Epilepsy
Epilepsy Writing in The Conversation, Dr Sophie Adler (UCL Great Ormond Street Institute of Child Health) and Dr Konrad Wagstyl (UCL Queen Square Institute of Neurology) discuss a new algorithm, which can help find subtle brain abnormalities, known as focal cortical dysplasia. Around 50 million people worldwide have epilepsy. While anti-seizure medications are available and effective for the majority of people with the condition, 20%-30% don't respond to medications. Abnormalities in the brain are one of the leading causes of this drug-resistant epilepsy, which is usually identified by MRI scans before surgery is carried out to cure the patient. However, identifying these abnormal areas from MRIs is an ongoing challenge for clinicians, as these scans can look normal. We wanted to see if an artificial intelligence (AI) algorithm could help find these subtle brain abnormalities (known as focal cortical dysplasia or FCD). Our results, published in the journal Brain , show the AI was successful in detecting abnormalities in two thirds more cases than MRI scans alone.
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