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Health - Pharmacology - 16.06.2021
RECOVERY trial Regeneron’s monoclonal antibody combination reduces deaths for hospitalised COVID-19 patients
The Randomised Evaluation of COVID-19 Therapy (RECOVERY) trial has demonstrated that the investigational antibody combination developed by Regeneron reduces the risk of death when given to patients hospitalised with severe COVID-19 who have not mounted a natural antibody response of their own. The treatment uses a combination of two monoclonal antibodies (casirivimab and imdevimab, known as REGEN-COV in the US) that bind specifically to two different sites on the coronavirus spike protein, neutralising the ability of the virus to infect cells.

Health - Pharmacology - 16.06.2021
Treating Needle Fears May Reduce COVID-19 Vaccine Hesitancy Rates by 10%
A new large-scale study shows that a quarter of the UK adult population screens positive for a potential injection phobia.

Health - Pharmacology - 16.06.2021
Human milk from women infected and vaccinated for coronavirus has antibodies against COVID-19
Human milk from women infected and vaccinated for coronavirus has antibodies against COVID-19
Human milk from infected women and vaccinated for coronavirus has antibodies against COVID-19, according to two published studies in the medRxiv repository and launched by the scientific consortium M

Health - Pharmacology - 16.06.2021
Water injections could be used to relieve labour pains
The effectiveness of using sterile water injections for labour contraction pain will be tested by an international collaboration of researchers, thanks to federal funding.

Pharmacology - Health - 16.06.2021

Health - Pharmacology - 15.06.2021
Major new study could help protect millions of people with type 2 diabetes from cardiovascular disease | University of Oxford
A new study led by the Nuffield Department of Population Health at the will research whether a daily tablet could help protect the millions of people worldwide with type 2 diabetes from developing cardiovascular disease.

Campus - Pharmacology - 15.06.2021

Health - Pharmacology - 14.06.2021

Pharmacology - Health - 11.06.2021
Novartis investigational oral therapy iptacopan (LNP023) shows benefit as monotherapy in treatment-na´ve patients with rare and life-threatening blood disorder paroxysmal nocturnal hemoglobinuria
First-in-class, oral, targeted factor B inhibitor iptacopan substantially reduced both intraand extravascular hemolysis when given as monotherapy in a Phase II study of anti-C5 na´ve paroxysmal noctu

Health - Pharmacology - 11.06.2021

Pharmacology - Health - 11.06.2021
Roche announces data at EHA2021 reinforcing efficacy of Venclexta/Venclyxto combinations in chronic lymphocytic leukaemia and acute myeloid leukaemia
Four-year follow-up analysis from the phase III CLL14 study showed progression-free survival rate of 74.0% in previously untreated patients with chronic lymphocytic leukaemia (CLL) three years

Health - Pharmacology - 11.06.2021
AI Predicts How Patients with Viral Infections, Including COVID-19, Will Fare
Gene expression patterns associated with pandemic viral infections provide a map to help define patients' immune responses, measure disease severity, predict outcomes and test therapies - for current and future pandemics Researchers at University of California San Diego School of Medicine used an artificial intelligence (AI) algorithm to sift through terabytes of gene expression data — which genes are "on" or "off" during infection — to look for shared patterns in patients with past pandemic viral infections, including SARS, MERS and swine flu.

Health - Pharmacology - 09.06.2021
Averting an antibiotics apocalypse: major funding announced to tackle resistance to antibiotics
Averting an antibiotics apocalypse: major funding announced to tackle resistance to antibiotics
A cross-disciplinary team from the Universities of Oxford, Ulster and UCL today announced major funding from EPSRC, part of UK Research and Innovation (UKRI), to tackle the growing challenge of Antimicrobial Resistance (AMR).

Health - Pharmacology - 09.06.2021
Novel UCL developed cancer drug to be trialled in humans
Patients with a number of Non-Hodgkin lymphoma (NHL) subtypes will be used to trial a novel cancer treatment developed by researchers at UCL, which holds "great promise" for several incurable conditions.

Pharmacology - Health - 08.06.2021
Low doses of ’laughing gas’ could be effective in treating severe depression
In phase 2 clinical trials, researchers found nitrous oxide improved depression for over two weeks In 2015, University of Chicago Prof. Peter Nagele became interested in exploring the effects of nitrous oxide, commonly known as "laughing gas"-not for dental procedures, as most people associate it with, but for treating severe depression.

Health - Pharmacology - 08.06.2021
RECOVERY trial finds aspirin does not improve survival for patients hospitalised with COVID-19
RECOVERY trial finds aspirin does not improve survival for patients hospitalised with COVID-19
The RECOVERY trial was established as a randomised clinical trial to test a range of potential treatments for patients hospitalised with COVID-19.

Health - Pharmacology - 08.06.2021
What’s the Delta COVID variant found in Melbourne? Is it more infectious and does it spread more in kids?
Victoria's current COVID outbreak took another turn last week when a new variant was discovered by health authorities.

Health - Pharmacology - 08.06.2021
Sydney experts spearhead COVID-19 vaccine research
A leading group of NSW experts, including from the University of Sydney, have received funding from the NSW Government to pioneer Australia-first research to inform vaccine policy in the state and beyond.

Pharmacology - Health - 07.06.2021
Novartis announces new interim analysis Phase II data for iptacopan in rare kidney disease C3 glomerulopathy (C3G)
Data shows investigational iptacopan improved estimated glomerular filtration rate (eGFR) slope and stabilized kidney function in patients with C3G 1 ; Phase III clinical trial to start in 2021 Resul

Pharmacology - Health - 07.06.2021
Approval for New Alzheimer’s Drug Developed at UZH
The active ingredient aducanumab, which was discovered at the University of Zurich, has been approved for use in the United States as a treatment for Alzheimer's disease.

