freezers. The breakthrough, published in the journal Nature , could significantly improve accessibility of essential protein-based drugs in developing countries where cold storage infrastructure may be lacking, helping efforts to diagnose and treat more people with serious health conditions.

Life Sciences - Health - 17.07.2024
Study addresses long-standing diversity bias in human genetics
Study addresses long-standing diversity bias in human genetics
New study addresses long-standing diversity bias in human genetics Catalog of data generated by Johns Hopkins scientists includes groups traditionally neglected in research, should yield more accurate insights into genetic factors driving human diversity Most research in human genetics has historically focused on people of European ancestries-a long-standing bias that may limit the accuracy of scientific predictions for people from other populations.

Life Sciences - Health - 16.07.2024
First bone marrow model which supports human stem cells
Scientists develop first bone marrow model which supports human stem cells Scientists have created the first bioengineered bone marrow model which can support the type of human stem cells that are crucial for bone marrow transplants and in vitro study work. The research - published in Nature Communications and led by the University of Glasgow - replicates key aspects of the human bone marrow microenvironment, to enable the support of rare long-term hematopoietic stem cells, or LT-HSCs.

Health - Life Sciences - 16.07.2024
Unraveling amyloid fibrils
Unraveling amyloid fibrils
Researchers at EPFL have discovered how amyloid fibrils form complex structures, shedding light on diseases like Alzheimer's and opening new doors in material science. Amyloids are protein aggregates that can form in the body, sometimes leading to diseases like Alzheimer's. These fibrils can adopt multiple shapes, known as "polymorphs", which complicate our understanding of their role in health and disease.

Life Sciences - Environment - 16.07.2024
Insight into one of life's earliest ancestors revealed in new study
Insight into one of life’s earliest ancestors revealed in new study
The Last Common Universal Ancestor (LUCA), from which life evolved into bacteria, plants and animals, was older and more complex than previously thought. An international team of researchers, including Dr James Clark from the Milner Centre for Evolution at the University of Bath, has shed light on Earth's earliest ecosystem, showing that within a few hundred million years of planetary formation, life on Earth was already flourishing.

Health - Life Sciences - 15.07.2024
Autoantibodies Behind Lifelong Risk of Viral Infections
A new study shows that about two percent of the population develop autoantibodies against type 1 interferons, mostly later in life. This makes individuals more susceptible to viral diseases like COVID-19. The study, conducted by researchers together with a USZ team, is based on an analysis of a large collection of historical blood samples.

Health - Life Sciences - 15.07.2024
Study sheds light on origins of schizophrenia in the brain, offering hope for targeted treatments and better diagnosis
Gradual reopening continues on downtown campus. See Campus Public Safety website for details. La réouverture graduelle du campus du centre-ville se poursuit. Complément d'information : Direction de la protection et de la prévention.

Life Sciences - Pharmacology - 15.07.2024
Anesthesia drug induces unconsciousness
Propofol, a drug commonly used for general anesthesia, derails the brain's normal balance between stability and excitability. There are many drugs that anesthesiologists can use to induce unconsciousness in patients. Exactly how these drugs cause the brain to lose consciousness has been a longstanding question, but MIT neuroscientists have now answered that question for one commonly used anesthesia drug.
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