Novel nanoparticles with potential for enhanced deep tumour therapy

Artist’s impression of applying a 20 nanometre multi-layered nanoparticle
Artist’s impression of applying a 20 nanometre multi-layered nanoparticle for therapy of deep cancer tissue. When injected in the body, the particles attach at the tumour site and assist in localization and therapy. Image: University of Amsterdam.
Artist's impression of applying a 20 nanometre multi-layered nanoparticle for therapy of deep cancer tissue. When injected in the body, the particles attach at the tumour site and assist in localization and therapy. Image: University of Amsterdam. Patent pending for combination of scintillation and upconversion luminescence Researchers Dr Yansong Feng and Prof. Hong Zhang at the Van 't Hoff Institute for Molecular Sciences at the University of Amsterdam (UvA) have designed and synthesized novel multi-layered, multi-functional nanoparticles that enable a combination of radiotherapy and photodynamic therapy for deep cancer tissue. An initial pre-clinical evaluation of the particles has demonstrated their therapeutic potential. A patent is pending, and the university is now seeking partners for further development or licensing. The novelty of the nanoparticles is that they enable radiotherapy and photodynamic therapy to be combined while using only X-rays.
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