Health - Pharmacology - 07.06.2021
Alternative treatments to combat drug-resistant bacteria focus of major new study
Alternative treatments to combat drug-resistant bacteria focus of major new study
The growing challenge of Antimicrobial Resistance (AMR), where germs like bacteria and fungi develop the ability to defeat the drugs designed to kill them, is at the heart of a new funding collaboration involving UCL researchers.

Pharmacology - Health - 06.06.2021
Novartis announces iptacopan met Phase II study primary endpoint in rare kidney disease IgA nephropathy (IgAN)
Phase II primary endpoint results for investigational iptacopan in IgAN demonstrated effective and clinically meaningful reduc tion of proteinuria 1 - a key risk predictor in kidney disease progressi

Pharmacology - Health - 04.06.2021
Roche presents latest advances with immunotherapies in non-Hodgkin lymphoma
Data for investigational CD20xCD3 bispecific antibodies and new combination regimens with Polivy showed enhanced clinical benefits for people with non-Hodgkin lymphoma in early studies Basel, 4 June

Health - Pharmacology - 04.06.2021
Pfizer-BioNTech vaccine recipients have lower antibody levels targeting the Delta variant
Pfizer-BioNTech vaccine recipients have lower antibody levels targeting the Delta variant
Levels of antibodies in the blood of vaccinated people that are able to recognise and fight the new SARS-CoV-2 Delta variant first discovered in India (B.1.617.2) are, on average, lower than those against variants previously circulating in the UK, finds a new study involving UCL.

Pharmacology - Health - 04.06.2021
Novartis announces Tabrecta first published overall survival and updated overall response data in patients with METex14 metastatic NSCLC
Tabrecta (capmatinib) showed a median overall survival (OS) of 20.8 months in treatment-na´ve patients and 13.6 months in previously-treated patients in first published mature data 1,2

Pharmacology - Health - 03.06.2021
Novartis reports clinically relevant improvement in median overall survival data in final analysis of pivotal NETTER-1 study with targeted radioligand therapy Lutathera
At final analysis, study showed clinically relevant improvement in median overall survival with a difference of 11.7 months between arms (Hazard ratio (HR): 0.84 with 95% CI: (0.

Pharmacology - Health - 03.06.2021
Researcher-led International Task Force unveils first-of-its kind standards for treatment of obsessive-compulsive disorder
McGill researcher-led International Task Force unveils first-of-its kind standards for treatment of obsessive-compulsive disorder By David McFadden Listed by the World Health Organization among the t

Pharmacology - Health - 02.06.2021
Novartis Kisqali reports longest median overall survival in postmenopausal HR+/HER2- metastatic breast cancer patients
MONALEESA-3 median overall survival (OS) results of 53.7 months underscore that Kisqali offers more life to postmenopausal women with HR+/HER2- metastatic breast cancer (MBC) in addition to th

Health - Pharmacology - 01.06.2021
The simulated patient
The simulated patient
Digital twins enable customized medical therapies. researchers have now modeled several hundred such avatars based on real people and treated them experimentally.

Pharmacology - Health - 01.06.2021
Novartis Cosentyx receives FDA approval for treatment of children and adolescents with moderate to severe plaque psoriasis
Approval for moderate to severe pediatric patients six years and older is based on pivotal trial data showing Cosentyx demonstrated superior improvements of skin symptoms compared to placebo 1 The sa

Health - Pharmacology - 01.06.2021
Immunity experts move into state-of-the-art facilities
Immunity experts move into state-of-the-art facilities
Scientists at UCL are preparing to move into a new ultra-modern research facility which will enable them to work more closely with clinicians to develop revolutionary treatments and cures for some of the most devastating diseases of the immune system.

Health - Pharmacology - 28.05.2021

Life Sciences - Pharmacology - 28.05.2021
World-first multiple sclerosis global image database launched
World-first multiple sclerosis global image database launched
A world-first global MS image database launched in Australia today complementing MSBase, the largest clinical MS patient registry, to advance MS research with potential for earlier diagnosis and precision monitoring.

Health - Pharmacology - 27.05.2021
With herd immunity elusive, vaccination best defense against COVID-19, Stanford epidemiologist says
Epidemiology expert Julie Parsonnet warns that COVID-19 vaccine hesitancy has probably made herd immunity unattainable, which makes vaccination all the more important for personal health.

Health - Pharmacology - 27.05.2021
Research aims for best ways to treat COVID-19 at home
While more than 125 million Americans have received full doses of the COVID-19 vaccine, thousands of people in the U.S. are being diagnosed each day with the disease.

Health - Pharmacology - 26.05.2021
COVID-19 symptoms linger for months in majority of hospitalized patients, Stanford study finds
More than 70% of COVID-19 patients in studies - most of whom were hospitalized - reported 84 different symptoms and signs months after they became ill.

Health - Pharmacology - 26.05.2021
Almost half of patients with inoperable pancreatic cancer are not prescribed essential medication
A University of Birmingham-led study has found almost half of people diagnosed within inoperable pancreatic cancer are not prescribed inexpensive yet essential tablets without which they cannot digest food - placing them at risk of starvation or being less able to tolerate treatment.

Life Sciences - Pharmacology - 26.05.2021
Covid-19 vaccine: Common stroke symptoms must be ’urgently evaluated’
UCL and UCLH neurologists have published the first clinical observations of patients who experienced an ischaemic stroke, the most common form of stroke, following an Oxford AstraZeneca vaccine.
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