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(Image: Pixabay CC0) - What factors influence the life expectancy of patients with advanced gastric cancer? Scientists at Leipzig University Hospital have discovered that the body's inflammatory response is accompanied by reduced muscle quality in patients and ultimately constitutes the decisive factor for the prognosis. Their results have been published in the -Annals of Oncology-. A research group at Leipzig University Hospital, led by Professor Ulrich Hacker, together with scientists from Masaryk University in Brno, Czech Republic, has investigated what influences the life expectancy of patients with advanced gastric cancer. The evaluation included data from over 500 individuals who had been treated within a clinical trial several years ago. Their analysis used certain values in the blood that indicate an inflammatory response in the body, as well as measurements of muscle quality. -From our findings, it can be concluded that in aggressive, advanced tumour diseases, as exemplified by gastric carcinoma, the inflammatory response in the blood is the driving factor for disease progression. This is closely related to the development of sarcopenia, a loss of muscle mass and quality,- explains Professor Hacker, senior physician at Leipzig University Hospital.
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