John Wood, UCL Wolfson Institute for Biomedical Research
Medical research charity Arthritis Research UK has awarded researchers at UCL and the University of Nottingham a grant of £800,000 to develop new treatments for severe arthritis pain. The research could be of benefit to the millions of people with arthritis around the world who experience disability and distress as a result of their pain. The team at UCL and the Arthritis Research UK Pain Centre at the University of Nottingham will use the funds for a four year study to look at the role of the proteins and molecules involved in causing severe pain in people with osteoarthritis and rheumatoid arthritis. Currently people experiencing pain associated with osteoarthritis and rheumatoid arthritis are offered pain relieving drugs, such as steroids or ibuprofen, which work by blocking the disease inflammation. Although these drugs work well for people experiencing low level pain, they can have little impact for people experiencing severe pain. The team, led jointly by Professor John Wood at the UCL Wolfson Institute for Biomedical Research and Professor David Walsh, director of the Arthritis Research UK Pain Centre at the University of Nottingham, hope their findings may lead to the development of new drug treatments which are more effective in fighting arthritis pain. This grant will help increase our understanding of the exact role of the proteins and molecules involved in causing severe pain, which remain largely unknown.
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