science wire

The University of Oxford in partnership with the Coler Lab at Seattle Children's Research Institute (SCRI) has begun a new clinical trial called TB045, which aims to test tuberculosis (TB) vaccine sa

The University of Oxford in partnership with the Coler Lab at Seattle Children's Research Institute (SCRI) has begun a new clinical trial called TB045, which aims to test tuberculosis (TB) vaccine sa

Researchers at the University of Glasgow have secured industry sponsorship to accelerate the pre-clinical development of a novel precision therapy which may one day offer a new treatment option for patients living with cancers such as Acute Myeloid Leukaemia (AML) and Neuroblastoma.

GPs who conduct their surgeries in the flesh are more likely to have satisfied patients according to a new study by University of Manchester researchers.

A technique to improve the precision of prostate cancer surgery means that almost twice as many men preserve their erectile function compared to those undergoing standard surgery, according to results from a clinical trial led by researchers from UCL and UCLH.

UCalgary researchers reveal biological differences between the sexes when it comes to chronic pain A new study led by University of Calgary Tuan Trang , PhD, may help to explain why there is an over-representation of women experiencing chronic pain compared to men.

Janus kinase inhibitors (JAKis) are an important treatment option for people with chronic inflammatory diseases such as rheumatoid arthritis, psoriasis, Crohn's disease or ulcerative colitis.

In an to Health Secretary Wes Streeting, dentists have warned that a failure to fully meet demand for urgent dental care can only increase the pressures on our health service, as antibiotics become a substitute for treatment.

Five years later, what impact has the COVID-19 pandemic had on the healthcare system? What questions and areas of research remain unresolved? Prof. Enos Bernasconi, Full Professor at the Faculty of Biomedical Sciences of Università della Svizzera italiana (USI), Prof. Davide Robbiani, Full Professor at USI Faculty of Biomedical Sciences and Director of the Institute for Research in Biomedicine (IRB) , and Prof. Emiliano Albanese, Full Professor at USI Faculty of Biomedical Sciences tackled the topic in two reports on Quotidiano (RSI).

FORESIGHT consortium stimulates molecular imaging in the development of new immunotherapy drugs and the matching of existing drugs with patients.

Lupus is an autoimmune disease where the body's immune system attacks its own tissues and organs, causing inflammation and damaging organs. A new study co-led by the University of Zurich has now shown that the natural active ingredient gluconolactone restores immune regulation, reduces inflammation and could enable targeted therapy with fewer side effects.

Research by Aziz Debain (Frailty & Resilience in Ageing Research Unit, VUB & Geriatrics Department, UZ Brussels) sheds new light on the impact of medication on the autonomic nervous system in older adults. The study, conducted with over 400 participants over a two-year period, shows that certain medications nearly triple the risk of frailty in older individuals.

PSMA PET/CT trial will scan up to 1000 men in the UK A new kind of scan that could be key to improving the treatment of high-risk prostate cancer is about to be tested in a new £1.89 million clinical trial led by Professor Hash Ahmed and funded by Prostate Cancer UK.

Public Health Agency of Canada selects University of Calgary to lead national surveillance program The University of Calgary is leading one of the most comprehensive, active, hospital-based infectious disease surveillance systems for children in Canada that the country has ever had.

High levels of ammonia kill liver cells by damaging the mitochondria that power the cells. But this can be prevented using an existing drug due to start clinical trials, finds a new study in mice led by researchers from UCL.

A study led by the University of Geneva and the HUG shows that an interval of at least 50 days between stopping immunotherapy and liver transplantation significantly reduces the risk of rejection. Hepatocellular carcinoma (HCC) is the most common type of liver cancer in Switzerland and worldwide. Immunotherapy through immune checkpoint inhibitors (ICI) combined with a liver transplant (see below) could constitute a solution for treating even advanced stages.

Calgary family's $2M gift helps Oncology Outcomes (O2) team make data research discoveries benefiting breast, kidney and lung cancer patients An innovative data research program at the University of C

A new nationwide study, focused on children and young people with epilepsy, will provide doctors and families with vital new information on living with the neurological condition. The new Epi-Scot (Epilepsy, Precision Investigation, Stratified Care and Outcomes of Therapy) Study will be open to all children in Scotland, aged 16 years-old and under, who are given a diagnosis of epilepsy on or after 1 March 2025.

A new AI model can flag female patients who are at higher risk of heart disease based on an electrocardiogram (ECG). The researchers say the algorithm, designed specifically for female patients, could enable doctors to identify high-risk women earlier, enabling better treatment and care. Details are published today in Lancet Digital Health.

A team of researchers from UCL and King's College London has developed an AI-powered tool that can detect 64% of brain abnormalities associated with epilepsy, that were missed by human radiologists. MELD Graph is an AI tool that could drastically change the care of 30,000 patients in the UK and 4 million patients worldwide who have focal cortical dysplasia (FCD) - a leading cause of epilepsy.

The BMBF is funding a research project by the University of Bonn and ESQlabs that is aiming to improve colon cancer treatment.

Diseases caused by Candida are among the most common fungal infections worldwide / The new guideline was developed over four years by a team of more than one hundred experts from 35 countries, includ

New study suggests that the benefits of prescribing anticoagulation drugs to older people outweigh the potential risks. For patients with atrial fibrillation, the risk of stroke or heart attack from stopping anticoagulants usually outweighs the risk of bleeding, according to new findings from the University of Bath.

By Benjie Coleman , Laura Gallagher , Ryan O'Hare , Sylvia Garvin , Samantha Rey Here's a batch of fresh news and announcements from across Imperial.

Who hasn't been there? The big meal is over, you're full, but the craving for sweets remains. Researchers from the Max Planck Institute for Metabolism Research in Cologne have now discovered that what we call the "dessert stomach" is rooted in the brain.

Vaccinations alone may not be enough to protect people with compromised immune systems from infection, even if the vaccine has generated the production of antibodies, new research from the University of Cambridge has shown.

Providing tuberculosis (TB) patients with advice and money can help them to finish their treatment and recover, finds a new study involving UCL researchers. The research, published in The Lancet Infectious Diseases , demonstrated that patients who received counselling and cash incentives (around $10) for turning up to appointments on time, had a 52% lower relative risk of having an unsuccessful treatment outcome.

Responding to an Nature article that reported the growth of heart muscle patches from precursor cells to mend the damaged monkey hearts, Professor John Martin (UCL Medicine) cautions scepticism in The Conversation. There are many difficulties in converting any biological research into a medicine that will treat patients.

The GLP-1 drug, exenatide, has no positive impact on the movement, symptoms or brain imaging of people with Parkinson's disease, finds a new study led by UCL researchers. The world's largest and longest trial of exenatide in people with Parkinson's disease was funded by the National Institute for Health & Care Research (NIHR) with support for sub-studies from Cure Parkinson's and Van Andel Institute.

The future of medicine may very well lie in the personalization of health care-knowing exactly what an individual needs and then delivering just the right mix of nutrients, metabolites, and medications, if necessary, to stabilize and improve their condition. To make this possible, physicians first need a way to continuously measure and monitor certain biomarkers of health.

TU/e's Precision Medicine group develops nature-inspired nanotechnology to use genetic drugs as immunotherapy.

According to the WHO, 30 to 50 per cent of all cancers could be prevented by lifestyle measures, vaccinations or environmental factors.

A new study is seeking to harness the potential of weight-loss drugs without some of the unwelcome side-effects, in a £1.2 million research The anti-diabetic medication semaglutide, also known